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| Patent # | Description |
|---|---|
| 2019/0017050 |
ENGINEERED IMMUNOSTIMULATORY BACTERIAL STRAINS AND USES THEREOF Provided are immunostimulatory bacteria and pharmaceutical compositions containing the bacteria. The immunostimulatory bacteria provided herein contain one or... |
| 2019/0017049 |
METHODS AND COMPOSITIONS TO INHIBIT METASTASIS AND TO TREAT FIBROSIS AND
TO ENHANCE WOUND HEALING Methods and compositions are provided for inhibiting or treating metastasis based on discoveries regarding Kifl9 and Cep192. Methods and compositions are... |
| 2019/0017048 |
ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF USHER SYNDROME TYPE 2 The invention relates to the fields of medicine and immunology. In particular, it relates to novel antisense oligonucleotides that may be used in the... |
| 2019/0017047 |
METHODS FOR MODULATING ATAXIN 2 EXPRESSION Disclosed herein are methods for decreasing Ataxin 2 mRNA and protein expression. Such methods are useful to treat, prevent, or ameliorate Ataxin 2 associated... |
| 2019/0017046 |
PREPARATION, MEMBER FOR PREPARATION, AND METHODS FOR MANUFACTURING THESE Objects of the present invention are to provide a preparation, which satisfies both a sufficient drug carrying amount and a preferred decomposition rate, and a... |
| 2019/0017045 |
METHODS AND COMPOSITION FOR THE PRODUCTION OF SEQUENCE SPECIFIC
ANTIMICROBIALS A method and composition for the production of sequence specific antimicrobials capable of overcoming inefficient delivery, narrow host range, and potential... |
| 2019/0017044 |
METHOD FOR CONSTRUCTING NEXT-GENERATION SEQUENCING LIBRARY FOR DETECTION
OF LOWFREQUENCY MUTATION AND KIT THEREOF The present invention provides a method for constructing a next-generation sequencing library for detecting low-frequency mutations, and a kit thereof. The... |
| 2019/0017043 |
INTRODUCING METHOD OF L-DIHYDROXYPHENYLALANINE IN TARGET PROTEIN Provided is a method of genetically incorporating an L-dihydroxyphenylalanine in a target protein. |
| 2019/0017042 |
USING NUCLEOSOME INTERACTING PROTEIN DOMAINS TO ENHANCE TARGETED GENOME
MODIFICATION Compositions and methods for using nucleosome interacting protein domains to increase accessibility of programmable DNA modification proteins to target... |
| 2019/0017041 |
LEUCINE BETA ROLL DOMAINS AND USES THEREOF In one aspect, the invention relates to a peptide that forms a calcium-dependent hydrogel using a rationally engineered beta roll peptide. In the absence of... |
| 2019/0017040 |
Compounds and Methods for Stabilizing Thrombin Activity The present invention is directed to compounds useful in stabilizing thrombin activity, thrombin compositions comprising the compounds, methods of using the... |
| 2019/0017039 |
Factor IX Variants with Clotting Activity in Absence of Their Cofactor and
Their Use for Treating Bleeding... The present invention relates to variants of a vitamin K-dependent serine protease of the coagulation cascade, preferably variants of factor IX (F.IX), wherein... |
| 2019/0017038 |
BEVERAGE WITH HIGH SOLID CONTENT COMPRISING BETA-MANNASE The invention relates to compositions for preparing a beverage, the composition comprises a) a coffee liquor or dried coffee extract ranging between 1-40% w/w;... |
| 2019/0017037 |
METHOD FOR USING HEAT-RESISTANT MISMATCH ENDONUCLEASE Provided are a mismatch-specific cleavage reaction using a novel heat-resistant mismatch nuclease, a method for removing errors in a nucleic acid amplification... |
| 2019/0017036 |
POLYPEPTIDE HAVING ENDONUCLEASE ACTIVITY AND METHOD FOR PRODUCING THE SAME A polypeptide includes an amino acid sequence selected from the group consisting of: an amino acid sequence having at least 85% sequence identity to the amino... |
| 2019/0017035 |
METHODS FOR MODULATING CYCLIC NUCLEOTIDE-MEDIATED SIGNALING IN CARDIAC
MYOCYTES AND COMPOSITIONS The invention provides a polypeptide possessing anti-hypertrophic activity in a cardiac myocyte, wherein the polypeptide is a mutant variant derived from... |
| 2019/0017034 |
