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Patent # Description
2019/0040422 NOVEL CANDIDA INFANTICOLA STRAIN, MUTANT STRAIN AND TRANSFORMANT STRAIN THEREOF, AND METHOD FOR PRODUCING DIOIC...
The present invention relates to a method for producing dioic acids from a substrate containing hydrocarbons or fatty acids using a Candida infanticola strain,...
2019/0040421 Microbial Production Of Fuel Components From Low-Molecular Weight Gas Mixtures
Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used...
2019/0040420 PROCESS FOR THE MANUFACTURE OF BUTANOL OR ACETONE
A process for the manufacture of butanol, acetone and other renewable chemicals utilizes one or more of by-products of the manufacture of malt whisky, such as...
2019/0040419 PROCESS FOR THE MANUFACTURE OF BUTANOL OR ACETONE
A process for the manufacture of butanol, acetone and/or other renewable chemicals is provided wherein the process utilises one or more of the group comprising...
2019/0040418 Method of Operation of a Syngas Fermentation Process
A process is provided for fermentation of syngas that is effective for reducing conductivity and providing an alcohol STY of about 10 g ethanol/(Lday). The...
2019/0040417 BIOLOGICAL FERMENTATION USING DIHYDROXYACETONE AS A SOURCE OF CARBON
The present invention relates to the use of hydrocarbons derived from natural gas in the fermentative production of biochemicals including biofuels. More...
2019/0040416 Cas Discrimination Using Tuned Guide RNA
CRISPR/Cas Systems are provided where a tuned guide RNA is used to discriminate between two protospacer sequences of same length that differ by one nucleotide.
2019/0040415 CULTURED TRANSGENIC CELL ALLOWING GROWTH OF NOROVIRUS, AND USE THEREOF
An object of the present invention is to solve problems in terms of stagnation of research on norovirus by providing a cultured transgenic cell or a transgenic...
2019/0040414 KIT FOR CONSTRUCTING TRANSPOSON AND USE THEREOF
A kit for constructing a transposon is provided. The kit comprises five plasmids, each of which consists essentially of a gene cassette linked or not linked to...
2019/0040413 MAIZE EVENT DP-032218-9 AND METHODS FOR DETECTION THEREOF
The disclosure provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the...
2019/0040412 PLANTS HAVING ENHANCED TOLERANCE TO INSECT PESTS AND RELATED CONSTRUCTS AND METHODS INVOLVING INSECT TOLERANCE...
The disclosure discloses isolated polynucleotides and polypeptides, and recombinant DNA constructs useful for conferring improved tolerance in plants to insect...
2019/0040411 PESTICIDAL GENES AND METHODS OF USE
Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptide sequences having...
2019/0040410 Methods and Compositions for Plant Pest Control
The present invention provides methods and compositions to improve fungal disease resistance and/or nematode resistance in various crop plants. The present...
2019/0040409 CUCUMBER HYBRID SV3487CP AND PARENTS THEREOF
The invention provides seed and plants of cucumber hybrid SV3487CP and the parent lines thereof. The invention thus relates to the plants, seeds and tissue...
2019/0040407 METHOD FOR PRODUCING PROTEINS FROM A PLANT STRUCTURE
Disclosed is a method for producing proteins of interest from secondary root emergences which appear on the hairy roots of a plant belonging to the...
2019/0040406 PLANT PROMOTER AND 3' UTR FOR TRANSGENE EXPRESSION
This disclosure concerns compositions and methods for promoting transcription and translation of a nucleotide sequence in a plant or plant cell, employing a...
2019/0040405 PLANT GENOME MODIFICATION USING GUIDE RNA/CAS ENDONUCLEASE SYSTEMS AND METHODS OF USE
Compositions and methods are provided for genome modification of a target sequence in the genome of a plant or plant cell. The methods and compositions employ...
2019/0040404 PLANT PROMOTER AND 3' UTR FOR TRANSGENE EXPRESSION
This disclosure concerns compositions and methods for promoting transcription and translation of a nucleotide sequence in a plant or plant cell, employing a...
2019/0040403 TOMATO HYBRID SVTM1082 AND PARENTS THEREOF
The invention provides seed and plants of tomato hybrid SVTM1082 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue...
2019/0040402 TOMATO HYBRID SVTD3418 AND PARENTS THEREOF
The invention provides seed and plants of tomato hybrid SVTD3418 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue...
2019/0040401 Plastid Transformation of Maize
A method is provided for transforming monocotyledonous plants to express DNA sequences of interest from plant cell plastids. The method allows the ...
2019/0040400 YEAST STRAINS AND METHODS FOR CONTROLLING HYDROXYLATION OF RECOMBINANT COLLAGEN
Strains of yeast genetically engineered to produce increased amounts of non-hydroxylated collagen or hydroxylated collagen are described. A chimeric collagen...
2019/0040399 CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and...
2019/0040398 DEADMAN AND PASSCODE MICROBIAL KILL SWITCHES
Provided herein are systems, methods and compositions for rendering cells or the expression of an effector protein sensitive to a predetermined condition. In...
2019/0040397 METHOD FOR PRODUCING DNA VECTORS FROM MOLECULAR BRICKS CONTAINING SEQUENCES OF INTEREST
Disclosed is a method for producing, in one step, "made to measure" double-stranded DNA vectors from molecular bricks including sequences of interest in the...
