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Patent # Description
2019/0038754 PHARMACEUTICAL COMPOSITION IN SOLID EXTRUDED FORM
A pharmaceutical composition including an extruded solid and one or more pharmaceuticals or nutraceuticals is provided. The extruded solid includes...
2019/0038753 HIGHLY BRANCHED ALPHA-D-GLUCANS
Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide...
2019/0038752 COMPOSITION COMPRISING DUAL IONIC PH-SENSITIVE COPOLYMER FOR DELIVERING SDF-1 TOPICALLY TO THE BRAIN AND USE...
The present invention relates to a composition for topically delivering SDF-1 into the brain, in which the composition comprises a dual ionic pH-sensitive...
2019/0038751 BRANCHED MULTI-FUNCTIONAL MACROMONOMERS AND USES THEREOF
Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize branched multi-functional macromonomers, which contain a ring-opening...
2019/0038750 TRIPLE ANTIBIOTIC CATIONIC OINTMENT
The present disclosure generally relates to petrolatum-based compositions for suspension of active ingredients and methods for forming stable suspensions of...
2019/0038749 TARGETING MICROBUBBLES
This invention related to manufactured microbubbles, as well as methods of using manufactured microbubbles, for example, in medicinal applications. The...
2019/0038748 DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS
A system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator is provided. In...
2019/0038747 NOVEL ANTI-LAM AND ANTI-PIM6/LAM MONOCLONAL ANTIBODIES FOR DIAGNOSIS AND TREATMENT OF MYCOBACTERIUM...
The present invention broadly provides different compositions, kits, vectors, and methods including monoclonal antibodies directed to epitopes found within...
2019/0038746 RECOMBINANT FUSION PROTEIN FORMULATION
Provided is a liquid formulation that enables the stable storage of recombinant fusion proteins, comprising a recombinant fusion protein, a buffer salt, a...
2019/0038745 METHODS AND COMPOSITIONS FOR TREATMENT OF AMYLOID DEPOSITION DISEASES
Methods and pharmaceutical compositions for treatment of amyloid deposition diseases using chimeric (e.g., mouse-human) antibody are disclosed, including a...
2019/0038744 Combination Therapies and Uses for Treatment of Demyelinating Disorders
Methods and compositions for enhancing one or more of: myelination, re-myelination, oligodendrocyte numbers, or neuroaxonal protection, while ameliorating an...
2019/0038743 USE OF IL-31 MONOCLONAL ANTIBODIES FOR TREATING PRURITUS
Novel compositions derived from antigen-binding sites of immunoglobulins having affinity for IL-31 are provided. The compositions exhibit immunological binding...
2019/0038742 MESENCHYMAL STEM CELLS AS VACCINE ADJUVANTS AND METHODS FOR USING THE SAME
The present invention provides a method of enhancing an immune response to a vaccine by administering a vaccine and a population of isolated allogeneic human...
2019/0038741 MIXED ALLERGEN COMPOSITIONS AND METHODS FOR USING THE SAME
Mixed allergen compositions of two or more different allergens are provided. In some instances, the mixed allergen compositions include: a nut allergen; an...
2019/0038740 MHC Class I Associated Hepatitis B Peptides
The present invention relates to compositions and methods for the prevention, treatment, and diagnosis of Hepatitis B virus (HBV) infection, and discloses...
2019/0038739 RECOMBINANT MODIFIED VACCINIA VIRUS ANKARA (MVA) EQUINE ENCEPHALITIS VIRUS VACCINE
The present invention relates to recombinant modified vaccinia virus Ankara (MVA) and to methods of using the same. In particular, the invention relates to...
2019/0038738 FUNCTIONAL INFLUENZA VIRUS-LIKE PARTICLES (VLPS)
The present invention discloses and claims virus like particles (VLPs) that express and/or contains seasonal influenza virus proteins, avian influenza virus...
