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Patent # Description
2019/0076501 OXYTOCIN IMPROVES TREATMENT OF OBSTRUCTIVE SLEEP APNEA
The present disclosure provides methods for treating obstructive sleep apnea (OSA) and OSA induced cardiorespiratory diseases. The disclosure provides, inter...
2019/0076500 COMBINATIONS COMPRISING FXR AGONISTS
The invention provides pharmaceutical compositions comprising a farnesoid X receptor (FXR) agonist or caspase inhibitor and another therapeutic agent, e.g....
2019/0076499 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEARING LOSS COMPRISING OAT EXTRACT AS AN ACTIVE INGREDIENT
A method for preventing or treating hearing loss includes administering a composition comprising an oat extract to a subject. The method may use avenanthramide...
2019/0076498 FEIJOA FRUIT EXTRACT
The invention relates to a feijoa fruit extract. In particular the invention relates to therapeutic uses of a feijoa fruit extract, processes for preparing the...
2019/0076497 ORAL AND INTESTINAL HEALTH PRODUCTS
In various implementations, one or more compositions may be provided to improve or maintain oral and/or intestinal health. For example, a dental powder,...
2019/0076496 POLYSACCHARIDE DIGESTION INHIBITOR
An object of the present invention is to provide a novel polysaccharide digestion inhibitor of plant origin. A polysaccharide digestion inhibitor comprising an...
2019/0076495 SYNERGISTIC COMBINATIONS OF CAFFEINE, GINKGO BILOBA AND BETA-PHENYLETHYLAMINE
The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, ginkgo biloba, and .beta.-phenylethylamine (PEA) or...
2019/0076494 LUNG CANCER THERAPY WITH A PARVOVIRUS
Described is the use of parvovirus for the treatment of lung cancer. The parvovirus is based on parvovirus HI (H-1PV) or a related rodent parvovirus selected...
2019/0076493 ONCOLYTIC ADENOVIRUS ENCODING A B7 PROTEIN OR ACTIVE FRAGMENT
The present disclosure provides a replication competent oncolytic adenovirus with selectivity for cancer cells, wherein the adenovirus comprises a transgene...
2019/0076492 IMMUNITY-INDUCING AGENT
The present invention relates to a novel immunity-inducing agent for treatment and/or prevention of cancer. Specifically, the present invention relates to an...
2019/0076491 METHODS OF TREATING SUBSTANCE ABUSE RELATED DISEASES OR DISORDERS
Compositions and methods for treating a subject for a substance-abuse related disease or disorder are disclosed. The substance-abuse related disease or...
2019/0076490 SYNBIOTICS COMBINATION FOR BRAIN IMPROVEMENT
The invention relates to nutritional compositions with Bifidobacterium breve and non-digestible oligosaccharides for use infants or toddlers for use in...
2019/0076489 GENE EXPRESSION SYSTEM FOR PROBIOTIC MICROORGANISMS
Provided herein are recombinant microorganisms that express a subject polypeptide. Microorganisms can comprise an expression construct comprising a flagellin...
2019/0076488 FEED ADDITIVE COMPOSITION
A feed additive composition comprising a direct fed microbial in combination with a protease, a xylanase, an amylase and a phytase, and a method for improving...
2019/0076487 ANAEROPLASMATALES FOR USE IN THE TREATMENT OR PREVENTION OF AN INFLAMMATORY DISORDER OF THE DIGESTIVE SYSTEM
A composition including one or more bacteria of the order Anaeroplasmatales for use as a medicament in methods of treatment or prevention of an inflammatory...
2019/0076486 USE OF GRAM NEGATIVE SPECIES TO TREAT ATOPIC DERMATITIS
Pharmaceutical compositions are disclosed that includes a therapeutically effective amount of a purified viable gram negative bacteria and a pharmaceutically...
