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Patent # Description
2019/0054060 COMPOSITIONS AND METHODS FOR TREATMENT OF INFLUENZA VIRUS
Therapy for influenza using a combination of a neuraminidase inhibitor, a macrolide antibiotic, and a non-steroidal anti-inflammatory drug has been found to...
2019/0054059 PARENTERAL FORMULATIONS OF MACROLIDE ANTIBIOTICS
Described herein are pharmaceutical compositions adapted for the parenteral administration of macrolide antibiotics, such as triazole-containing and...
2019/0054058 Methods of Treating or Preventing Bone Loss
The present disclosure provides compositions comprising eicosapentaenoic acid or a derivative thereof, and methods of treating or preventing bone loss using same.
2019/0054057 IMMUNE BOOSTING DIETARY COMPOUNDS FOR DISEASE CONTROL AND PREVENTION
Provided herein are small-molecule compounds and combinations thereof that enhance the synthesis of animal endogenous genus host defense peptides, which...
2019/0054056 PRECURSOR COMPOUNDS FOR PROVIDING RETINOIDS OF THE VATAMIN A5 PATHWAY AND USES THEREOF
The invention relates to the field of retinoid X receptor (RXR) signaling and a novel vitamin A pathway called Vitamin A5 pathway. Compounds which are useful...
2019/0054054 Methods reducing or preventing oxidation of high density lipoprotein (HDL)
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of...
2019/0054053 FATTY-ACID BASED PARTICLES
The present invention is directed toward fatty acid-based particles, and methods of making such particles. The particles can be associated with an additional,...
2019/0054052 ALLEVIATING OXIDATIVE STRESS DISORDERS WITH PUFA DERIVATIVES
Some aspects of the invention provide for essential fatty acids which are substituted in specific positions to slow down oxidative damage by Reactive Oxygen...
2019/0054051 DOPA Formulations for Treatments of Parkinson's Disease
The present disclosure provides compositions and methods for preventing and treating dyskinesia, such as drug-induced dyskinesia in patients of Parkinson's...
2019/0054050 BACLOFEN FORMULATIONS AND METHODS FOR MAKING SAME
Methods for preparing sterilized baclofen solutions include adjusting the pH to below a desired pH, and steam sterilizing the solution with adjusted pH, which...
2019/0054049 ACTIVATION OF AMP-PROTEIN ACTIVATED KINASE BY OXALOACETATE COMPOUNDS
The present invention relates to oxaloacetate compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds,...
2019/0054048 ANTIBACTERIAL AND ANTIFUNGAL COMPOUNDS
The present application provides that synthetic retinoid compounds are useful in methods of treating bacterial infections, such as a bacterial infection caused...
2019/0054047 TREATMENT OF MALIGNANT ADRENOCORTICAL TUMOR WITH NICLOSAMIDE AND OTHER COMPOUNDS
Disclosed herein are methods of treating a malignant adrenocortical tumor, including a locally advanced and metastatic adrenocortical carcinoma. In some...
2019/0054046 PHARMACEUTICAL COMPOSITION FOR PREVENTION OF DIET INDUCED OBESITY
The present invention relates to a pharmaceutical composition/formulation for the prevention of diet induced obesity. More particularly, the invention relates...
2019/0054045 METHODS AND COMPOSITIONS FOR TREATING SKIN CONDITIONS
The disclosure provides methods and compositions for treating skin conditions. In particular, the disclosure provides compositions comprising metformin either...
2019/0054044 ORAL DOSAGE FORM OF BOTH CLOMIPHENE ISOMERS AND METHOD OF USING SAME TO TREAT SECONDARY HYPOGONADISM AND...
The present invention relates to a pharmaceutical oral dosage form comprising both (A) trans-clomiphene or a pharmaceutically acceptable salt thereof and (B)...
2019/0054043 OXPRENOLOL COMPOSITIONS FOR TREATING CANCER
The present invention relates to compositions of S-enantiomer enriched oxprenolol and their use in treating cancer and treating or preventing, in cancer...
