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Patent # Description
2019/0135753 PIPERIDINYL DERIVATIVES
Compounds of the formula I ##STR00001## in which X, Y, R.sup.1 and R.sup.2 have the meanings indicated in claim 1, are inhibitors of pyruvate dehydrogenase...
2019/0135752 SUBSTITUTED (1,2,3,4-TETRAHYDROCYCLOPENTA[b]INDOL-3-YL)ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF...
The present invention relates to certain substituted 1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid derivatives of Formula (Ia) and pharmaceutically...
2019/0135751 SMALL MOLECULE N-(ALPHA-PEROXY) CARBAZOLE COMPOUNDS AND METHODS OF USE
The invention relates to novel N-(.alpha.-peroxy)carbazole compounds of Formula I and methods for use. (I) The N-(.alpha.-peroxy)carbazole compounds described...
2019/0135750 METHODS AND SYSTEMS FOR THE MANUFACTURE OF AN AROMATIC PHTHALIC BISIMIDE AND A POLYETHERIMIDE
A method for producing an aromatic bisimide includes reacting a dialkali metal salt of a dihydroxy aromatic compound with a reactive substituted phthalimide...
2019/0135749 Production of Cyclic Imides Suitable for Oxidation Catalysis
Disclosed are novel processes for the production of cyclic imide compounds such as N-hydroxyphthalimide (NHPI). The processes may be particularly well-suited...
2019/0135748 METHODS OF MANUFACTURE OF 2-ARYL-3,3-BIS(4-HYDROXYARYL)PHTHALIMIDINES, AND POLYMERS DERIVED THEREFROM
A method for the manufacture of a 2-aryl-3,3-bis(hydroxyaryl)phthalimidine including heating a reaction mixture comprising a phenolphthalein compound and a...
2019/0135747 INDOLE AND INDAZOLE CYANOCINNAMATE COMPOUNDS AND THERAPEUTIC USES THEREOF
Disclosed are Indole and Indazole cyanocinnamate compounds, method for preparing these compounds, and methods for treating cancer.
2019/0135746 INDOLINE DERIVATIVES AND METHOD FOR USING AND PRODUCING THE SAME
The present invention relates to a compound of the formula: where n, R and R are those defined herein. The present invention also relates to use of a compound...
2019/0135745 IMMUNOMODULATOR COMPOUNDS
Compounds are provided that are useful as immunomodulators. The compounds have the following Formula (I): ##STR00001## including stereoisomers and...
2019/0135744 IDENTIFYING PATIENT RESPONSE TO S1P RECEPTOR MODULATOR ADMINISTRATION
The invention provides a method of assessing the appropriate therapeutic dose of 1-{4-[1-(4-cyclohexyl-3-trifluoromethyl-benzyloxyimino)-ethyl]-2-- ...
2019/0135743 NOVEL PROSTAGLANDIN DERIVATIVE
The present invention relates to a novel prostaglandin derivative having an alkynyl group on .omega.-chain, particularly, a novel prostaglandin derivative...
2019/0135742 PLEUROMUTILIN DERIVATIVE HAVING 2-AMINO PHENYL MERCAPTAN SIDE CHAIN AS WELL AS PREPARATION METHOD AND...
A pleuromutilin derivative having a 2-amino phenyl mercaptan side chain as well as a preparation method and application thereof are provided. The derivative...
2019/0135741 Methods of Making Deuterium-Enriched N-acetylcysteine Amide (D-NACA) and (2R, 2R')-3,3'-Disulfanediyl...
The present invention includes pharmaceutical composition comprising (2R,2R')-3,3'-disulfanediyl bis(2-acetamidopropanamide)(diNACA) or D.sub.3-N-acetyl...
2019/0135740 SYNTHESIS OF 2,2,2-TRIFLUOROETHANETHIOL
A method of making CF.sub.3CH.sub.2SH, comprising a step of reacting CF.sub.3CH.sub.2X, wherein X is halide or tosylate, with MSH, where M is an alkali metal...
2019/0135739 PROCESS FOR PRODUCING TAURINE
There is disclosed a process for producing taurine by reacting 2-oxazolidinone with ammonium sulfite, or ammonium bisulfite, or a mixture of ammonium sulfite...
