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Patent # Description
2018/0369308 CHINESE HERBAL MEDICINE COMPOSITION HAVING A FUNCTION OF RELIEVING HYPOTHYROIDISM, PREPARATION METHOD AND USE...
The present disclosure relates to the field of health care product and food technology, disclosing a Chinese herbal medicine composition having a function of...
2018/0369307 HERBAL FORMULATION FOR REGENERATING CARDIOMYOCYTES BY REDUCING THE AFTER EFFECTS OF MYOCARDIAL INFARCTION
An herbal formulation employing a plurality of ingredients extracted from a plurality of herbs for the regeneration of cardiomyocytes by reducing the after...
2018/0369306 COMPOSITIONS AND METHODS FOR TREATING MEMORY LOSS AND DIMINISHED COGNITION
The present disclosure is a compound, a method of making the compound and method of using such compound preferably in the form of a dietary supplement that,...
2018/0369305 METHODS OF MITIGATING THE NEGATIVE EFFECTS OF ENDURANCE EXERCISE
Methods for inhibiting exercise-induced production of cortisol, exercise-induced production of myeloperoxidase, exercise-induced production of creatine kinase,...
2018/0369304 VIRUS ENCODING AN ANTI-TCR-COMPLEX ANTIBODY OR FRAGMENT
The present disclosure relates to a replication deficient oncolytic viral vector or replication capable oncolytic virus encoding an antibody or a binding...
2018/0369303 ONCOLYTIC RHABDOVIRUS
Embodiments of the invention include compositions and methods related to non-VSV rhabdoviruses and their use as anti-cancer therapeutics. Such rhabdoviruses...
2018/0369302 EPIZOOTIC HEMORRHAGIC DISEASE VIRUS - TEL AVIV UNIVERSITY (EHDV-TAU) - ONCOLYTIC VIRUS FOR TREATING CANCER
The present invention relates to a unique oncolytic virus, Epizootic Hemorrhagic Disease virus-Tel Aviv University (EHDV-TAU), and to methods and...
2018/0369301 Oncolytic Herpes Simplex Virus and Therapeutic Uses Thereof
The present invention relates to variants of herpes simplex virus (HSV) that selectively infect and replicate in cancer cells, including HSV strains that...
2018/0369300 NOVEL PASTEURELLA MULTOCIDA BACTERIOPHAGE PAS-MUP-1 AND USE THEREOF FOR INHIBITING PROLIFERATION OF PASTEURELLA...
The present invention relates to: Myoviridae bacteriophage Pas-MUP-1 (accession number KCTC 12706BP) which has the capability to specifically destroy...
2018/0369299 NOVEL VIBRIO PARAHAEMOLYTICUS BACTERIOPHAGE VIB-PAP-1 AND USE THEREOF FOR INHIBITING PROLIFERATION OF VIBRIO...
The present invention relates to: Podoviridae bacteriophage Vib-PAP-1 (accession number KCTC 12817BP) which has the capability to specifically destroy Vibrio...
2018/0369298 AN AGENT FOR PROMOTING THE GROWTH OF, AND/OR SUPPRESSING A DECREASE IN, BIFIDOBACTERIUM BACTERIA AND/OR LACTIC...
To provide a technology capable of promoting growth of Bifidobacterium bacteria and lactic acid bacteria under an environment causing the growth or no change...
2018/0369297 TREATMENT OF INTRAHEPATIC CHOLESTASIS AND RELATED LIVER DISEASES
The invention is directed to a method of treating or reducing the risk of intrahepatic cholestasis in a subject in need thereof, comprising administering to...
2018/0369296 Products and Methods for Therapeutic Administration of Microorganisms to Non-Human Animals
Embodiments of the invention encompass identification and characterization of microbiota having potential or demonstrated therapeutic effects for certain...
2018/0369295 Compositions for Fecal Floral Transplantation and Methods for Making and Using Them and Devices for Delivering Them
In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage,...
2018/0369294 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising one or more bacterial strains for treating or preventing visceral hypersensitivity.
2018/0369293 COMPOSITIONS COMPRISING BACTERIAL STRAINS
Provided are compositions comprising a bacterial strain of the genus Blautia, for use in a method of increasing the microbiota diversity and/or inducing...
