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Patent # | Description |
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2019/0017101 |
FUNCTIONAL LIGANDS TO THC The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for... |
2019/0017100 |
METHOD FOR ANALYSIS OF AN RNA MOLECULE The present invention relates to the field of RNA analysis. In particular, the invention concerns the use of a catalytic nucleic acid molecule for the analysis... |
2019/0017099 |
METHODS AND MATERIALS FOR DETECTING VIRAL OR MICROBIAL INFECTIONS This document provides methods and materials for detecting target nucleic acid. For example, methods and materials for detecting the presence or absence of... |
2019/0017098 |
Sorbents for the Extraction and Stabilization of Nucleic Acids Mesoporous sorbents are effective for storing and transporting nucleic acids. In particular, two ethane-bridged silica sorbents with amine functionalities are... |
2019/0017097 |
HIGH THROUGHPUT OPTICAL ASSAY OF HUMAN MIXED CELL POPULATION SPHEROIDS The present disclosure provides a method of performing a functional assay on human spheroids, e.g., three-dimensional human cell spheroids using, in one... |
2019/0017096 |
PRENYLATION ASSAY A method for determining the activity of Rab escort protein 1 (REP1) comprising the steps: (a) providing a sample comprising REP1; (b) contacting the sample of... |
2019/0017095 |
COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND
VIRUS BINDING AND PENETRATION Disclosed herein are glyco-decoy acceptor compositions that sidetrack or inhibit the activity of biosynthetic enzymes participating in synthesis of ligands... |
2019/0017094 |
METHOD FOR IMMOBILIZATION OF GLUCURONIDASE ENZYMES FOR THE DETECTION OF
PRODUCTS DERIVED FROM GLUCURONIDE COMPOUNDS The present invention provides an insoluble enzymatic reagent for detecting products derived from glucuronide metabolites in a sample, containing an enzyme... |
2019/0017093 |
PROCESS FOR DETERMINING VIABILITY OF TEST MICROORGANISMS OF BIOLOGICAL
INDICATOR AND STERILIZATION DETECTION... A process for determining the viability of a biological indicator includes exposing the biological indicator to a viability detection medium, the biological... |
2019/0017092 |
PROCESS FOR DETERMINING VIABILITY OF TEST MICROORGANISMS OF BIOLOGICAL
INDICATOR AND STERILIZATION DETECTION... A process for determining the viability of a biological indicator includes exposing the biological indicator to a viability detection medium, the biological... |
2019/0017091 |
PROCESS FOR DETERMINING VIABILITY OF TEST MICROORGANISMS OF BIOLOGICAL
INDICATOR AND STERILIZATION DETECTION... A process for determining the viability of a biological indicator includes exposing the biological indicator to a viability detection medium, the biological... |
2019/0017090 |
Rapid Antibiotic Susceptibility Test Using Membrane Fluorescence Staining
and Spectral Intensity Ratio Improved... Single dye fluorescent staining and the combination of differences in both intensity and spectral emission permit determination of the minimum concentration of... |
2019/0017089 |
MYO1A FOR PREDICTING CONVERSION OF ACUTE PAIN INTO CHRONIC PAIN AND USE OF
MYO1A FOR THERAPY OF PAIN The present invention relates to the identification of Myo1a as a biomarker of conversion of acute pain into chronic pain, and as a therapeutic target. The... |
2019/0017088 |
RADIATION SENSOR A radiation sensor, comprising a housing, a first chamber disposed in the housing and configured to contain a microorganism. A second chamber is disposed in... |
2019/0017087 |
COENZYME-LINKED GLUCOSE DEHYDROGENASE AND POLYNUCLEOTIDE ENCODING THE SAME The present invention provides members that produce on a large scale a coenzyme-linked glucose dehydrogenase which has excellent substrate-recognizing ability... |
2019/0017086 |
COENZYME-LINKED GLUCOSE DEHYDROGENASE AND POLYNUCLEOTIDE ENCODING THE SAME The present invention provides members that produce on a large scale a coenzyme-linked glucose dehydrogenase which has excellent substrate-recognizing ability... |
