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Patent # Description
US-7,994,356 Mono ethylenically unsaturated polycarbosiloxane monomers
The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention...
US-7,994,355 Metallocene-based chiral phosphine or arsine ligands
The present invention relates to metallocene-based phosphine ligands having chirality at phosphorus and at least one other element of chirality (planar...
US-7,994,354 Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes
Methods to convert biobased oils, oil derivatives, and modified oils to highly functionalized esters, ester polyols, amides, and amide polyols. The products can...
US-7,994,353 PPAR activity regulators
The present invention provides PPAR (peroxisome proliferator-activated receptor) activity regulators, which can be widely used for improving insulin resistance...
US-7,994,352 Process for preparing 3a(.beta.)-7a(.beta.)-dihydroxy-6a(.beta.)-alkyl-5.beta.-cholanic acid
Process for preparing 3.alpha.-7.alpha.(.beta.)-dihydroxy-6.alpha.(.beta.)-alkyl-5.beta.-cholan- ic acid (I) in which R is a linear or branched C.sub.1-C.sub.5...
US-7,994,351 Preparation of bile acids and intermediates thereof
Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
US-7,994,350 Process for continuously preparing N-ethyl-2-pyrrolidone (NEP)
Process for the continuous preparation of N-ethyl-2-pyrrolidone (NEP) by reacting gamma-butyrolactone (GBL) with monoethylamine (MEA) in the liquid phase,...
US-7,994,349 Process for producing of epoxy compound
An object of the present invention is to provide an efficient process for producing an epoxy compound from olefin, oxygen and hydrogen. The process of the...
US-7,994,348 Process for producing propylene oxide
A process for producing propylene oxide, which comprises: supplying a solution containing a peroxide selected from the group consisting of hydrogen peroxide...
US-7,994,347 Hydroxymethylfurfural reduction methods and methods of producing furandimethanol
A method of reducing hydroxymethylfurfural (HMF) where a starting material containing HMF in a solvent comprising water is provided. H.sub.2 is provided into...
US-7,994,346 Intermediates for the preparation of lipoxin A.sub.4 analogs
This invention is directed to compounds useful as intermediates in the synthesis of lipoxin A.sub.4 analogs of the following formulas (I) and (II): ...
US-7,994,345 Process for the purification of thiophenes
The invention relates to a process for the purification of thiophenes by means of precipitation. The purified thiophenes are liquid at room temperature, have a...
US-7,994,344 Intermediates for the production of optically active cyclopropylamine derivatives and process for the...
A process for producing an optically active compound represented by formula (4) or a salt thereof: ##STR00001## the process including reacting a cyclization...
US-7,994,343 Process for the production of atorvastatin calcium in amorphous form
A process for the production of amorphous atorvastatin calcium and stabilized, amorphous atorvastatin calcium is provided.
US-7,994,342 Method for producing optically active succinimide compound
There is provided a novel method for producing an optically active succinimide compound which is a useful compound utilized as an intermediate raw material for...
US-7,994,341 Process for the production of amides
The present invention relates to a process for the preparation of compounds of formula (I) wherein R.sub.1 and R.sub.2 are each independently of the other...
US-7,994,340 Azolylmethyloxiranes, their use for controlling phytopathogenic fungi, and compositions comprising them
The present invention relates to azolylmethyloxiranes of the general formula (I) in which A stands for phenyl which is optionally substituted by one to three of...
US-7,994,339 Phthalamide derivative, agricultural or horticultural pesticide, and use of the pesticide
Disclosed is a phthalamide derivative represented by the general formula (I) or a salt thereof, which shows an excellent controlling effect for use as an...
US-7,994,338 Small molecule inhibitors of kynurenine-3-monooxygenase
The present invention relates to compounds of formula Ia or Ib below and their tautomers and/or pharmaceutically acceptable salts and compositions and methods...
US-7,994,337 Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors
A compound of Formula (I) ##STR00001## an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, wherein A is independently selected from: ...
US-7,994,336 Azetidine compounds as orexin receptor antagonists
The invention relates to novel azetidine compounds of formula (I), wherein R.sup.1, R.sup.2, and X are as described in the description and their use as orexin...
US-7,994,335 Electronically tuned ligands for asymmetric hydrogenation
Disclosed is a new class of chiral bidentate ligands capable of performing asymmetric hydrogenation. Also disclosed are processes of performing asymmetric...
US-7,994,334 Fungicide pyridinyloxy substituted phenylamidine derivatives
The present invention relates to 2,5-di-substituted-4-pyridinyloxy-substituted-phenyl-amidine derivatives, notably to...
US-7,994,333 Methods and compositions for selectin inhibition
The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian...
US-7,994,332 Process for producing crystal
The present invention relates to a production method of a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]ben- ...
