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Patent # Description
2019/0078124 ENGINEERED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
The present disclosure provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells...
2019/0078123 Process for Enzymatic Production of Triglycerides
An enzymatic process for producing fatty acid triglycerides using a lipase catalyst system that includes a mixture of a supported lipase catalyst and an...
2019/0078122 METHOD FOR MASS-PRODUCING VINIFERIN USING STEVIOSIDE FROM CELL CULTURE OF GRAPEVINE TISSUE
The present invention relates to a method for mass-production of viniferin using stevioside from cell culture of grape tree tissue. Viniferin is known to be...
2019/0078121 PROCESSES AND SYSTEMS FOR METABOLITE PRODUCTION USING HYDROGEN RICH C1-CONTAINING SUBSTRATES
The invention is directed to a process for producing one or more fermentation product in a multi-stage process including an inoculation reactor and at least...
2019/0078120 VARIANT TYPE TETRAPRENYL-B-CURCUMENE CYCLASE AND METHOD FOR PRODUCING AMBREIN
An object of the present invention is to provide a method for preparing ambrein, which can easily obtain the ambrein. The object can be solved by a mutated...
2019/0078119 NOVEL AAV8 MUTANT CAPSIDS AND COMPOSITIONS CONTAINING SAME
Provided herein are AAV8 mutant capsids and rAAV comprising the same. In one embodiment, vectors employing the AAV8 mutant capsid show increased transduction...
2019/0078118 PLANTS COMPRISING WHEAT G-TYPE CYTOPLASMIC MALE STERILITY RESTORER GENES, MOLECULAR MARKERS AND USES THEREOF
Methods are described for selecting or producing a cereal plant comprising a functional restorer gene for wheat G-type cytoplasmic male sterility and nucleic...
2019/0078117 METHOD FOR THE PRODUCTION OF HAPLOID AND SUBSEQUENT DOUBLED HAPLOID PLANTS
It was found that plants comprising modified CENPC protein comprising one or more active mutations which affect the functioning of CENPC protein yet allow...
2019/0078116 RNAS FROM PATHOGENS INHIBIT PLANT IMMUNITY
Provided are pathogen-resistant plants comprising a heterologous expression cassette, the expression cassette comprising a promoter operably linked to a...
2019/0078115 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF
Soybean plants comprising event SYHT0H2, methods of detecting and using the same, and soybean plants comprising a heterologous insert at the same site as SYHT0H2.
2019/0078114 PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES
Provided is a plant or plant part comprising a polynucleotide encoding a mutated cellulose synthase (CESA) polypeptide, wherein the expression of said...
2019/0078113 MODULATION OF SEED VIGOR
The present invention provides a polynucleotide which enables the modulation of the seed vigour, and in particular enhances the seed vigour, and more...
2019/0078112 Compositions and Methods for Producing Tobacco Plants and Products Having Reduced or Eliminated Suckers
The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in...
2019/0078111 CANOLA VARIETY 45CM36
Provided is a canola variety designated 45CM36 and seed, plants and plant parts thereof produced from a cross of inbred varieties. Methods for producing a...
2019/0078110 CANOLA VARIETY 45H37
Provided is a canola variety designated 45H37 and seed, plants and plant parts thereof produced from a cross of inbred varieties. Methods for producing a...
2019/0078109 CANOLA VARIETY 45M38
Provided is a canola variety designated 45M38 and seed, plants and plant parts thereof produced from a cross of inbred varieties. Methods for producing a...
2019/0078108 SOYBEAN CULTIVAR UB12520200
The present invention is in the field of soybean variety UB12520200 breeding and development. The present invention particularly relates to the soybean variety...
2019/0078107 CANOLA VARIETY D3156M
Provided is a canola variety designated D3156M and seed, plants and plant parts thereof produced from a cross of inbred varieties. Methods for producing a...
2019/0078106 METHODS AND COMPOSITIONS OF IMPROVED PLANT TRANSFORMATION
The present disclosure provides methods and compositions for the vectors comprising vir genes. The present disclosure further provides a vector comprising: (a)...
2019/0078105 KAURENOIC ACID HYDROXYLASES
The present invention relates a variant polypeptide having kaurenoic acid 13-hydroxylase activity, which variant polypeptide comprises an amino acid sequence...
2019/0078104 NOVEL EPISOMAL PLASMID VECTORS
An episomal plasmid comprising a gene of interest (GOI) and an autonomously replicating sequence (ARS) which is not operably linked to the GOI, which ARS...
2019/0078103 METHODS OF PRODUCING 6-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, 6-hydroxyhexanoic acid, hexamethylenediamine or...
2019/0078102 BIOSYNTHETIC PRODUCTION OF STEVIOL GLYCOSIDES AND PROCESSES THEREFORE
The present invention relates to the production of steviol glycoside rebaudiosides D4, WB1 and WB2 and the production of rebaudioside M from Reb D4.
2019/0078101 METHOD OF PREPARING PORCINE CIRCOVIRUS TYPE 2 CAPSID PROTEIN AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
The present invention provides a preparation method for PCV2 capsid protein and a pharmaceutical composition containing said capsid protein. The method of the...
2019/0078100 ENGINEERED BENZYLISOQUINOLINE ALKALOID EPIMERASES AND METHODS OF PRODUCING BENZYLISOQUINOLINE ALKALOIDS
The present disclosure provides systems and methods for increasing production of an alkaloid product through the epimerization of a (S)-1-benzylisoquinoline...