2019/0017085 |
COENZYME-LINKED GLUCOSE DEHYDROGENASE AND POLYNUCLEOTIDE ENCODING THE SAME The present invention provides members that produce on a large scale a coenzyme-linked glucose dehydrogenase which has excellent substrate-recognizing ability... |
2019/0017084 |
MULTIPLE STAGE ISOTHERMAL ENZYMATIC AMPLIFICATION Disclosed herein are methods for multiple stage isothermal amplification of nucleic acid comprising a first substantially isothermal amplification reaction on... |
2019/0017083 |
ENZYMATIC PRODUCTION OF D-TAGATOSE The current disclosure provides a process for enzymatically converting a saccharide into tagatose. The invention also relates to a process for preparing... |
2019/0017082 |
INCREASED TRIACYLGLYCEROL PRODUCTION IN MICROALGAE The application generally relates to bioproduction of molecules of interest in micro- organisms, more particularly in microalgae. In particular, the... |
2019/0017081 |
METHODS AND COMPOSITIONS FOR PRODUCING FATTY ALCOHOLS Methods and compositions, including nucleotide sequences, amino acid sequences, and host cells, for producing fatty alcohols are described. |
2019/0017080 |
PROCESSES FOR RECOVERING PRODUCTS FROM A CORN FERMENTATION MASH Processes and systems for recovering products from a fermentation mash. In some examples, a process for recovering products from a fermentation mash can... |
2019/0017079 |
METHOD FOR FERMENTING SUGARS In a first aspect of the present invention, there is provided a fermentation process for fermenting a carbon source comprising glucose and one or more... |
2019/0017078 |
MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS
BY FORMATE ASSIMILATION Provided herein are non-naturally occurring microbial organisms having a formaldehyde fixation pathway and a formate assimilation pathway, which can further... |
2019/0017077 |
MICROBIAL ENGINEERING FOR THE PRODUCTION OF CHEMICAL AND PHARMACEUTICAL
PRODUCTS FROM THE ISOPRENOID PATHWAY The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids. |
2019/0017076 |
METHODS, CELLS AND REAGENTS FOR PRODUCTION OF ISOPRENE, DERIVATIVES AND
INTERMEDIATES THEREOF This application describes methods, including non-naturally occurring methods, for biosynthesizing 3-hydroxy-3-methylglutaryl-coA and intermediates thereof, as... |
2019/0017075 |
ENGINEERED MEGANUCLEASES WITH RECOGNITION SEQUENCES FOUND IN THE HUMAN
BETA-2 MICROGLOBULIN GENE Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human beta-2 microglobulin gene. The... |
2019/0017074 |
METHODS FOR GENOMIC INTEGRATION Provided herein are methods of integrating one or more exogenous nucleic acids into one or more selected target sites of a host cell genome. In certain... |
2019/0017073 |
COMPOSITIONS AND METHODS FOR DELIVERING NUCLEIC ACID TO A CELL Provided are novel compositions useful for delivering nucleic acids to cells. Also provided are methods for making and using such compositions. |
2019/0017072 |
INTRACELLULAR DELIVERY OF COMPLEXES The present invention provides methods for delivering a transient and/or reversible complex into a cell including passing a cell suspension through a... |
2019/0017071 |
METHOD FOR THE OPTOINJECTION OF EXOGENOUS MATERIAL INTO A BIOLOGICAL CELL A method for the optoinjection of exogenous material in a recipient biological cell is disclosed and comprises: placing a biological cell on a planar surface... |
2019/0017070 |
STRAIN PTODUCING ALLOSE FROM FRUCTOSE AND METHOD FOR PRODUCING ALLOSE
USING SAME The present invention relates to a recombinant strain for producing an allose from a fructose, a composition for producing an allose which produces an allose... |
2019/0017069 |
ADENO-ASSOCIATED VIRUS VECTORS FOR TREATMENT OF GLYCOGEN STORAGE DISEASE The present disclosure describes improved adeno-associated virus (AAV) vectors for gene therapy applications in the treatment of glycogen storage disease,... |
2019/0017068 |