US-7,994,331 Heterocycle-substituted benzimidazole derivative
A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: (I) wherein X.sub.1 to X.sub.4 independently represent a carbon atom or...
US-7,994,330 Method for producing organic compound and method for decomposing compound having dicarboximide skeleton
It is desirable to provide a method for easily removing catalyst-derived impurities from a product of a reaction by the catalysis of a compound having a...
US-7,994,329 Growth hormone secretagogue receptor type 1A agonists
Compounds that are ligands for the growth hormone secretagogue receptor type 1A (GHS-R 1A), as well as pharmaceutically acceptable salts of such compounds, are...
US-7,994,328 Process for the preparation of donepezil hydrochloride
The present invention relates to an improved process for the preparation of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride of Formula...
US-7,994,327 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds
The present invention provides new processes for the preparation of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione...
US-7,994,326 Potent and highly selective heteroaromatic inhibitors of neuronal nitric oxide synthase
Peptidomimetic compounds as can inhibit neuronal nitric oxide synthase (nNOS) for potential treatment in neurodegenerative diseases, such as but not limited to...
US-7,994,325 CGRP receptor antagonists
Compounds of Formula I: ##STR00001## (where variables R.sup.1, A, B, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful...
US-7,994,324 2-aminoquinoline derivatives
The present invention is concerned with 2-aminoquinoline derivatives, in particular compounds of formula (I) ##STR00001## wherein R.sup.1 and R.sup.2 are as...
US-7,994,323 Chromen-2-one derivatives
This invention relates to novel chromen-2-one derivatives useful as starting material for synthesis of pharmaceuticals. On other aspects the invention relates...
US-7,994,322 Processes for the preparation of different forms of (S)-(+)-clopidogrel besylate
Disclosed herein are the improved processes for the preparation of different forms of (S)-(+)-Clopidogrel besylate, pharmaceutical compositions containing them...
US-7,994,321 Substituted thieno[3,2-C]pyridine-7-carboxylic acid derivatives
There are provided compounds of the formula ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, X, Y, Q, Ring A and Ring B are as described. The compounds exhibit...
US-7,994,320 Narcistatin prodrugs
The present invention provides prodrugs derived from the sparingly soluble anticancer isocarbostyril narciclasine, a component of various Narcissus species,...
US-7,994,319 Light-emitting material comprising orthometalated iridium complex, light-emitting device, high efficiency red...
A synthesis method of a compound represented by formula (23), the method comprising reacting at least one of a ligand and a dissociation product thereof with an...
US-7,994,318 Coumarin derivatives useful as TNF.alpha. inhibitors
Novel compounds composition capable of inhibiting TNF.alpha. and having antiimmunionflammatory and autoimmune properties useful in a pharmaceutical composition,...
US-7,994,317 sEH inhibitors and their use
The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme.
US-7,994,316 1,3,5-triazine derivative, production method thereof and organic electroluminescence device comprising this as...
Since the conventional electron transporters have low thermal stability, the organic electroluminescent devices using them are not sufficient in terms of the...
US-7,994,315 Intermediate compound for synthesizing pharmaceutical agent and production method thereof
Production method of an optically active morpholine compound represented by the formula 10, or a compound represented by the formula 55, which includes the...
US-7,994,314 Method for the preparation of an enantiomerically pure benzazepine
The invention relates to the preparation of mirtazapine precursors and mirtazapine preferably having a substantial enantiomeric excess.
US-7,994,313 Unsolvated benzodiazepine compositions and methods
The present invention relates to systems and methods for generating new forms of benzodiazepine and benzodiazepine related compounds as well as new compounds...
US-7,994,312 Synthetic route to ABCD-porphyrins
A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting...
US-7,994,311 Fluorescent chemosensors for metals based on dipyrrins
The present invention is a new class of fluorescent sensor with unprecedented sensitivity, selectivity and synthetic efficiency for the identification and...
US-7,994,310 Process for preparing 2'-deoxy-2', 2'-difluorocytidine
Disclosed is a method for preparing 2'-deoxy-2',2'-difluorocytidine of Formula I comprising, preparing an optically pure 3R-hydroxypropane amide compound of...
US-7,994,309 Compositions and methods for inhibiting expression of a mutant gene
The present invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a mutant gene, comprising a complementary RNA...
US-7,994,307 RNAi modulation of the BCR-ABL fusion gene and uses thereof
The invention relates to compositions and methods for modulating the expression of Bcr-Abl, and more particularly to the down-regulation of Bcr-Abl mRNA and...
US-7,994,306 Methods of treating cancer using siRNA molecules directed against CD24
A method of treating a CD24-related medical condition is disclosed. The method comprises administering to a subject in need thereof at least one siRNA molecule...
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