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Patent # Description
2019/0002970 MULTIPLE TAGGING OF INDIVIDUAL LONG DNA FRAGMENTS
This disclosure provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence...
2019/0002969 MULTIPLE TAGGING OF LONG DNA FRAGMENTS
The present invention provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence...
2019/0002968 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION
The present disclosure relates to compositions and methods based on polypeptide-tagged nucleotide, and the use of such polypeptide-tagged nucleotides in...
2019/0002967 Methods of Amplifying Nucleic Acid Sequences
Methods are provided for nucleic acid amplification including contacting a double stranded nucleic acid with transposases bound to transposon DNA, wherein the...
2019/0002966 DETECTION OF CHROMOSOME ABNORMALITIES
Embodiments of the present invention provide a computer-implemented method of determining a probability of a fetal chromosomal abnormality, the method...
2019/0002965 AMPLIFICATION AND ANALYSIS OF SELECTED TARGETS ON SOLID SUPPORTS
Methods are provided for multiplexed amplification of selected targets and analysis of the amplified targets. In preferred aspects the amplification and...
2019/0002964 BODILY FLUID TARGET ENRICHMENT
The invention provides methods for capturing target nucleic acid directly from bodily fluid samples, without the need for certain complex sample preparation...
2019/0002963 MULTIPLEXED FLUOROMETRIC MEASUREMENTS WITH DROPLET PCR SYSTEMS
The present disclosure provides methods and compositions for detection of multiple nucleic acid targets in a single optical channel in a digital assay. In some...
2019/0002962 GENE-MATCHED ENRICHMENT AND POLYMERASE CHAIN REACTION FOR RAPID DETECTION OF MICROORGANISMS
A method for amplifying and detecting microorganisms, such as species of Listeria, is described. The method utilizes gene-matched enrichment media and...
2019/0002961 DETECTION OF NEISSERIA GONORRHOEAES
Methods and compositions for detection of Neisseria gonorrhoeae are disclosed herein. In some embodiments, the presence or absence of N. gonorrhoeae in a...
2019/0002960 GENETIC TESTING FOR ALIGNMENT-FREE PREDICTING RESISTANCE OF MICROORGANISMS AGAINST ANTIMICROBIAL AGENTS
The present invention relates to a method of determining an infection of a patient with at least one microorganism, particularly a bacterial microorganism,...
2019/0002959 SYSTEM AND METHOD FOR PROCESSING BIOLOGICAL SAMPLES
A system and method for processing and detecting nucleic acids from a set of biological samples, comprising: a molecular diagnostic module configured to...
2019/0002958 MODULATION OF ACCESSIBILITY OF HOST NUCLEIC ACIDS TO NUCLEIC ACID DIGESTING ENZYMES IN ACELLULAR BIOLOGICAL FLUIDS
Disclosed is a method for isolating, amplifying, and sequencing infectious agents' nucleic acids from an acellular fraction of a biological fluid using...
2019/0002957 NUCLEIC ACID AMPLIFICATION
The present invention provides methods for the amplification of nucleic acid molecules. Methods for amplifying target polynucleotides, including mRNA, using...
2019/0002956 SYSTEM AND METHOD FOR DROPLET DETECTION
Systems and methods for detection of a signal from droplets of an emulsion. An exemplary system may comprise a fluid transporter having a tube with an open end...
2019/0002955 APPARATUS FOR AMPLIFICATION OF NUCLEIC ACIDS
Described herein is a chip-based apparatus for amplifying nucleic acids, a cartridge housing the apparatus, and methods of using the apparatus for ...
2019/0002954 EXTREME REVERSE TRANSCRIPTION PCR
Methods, kits and mixtures are provided for performing RT-PCR with an RT incubation of no more than one minute and PCR cycles in <20 seconds per cycle.
2019/0002953 A NOVEL METHOD FOR THE PREPARATION OF BAR-CODED PRIMER SETS
The present invention relates to a method of producing a set of primers suitable for the reverse transcription and/or amplification of a plurality (N) of...
2019/0002952 COMPOSITIONS AND METHODS FOR DIAGNOSIS OF SHOCK
Methods and kits for diagnosis and staging of shock, and especially non-septic shock are presented in which protease activities and/or volatile compounds are...
2019/0002951 SYSTEMS AND METHODS FOR CONFIRMING ACTIVATION OF BIOLOGICAL INDICATORS
Biological indicators may be improperly activated. The disclosed subject matter is directed to methods of confirming that a biological indicator having an...
2019/0002950 METHOD AND SYSTEM FOR IMAGING A BLOOD SAMPLE
Apparatus and methods are described including introducing a cell suspension comprising red blood cells into a carrier that is a closed cavity that includes a...
2019/0002949 COMPOSITIONS AND METHODS FOR MEASURING BLOOD GLUCOSE LEVELS
In some embodiments, the present invention a mutated FAD-GDHa protein, wherein the mutated FAD-GDHa protein is mutated from a wild-type first species to...
2019/0002948 METHOD AND ELECTRONIC DEVICE FOR DETERMINING THE CONCENTRATION OF AN ANALYTE
A method is provided for determining, the presence and concentration of an analyte by contacting said sample with a solution comprising: magnetic beads, a...
2019/0002947 RECOMBINANT PRODUCTION METHOD
Herein is reported a method for the recombinant production of a polypeptide in a eukaryotic cell comprising the steps of (i) cultivating a eukaryotic cell...
2019/0002946 METHODS FOR INCREASING MANNOSE CONTENT OF RECOMBINANT PROTEINS
The present invention relates to methods of upregulating the high mannose glycoform content of a recombinant protein during a mammalian cell culture by...
