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Patent # Description
2019/0000944 MESOTHELIN CHIMERIC ANTIGEN RECEPTOR (CAR) AND ANTIBODY AGAINST PD-L1 INHIBITOR FOR COMBINED USE IN ANTICANCER...
Provided are compositions for use in methods for treating diseases associated with expression of mesothelin comprising administering a cell that expresses a...
2019/0000943 AAV6 VECTORS FOR IMMUNOTHERAPY
Provided herein are nucleic acids, recombinant adeno-associated virus (rAAV) particles, and compositions, as well as methods of use thereof for inducing immune...
2019/0000942 METHOD OF TREATING FUNGAL INFECTION
A vaccine comprising Calnexin fragment and a method of using the vaccine to immunize a patient against fungi are disclosed. The Calnexin fragment may be either...
2019/0000941 METHOD OF TREATING A MAMMAL, INCLUDING HUMAN, AGAINST CANCER USING METHIONINE AND ASPARAGINE DEPLETION
The invention is related to a new method for treating liquid and solid cancers, in a mammal, including human, wherein methioninase is administered before...
2019/0000940 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AADC DEFICIENCY
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment,...
2019/0000939 COMPOSITIONS OF ENGINEERED HUMAN ARGINASES AND METHODS FOR TREATING CANCER
Compositions and methods for the treatment of cancer are described, and, more preferably, to the treatment of cancers that do not express, or are otherwise...
2019/0000938 USE OF BOTULINUM NEUROTOXIN IN THE TREATMENT OF SIALORRHEA
This invention relates to improved uses of botulinum neurotoxins in the treatment of sialorrhea or diseases or conditions relating to increased saliva...
2019/0000937 BOTULINUM TOXIN FOR USE IN THE TREATMENT OF PARATONIA
The present invention relates to botulinum toxins for use in the treatment of paratonia. In particular, the present invention relates to the treatment of...
2019/0000936 PROPHYLACTIC NORMALIZATION OF CUTANEOUS WOUND REPAIR
The present invention relates to methods of inhibiting scar formation in a skin wound as well as methods of promoting tissue regeneration in a skin wound in a...
2019/0000935 DISSOLVING FILM FOR DELIVERY OF AN ACTIVE AGENT
A biodegradable film comprising a therapeutically effective amount of a Clostridial neurotoxin is described. Methods for treating rhinitis and for treating a...
2019/0000933 POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE
The invention relates to mRNA therapy for the treatment of Fabry disease. mRNAs for use in the invention, when administered in vivo, encode human the...
2019/0000932 POLYNUCLEOTIDES ENCODING ALPHA-GALACTOSIDASE A FOR THE TREATMENT OF FABRY DISEASE
The invention relates to mRNA therapy for the treatment of Fabry disease. mRNAs for use in the invention, when administered in vivo, encode human the...
2019/0000931 DIETARY SUPPLEMENTS AND FORMULATIONS
Provided are dietary supplements, formulations, kits and methods for administration to an individual with type II diabetes or at risk of developing type II...
2019/0000930 DIETARY SUPPLEMENTS AND FORMULATIONS
Provided are dietary supplements, formulations, kits and methods for administration to an individual with type II diabetes or at risk of developing type II...
2019/0000929 Hemoglobin Compositions
The invention provides compositions containing hemoglobin, particularly PEGylated hemoglobin. The PEGylated hemoglobin molecule is capable of transferring...
2019/0000928 MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
Methods and compositions are provided for extending the half-life of a therapeutic agent. A modified therapeutic agent (mTA) comprises a therapeutic agent, a...
2019/0000927 NOVEL THERAPY
The present invention relates to relaxin or a homologue or variant thereof for use in a method of treating an inflammatory condition, for example an autoimmune...
2019/0000926 CONTROLLED-RELEASE CNP AGONISTS WITH LOW NPR-C BINDING
The present invention relates to a controlled-release CNP agonist having low NPR-C affinity; to pharmaceutical compositions comprising said controlled-release...
2019/0000925 COMPOSITION FOR TREATING OR PREVENTING INFLAMMATORY DISEASE CONTAINING COMPLEX OF INTERLEUKIN-15/INTERLEUKIN-15...