2019/0054042 BINGE BEHAVIOR REGULATORS
Methods and compositions utilizing 2-aminoindan derivatives collectively represented by Formula I as described and defined in the specification for regulating...
2019/0054041 USE OF NOOTKATONE
Disclosed is a use of a nootkatone in the preparation of medicines for preventing and/or treating depression. The nootkatone has a significant efficacy which...
2019/0054040 Identification of Stabilizers of Multimeric Proteins
Disclosed herein are compounds and compositions thereof which find use in increasing stability of TTR tetramers reducing its tendency to misfold and form...
2019/0054039 THERAPEUTIC REGIMENS AND METHODS FOR IMPROVING VISUAL FUNCTION IN VISUAL DISORDERS ASSOCIATED WITH AN...
Disclosed herein are therapeutic regimens for improving visual function in Retinitis Pigmentosa and other visual disorders associated with an endogenous...
2019/0054038 NITRIC OXIDE GENERATING FORMULATIONS AND KITS
An example of a nitric oxide generating formulation includes an S-nitrosothiol (RSNO) powder, a salt, and an additive. The additive is to control or accelerate...
2019/0054037 COMPOSITIONS AND METHODS FOR TREATING MUSCULAR DYSTROPHY AND OTHER DISORDERS
The present invention provides compositions and methods of their use in treating muscular dystrophy and other disorders.
2019/0054036 ELECTROSPUN FIBERS HAVING A PHARMACEUTICAL AND METHODS OF MAKING AND USING THE SAME
A fiber may comprise an electrospun polymer and a pharmaceutical. The pharmaceutical may be dispersed within the electrospun polymer, and may have the form of...
2019/0054035 SELF-ASSEMBLED PEPTIDE NANOFIBERS AND USE THEREOF FOR TARGETED DRUG DELIVERY
Provided are peptide-based nanostructures, as well as diagnostic and therapeutic methods using same.
2019/0054034 Drug Delivery System and Method for Targeting Cancer Stem Cells
Systems and methods for targeting specific cancer cell subpopulations present in tumor tissue are described. A system can include a first component for...
2019/0054033 USE OF POLYMERIC EXCIPIENTS FOR LYOPHILIZATION OR FREEZING OF PARTICLES
Provided herein are use of polymeric excipients, specifically polyvinyl alcohols, optionally in conjunction with sugars, as cryoprotectants to prevent...
2019/0054032 PHARMACEUTICAL COMPOSITION COMPRISIONG BILE SALT, PREPARATION METHOD THEREOF, AND APPLICATION OF SAME
There are provided a pharmaceutical composition, a preparation method thereof, and an application of same. The pharmaceutical composition includes an active...
2019/0054031 OVERDOSE PROTECTION AND ABUSE DETERRENT IMMEDIATE RELEASE DRUG FORMULATION
The presently disclosed subject matter provides a solid immediate release pharmaceutical multi-particulate dosage form containing at least two different...
2019/0054030 METHOD USING ENTERIC-COATED ETIDRONATE FOR TREATING CALCIFICATION, HYPERCALCAEMIA, AND CALCINOSIS OF THE BRAIN...
Among other things, compositions, kits, and methods for epilepsy therapy using a process for treating calcinosis manifested in Neurocysticercosis, Tuberous...
2019/0054029 PHARMACEUTICAL COMPOSITION PARTICLES, ORALLY DISINTEGRATING PREPARATION INCLUDING SAME, AND METHOD FOR...
Provided are pharmaceutical composition particles which are capable of achieving both of masking of an unpalatable taste and improvement in dissolution...
2019/0054028 SUSTAINED-RELEASE FORMULATIONS OF COLCHICINE AND METHODS OF USING SAME
Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an...
2019/0054027 Solid Pharmaceutical Formulations for Treating Endometriosis, Uterine Fibroids, Polycystic Ovary Syndrome or...
