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Patent # Description
2019/0038602 GRANZYME B INHIBITOR FORMULATIONS AND METHODS FOR THE TREATMENT OF BURNS
Formulations for treating burns and burn wound healing comprising a Granzyme B inhibitor and a pharmaceutically acceptable carrier, and methods for treating...
2019/0038601 USE OF TRANS-[TETRACHLOROBIS(1H-INDAZOLE)RUTHENATE(III)] FOR THE TREATMENT OF CANCER
IT-139, sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)], is an intravenously administered small molecule compound. In preclinical anti-tumor and...
2019/0038600 MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DEISEASES
The present invention relates to the use of indolinones of general formula ##STR00001## substituted in the 6 position, wherein R.sub.1 to R.sub.5 and X are ...
2019/0038599 TREATMENT OF AUTOIMMUNE DISEASE IN A PATIENT RECEIVING ADDITIONALLY A BETA-BLOCKER
The present invention relates to methods of treating autoimmune diseases with siponimod in patients receiving additionally a beta-blocker.
2019/0038598 PHARMACEUTICAL COMPOSITION INCLUDING DORZOLAMIDE AND BRIMONIDINE
A pharmaceutical composition includes dorzolamide or a salt thereof and brimonidine or a salt thereof and has a pH of 6.0 or more. The pharmaceutical...
2019/0038597 PREVENTION OF VASCULAR AND CARDIAC FIBROSIS VIA IRE1ALPHA INHIBITION
Provided herein are methods and compositions for treating and/or reducing the risk of developing a condition associated with fibrosis and/or collagen...
2019/0038596 GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF
Provided are compounds generated by conjugation of triptolide with glucose to form glucose-triptolide conjugates, provides compounds with effective...
2019/0038595 Cranberry Extract Useful in the Treatment and Prevention of Urinary Infections
The present invention relates to a concentrated extract of cranberry (Vaccinium macrocarpon), the complex composition of which makes it possible to increase...
2019/0038594 COMPOUNDS AND USES THEREOF
Compounds of Formula I are described ##STR00001## as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric...
2019/0038593 SUSPENSION COMPOSITIONS OF PHYSIOLOGICALLY ACTIVE PHENOLIC COMPOUNDS & METHODS OF MAKING AND USING THE SAME
The present invention is directed to compositions comprising physiologically active phenolic compounds and methods for making and using the same. In particular...
2019/0038592 PACLITAXEL PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL PREPARATION THEREOF, PREPARATION PROCESS AND USE THEREOF
A paclitaxel pharmaceutic composition and a pharmaceutic preparation, a preparation process therefor and use thereof are provided. The paclitaxel composition...
2019/0038591 USE OF A FASTING MIMICKING DIET TO ENHANCE THE EFFICACY OF ANTIESTROGENS IN CANCER
A compound having antiestrogenic activity is used in a method for the treatment of BC or other estrogen-responsive tumors in a human patient, wherein the...
2019/0038590 METHODS OF TREATING HYPERTRIGLYCERIDEMIA
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of...
2019/0038589 COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISEASE
The present invention provides a method and composition for treating a neurodegenerative disease. In particular, the present invention provides a method and...
2019/0038588 NOVEL CLASS OF COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE
The present invention relates to the field of medicine, specifically the field of treatment and prevention of cardiovascular diseases.
2019/0038587 DNA Methylation Landscapes of Post-Traumatic Stress Disorder (PTSD) Susceptibility and Resilience and Novel...
Methods regarding DNA methylation signature of post-traumatic stress disorder (PTSD) in brains of susceptible, resilient animals methylated in response to...
2019/0038586 ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS
The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar...
2019/0038585 FATTY ACID TREATMENT FOR CARDIAC PATIENTS
A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid...
2019/0038584 CARCINOMA DIAGNOSIS AND TREATMENT, BASED ON ODC1 GENOTYPE
The present invention provides methods and kits a) for predicting colorectal cancer patient survival, as well as the survival of patients harboring other...
2019/0038583 METHODS AND COMPOSITIONS FOR INCREASING THE ANAEROBIC WORKING CAPACITY IN TISSUES
Provided are compositions comprising beta-alanylhistidine peptides and/or beta-alanines, and methods for administering these peptides and amino acids. In one...
2019/0038582 COMPOSITIONS AND METHODS FOR INHIBITING KINASE ACTIVITY
The present invention features therapeutic compositions comprising an agent that specifically binds to a PIF pocket of Aurora A kinase and an agent that...
2019/0038581 Treatment of intrahepatic cholestatic diseases
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
2019/0038580 PHENYLKETONE CARBOXYLATE COMPOUNDS AND PHARAMCEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS
The present invention concerns the use of compounds for preventing and/or treating osteoporosis, for stimulating bone formation, for stimulating the...
2019/0038579 SHIKIMATE ANALOGUES AND METHODS OF USE
The present disclosure, in at least certain embodiments, is directed to shikimate (shikimic acid) analogues and compositions thereof, kits which contain the...
2019/0038578 Necrosis Inhibitors
The invention provides amides that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides,...
2019/0038577 SNACKING PRODUCT WITH CAPSAICIN OR ANALOGUE THEREOF
A zero-calorie to near-zero-calorie snacking product that, when consumed, provides a feeling of fullness prior to absorption of energy-providing food, i.e.,...
2019/0038576 Chemosensory Receptor Ligand-Based Therapies
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases,...