The present disclosure relates to a composition for treating or preventing an inflammatory disease, and more particularly, to a composition for treating or...
2019/0000924 AMELIORATING SYSTEMIC SCLEROSIS WITH DEATH RECEPTOR AGONISTS
The present disclosure relates to methods and compositions for treating and/or preventing autoimmune fibrosis, such as systemic sclerosis (SSc; scleroderma)....
2019/0000923 METHODS OF TREATING OR AMELIORATING METABOLIC DISORDERS USING GROWTH DIFFERENTIATION FACTOR 15 (GDF-15)
The disclosure relates to the treatment of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), as well as end-stage liver...
2019/0000922 MESENCHYMAL STEM CELL DIFFERENTIATION
The present invention provides for methods and compositions for treating or preventing arthritis and joint injury.
2019/0000921 SEMAPHORIN 3A FOR TREATMENT AND PROGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
The subject matter relates to Semaphorin 3A (Sema3A) and its use in treatment and prognosis of Systemic Lupus Erythematosus (SLE). Provided are, inter-alia,...
2019/0000920 Methods of Treating Cancer
Methods of treating cancers comprising FGFR1 gene amplification are provided. In some embodiments, the methods comprise administering a fibroblast growth...
2019/0000919 PRE-FILLED PHARMACEUTICAL PACKAGE COMPRISING A LIQUID FORMULATION OF A VEGF-ANTAGONIST
A pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist, for example Ranibizumab, in a pre-filled pharmaceutical package, for...
2019/0000918 OCTREOTIDE INJECTION
The present invention relates to a sterile solution comprising: octreotide in the form of a pharmaceutically acceptable salt, present at a concentration...
2019/0000917 METHODS FOR PREVENTING AND TREATING PNEUMOCYSTIS INFECTIONS
The disclosure relates to methods of prophylactic and therapeutic treatments of a Pneumocystis infection (i.e., an infection caused by Pneumocystis jirovecii)...
2019/0000916 COMPOSITIONS AND METHODS FOR MODULATING AT2R ACTIVITY
New polypeptide agonists of AT2R are disclosed, as well as pharmaceutical compositions comprising the agonists, methods of their use in the treatment of...
2019/0000915 METHODS FOR THE REGULATION OF MATRIX METALLOPROTEINASE EXPRESSION
The disclosure provides methods of reducing MMP-9 expression and/or MMP-9 activity in a mammalian subject. The disclosure also provides methods of increasing...
2019/0000914 METHODS OF PRODUCING ANAMORELIN HYDROCHLORIDE HAVING CONTROLLED CHLORIDE CONTENT
The present invention relates to particulate forms of anamorelin monohydrochloride or a composition comprising anamorelin monohydrochloride having controlled...
2019/0000913 NUTRITIONAL COMPOSITIONS COMPRISING HYDROLYZED PROTEIN AND USES THEREOF
Disclosed embodiments provide a method of enhancing maturation of a lung, brain, or both, in an infant. The method includes the step of administering to the...
2019/0000912 COLLAGEN 7 COMPOSITIONS AND METHODS OF USING THE SAME
The present disclosure relates to compositions comprising collagen 7 and methods of using the same to treat DEB.
2019/0000911 HERBAL COMPOSITION FOR HEALING OF WOUND, CUTS AND BURNS AND A METHOD OF SYNTHESIZING THEREOF
The embodiments herein disclose a method for synthesizing an ointment from water plantain for the wounds, cuts and burnt tissues. The water plantain plant...
2019/0000910 METHODS OF TREATING DISEASES USING GRAPE PROTEINS
A food composition for human consumption comprising a plurality of grape ingredients, wherein the plurality of grape ingredients comprise ground flesh, seed,...
2019/0000909 INHIBITING OR INACTIVATING THE VIRULENCE OF A LIVE PATHOGEN
Methods of and compositions for producing and using plant-based materials are provided. The methods include using biopolymers or their synthetic equivalents...