ADENO-ASSOCIATED VIRUS (AAV) SEROTYPE 8 SEQUENCES, VECTORS CONTAINING
SAME, AND USES THEREFOR Sequences of a serotype 8 adeno-associated virus and vectors and host cells containing these sequences are provided. Also described are methods of using such... |
2019/0017067 |
GLYPHOSATE TOLERANT PLANTS HAVING MODIFIED
5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE GENE REGULATION This document provides methods and materials related to plants (e.g., nontransgenic plants) that are tolerant to glyphosate-based herbicides. For example,... |
2019/0017066 |
HERBICIDE TOLERANCE GENES AND METHODS OF USE THEREOF Polypeptides and recombinant DNA molecules useful for conferring tolerance to AOPP herbicides, phenoxy acid herbicides, and pyridinyloxy acid herbicides are... |
2019/0017065 |
METHOD FOR MODIFYING LATERAL BUDDING IN PLANTS AND PLANTS RESULTING FROM
SAID METHOD The present invention relates to a method for modifying lateral budding in a plant comprising modifying the expression or function of a protein comprising the... |
2019/0017063 |
PLANTS WITH MODIFIED TRAITS The present invention relates to transgenic plants, or parts thereof, with modified traits, as well as methods of selecting and using these plants or parts. In... |
2019/0017062 |
NUCLEIC ACID SEQUENCES ENCODING TRANSCRIPTION FACTORS REGULATING ALKALOID
BIOSYNTHESIS AND THEIR USE IN... Plant metabolism and alkaloid levels can be regulated by transcription factors that regulate the nicotinic alkaloid biosynthetic pathway. In one embodiment,... |
2019/0017061 |
AP2 DOMAIN TRANSCRIPTION FACTOR ODP2 (OVULE DEVELOPMENT PROTEIN 2) AND
METHODS OF USE Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2... |
2019/0017060 |
MANIPULATION OF PROANTHOCYANIDIN (PA) COMPOSITION BY AFFECTING
ANTHOCYANIDIN SYNTHASE (ANS) AND... Using methods described in preferred embodiments, the composition of proanthocyanidins (PAs) in plants can be modified to produce plants that produce PAs with... |
2019/0017059 |
METHOD FOR MODIFYING LATERAL BUDDING The present invention relates to a method for modifying lateral budding in a plant comprising modifying the expression or function of a protein comprising the... |
2019/0017058 |
CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE
MANIPULATION The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and... |
2019/0017057 |
LIVE BACTERIAL VECTORS FOR PROPHYLAXIS OR TREATMENT A live bacterium, having a DNA construct stabilized against transduction of other bacteria, having a promoter sequence and encoding a fusion peptide,... |
2019/0017056 |
NOVEL TRANSPOSON THAT PROMOTES FUNCTIONAL DNA EXPRESSION IN EPISOMAL DNAS
AND METHOD TO ENHANCE DNA... A transposon (TnC_T7) was developed to partially supply the transcriptional machinery during functional analysis of genomic/metagenomic libraries. This... |
2019/0017055 |
REAL-TIME REPORTER SYSTEMS FOR MONITORING BASE EDITING Real-time systems for monitoring base editing in living cells, including base editing by APOBEC-Cas9 fusions, is provided herein. |
2019/0017054 |
METHOD OF MODULATING SURVIVAL AND STEMNESS OF CANCER STEM CELLS BY
MDA-9/SYNTENIN (SDCBP) This invention discloses a method of modulating the survival and stemness of cancer stem cells (CSCs) by modulating the expression of MDA-9/Syntenin (SDCBP),... |
2019/0017053 |
TREATMENT USING TRUNCATED TRK B AND TRK C ANTAGONISTS Disclosed herein are methods, compositions, vectors, and kits comprising an antagonist of a truncated TrkC or a truncated TrkB. Also described herein are... |
2019/0017052 |
Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in
Treatment of Disease Methods and compositions are disclosed for controlling expression of TNF receptors (TNFR1 and TNFR2) and of other receptors in the TNFR superfamily using... |
2019/0017051 |
OLIGONUCLEOTIDE COMPOSITIONS WITH ENHANCED EFFICIENCY The oligonucleotide compositions of the present invention make use of combinations of oligonucleotides. In one aspect, the invention features an... |