2019/0135738 TUNABLE NITRIC OXIDE-RELEASING MACROMOLECULES HAVING MULTIPLE NITRIC OXIDE DONOR STRUCTURES
Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such...
2019/0135737 METHOD FOR PRODUCING XYLYLENE DIISOCYANATE (XDI)
Disclosed is to a method for producing xylylene diisocyanate (XDI), in particular meta-xylylene diisocyanate (mXDI), including the following steps: a)...
2019/0135736 PROCESS FOR REDUCING CPI IN A DINITRILE STREAM
Disclosed is a process for removing 2-cyanocyclopentylideneimine (CPI) from a mixture containing CPI and dinitrile. The process comprises reacting CPI with an...
2019/0135735 METHOD FOR PRODUCING N-(ALPHA-ALKOXYETHYL)FORMAMIDE
Provided are a method for producing N-(.alpha.-alkoxyethyl)formamide, comprising adding an acid catalyst to the mixed liquid within 3 hours from start of...
2019/0135734 METHOD FOR PRODUCING SURFACTANTS
The present invention relates to a method in which an amino acid is reacted with an acyl group donor to obtain an N-acylamino acid in the presence of an amine.
2019/0135733 CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF
Disclosed are a class of compounds as a caspase inhibitor, and in particular the compound as shown in formula (I) or a pharmaceutically acceptable salt...
2019/0135732 CRYSTAL FORMS AND METHODS OF SYNTHESIS OF (2R, 6R)-HYDROXYNORKETAMINE AND (2S, 6S)-HYDROXYNORKETAMINE
The disclosure provides a method for synthesizing free base forms of (2R,6R)-hydroxynorketamine (HNK) and (2S,6S)-hydroxynorketamine. In an embodiment...
2019/0135731 N,N-DIMETHYLAMINOETHYL ACRYLATE COMPOSITION STABILIZED IN RESPECT OF DISCOLORING EFFECTS
The invention relates to the use of 2,6,-di-tert-butyl-4-methylphenol at a moiety of 25 to 200 ppm for stabilizing N,N-dimethylaminoethyl acrylate in respect...
2019/0135730 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING...
Provided are an organic electric element and an electronic device comprising the same. According to the present invention, the organic electric element uses a...
2019/0135729 PRODUCTION OF SALTS OF 4-HYDROXYBUTYRATE USING BIOBASED RAW MATERIALS
Gamma-butyrolactone ("GBL") and Gamma-hydroxybutyrate ("GHB") having a unique carbon footprint as defined by the percent modern carbon (pmc) are described...
2019/0135728 Method for Purifying an Aqueous Lactic Acid Solution
The present invention concerns a method for purifying an aqueous lactic acid solution, obtained from a fermentation medium or from any other source previously...
2019/0135727 Continuous method for producing muconic acid from aldaric acid
According to an example aspect of the present invention, there is provided a continuous method of producing muconic acid from aldaric acid in the presence of a...
2019/0135726 Process For The Sustainable Production Of Acrylic Acid
A process for the production of organic acids having at least three carbon atoms comprises the steps of forming an amount of carbon monoxide and reacting the...
2019/0135725 PROCESS FOR PREPARING SUBSTITUTED CROTONIC ACIDS
A process to prepare a compound of Formula (I) ##STR00001## wherein R.sup.3, R.sup.4 and R.sup.5 are each selected independently from hydrogen, halogen, alkyl,...
2019/0135724 Systems And Methods For Producing Synthetic Hypericin
Improved systems and methods for producing synthetic hypericin at high volume and high purity.
2019/0135723 PROCESS FOR THE RECOVERY OF KETONES AND GLYCOLS FROM FERMENTATION
Methods may include obtaining ketones and glycols from a fermentation process, the method including: collecting an off-gas and/or a fermented broth from the...
2019/0135722 METHOD FOR PRODUCING PROPIONALDEHYDE
To provide a method for producing propionaldehyde directly from glycerol with high yield, gasified glycerol is brought into contact with a silica-type regular...
2019/0135721 METHOD FOR MANUFACTURING 1,4-BIS (4-PHENOXYBENZOYL)BENZENE IN SUPERSATURATION CONDITIONS
A method for manufacturing 1,4-bis(4-phenoxybenzoylbenzene), including: providing a reactant mixture including terephthaloyl chloride, diphenyl ether and a...