2019/0000908 COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING A URINARY TRACT INFECTION
A composition comprising D-Mannose, Phellodendron Extract and Cranberry is disclosed. The disclosed composition, is useful in treating and preventing a...
2019/0000907 COMPOSITIONS AND METHODS FOR TREATING INSOMNIA AND OTHER SLEEP RELATED DISORDERS
The present disclosure is a composition, a method of making the composition and method of using such composition preferably in the form of a dietary supplement...
2019/0000906 COMPOSITION, CONTAINING EXTRACTS OF DIPSACUS ASPEROIDES AND CYNANCHUM WILFORDII AS ACTIVE INGREDIENTS, FOR...
The present invention relates to a composition, containing extracts of Dipsacus asperoides (Phlomis umbrosa Turcz) and Cynanchum wilfordii as active...
2019/0000905 Gynostemma pentaphyllum fermented extracts comprising Saponins as an active functional food ingredient and...
A method for preparing an extract of fermented Gynostemma pentaphyllum with increased contents of saponins or low-molecular-weight saponins, which includes a...
2019/0000904 BENEFICIAL EFFECT OF BIDENS PILOSA ON FAT DECREASE AND MUSCLE INCREASE
A composition comprising a therapeutically effective amount of Bidens pilosa extract, or an active compound isolated from the Bidens pilosa extract for use in...
2019/0000903 BIOPOLYMER COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF LIVER DISEASE
The invention provides compositions comprising milk thistle, dandelion root, and/or one or more antioxidant amino acids (e.g., n-acetyl L-cysteine) for the...
2019/0000902 PASSION FLOWER SEED EXTRACT, AND COSMETIC, PHARMACEUTICAL OR DERMATOLOGICAL COMPOSITIONS CONTAINING SAME
The invention relates to a polyphenolic extract of passion flower seeds, in particular Passiflora incarnata or Passiflora edulis seeds, comprising at least 30...
2019/0000901 COMPOSITION COMPRISING ULMI CORTEX EXTRACTS FOR INHIBITING OVOTOXICITY
Provided is a method of treating ovotoxicity of an individual, including administering an Ulmi cortex extract to an individual in need of treatment. The...
2019/0000900 Application of anthocyanin extract in preparing pharmaceutical composition for preventing and treating cardiac...
The disclosure provides an application of an anthocyanin extract in preparing a pharmaceutical composition for preventing and treating cardiac toxicity induced...
2019/0000899 ANTI-CANCER ONCOLYTIC VIRUS COMBINATION THERAPIES AND ELITE RESPONDER SELECTION PLATFORMS
Therapeutic methods for administering gut microbiota and oncolytic viruses to a subject are provided. The gut microbiota serve to pre-condition, the subject's...
2019/0000898 COMBINING ADENOVIRUS AND CHEMOTHERAPEUTIC AGENTS FOR TREATING CANCER
The invention relates to oncolytic adenovirus vector and chemotherapeutic agents. More specifically, the invention relates to oncolytic adenovirus vector and...
2019/0000897 NOVEL VIBRIO PARAHAEMOLYTICUS BACTERIOPHAGE VIB-PAP-2 AND USE THEREOF FOR INHIBITING PROLIFERATION OF VIBRIO...
The present invention relates to a Podoviridae bacteriophage Vib-PAP-2 (Accession NO: KCTC 12910BP) that is isolated from the nature and can kill specifically...
2019/0000896 DELIVERY VEHICLE
The invention relates in one aspect to a pharmaceutical composition comprising a nucleic acid delivery vehicle for delivering a deliverable nucleic acid into a...
2019/0000895 COMPOSITION COMPRISING AT LEAST ONE PROBIOTIC BACTERIUM AND INTENDED TO BE USED FOR THE TREATMENT OF BUCCAL MYCOSES
The present invention relates to a composition which comprises at least one probiotic bacterium and which is intended to be used for the preventive and/or...
2019/0000894 PROBIOTIC COMPOSITIONS AND USE THEREOF
Disclosed are probiotic compositions containing Lactobacillus plantarum, Lactobacillus rhamnosus, Bifidobacterium animalis subsp. lactis. Such compositions are...
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