2019/0038737 OIL-BASED ADJUVANTS
The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins,...
2019/0038736 STREPTOCOCCUS UBERIS EXTRACT AS AN IMMUNOGENIC AGENT
The present invention relates to an extract of Streptococcus uberis as an immunogenic agent. It also relates to a process for obtaining said agent which...
2019/0038735 VLP-BASED VACCINES FOR TARGETING STAPHYLOCOCCUS AUREUS SECRETED VIRULENCE FACTORS
The present invention is directed to virus-like particles (VLPs) which are engineered to present epitopes from Staphylococcus aureus (SA), preferably...
2019/0038734 METHODS FOR MONITORING AND TREATING CANCER
The present invention provides therapeutic and diagnostic methods and compositions for cancer. The invention provides, inter alia, methods of treating cancer...
2019/0038733 T CELL RECEPTOR-DEFICIENT CHIMERIC ANTIGEN RECEPTOR T-CELLS AND METHODS OF USE THEREOF
The present invention provides compositions comprising a protein expression blocker or PEBL comprising a target-binding molecule and localizing domain, and...
2019/0038732 PROSTATE CANCER VACCINE
Androgen receptor-based vaccines for eliciting an immune reaction in vivo against cells expressing androgen receptor are disclosed. The vaccines are useful in...
2019/0038731 THERAPEUTIC CANCER VACCINE BASED ON STRESS PROTEINS RENDERED IMMUNOGENIC
The invention describes a method for preparing a composition comprising tumour cell stress proteins, said method comprising the following steps: providing...
2019/0038730 ENGINEERED CELLS & METHODS
The present invention relates to engineered cells, engineered chimaeric antigen ligands (CALs), novel uses of multi-specific binding agents for bridging cells,...
2019/0038729 CANCER VACCINES AND METHODS OF TREATMENT USING THE SAME
The invention provides a vaccine comprising a nucleic acid molecule that encodes a dog telomerase reverse transcriptase (dTERT) antigen, as well as methods of...
2019/0038728 PROSTATE-ASSOCIATED ANTIGENS AND VACCINE-BASED IMMUNOTHERAPY REGIMENS
The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c)...
2019/0038727 METHODS FOR COMBINING ADOPTIVE T CELL THERAPY WITH ONCOLYTIC VIRUS ADJUNCT THERAPY
The present invention relates to augmenting the effects of adoptive T cell therapy, such as TVAX Immunotherapy, using adjunct treatment with an oncolytic...
2019/0038726 METHODS FOR TREATING HEADACHE
A headache can be treated more effectively by co-administration of a botulinum toxin and a triptan drug to a patient and/or the effectiveness of a triptan...
2019/0038725 CANCER TREATMENT
The present invention relates to compositions, methods, uses and kits for treating cancer. The present invention relates to methods for minimising the...
2019/0038724 Adeno-Associated Virus-Mediated CRISPR-Cas9 Treatment of Ocular Disease
Disclosed herein are compositions and methods of treating and/or correcting ocular disease in a subject, such as a mammal (e.g., human) eye using an...
2019/0038723 Inhibiting UVB-Irradiation Damage By Targeting Nitric Oxide Synthases (cNOS)
Compositions and methods for inhibition UVB-irradiation damage by targeting constitutive nitric oxide synthases (cNOS), including endothelial NOS (eNOS) and...
2019/0038722 METHOD FOR IMPROVING THE STABILITY OF PURIFIED FACTOR VIII AFTER RECONSTITUTION
The present disclosure relates to a method for increasing the stability of a Factor VIII molecule after purification, lyophilization and reconstitution,...
2019/0038721 GLP-1 DERIVATIVES AND USES THEREOF
The invention relates to GLP-1 analogues and derivatives having a Trp at a position corresponding to position 8 of GLP-1(7-37), and their pharmaceutical use...