PROTEIN PROSTHESES FOR MITOCHONDRIAL DISEASES OR CONDITIONS The invention encompasses water-forming NADH and NADPH oxidases and the use of these enzymes to treat mammalian diseases or conditions associated with an... |
| 2019/0017033 |
RECOMBINANT AAV PRODUCTION IN MAMMALIAN CELLS The present invention includes methods and compositions for the production of high titer recombinant Adeno-Associated Virus (rAAV) in a variety of mammalian... |
| 2019/0017032 |
CELL REPROGRAMMING The invention relates to methods and compositions for converting one cell type to another cell type. Specifically, the invention relates to ... |
| 2019/0017031 |
SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME Disclosed herein are methods, compositions, kits, and agents useful for inducing .beta. cell maturation, and isolated populations of SC-.beta. cells for use in... |
| 2019/0017030 |
Immortalized Stem Cells and Method for Producing Same The purpose of the present invention is to provide immortalized stem cells for producing culture supernatant that can be used in the treatment of human... |
| 2019/0017029 |
Generation of Expandable Cardiovascular Progenitor Cells Methods and compositions for expanding cardiovascular progenitor cells are described herein that include use of compositions and culture media that have at... |
| 2019/0017028 |
SYSTEMS AND METHODS FOR CARDIOMYOCYTE PACING Provided herein are systems and methods for cardiomyocyte pacing of cultured cells, including cardiomyoctyes. In particular, provided herein are systems and... |
| 2019/0017027 |
HEMANGIO-COLONY FORMING CELLS Methods of generating and expanding human hemangio-colony forming cells in vitro and methods of expanding and using such cells are disclosed. The methods... |
| 2019/0017026 |
METHOD AND DEVICE FOR CONSERVING VIABLE AND FUNCTIONAL HUMAN
POLYMORPHONUCLEAR NEUTROPHILS A method for keeping leukocytes alive ex vivo or in vitro, comprising maintaining the leukocytes in a medium comprising from 3 to 10 mM of glucose, in hypoxic... |
| 2019/0017025 |
Methods for Inducing the Differentiation of Blood Monocytes into
Functional Dendritic Cells Methods are provided for treating blood monocytes to produce functional antigen presenting dendritic cells. An extracorporeal quantity of a subject's blood is... |
| 2019/0017024 |
Methods for Inducing Migration by Dendritic Cells and An Immune Response Compositions and methods of activating dendritic cells with LMP1 and LMP1-activated dendritic cell based compositions and methods are effective for dendritic... |
| 2019/0017023 |
Augmentation of Cell Therapy Efficacy Including Treatment with Alpha 1,3
Fucosyltransferase Disclosed are methods, compositions of matter, and kits useful for augmentation of cells through modification of cellular membrane properties following ex vivo... |
| 2019/0017022 |
B-CELL CULTIVATION METHOD Herein is reported a method for co-cultivating one or more B-cells comprising the step of incubating the one or more B-cells with EL4-B5 cells, whereby the... |
| 2019/0017021 |
ENHANCED EXPRESSION OF HUMAN OR HUMANIZED IMMUNOGLOBULIN IN NON-HUMAN
TRANSGENIC ANIMALS The present invention describes transgenic animals with human(ized) immunoglobulin loci and transgenes encoding human(ized) Ig.alpha. and/or Ig.beta.... |
| 2019/0017020 |
DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS TO MULTIPOTENT NEURAL
CREST CELLS The present invention relates to the differentiation of human pluripotent cells, including human pluripotent stems cells to produce a self-renewing multipotent... |
| 2019/0017019 |
INDUCTION OF NEURAL PROGENITOR CELLS, OLIGODENDROCYTE PROGENITOR CELLS,
AND OLIGODENDROCYTES BY STEM CELL... A novel method of inducing neural progenitor cells, oligodendrocyte progenitor cells, oligodendrocytes from human iPSCs at an unprecedented efficiency and... |
| 2019/0017018 |
A NEURAL ORGANOID COMPOSITION AND METHODS OF USE The present invention features a neural organoid that recapitulates in vitro most characteristics of the brain (e.g., human), and methods of using this neural... |
| 2019/0017017 |