2019/0076485 ANTI-OBESITY MICROBIOTA COMPOSITIONS AND PREPARATION METHODS AND USES THEREOF
The present invention relates to microbiota compositions and their preparation methods and uses. Particularly, the present invention provides microbiota...
2019/0076484 Biomarkers For Early Determination Of Severity Of Influenza Related Disease
The present invention relates to the use of at least one biomarker for predicting the severity of a disease caused by the infection of an individual with an...
2019/0076483 HONEYBEE POLLEN COMPOSITION
The present invention relates to a honeybee pollen composition, and more particularly to a honeybee pollen composition prepared by mixing solidified honeybee...
2019/0076482 ENHANCED ORGANOID FORMATION AND INTESTINAL STEM CELL RENEWAL
High mobility group A1 (Hmga1) chromatin remodeling proteins are enriched in intestinal stem cells (ISCs), although their function in this setting was unknown....
2019/0076481 Method to amplify cardiac stem cells in vitro and in vivo
Compositions comprising stem cells delivered into infarcted myocardium by endocardial injection engraft and differentiate into myocytes, endothelial cells, and...
2019/0076480 THERAPY USING CARDIAC STEM CELLS AND MESENCHYMAL STEM CELLS
Compositions comprising stem cells delivered into infarcted myocardium by endocardial injection, engraft and differentiate into myocytes, endothelial cells,...
2019/0076479 ADIPOSE TISSUE-DERIVED STEM CELLS FROM TRANSGENIC PORCINE ANIMALS FOR HUMAN USE
The invention provides for compositions and methods for making and using adipose-derived stem cells for treating non-human mammals for various medical...
2019/0076478 CANINE BLOOD PLATELET PREPARATIONS
The present disclosure provides dry and liquid compositions that include canine platelets and/or canine platelet-derived substances in dried form or rehydrated...
2019/0076477 NOVEL IMMUNOTHERAPY AGAINST NEURONAL AND BRAIN TUMORS
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the...
2019/0076476 NOVEL IMMUNOTHERAPY AGAINST NEURONAL AND BRAIN TUMORS
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the...
2019/0076475 MATERIALS AND METHODS FOR INCREASING IMMUNE RESPONSES
Provided herein are materials and methods for treating a cancer and/or an infection in a mammal. One or more mitochondrial protein uncoupling protein 2 (UCP2)...
2019/0076474 Induction of Regulatory B Cells for the Treatment of Immune Mediated Diseases
The present invention contemplates that complement receptor 1 and 2 may play a role in the induction of regulatory B cells under inflammatory conditions that...
2019/0076473 AUTOLOGOUS AND ALLOGENIC MACROPHAGES AND MONOCYTES FOR USE IN THERAPEUTIC METHODS
Provided herein are innate immune cells for use in therapeutic methods. Also described herein are pharmaceutical compositions comprising innate immune cells...
2019/0076472 HYPERAMMONEMIA THERAPY FOR CHILDREN SUFFERING FROM UREA CYCLE DISORDERS
A method and composition for treating or preventing the progression of hyperammonemia caused by a Urea Cycle Disorder, the method comprising administration of...
2019/0076471 DIETARY SUPPLEMENTS, ADDITIVES, AND DRENCH FOR LIVESTOCK
A first livestock feed additive comprises calcium, phosphorus, sodium chloride, potassium, sulfur, magnesium, manganese, zinc, iron, copper, selenium, vitamin...
2019/0076470 ANTI-HEMORRHAGING COMPOSITIONS
Compositions comprising a citrate salt and a calcium carbonate-containing material, articles-of-manufacturing and kits comprising same and uses thereof for...
2019/0076469 TOPICALLY ADMINISTERED STRONTIUM-CONTAINING COMPLEXES FOR TREATING PAIN, PRURITIS AND INFLAMMATION
Therapeutically-active compositions that combine strontium with at least one additional molecules that increase the overall therapeutic potency of the...
