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Patent # Description
2019/0054162 INFLUENZA VACCINE
The present invention relates to monovalent influenza vaccine formulations and vaccination regimes for immunising against influenza disease, their use in...
2019/0054161 INACTIVATED VACCINE FOR CHIKUNGUNYA VIRUS
The disclosure generally provides a purified inactivated chikungunya virus (CHIKV), methods for producing the purified inactivated CHIKV, immunogenic...
2019/0054160 Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
A method of treating a patient who has prostate cancer includes administering to said patient a composition containing a population of activated T cells that...
2019/0054159 PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT, PROCESS FOR ITS PREPARATION, AND ITS USE
The use of the C-terminal region of one or more phytocystatin(s) for the curative or prophylactic treatment of tumors and/or inhibition of metastases in...
2019/0054158 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AADC DEFICIENCY
The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment,...
2019/0054157 COMPOSITION AND METHOD OF PREPARATION OF PROTEASE MICROPARTICULATE SLOW RELEASE PREPARATION
Compositions containing microparticles loaded with one or protease enzymes and optionally auxiliary therapeutic agents and methods of treating conditions such...
2019/0054156 Stabilized Thrombin
The present invention is directed to compounds, methods for stabilizing thrombin activity with a thrombin binding oligonucleotide and to stabilized thrombin....
2019/0054155 Enzymes And Methods For Cleaving N-Glycans From Glycoproteins
Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly...
2019/0054154 TARGETING OF GLYCOPROTEIN THERAPEUTICS
Methods of making ligand-decorated polymer conjugates of therapeutic glycoproteins are described. Improved targeting of glycoproteins to specific tissues is...
2019/0054153 SIALYLATED GLYCOPROTEIN COMPOSITIONS AND USES THEREOF
The present application relates to sialylated glycoprotein compositions and methods of their use in treating various conditions and disorders.
2019/0054152 Composition and Nutritional Supplement Made Therefrom
The present disclosure is directed to a nutritional supplement composition containing undenatured or denatured Type II collagen in combination with Vitamin A...
2019/0054151 SYNTHETIC PLATELETS
A synthetic platelet including a biocompatible flexible nanoparticle, the nanoparticle having an outer surface and a plurality of site targeted peptides...
2019/0054150 MELANOCORTINS AND METHODS OF USE THEREOF
In some aspects, the present disclosure provides compositions and methods for treating disease, e.g., inflammatory disease. Compositions herein comprise one or...
2019/0054148 NOVEL CELL MEMBRANE-PERMEATING PEPTIDE
The present invention addresses to provide a novel membrane permeability-improving agent which can be applied to high molecular drugs. More specifically, the...
2019/0054147 COMPOSITIONS AND METHODS FOR TREATMENT OF PEDIATRIC PAIN
Disclosed are methods of treating pain in a mammal, which may include the step of administering human growth hormone to a mammal in need thereof. The pain...
2019/0054146 PREVENTION OF HYPOGLYCEMIA IN DIABETES MELLITUS TYPE 2 PATIENTS
A method for the prevention of hypoglycaemia in diabetes mellitus type 2 comprising administering (a) desPro.sup.36Exendin-4(1-39)-Lys.sub.6-NH.sub.2 or/and...
2019/0054145 SYNERGISTIC TUMOR TREATMENT WITH IL-2, AN INTEGRIN-BINDING-FC FUSION PROTEIN, AND A CANCER VACCINE
The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a...
2019/0054144 PHARMACEUTICAL COMPOSITION FOR TREATING ISCHEMIC STROKE AND METHOD THEREOF
Disclosed is a pharmaceutical composition for treating ischemic stroke, comprising an effective amount of human mesenchymal stem cells, human serum albumin,...
2019/0054143 ANTI-SSX-2 T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE
The invention provides an isolated or purified T cell receptor (TCR) having antigenic specificity for synovial sarcoma X Breakpoint (SSX)-2. The invention...
2019/0054142 ALPHA-1-MICROGLOBULIN FOR USE IN THE PROTECTION OF KIDNEYS IN CONNECTION WITH USE OF CONTRAST MEDIA
This invention relates to an alpha-1-microglobulin for use in prevention of contras medium nephropathy.
2019/0054141 MOLECULAR MARKER FOR CANCER STEM CELL
A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer...
2019/0054140 BACTERICIDAL PEPTIDES AND USES THEREOF
Antimicrobial compositions having bactericidal activity are described. Also described is a method of treating bacterial infections using compositions...
2019/0054139 COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM
A novel class of embryo derived peptides are described (Preimplantation factor) that were generated synthetically and were tested on peripheral blood immune...
2019/0054138 METHODS AND COMPOSITIONS FOR MODULATING HGF/MET
The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating binding of HGF .beta. chain to c-met.
2019/0054137 PEPTIDES AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES
The present disclosure provides pharmaceutical compositions comprising rationally designed peptide analogs of the p65-TAD binding region of GILZ to selectively...
2019/0054136 Dietary Supplement for the Treatment of Acid Reflux and Gastro-Oesophageal Reflux Disease (GORD/GERD)
Use of dietary fibre material extracted from sugar cane in the manufacture of a food product that is formulated to ameliorate the effects of acid reflux and...
2019/0054135 PLANT OR MICROORGANISM-DERIVED CAROTENOID-OXYGEN COPOLYMER COMPOSITIONS, METHODS OF IDENTIFYING, QUANTIFYING...
The present invention relates to carotenoid-oxygen copolymers, compositions, methods of identifying and quantifying carotenoid-oxygen copolymers in food and...