2019/0038720 METHODS OF TREATING INFLAMMATORY BOWEL DISEASE AND PARASITE INFECTION
Described herein are methods for the induction of a TH2 immune response and for the treatment and/or prevention of diseases associated with pathological immune...
2019/0038719 COMBINATION PREPARATION INCLUDING A CORTICOSTEROID AND EXOSOMES
The present invention relates to pharmaceutical compositions for a combination therapy with a corticosteroid and exosomes. By means of the combination therapy...
2019/0038718 COMPOSITIONS AND METHODS FOR INHIBITING THE BIOLOGICAL ACTIVITY OF SOLUBLE BIOMOLECULES
The disclosure provides, among other things, compositions that bind to and inhibit the biological activity of soluble biomolecules, as well as pharmaceutical...
2019/0038717 MESENCHYMAL STEM CELL EXPRESSING HEPATOCYTE GROWTH FACTOR, AND USE THEREOF
A recombinant lentiviral vector includes a gene encoding a hepatocyte growth factor (HGF) protein. And a cell that is transfected with the lentivirus produced...
2019/0038716 Use of CD24 Proteins for Treating Leptin-Deficient Conditions
This invention relates to the use of a CD24 protein for treating leptin-deficient conditions, such as lipodystrophy, by increasing the level of circulating...
2019/0038715 PEPTIDES DERIVED FROM ACTIN-LIKE PROTEIN 8 (ACTL8)
The present invention relates to novel peptides derived from Actin-like protein 8 (ACTL8), complexes comprising such peptides bound to recombinant MHC...
2019/0038714 ANTI-INFLAMMATORY COMPOSITION COMPRISING CLAVASPIRIN PEPTIDE ANALOGUE AS EFFECTIVE INGREDIENT
An anti-inflammatory composition includes a clavaspirin peptide analogue as an effective ingredient. CSP-4 peptide as a synthetic peptide produced by...
2019/0038713 COMPOSITIONS COMPRISING TUMOR SUPPRESSOR GENE THERAPY AND IMMUNE CHECKPOINT BLOCKADE FOR THE TREATMENT OF CANCER
Provided herein are methods and compositions for treating cancer in an individual comprising administering to the individual an effective amount of at least...
2019/0038712 METHODS OF TREATMENT USING HEMOPEXIN COMPOSITIONS
The present invention relates generally to a method of purifying proteins. More specifically, the present inventions relates to a method of purifying...
2019/0038711 Medicament For Treating Pulmonary Tuberculosis
A medicament for use in treating tuberculosis, the medicament is a glycoprotein, a mixture of polysaccharide and protein, a polypeptide or a protein.
2019/0038710 MEDICAMENT USED FOR TREATING HYPERTENSION
A medicament for use in treating hypertension. The medicament is a glycoprotein, a mixture of polysaccharide and protein, a polypeptide or a protein.
2019/0038709 A medicament for treating cardiovascular and cerebrovascular diseases
A medicament for use in treating cardiovascular and cerebrovascular diseases, the medicament includes a marine algal glycoprotein.
2019/0038707 GENE THERAPY BASED ANTIDEPRESSANT
Disclosed are methods and compositions for treating a subject having a neurological disorder such as major depressive disorder (MDD). The methods and...
2019/0038706 MEDICAMENT FOR USE IN TREATING GOUT
A medicament for use in treating gout, the medicament being a glycoprotein, a mixture of polysaccharide and protein, a polypeptide or a protein.
2019/0038705 OPTICALLY-BASED STIMULATION OF TARGET CELLS AND MODIFICATIONS THERETO
Stimulation of target cells using light, e.g., in vivo or in vitro, is implemented using a variety of methods and devices. One example involves a vector for...
2019/0038704 EPHA4 Cyclic Peptide Antagonists for Neuroprotection and Neural Repair
The present specification discloses APY cyclic peptides having EphA4 antagonistic activity, pharmaceutical compositions containing such EphA4 antagonists, and...
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