2019/0038575 Methods for Protecting Cells During Cancer Therapy
Disclosed herein are compositions including a topical agent that may be used to reduce and/or inhibit the effects of chemotherapy and/or radiotherapy, which...
2019/0038574 NANOPARTICLE TARGETED DRUG DELIVERY TO THE LUNGS USING EXTRA-TESTICULAR SERTOLI CELLS
A method of delivering a compound of interest to the lungs of a subject by the intravenous injection of Sertoli cells loaded with a plurality of chitosan...
2019/0038573 ION CHANNEL ACTIVATORS AND METHODS OF USE
The present invention relates to compositions of ion channel activators and methods of preparation, formulation, and the medical use of these compositions. In...
2019/0038572 COMPOSITION INCLUDING 3-BROMO-4, 5-DIHYDROXYBENZALDEHYDE COMPOUND AS EFFECTIVE COMPONENT FOR PROTECTING AND...
There is provided a composition including a 3-bromo-4,5-dihydroxybenzaldehyde (BDB) for protecting human skin keratinocyte from ultraviolet, in which the BDB...
2019/0038571 Orally Available Small Molecules to Inhibit the Function of the Complement System
The invention relates generally to pterostilbene and a related compound thereof active to inhibit complement at concentrations lower than 1 micromole per liter...
2019/0038570 SUBLINGUAL AND BUCCAL FILM COMPOSITIONS
The present invention relates to products and methods for treatment of various symptoms in a patient, including treatment of pain suffered by a patient. The...
2019/0038569 Multifunctional-reinforced dressing
This invention relates to a surgical or medical dressing which comprises a supporting and reinforcing layer of elastomeric material (as polyethylene...
2019/0038568 DELIVERY SYSTEMS
Disclosed herein are delivery systems including coated and uncoated yarns, yarn precursors, threads, fibers, and other substrates for the constant or...
2019/0038567 ENCAPSULATING AGENT WITH IMPROVED PROPERTIES ADAPTED FOR CELL ENCAPSULATION
The invention is directed to a three-dimensional polymer network for encapsulating a pharmaceutical ingredient, the polymer network comprising (a) at least one...
2019/0038566 BEXAROTENE SOFTGEL CAPSULE AND PREPARATION METHOD THEREOF
The present invention discloses a bexarotene softgel capsule and a preparation method thereof. The bexarotene softgel capsule including: a softgel capsule...
2019/0038565 FABRICATION METHODS FOR NANODELIVERY SYSTEMS FOR LONG TERM CONTROLLED DELIVERY OF ACTIVE PHARMACEUTICAL INGREDIENTS
Embodiments of the present disclosure include devices, and methods of making such devices, for delivery of one or more active agents with short or long...
2019/0038564 Carvedilol Immediate Release Formulation Having Improved Madescent
Disclosed is an immediate-release carvedilol formulation, which is configured such that a coating layer including a polymer, wax, fatty acid and/or fatty acid...
2019/0038563 FILM-FORMING COMPOSITIONS FOR THE FILM-COATING OF SOLID FORMS
The invention relates to a film-forming composition comprising a fluidised hydroxypropyl starch and sorbitol, and to a film-coating method using said...
2019/0038562 FORMULATION HAVING CONTROLLED, DELAYED RELEASE OF ACTIVE INGREDIENT
The present invention relates to novel pharmaceutical formulations which have controlled, delayed release of active ingredient, and to a process for the...
2019/0038561 GASTRO-RESISTANT CONTROLLED RELEASE ORAL DOSAGE FORMS
This disclosure relates to gastro-resistant, controlled release dosage forms comprising Compound (I): ##STR00001## or a pharmaceutically acceptable salt and/or...
2019/0038560 BIOACTIVE COMPOUNDS PROTECTION METHOD AND COMPOSITIONS CONTAINING THE SAME
The present invention relates to means for protecting bioactive materials in mammalian food or feed formulations used to enhance the health status of mammals.
2019/0038559 STABLE DOSAGE FORM OF ETIDRONATE-CYTARABINE CONJUGATE, AND USE THEREOF
The invention relates to the field of medicine and pharmaceuticals and particularly to a novel dosage form of an antitumor preparation, which ensures the...
2019/0038558 PLGA/PEI PARTICLES AND METHODS OF MAKING AND USING THE SAME
Poly(lactic-co-glycolic acid)/polyethylenimine (PLGA/PEI) particles and methods directed to the preparation of PLGA/PEI particles are provided. Methods of...
2019/0038557 MEANS FOR LUNG SPECIFIC DELIVERY
The present invention is related to composition comprising a lipid composition, wherein the lipid composition consists of a cationic lipid of formula (I)...
2019/0038556 FORMULATIONS AND CARRIER SYSTEMS INCLUDING COMPOUND INTERACTIVE DOMAINS
A method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the...
2019/0038555 BICONTINUOUS MICROEMULSIONS AND METHODS OF USE THEREOF
The present disclosure provides bicontinuous microemulsions, and methods of using the bicontinuous microemulsions in the treatment of dry eye.
2019/0038554 SYSTEMS AND METHODS FOR ENHANCED DISTRIBUTION OF A BIOLOGIC AGENT WITHIN THE BRAIN AND SPINAL CORD
Aspects herein relate to systems and methods for delivery of biologic agents to the central nervous system. In various embodiments, a method of administering a...
2019/0038553 DEVICES FOR EVAPORATION AND INHALATION OF ACTIVE AGENTS
There is provided an inhalation device for delivering a deliverable agent in the form of an aerosol or vapour to a user. The device comprises a solid, porous...
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