2019/0078099 CELL LINE FOR RECOMBINANT PROTEIN AND/OR VIRAL VECTOR PRODUCTION
Cells and cell lines are disclosed that are able to produce therapeutic proteins, antibodies, vectors, and viral vectors such as lentiviral vectors and...
2019/0078098 COMPOSITIONS AND METHODS FOR TYPE III POLYKETIDE PRODUCTION IN OLEAGINOUS YEAST SPECIES
This invention relates to compositions and methods for the production of Type III polyketides using genetically modified oleaginous yeast strains, for example,...
2019/0078097 Polynucleotide Constructs For In Vitro and In Vivo Expression
The present invention relates to polynucleotide constructs for in vitro and in vivo transcription/translation of genes of interest or variants of a gene of...
2019/0078096 COMBINATION VECTORS AND METHODS FOR TREATING CANCER
A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is...
2019/0078095 ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS
Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm...
2019/0078094 Aptamer specifically binding to L-Ascorbic acid and use of the same
The present invention relates to a single-stranded DNA aptamer which inhibits oxidation by binding to L-ascorbic acid, characterized in that the single...
2019/0078093 OLIGONUCLEOTIDE PROBES AND USES THEREOF
Methods and compositions are provided to identify oligonucleotides that bind targets of interest. The targets include tissues, cells, circulating biomarkers...
2019/0078092 PREVENTING TUMOR DEVELOPMENT AND METASTASIS
Treatment of tumors, especially breast cancer or glioblastoma tumors, by silencing RAB27A and/or TRAF3IP2, compositions and methods for same.
2019/0078091 ANTISENS OLIGONUCLEOTIDES FOR THE TREATMENT OF LEBER CONGENITAL AMAUROSIS
The present invention relates to the fields of medicine and immunology. In particular, it relates to novel antisense oligonucleotides that may be used in the...
2019/0078090 DOWNREGULATING MIR-132 FOR THE TREATMENT OF LIPID RELATED DISORDERS
A method of treating a lipid-related disorder in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically...
2019/0078089 RNAi Agents And Compositions for Inhibiting Expression of Angiopoietin-Like 3 (ANGPTL3), And Methods Of Use
The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, able to inhibit Angiopoietin-like 3 (also called ANGPTL3, ANGPL3, ...
2019/0078088 RNAi Agents And Compositions for Inhibiting Expression of Apolipoprotein C-III (APOC3)
The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, capable of inhibiting Apolipoprotein C-III (also called APOC3, apoC-III,...
2019/0078087 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER
The disclosure provides polynucleotides encoding a polypeptide including a morpholino linker. In some embodiments, the polynucleotides of the invention have...
2019/0078086 METHODS AND COMPOSITIONS TO TREAT DRUG-INDUCED DISEASES AND CONDITIONS
Methods and compounds useful to treat drug-induced diseases and conditions are provided. Methods of administering one or more MCJ-inhibiting compounds to...
2019/0078085 NORMALIZATION FOR SEQUENCING LIBRARIES
Embodiments of a method and/or system, such as for preparation of a normalized library for sequencing such as next-generation sequencing, can include one or...
2019/0078084 METHODS AND KITS FOR NUCLEIC ACID SAMPLE PREPARATION FOR SEQUENCING
The present disclosure relates to methods and kits for DNA library construction, particularly for consistent and reproducible DNA sequencing.
2019/0078083 METHOD FOR CONTROLLED DNA FRAGMENTATION
A composition and method for controlled in vitro fragmentation of nucleic acids. A transposase forms catalytically active complexes with a modified transposon...
2019/0078081 METHOD OF IMPROVING CHARACTERISTICS OF PROTEINS
The invention provides efficient methods for combining single-substitution libraries of nucleic acids that span and encode proteins of interest and for...
2019/0078080 METHODS AND SYSTEMS AND RELATED COMPOSITIONS FOR MIXTURES SEPARATION WITH A SOLID MATRIX
Methods and systems and related compositions for separating through a solid matrix a mixture comprising a nucleic acid together with a target compound having a...
2019/0078079 METHODS FOR PURIFYING NUCLEIC ACIDS AND DEVICES THEREOF
A nucleic acid purification device includes a housing and an adapter operatively attached to the housing. The adapter is configured to receive at least one...
2019/0078078 METHODS FOR EXTRACELLULAR VESICLE ISOLATION AND SELECTIVE REMOVAL
Disclosed is a method for the isolation of extracellular vesicles, including exosomes, from a liquid sample, the method comprising the steps of: adjusting the...
2019/0078077 CAPILLARY BARRIERS FOR STAGED LOADING OF MICROFLUIDIC DEVICES
Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic...
2019/0078076 SITE-SPECIFIC INTEGRATION OF TRANSGENES
Provided is a method for knocking in a gene of interest to a cell. The genome of the cell contains a negative selectable marker, e.g., a thymidine kinase gene...
2019/0078075 DP04 POLYMERASE VARIANTS
Recombinant DPO4-type DNA polymerase variants with amino acid substitutions that confer modified properties upon the polymerase for improved single molecule...
2019/0078074 OBESITY RISK DIAGNOSIS KIT AND METHOD FOR ANALYZING RISK OF OBESITY ONSET
To provide an obesity risk diagnosis kit and a method for analyzing the risk of obesity onset. An obesity risk diagnosis kit including a probe for analyzing...
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