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Patent # Description
US-7,994,305 Compositions and methods for siRNA inhibition of angiopoietin 1 and 2 and their receptor Tie2
RNA interference using small interfering RNAs which are specific for mRNA produced from the Ang1, Ang2 or Tie2 genes inhibits expression of these genes....
US-7,994,304 Methods and compositions for sequencing a nucleic acid
The invention provides a family of tethered nucleotide analogs useful in sequencing nucleic acids containing a homopolymer region comprising, for example, two...
US-7,994,303 Penaeidin gene promoters in tiger shrimp and applications thereof
The present invention relates to new penaeidin gene promoters found in tiger shrimps and applications thereof. The promoters of the invention are useful for the...
US-7,994,302 Fully human monoclonal antibodies to IL-13
The present invention is related to antibodies directed to IL-13 and uses of such antibodies. For example, in accordance with the present invention, there are...
US-7,994,301 Modulators of body weight, corresponding nucleic acids and proteins
Modulators of weight, including, for example, two isoforms of murine and human ob polypeptides, are provided, as well as diagnostic and therapeutic uses and...
US-7,994,300 Diagnostic methods involving determining gene copy numbers and SNPs in the FcyRII/FcyRIII gene cluster, and...
The invention relates to diagnostic methods to predict whether a subject is predisposed for acquiring a disease or to predict the therapy responsiveness of an...
US-7,994,299 Compositions and methods for increasing bone mineralization
A novel class or family of TGF-.beta. binding proteins is disclosed. Also disclosed are assays for selecting molecules for increasing bone mineralization and...
US-7,994,298 Chimeric NK receptor and methods for treating cancer
The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like...
US-7,994,297 Method of spotting probes on a solid support
Provided is a method of spotting a probe densely and efficiently on a surface of a solid support. A liquid containing a probe is attached to a solid support as...
US-7,994,296 Arrays, computer program products and methods for in silico array-based comparative binding assays
The invention provides computer systems, computer program products and methods for in silico array-based methods for determining the relative amount of...
US-7,994,295 Recombinant viruses comprising the membrane-proximal domain of VSV G protein
Recombinant viruses, isolated nucleic acids and methods of generating same encoding for a Rhabdoviral G stem polypeptide are disclosed. Methods, compounds and...
US-7,994,294 Nucleic acids and polypeptides related to a guanine exchange factor of Rho GTPase
The present invention relates to all aspects of a guanine exchange factor (GEF), for example, a Rho-GEF, such as p115 Rho-GEF. A GEF modulates cell signaling...
US-7,994,293 Antibodies specific for Dkk-1
Antibodies specific for Dkk-1, an inhibitor of the osteoanabolic Wnt/LRP5 signaling pathway, are described. The antibodies, which inhibit binding of Dkk-1 to...
US-7,994,292 MU-1, member of the cytokine receptor family
Polynucleotides encoding the MU-1 hematopoietin receptor superfamily chain and fragments thereof are disclosed. MU-1 proteins, antibodies (and fragments...
US-7,994,291 Human E3.alpha. ubiquitin ligase family
The present invention relates to a novel polypeptide encoding a protein which is the full length human ortholog of E3.alpha. ubiquitin ligase. The invention...
US-7,994,290 Effector function enhanced recombinant antibody composition
The present invention relates to a recombinant antibody composition which is a human IgG1 antibody, comprises a CH2 domain in which amino acids at positions 276...
US-7,994,289 Humanized anti-CD3 antibodies
An IgG antibody is provided having a binding affinity for the CD3 antigen complex in which in the heavy chain has a variable region framework together with at...
US-7,994,288 Allergenic proteins of natural rubber latex, their production and use in assays
This invention relates to allergenic proteins of natural rubber latex in substantially purified form, their production and their use, together with monoclonal...
US-7,994,287 Antibodies which bind human CXCR3
Antibodies and antigen-binding fragments of antibodies that bind human CXCR3 are disclosed. In preferred embodiments, the antibodies are human. Nucleic acids...
US-7,994,286 Neuropilin antagonists
Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies...
US-7,994,285 Anti-Notch3 antibodies
The present invention relates to novel antibodies that bind specifically to human Notch 3 and their use in the detection and/or diagnosis of Notch 3 related...
US-7,994,284 Connective tissue growth factor (CTGF-3) polypeptides
The present invention relates to a novel connective tissue growth factor-3 protein which is a member of the growth factor superfamily. In particular, isolated...
US-7,994,283 Dimeric proteins for immunization
A dimeric protein comprising a first fusion protein and a second fusion protein, wherein the first fusion protein comprises a targeting domain, a leucine zipper...
US-7,994,282 Card proteins involved in cell death regulation
The present invention provides NB-ARC and CARD-containing proteins (NACs), nucleic acid molecules encoding NACs and antibodies specific for at least one NAC....