USE OF VASCULAR CELLS TO CREATE THE CONVENTIONAL OUTFLOW TRACT Provided is a system for modeling the conventional outflow tract, including: a porous scaffold with trabecular meshwork cells attached to one surface and... |
| 2019/0017016 |
SUPPORTED IN VITRO DEVELOPED TISSUE CULTURE AND CULTURING METHODS An elongated or fiber-supported multicellular aggregation of multipotent cells, wherein multipotent cells are arranged in an oblong or longish arrangement with... |
| 2019/0017015 |
Compositions And Methods For Epithelial Stem Cell Expansion And Culture Described are cell culture solutions and systems for epithelial stem cell and organoid cultures, formation of epithelial constructs and uses of the same in... |
| 2019/0017014 |
SUSPENSION CULTURE OF HUMAN EMBRYONIC STEM CELLS This disclosure provides an improved system for culturing human embryonic stem cells. The cells are cultured in suspension so as to maximize the production... |
| 2019/0017013 |
MECHANICAL LYSIS APPARATUS AND METHOD A mechanical lysis method includes (a) spinning a mixing head at a spin rate in a liquid sample, containing cells and beads, such that the mixing head... |
| 2019/0017012 |
FILTER FOR FILTRATION OF NUCLEATED CELLS AND FILTRATION METHOD USING THE
SAME A filtration method for filtration of nucleated cells that includes providing a filter containing at least one of a metal and a metal oxide as a major... |
| 2019/0017011 |
Improvements in and Relating to Biomanufacturing Apparatus Disclosed is biomanufacturing apparatus 1 comprising a housing 20 including top 22 and bottom 24 faces which allow stacking of plural housings, an access door... |
| 2019/0017010 |
System and Method for Transferring Tissue A transfer device designed to extract an amorphous or semi-solid structure, tissue, or construct from supporting media while maintaining the spatial... |
| 2019/0017009 |
FULLY AUTOMATED CONTINUOUS CELL CULTURE SYSTEM The invention provides a full-automatic cell culture system, at least comprising: a control module, a control platform, a dark field microscope for on-line... |
| 2019/0017008 |
Personal Laboratory for Genetic Engineering, Culturing and Analysis of
Microorganisms and Biochemicals A personal laboratory apparatus includes a plurality of life sciences laboratory modules disposed on or in a common housing. The laboratory modules include a... |
| 2019/0017007 |
Model-animal functional-improvement evaluation apparatus and nerve-cell
culturing apparatus Proposed are a functional improvement evaluation apparatus and a nerve cell culture apparatus of model animals capable of performing feedback control, even to... |
| 2019/0017006 |
METHOD AND DEVICE FOR KEEPING SHAPE OF FRAGILE MATERIAL IN LIQUID A method, a device, and an annular member are disclosed for keeping a shape of a fragile material in a liquid in a container. The method includes covering a... |
| 2019/0017005 |
IMPROVEMENTS IN AND RELATING TO CELL HARVESTING APPARATUS Disclosed herein is a cell harvesting instrument suitable for concentrating cells from a source suspension of cells and/or washing said cells, the instrument... |
| 2019/0017004 |
METHODOLOGY FOR PREPARING ETHANOL-REDUCED FERMENTED BEVERAGES The present invention is directed to a generic methodology for preparing wines and other beverages having reduced ethanol content, where said wines or... |
| 2019/0017003 |
Single Stage Winemaking Apparatus and Method A novel fermentation method uses a novel single stage horizontal cylindrical or partial cylindrical fermentor, larger in volume than the target volume of wine,... |
| 2019/0017002 |
Apparatus and Method for Drying Hops An apparatus is provided for drying hops having a gas distribution supply duct, a source of heated gas, and a blower. The gas distribution supply duct has an... |
| 2019/0017001 |
MULTI-COMPARTMENT DETERGENT COMPOSITIONS AND METHODS OF PRODUCTION AND USE
THEREOF The present invention is in the fields of household and industrial cleaning, particularly in applications for cleaning of dishware or laundry. The present... |
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