2019/0040396 Combination Therapy
Methods and compositions for treating cancer, e.g., prostate cancer, using a combination of P-Rex1 or Rac1 inhibitors and VEGF/VEGFR-targeted therapy.
2019/0040395 MODULATORS OF KLK3 ERNA
The present embodiments provide methods, compounds, and compositions useful for inhibiting KLK3 eRNA expression, which may be useful for treating, preventing,...
2019/0040394 TREATMENT OF GLIAL CELL DERIVED NEUROTROPHIC FACTOR (GDNF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE...
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Glial cell derived neurotrophic factor (GDNF),...
2019/0040393 Managing Intercellular Communications
The present invention describes natural, artificial, and/or enhanced methods for controlling intercellular and intracellular communications involving complex...
2019/0040392 TARGETED MRNA FOR IN VIVO APPLICATION
A medicament can include a product for in vivo expression of a protein in a living being. The product can include a first entity, which includes a nucleic acid...
2019/0040391 METHODS AND COMPOSITIONS FOR SELECTION OF FUNCTIONAL OLIGONUCLEOTIDES
The present disclosure describes compositions and methods for rapid selection of both binding and functional oligonucleotides (DNA, RNA, or any natural or...
2019/0040390 POSH INHIBITOR COMPLEX BIOMOLECULES AND AMPHIPHILE MICELLES
The present invention is directed to a composition that includes an amphiphile, its use in a method of preventing and/or treating cancer, and its use in a...
2019/0040389 Post-Transcriptionally Chemically Modified Double Strand RNAs
Described are post transcriptionally chemically modified double strand RNAs (MdsRNAs) having more than 30 base pairs. The MdsRNAs inhibit gene expression in...
2019/0040388 HIPPO AND DYSTROPHIN COMPLEX SIGNALING IN CARDIOMYOCYTE RENEWAL
Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an...
2019/0040387 ANTISENSE NUCLEIC ACIDS
The present invention provides an oligomer which allows exon 45 skipping in the human dystrophin gene.
2019/0040386 MODULATION OF ENHANCER RNA MEDIATED GENE EXPRESSION
Disclosed herein are methods and compounds for inhibiting gene expression by inhibiting enhancer RNAs (eRNAs). Such methods and compounds are useful for...
2019/0040385 DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TARGETING P53 AND METHODS OF USE THEREOF
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders...
2019/0040384 COMPOSITIONS AND METHODS FOR MODULATION OF SMN2 SPLICING IN A SUBJECT
Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and...
2019/0040383 TARGETED RNA EDITING
RNA editing is achieved using oligonucleotide constructs comprising (i) a targeting portion specific for a target nucleic acid sequence to be edited and (ii) a...
2019/0040382 CONTIGUITY PRESERVING TRANSPOSITION
Embodiments provided herein relate to methods and compositions for preparing an immobilized library of barcoded DNA fragments of a target nucleic acid,...
2019/0040381 CLONING AND EXPRESSION SYSTEM FOR T-CELL RECEPTORS
The invention provides a method for rapid cloning of T-cell receptors (TCRs) (e.g., paired .alpha..beta. and .gamma..delta. TCR chains) and B-cell receptors...
2019/0040380 CELL SEEDING SUBSTRATE, METHOD FOR MANUFACTURING THE SAME, AND CELL SHEET SEPARATING METHOD
A cell seeding substrate comprises a base comprising a rotary surface and a photolysis layer formed on the rotary surface of the base. The photolysis layer...
2019/0040379 RECOMBINANT YEAST AND A METHOD FOR PRODUCING ETHANOL USING THE SAME
An acetic acid metabolizing ability of a recombinant yeast strain having xylose-metabolizing ability is to be improved. In such a recombinant yeast strain...
2019/0040378 NOVEL NUCLEIC ACID MOLECULES
The present invention provides novel artificial nucleic acid molecules encoding at least one antigenic peptide or protein and at least one additional sequence...
2019/0040377 ENGINEERED PHENYLALANINE AMMONIA LYASE POLYPEPTIDES
The present invention provides engineered phenylalanine ammonia-lyase (PAL) polypeptides and compositions thereof, as well as polynucleotides encoding the...
2019/0040376 PROTEASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME
The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding...
2019/0040375 ROTHIA SUBTILISINS, S8A FAMILY PROTEASES, AS THERAPEUTIC ENZYMES FOR APPLICATION IN GLUTEN-INTOLERANCE DISORDERS
There are gluten-degrading enzymes found in Rothia species bacteria that are subtilisins that belonging to the S8A family of serine protease family. The Rothia...
2019/0040374 ENZYMES FOR TRIMMING OF GLYCOPROTEINS
The invention concerns fusion proteins, wherein two endoglycosidases are fused, possibly via a linker. The fusion enzymes according to the invention have...
2019/0040373 Engineered Nucleic-Acid Targeting Nucleic Acids
The present disclosure provides engineered cross-type-nucleic-acid targeting nucleic acids and compositions thereof. Nucleic acid sequences encoding the...
2019/0040372 COMPOSITIONS AND METHODS COMPRISING SEQUENCES HAVING MEGANUCLEASE ACTIVITY
Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs,...
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