2018/0369292 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising one or more bacterial strains for treating preventing diarrhea and/or constipation.
2018/0369291 HEPATOCYTES WITH HIGH REGENERATIVE CAPACITY FOR LIVER REPAIR
The invention provides purified mammalian hybrid hepatocyte (HybHP) cells, compositions comprising HybHP cells, methods for purifying HybHP cells, methods for...
2018/0369290 Methods for Differentiating and Purifying Pancreatic Endocrine Cells
The present invention relates to compositions and methods comprising cell surface markers for pluripotent-derived cells, in particular, pancreatic ...
2018/0369288 CARDIAC CELL CULTURE MATERIAL
The purpose of the present invention is to provide a cardiac cell culture material which specifically acts on cardiac cells. In addition, another purpose of...
2018/0369287 NEURAL PRECURSOR CELL POPULATIONS AND USES THEREOF
The present invention provides cell populations enriched for specific neural precursor markers and methods of using such cell populations for treatment of...
2018/0369286 TREATMENT OF EXCESSIVE NEOVASCULARIZATION
The present invention relates to methods of treating or preventing angiogenesis-related diseases by the administration of stem cells and/or progeny cells thereof.
2018/0369285 Specific Chimeric Antigen Receptor T Cells Targeting To NKG2DL, Its Preparation Method and Application Thereof
A chimeric antigen receptor targeting to NKG2DL, its encoding sequence, and its modified immune response cells, and the preparation and application of them....
2018/0369284 Methods Of Making And Using Embryonic Mesenchymal Progenitor Cells
The disclosure provides a method of generating non-clustered stem cells. Cluster disruption prior to mesoderm differentiation increases yield and efficiency in...
2018/0369283 METHODS OF CONDITIONING PATIENTS FOR T CELL THERAPY
The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes a method of conditioning a...
2018/0369282 GENE-MODIFIED LYMPHOCYTES EXPRESSING CHIMERIC ANTIGEN RECEPTOR IN WHICH PRODUCTION OF INFLAMMATORY CYTOKINES IS...
With the aim of improving the treatment result of CAR therapy, intended is to provide an effective means for the cytokine release syndrome, as an alternative...
2018/0369281 METHOD OF AMELIORATING SIDE EFFECTS OF SICKLE CELL DISEASE TREATMENTS
A method of reducing a cerebral tissue pathology associated with a sickle cell disease therapy in a subject is provided using (i) a synthetic high-oxygen...
2018/0369280 HIGH AFFINITY T CELL RECEPTORS AND USES THEREOF
The present disclosure provides TCRs with high or enhanced affinity against various tumor associated antigens (including human Wilms tumor protein 1 (WT 1)...
2018/0369279 ZEOLITE MOLECULAR SIEVES FOR THE REMOVAL OF TOXINS
Medical use of natural and synthetic zeolites for treatment, prevention, and palliation in humans or animals of deleterious concentrations of ammonia,...
2018/0369278 CARBON MONOXIDE-BASED THERAPIES AND IMPLANTABLE DEVICES FOR THE TREATMENT OF VASCULAR DISEASE
Disclosed herein are methods of treating venous thrombosis and vascular inflammation through administration of carbon monoxide and/or a carbon monoxide...
2018/0369277 Compositions Comprising Citrate and Applications Thereof
In one aspect, methods of promoting bone growth are described herein. In some embodiments, a method of promoting bone growth described herein comprises...
2018/0369276 ENVIRONMENT-RESPONSIVE HYALURONIC ACID NANOPARTICLES
The present invention relates to glucose-responsive hyaluronic acid nanoparticles having boronic acid compounds chemically bonded thereto, and a composition...
2018/0369275 ANTISENSE OLIGOMERS FOR TREATMENT OF AUTOSOMAL DOMINANT MENTAL RETARDATION-5 AND DRAVET SYNDROME
Provided herein are methods and compositions for treating a subject in need thereof, such as a subject with deficient SYNGAP1 protein or SCN1A protein...
2018/0369274 RNA INTERFERENCE AGENTS FOR GST-PI GENE MODULATION
This invention provides compounds, compositions and methods for modulating the expression of human GST-.pi. using RNA interference. The RNA interference...