2019/0054134 WHOLE GREEN COFFEE BEAN PRODUCTS AND METHODS OF PRODUCTION AND USE FOR PREVENTING OR TREATING OBESITY AND DIABETES
Disclosed are novel processing methods for green coffee beans that result in novel green coffee bean products, including products that incorporate whole green...
2019/0054133 METHOD FOR INCREASING EXPRESSIONS OF CLOCK GENE, ARNTL GENE, AND/OR PER2 GENE BY USING MOMORDICA CHARANTIA EXTRACT
A method for increasing the expressions of CLOCK, ARNTL and/or PER2 genes is provided, wherein the method comprises administering to a subject in need an...
2019/0054132 CHINESE MEDICINE COMPOSITION FOR TREATING LEUKEMIA BONE MARROW TRANSPLANT FAILURE COMPLICATED BY BRAIN STEM...
A Chinese medicine composition for treating leukemia bone marrow transplant failure complicated by brain stem stroke after chemotherapy, wherein the...
2019/0054131 REPLICATION COMPETENT ATTENUATED VACCINIA VIRUSES WITH DELETION OF THYMIDINE KINASE WITH AND WITHOUT THE...
The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of poxviruses,...
2019/0054130 TREATMENT METHODS USING ADENOVIRUS
The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor by inhibiting, decreasing, or reducing neo-vascularization or...
2019/0054129 REDUCING CONJUGATIVE PLASMIDS IN BACTERIA
The present invention provides methods and compositions to reduce prevalence of plasmids in microbial colonies, including infections, and includes therapeutic...
2019/0054128 VAGINAL PREPARATIONS FOR MAINTAINING AND/OR RESTORING HEALTHY FEMALE MICROBIOTA
The present invention is directed to the direct application of beneficial or probiotic bacteria to the vaginal niche for maintenance of a healthy vaginal...
2019/0054127 ANTIVIRAL AGENT AND ANTIVIRAL FOOD
Provided are an antiviral agent and an antiviral food as novel methods for utilizing a Euglena-derived material. The antiviral agent and antiviral food, both...
2019/0054126 COMPOSITIONS AND METHODS FOR ENHANCING CANCER RADIOTHERAPY
A nutritional supplement containing fish oil and selenium has been identified that potentiates radiotherapy of tumors in a synergistic fashion. Cotherapy with...
2019/0054125 hUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS
This invention encompasses methods, pharmaceutical compositions, and kits for modulating (e.g. reducing) the production of pro-inflammatory mediators involved...
2019/0054124 CELL POPULATION SEEDING IN DERMAL MATRICES FOR ENDOCRINE DISORDER MANAGEMENT
A method of delivering a cell derived factors to a subject is described, which includes implanting a matrix material into an intracutaneous location in the...
2019/0054123 CELL SHEET COMPOSITION INCLUDING MESENCHYMAL STEM CELLS, AND METHOD FOR HEALING LUMINAL ORGAN USING SAME
The present invention addresses the problem of providing a cell sheet composition for healing or preventing discharge from a wounded region of a luminal organ....
2019/0054122 INTRACELLULAR GENOMIC TRANSPLANT AND METHODS OF THERAPY
Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using...
2019/0054121 COMPOSITIONS AND METHODS FOR DELIVERY OF IMMUNE CELLS TO TREAT UN-RESECTABLE OR NON-RESECTED TUMOR CELLS AND...
The present disclosure provides compositions and methods for the delivery of immune cells to treat un-resectable or non-resected tumor cells and tumor relapse....
2019/0054120 COMPOSITIONS AND METHODS FOR ISOLATING AND ENRICHING IGM-PRODUCING CELLS AND USES THEREOF
The technology described herein relates, at least in part, to compositions comprising and methods for isolating and enriching natural IgM-producing phagocytic...
2019/0054119 MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS
The disclosed methods are generally directed to preventing, treating, suppressing, controlling or otherwise mitigating side effects of T-cell therapy, the...
2019/0054118 Small Molecule Agonists and Antagonists of NR2F6 Activity in Animals
The present technology is directed to modulators of nuclear receptor activity, specifically to the modulation of NR2F6 activity and NR2F6 utilizing compounds,...
2019/0054117 DIMERIZATION SWITCHES AND USES THEREOF
The present invention provides gene editing systems comprising gene editing dimerization switches comprising a first and second gene editing switch domain that...
2019/0054116 TUMOR-ASSOCIATED DENDRITIC CELL PREPARATIONS AND USES THEREOF
The present application relates to tumor-associated dendritic cell (TADC) preparations and their use in treatment of tumor metastasis.
2019/0054115 COMPOSITIONS AND METHODS FOR INCREASING IRON INTAKE IN A MAMMAL
Compositions containing iron, buffering agent and denatured protein have been prepared that are capable of increasing serum iron in a subject. For example,...
2019/0054114 EMULSION AND METHOD FOR THE MANUFACTURE THEREOF
The invention relates to an emulsion containing a mixture of an aqueous phase and an oil phase, wherein the aqueous phase comprises seawater, a viscosifier,...
2019/0054113 METHODS FOR TREATING MUSCULAR DYSTROPHY
The present disclosure provides, among other things, improved compositions and methods for treating muscular dystrophy. For example, the disclosure provides...
2019/0054112 POLYNUCLEOTIDE FORMULATIONS FOR USE IN THE TREATMENT OF RENAL DISEASES
The present invention relates to compositions and methods for the preparation, manufacture and therapeutic use of renal polynucleotides.
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