2019/0002945 GENERATION AND COMPARATIVE KINETIC ANALYSIS OF NEW GLYCOSYNTHASE MUTANTS FROM STREPTOCOCCUS PYOGENES...
The present invention provides for recombinant Endo-S mutants (named Endo-S glycosynthases) that exhibit reduced hydrolysis activity and increased...
2019/0002944 ACOUSTIC ENERGY MEDIATION OF GENETIC FRAGMENTATION
Method and apparatus for controlling acoustic treatment of a sample to mediate a tagmentation process used on double stranded DNA.
2019/0002943 SYSTEM AND METHOD FOR SYNTHESIS OF DNA PARTICLES AND USE THEREOF
Disclosed is a system and method for production of DNA particles and use thereof. The DNA particles can be produced by amplification of nucleic acid...
2019/0002942 ANTIBIOTIC FIIRV 104/18 COMPLEX AND THE ISOLATED INDIVIDUAL FACTORS THEREOF
An antibiotic FIIRV 104/18 complex comprising factors F793, F795, F797, F813 and F683, of formula (I), wherein R represents a glycosidic radical as defined in...
2019/0002941 Cellulolytic enzyme compositions and uses thereof
The present invention relates to recombinant filamentous fungal host cells producing cellulolytic enzyme compositions and methods of producing and using the...
2019/0002940 USING DISSOLVED OXYGEN TO INHIBIT LACTIC ACID PRODUCTION DURING PROPAGATION OF YEAST AND/OR HYDROLYSIS OF...
Embodiments of the present disclosure involve systems and methods that inhibit the production of lactic acid during propagation of yeast and/or during...
2019/0002939 Highly Efficient Method for Synthesizing Difructose Anhydride III
The invention discloses a high-efficiency synthesis method of difructose anhydride III. The method comprises the following steps: firstly converting sucrose...
2019/0002938 PROCESS FOR PRODUCING GELLAN GUM
The invention provides a new fermentation process for producing gellan gum, which can control the feeding amount and feeding speed of the nitrogen sources...
2019/0002937 IMPROVED GRANULAR STARCH CONVERSION ENZYMES AND METHODS
Described are methods and compositions relating to granular starch-converting glucoamylases and .alpha.-amylases. The enzymes can be used to perform enzymatic...
2019/0002936 TRANSGENIC MICROORGANISMS AND SYNTHESIS OF PIPERAZIC ACID, PIPERAZIC ACID CONTAINING PRODUCTS, AND DERIVATIVES...
Among the various aspects of the present disclosure is the provision of a biological and biochemical production of piperazic acid derived from the newly...
2019/0002935 BACTERIAL CELLS WITH IMPROVED TOLERANCE TO POLYAMINES
Provided are bacterial cells genetically modified to improve their tolerance to certain commodity chemicals, such as polyamines, and methods of preparing and...
2019/0002933 RECOMBINANT YEAST CELLS PRODUCING POLYLACTIC ACID AND USES THEREOF
The present invention relates to a recombinant yeast cell comprising a gene encoding a protein exhibiting lactyl-CoA synthase activity and a gene encoding a...
2019/0002932 METHOD FOR SYNTHESISING ORGANIC MOLECULES
Disclosed is a method for synthesising organic molecules from carbon-containing sources and dihydrogen, as well as a device for implementing the method. The...
2019/0002931 METHOD FOR PRODUCING COMPOUND DERIVED FROM HERBACEOUS PLANT OF FAMILY GRAMINEAE OR CUCURBITACEAE
The production method of the present invention includes: a first fermentation step of adding at least one microorganism selected from yeast, Escherichia coli,...
2019/0002930 WET OXIDATION OF BIOMASS
A process for producing a transportation fuel from a lignocellulosic feedstock comprising subjecting a stream comprising lignin to a wet oxidation that...
2019/0002929 METHOD FOR THE SIMULTANEOUS PRODUCTION OF ETHANOL AND A FERMENTED, SOLID PRODUCT
The invention relates to a method for the simultaneous production of a fermented, solid product and ethanol comprising the following steps: 1) providing a...
2019/0002928 Grain Processing
The present invention provides a process for producing biogas and/or methane from solid spent cereal products derived from, for example, the mashing process of...
2019/0002927 METHODS, SYNTHETIC HOSTS AND REAGENTS FOR THE BIOSYNTHESIS OF HYDROCARBONS
Systems, networks, methods, compositions and recombinant hosts for biosynthesizing hydrocarbons from a feedstock, such as gas, are provided.
2019/0002926 METHODS, MATERIALS, SYNTHETIC HOSTS AND REAGENTS FOR THE BIOSYNTHESIS OF HYDROCARBONS AND DERIVATIVES THEREOF
Genetically engineered hosts and methods for their production and use in synthesizing hydrocarbons are provided.
2019/0002925 PRODUCTION OF MANOOL
Provided herein are methods of producing (+)-manool comprising: contacting geranylgeranyl diphosphate with an copalyl diphosphate (CPP) synthase to form a (9S,...
2019/0002924 System for hydrogen production under limited aerobic conditions
The present invention provides a method for fermentative hydrogen production under limited aerobic conditions by utilizing the respiratory interaction between...
2019/0002923 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific...
2019/0002922 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific...
2019/0002921 METHODS AND COMPOSITIONS FOR RNA-DIRECTED TARGET DNA MODIFICATION AND FOR RNA-DIRECTED MODULATION OF TRANSCRIPTION
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific...
2019/0002920 METHODS AND KITS FOR CLONING-FREE GENOME EDITING
The methods and compositions provided herein improve upon the methods presently used for targeted genomic modification, in part, by removing the requirement...
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