The present disclosure relates to pharmaceutical compositions comprising a gonadotropin-releasing hormone (GnRH) antagonist and methods of preparing and using...
2019/0054026 SOLID PREPARATION
The present invention provides a solid preparation wherein variation in weight is suppressed, a solid preparation wherein the active ingredient is stabilized,...
2019/0054025 METHOD FOR PREPARING PHARMACEUTICAL COMPOSITION COMPRISING QUINOLINE DERIVATIVE OR SALT THEREOF
The present invention provides a method for preparing a pharmaceutical composition containing a quinoline derivative or a salt thereof. Specifically, the...
2019/0054024 Solid Dosage Forms
A solid pharmaceutical dosage form having drug-loaded particles and methods of making.
2019/0054023 SUSTAINED RELEASE CYCLOSPORINE-LOADED MICROPARTICLES
A controlled release pharmaceutical formulation is provided, comprising cyclosporine-loaded microparticles of a bioresorbable polymer comprising ...
2019/0054022 FORMULATIONS OF SITE-SPECIFIC, MICROPARTICULATE COMPOSITIONS AND THEIR USE TO IMPROVE OUTCOME AFTER ANEURSYMAL...
The described invention provides site-specific sustained release microparticulate formulations containing a therapeutic amount of an L-type voltage gated...
2019/0054021 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL
The instant invention is drawn to a hepatocyte targeted composition comprising insulin associated with a lipid construct comprising an amphipathic lipid and an...
2019/0054020 ANESTHETIC CHEWING GUM
The anesthetic chewing gum includes lidocaine HCL and prilocaine HCL as the anesthetic ingredients, as well as a chewing gum base. The anesthetic chewing gum...
2019/0054019 METHODS FOR USING REGULATORS FOR INCREASING THE EXPRESSION OR ACTIVATION OF P53 AND/OR REGULATORS FOR REDUCING...
The invention relates to a regulator for increasing the expression of the p53 protein in hepatocyte cells and/or a regulator for reducing or inhibiting the...
2019/0054018 NASOLACRIMAL DRAINGAGE SYSTEM IMPLANTS FOR DRUG THERAPY
An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed...
2019/0054017 DRUG DELIVERY METHODS, STRUCTURES, AND COMPOSITIONS FOR NASOLACRIMAL SYSTEM
An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of...
2019/0054016 NASAL DELIVERY
A nasal delivery device for and method of delivering a substance, preferably comprising oxytocin, non-peptide agonists thereof and antagonists thereof,...
2019/0054015 TEMPERATURE SENSITIVE HYDROGEL COMPOSITION INCLUDING NUCLEIC ACID AND CHITOSAN
The present invention provides a temperature sensitive hydrogel composition including a nucleic acid and chitosan. Since the hydrogel has excellent...
2019/0054014 METHODS AND COMPOSITIONS FOR ENHANCING THE VIABILITY OF MICRONEEDLE PORES
Described herein is a method of transdermally administering one or more pharmaceutically active agents to a mammal. The method comprises administering one or...
2019/0054013 LOW FREQUENCY GLATIRAMER ACETATE THERAPY
A method of alleviating a symptom of relapsing-remitting multiple sclerosis in a human patient suffering from relapsing-remitting multiple sclerosis or a...
2019/0054012 INJECTABLE PASTES BASED ON OPPOSITELY CHARGED POLYMER/CALCIUM PHOSPHATE NANOPARTICLES
Provided herein are polymer-stabilized CaP nanoparticle formulations and related methods of manufacture. In certain embodiments, the methods reliably and...
2019/0054011 COMPOSITIONS FOR TREATING INFECTIONS
The present invention relates to compositions and in particular to compositions for treating a skin or mucosal membrane infection.
2019/0054010 FORMULATION AND AEROSOL CANISTERS, INHALERS, AND THE LIKE CONTAINING THE FORMULATION
Compositions containing tiotropium or a pharmaceutically acceptable salt or solvate thereof, citric acid or a salt thereof, glycerol, ethanol, and a...
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