2019/0135720 METHOD OF PRODUCING ALCOHOL ALKOXYLATES
A method of producing alcohol alkoxylates comprising contacting a hydrocarbon mixture with a hydroformylation catalyst under hydroformylation conditions to...
2019/0135719 A METHOD FOR THE CONTINUOUS MANUFACTURE OF BISPHENOL A
In an embodiment, a method for the continuous manufacture of bisphenol A comprises reacting phenol and acetone in the presence of an acidic catalyst to form a...
2019/0135718 SMALL MOLECULE INHIBITORS OF NECROPTOSIS
The invention features a series of heterocyclic derivatives that inhibit tumor necrosis factor alpha (TNF-.alpha.) induced necroptosis. The heterocyclic...
2019/0135717 PROCESS FOR PREPARING A CHLORINATED ALKENE
Disclosed is a process for preparing a chlorinated alkene, comprising contacting a chlorinated alkane with a catalyst in a dehydrochlorination zone to produce...
2019/0135716 TREATING C8- C10 AROMATIC FEED STREAMS TO PREPARE AND RECOVER TRIMETHYLATED BENZENES
Methods are provided for the treatment of a feed stream containing C9 aromatic components to produce mesitylene-containing products. The methods include...
2019/0135715 CONTROLLING CARBON DIOXIDE OUTPUT FROM AN ODH PROCESS
In some embodiments provided herein are processes for controlling carbon dioxide output levels coming from an oxidative dehydrogenation (ODH) process. Carbon...
2019/0135714 METHOD FOR PRODUCING CONJUGATED DIENE
Provided is a method of producing a conjugated diene, including a step of dehydrating a .gamma.,.delta.-unsaturated alcohol in the presence of a solid acid...
2019/0135713 Automatic Matchmaking Device
This invention discloses an automatic matchmaking device, comprising a machine body, a cylindrical machining cavity arranged in the machine body, a material...
2019/0135712 EXPLOSIVE COMPOSITION FOR USE IN TELESCOPICALLY EXPANDING NON-LETHAL TRAINING AMMUNITION
An explosive composition for use in telescopically expanding non-lethal training ammunition comprises tetrazene and paraffin wax. The explosive composition can...
2019/0135711 NUTRIENT-CONTAINING POROUS BIODEGRADABLE BEAD
The present disclosure relates to a nutrient-containing porous biodegradable bead comprising the following components: an Aloe Vera and cellulose composite...
2019/0135709 Environmentally Friendly Fertilizer Device Based on Big Data
The invention discloses an environmentally friendly fertilizer device based on big data, comprising a work box and a crushing space set in the work box,...
2019/0135708 PRODUCTION METHOD FOR DIPEPTIDE-CONTAINING GRANULES
The present invention relates to a process for producing a particulate composition containing methionine, methionylmethionine, potassium in the form of...
2019/0135707 CEMENTITIOUS COMPOSITE CONSTITUENT RELATIONSHIPS
A cementitious composite includes a cementitious mixture of cementitious materials and non-cementitious materials. Prior to the in-situ hydration, ...
2019/0135706 COPPER-CERAMIC BONDED BODY AND INSULATION CIRCUIT SUBSTRATE
In a copper-ceramic bonded body of the present invention, at a bonding interface of a copper member and a ceramic member, there are formed a nitride compound...
2019/0135705 POWDER FOR ADDITIVE MODELING, STRUCTURE, SEMICONDUCTOR PRODUCTION DEVICE COMPONENT, AND SEMICONDUCTOR...
A material powder for additive modeling including a nitride, and a eutectic oxide, the nitride having an average density lower than an average density of the...
2019/0135704 METHODS OF MINIMIZING PARTICLES ON WAFER FROM PLASMA SPRAY COATINGS
Methods comprise performing two or more thermal cycles on an article comprising a body and a ceramic coating. Each thermal cycle of the two or more thermal...
2019/0135703 SYSTEMS AND METHODS FOR MAKING CERAMIC POWDERS
Systems and methods for making ceramic powders configured with consistent, tailored characteristics and/or properties are provided herein. In some embodiments...
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