2018/0369273 Pharmaceutical Composition and Applications Thereof
A pharmaceutical composition, comprises micro RNAs with or without chemical modification, and a carrier suitable for delivery in vivo, the carrier is a...
2018/0369272 Biochemical Scaffolds for Modulating Cell Function
A biochemical scaffold for regulating mammalian cell function, including a bioenergetic platform and a vibrational platform, the bioenergetic platform...
2018/0369271 METHODS OF DELIVERING OLIGONUCLEOTIDES TO IMMUNE CELLS
The invention relates to the field of delivery of nucleic acid-based agents to immune cells.
2018/0369270 HEPAROSAN-POLYPEPTIDE AND HEPAROSAN-POLYNUCLEOTIDE DRUG CONJUGATES AND METHODS OF MAKING AND USING SAME
Compositions containing conjugates of heparosan polymer with at least one drug are disclosed, along with methods of production and use thereof.
2018/0369269 ANTIBODIES THAT SPECIFICALLY BLOCK THE BIOLOGICAL ACTIVITY OF A TUMOR ANTIGEN
Novel monoclonal antibodies that specifically bind to KAAG1 are described. In some embodiments, the antibodies block the biological activity of KAAG1 and are...
2018/0369268 METHODS FOR IDENTIFYING INHIBITORS OF "STIMULATOR OF INTERFERON GENE"- DEPENDENT INTERFERON PRODUCTION
The present invention relates to the use cyclic-di-nucleotide and related scaffold molecules that measurably inhibit STING signaling, and methods for their use...
2018/0369267 DRUG FORMULATIONS
The invention provides derivatives of decitabine with superior chemical stability and shelf life, with similar physiological activity. The derivatives are...
2018/0369266 FORMULATIONS OF PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDE DRUGS
This invention relates to pharmaceutical formulations and formulation strategies of protides (phosphoramidate derivatives of nucleosides) and, in particular,...
2018/0369265 CYTARABINE CONJUGATES FOR CANCER THERAPY
Provided relates to conjugates including cytarabine and an amino acid for use in the treatment of cancer. Further, the subject matter relates to conjugates of...
2018/0369264 COMBINATION OF A CARDIAC STEROID AND AN AKT INHIBITOR FOR THE TREATMENT OF CARDIOVASCULAR DISEASES AND DISORDERS
The present invention relates to pharmaceutical combinations for the treatment of cardiovascular diseases and disorders. More particularly, the invention...
2018/0369263 THERAPEUTIC METHOD AND THERAPEUTIC AGENT FOR ATOPIC DERMATITIS IN ANIMALS
Provided are a therapeutic agent and a therapeutic method for canine atopic dermatitis. The therapeutic method for atopic dermatitis in animals and the...
2018/0369262 METHODS FOR TREATING RESISTANT DISEASES USING TRIAZOLE CONTAINING MACROLIDES
Triazole-containing macrolide and ketolide antibiotics, therapeutic compositions containing them and methods of use for treating diseases caused by one or more...
2018/0369261 USE OF N-ACETYLGLUCOSAMINE AND DERIVATIVES THEREOF TO TREAT MUSCLE DISORDERS
Methods of preventing or delaying the weakening of as well as improving the strengthening of muscles includes the step of providing an effective amount or dose...
2018/0369260 SYNTHETIC COMPOSITION AND METHOD FOR MODULATING BRAIN FUNCTION AND BEHAVIOUR
A synthetic composition for use in improving one or more co-morbid mental disorder symptoms of a patient with IBS, characterised in that the composition...
2018/0369259 COMBINATION THERAPY EFFECTIVE AGAINST MICROORGANISMS, INCLUDING DRUG RESISTANT MICROORGANISMS
Novel antimicrobial compositions comprise at least a form of a fosfomycin (or suitable analogs, or derivatives thereof), and at least one sulfonamide (or...
2018/0369258 ANTI-BACTERIAL COMPOUNDS BASED ON AMINO-GOLD PHOSPHINE COMPLEXES
A compound of formula (I) for use in the prevention or treatment of a bacterial infection wherein: P.sup.X is selected from the group consisting of (P1), (P2)...
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