2019/0076467 ANTIVIRAL CONJUGATES OF POLYANIONIC POLYMER AND ANTIVIRAL DRUG
A compound is provided, which comprise an anionic polymer carrier conjugated to an antiviral drug via a biodegradable linker. This compound is particularly...
2019/0076466 REDUCED SODIUM POLOXAMER-188 FORMULATIONS AND METHODS FOR USE
Provided is a sterile, injectable solution comprising: poloxamer 188 and water for injection, wherein the sterile, injectable solution is reduced in sodium...
2019/0076465 MODULATORS OF SMAD7 EXPRESSION
The present embodiments provide methods, compounds, and compositions useful for inhibiting SMAD7 expression, which may be useful for treating, preventing, or...
2019/0076464 CYTIDINE DEAMINASE INHIBITORS FOR THE TREATMENT OF PANCREATIC CANCER
The present invention relates to methods and pharmaceutical compositions for use in the treatment of pancreatic cancer in a subject in need thereof. The...
2019/0076463 NOVEL RNA CONSTRUCT AND METHODS OF USE THEREOF FOR ENHANCING THE THERAPEUTIC EFFECTS OF CYTOTOXIC CELLS AND...
The present invention comprises Rig I agonists for enhancing the effects of cytotoxic cells and stem Cells. The Rig I agonists can be used in vivo as small...
2019/0076462 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF
Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino...
2019/0076461 MATERIALS AND METHODS FOR TREATING HYPOXIC CONDITIONS
This document provides materials and methods for treating hypoxic conditions (e.g., tissue ischemia). Compositions containing a potato polysaccharide...
2019/0076460 An mRNA cancer vaccine encoding human GM-CSF fused to multiple tandem epitopes
The present invention provides an mRNA cancer vaccine encoding human GM-CSF fused to multiple tandem epitopes. pVec-GM-CSF-hTes encoding human GM-CSF fused to...
2019/0076459 ENHANCING PLASMIN ACTIVITY TO PREVENT SOFT TISSUE CALCIFICATION
A method for reducing or substantially preventing soft tissue calcification is provided. The method includes administering at least one of a downregulator of...
2019/0076458 METHODS AND COMPOSITIONS FOR ATTENUATING GENE EXPRESSION MODULATING ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSES
Provided herein are methods and related compositions for administering viral transfer vectors and antigen-presenting cell targeted immunosuppressants.
2019/0076457 NANOPARTICLE TO TARGET CANCER
A construct, or a pharmaceutically acceptable salt thereof, comprising: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene...
2019/0076456 COMPOSITIONS AND METHODS FOR LIVER DISEASES
Embodiments of the present invention disclose a composition comprising nicotinamide adenine dinucleotide (NAD+), wherein the NAD+ is in an amount effective for...
2019/0076455 TREATMENT OF LEUKEMIA VIA THE ADMINISTRATION OF DOT1L INHIBITOR PINOMETOSTAT
The present invention relates to a method for the treatment of leukemia and the induction of leukemic blast cell maturation or differentiation via the...
2019/0076454 CALCIUM GLUCONATE SOLUTIONS IN FLEXIBLE CONTAINERS
A terminally sterilized aqueous calcium gluconate solution comprising 1 to 15 wt. % calcium gluconate and from 1 to 19 wt. parts of calcium saccharate per 100...
2019/0076453 TOPICAL WASH COMPOSITION FOR USE IN ACNE PATIENTS
Wash compositions for topical application are described. The compositions can be stable and well tolerated. Also described, are methods of using such...
2019/0076452 THERAPEUTIC COMBINATIONS FOR TREATING NEOPLASIA
The invention features doxorubicin or Doxil in combination with a checkpoint inhibitor (e.g., an anti-CTLA-4 antibody, anti-PD-1 antibody, an anti-PD-L1...
2019/0076451 Antibiotic Kit and Composition and Uses Thereof
The present invention relates to a therapeutic kit to provide a safe and effective dosage of an antibiotic agent, including an aerosol packaging assembly...
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