US-7,994,281 Cytokine design
The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as...
US-7,994,280 On-resin peptide cyclization
A novel compound of formula I is devised. ##STR00001##
US-7,994,279 Altered peptide ligands of GAD65
Modified GAD65 compositions antagonize the activities of islet-specific T cells that contribute to the progression of one or more autoimmune disorders. The...
US-7,994,278 Biologically active polypeptides derived from a novel early stage pregnancy factor designated maternin (MA)
The invention relates to therapeutic polypeptides isolated from beta-human chorionic gonadotropin (.beta.-hCG) found in human early pregnancy urine, now...
US-7,994,277 IFBM's to promote the specific attachment of target analytes to the surface of orthopedic implants
The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is...
US-7,994,276 Composition of tumour-associated peptides and related anti-cancer vaccine
The present invention relates to immunotherapeutic peptides and their use in immunotherapy, in particular the immunotherapy of cancer. The present invention...
US-7,994,275 Method for extruding polymers
The disclosure defined by this invention provides a method for extruding thermoplastic polymers which includes the step of creating high pressure steam in the...
US-7,994,274 Two-stage cure polyimide oligomers
A method for using citraconic anhydride and itaconic anhydride as addition cure end caps in reactions for forming polyamic acid oligomers and polyimide...
US-7,994,273 Photoactive materials
Diamine compounds, which in particular are useful as precursors for the production of liquid crystal alignment layers, are represented by the general formula I:...
US-7,994,272 Maleamic acid polymer derivatives and their bioconjugates
The present invention is directed to maleamic acid derivatives of water soluble polymers, to chemically stable water-soluble polymer succinamic acid-active...
US-7,994,271 Phenolic resin, production method and use thereof
Disclosed is a phenolic resin having flame retardance, fast curing property and low melt viscosity, which is useful for a curing agent for epoxy resin-based...
US-7,994,270 Method for producing thermosetting resin having benzoxazine ring
The present invention provides a method for producing a thermosetting resin having a benzoxazine ring, comprising the step of: reacting a bifunctional phenol...
US-7,994,269 Golf equipment formed from castable formulation with unconventionally low hardness and increased shear resistance
Golf equipment including compositions including castable formulations that have low material hardness and increased shear resistance. The compositions may be...
US-7,994,268 Cardanol based dimers and uses therefor
Cardanol based dimers are provided. The cardanol dimers are formed by hydrosilylation with silanes. Cardanol based dimers may be further reacted to form epoxy...
US-7,994,267 Polymerization catalyst compositions containing metallocene complexes and polymers produced by using the same
The present invention provides a novel catalyst composition comprising a metallocene complex, and a novel producing method for various polymer compounds....
US-7,994,266 Dropping method for liquids
In a process for dropletizing a liquid by means of a dropletizer plate at least the underside of the dropletizer plate has at least in part a contact angle of...
US-7,994,265 Vinyl alcohol copolymers for use in aqueous dispersions and melt extruded articles
In a method of preparing an aqueous dispersion selected from drilling fluids, hydraulic cement compositions, mineral pigment containing coatings, and...
US-7,994,264 Slurry phase polymerisation process
Process comprising polymerizing in a loop reactor of a continuous tubular construction an olefin monomer optionally together with an olefin comonomer in the...
US-7,994,263 Reaction product of epoxy resins, bisphenol, xylene-formaldehyde and amine in cationic electrodeposition paint
This invention discloses a cationic electrodeposition paint composition containing an amino group-containing modified epoxy resin which is obtained through...
US-7,994,262 Hardenable composition
The present invention has its object to provide a reactive silyl group-containing room temperature curable composition which can give cured products having good...
US-7,994,261 Highly elastomeric and paintable silicone compositions
Highly elastomeric, curable, paintable silicone compositions are provided. The paintable silicone compositions comprise an organopolysiloxane, a silicone...
US-7,994,260 Fuel comprising an emulsion between water and a liquid hydrocarbon
A polymeric surfactant obtained by the reaction of: (i) a polyolefin oligomer functionalized with at least one group deriving from a dicarboxylic acid, or a...
US-7,994,259 Polymer comprising amide and ester groups, method for production and use thereof
The invention relates to a method for the production of a polymer (P) comprising amide and ester groups, whereby, in a first step, a homo- or co-polymer (P1) of...
US-7,994,258 Hyperbranched polymer having nitroxyl group
There is provided a hyperbranched polymer having a nitroxyl group. A hyperbranched polymer comprising at least one organic radical structure (nitroxyl group) of...
US-7,994,257 Downwell system with swellable packer element and composition for same
A composition suitable for use in a packer element for a wellbore includes: a hydrocarbon-swellable polymer, the hydrocarbon-swellable polymer present in the...
US-7,994,256 Gel compositions
Disclosed are four gel compositions that have improved properties over the prior art. These gels include elastosols, solid rubbery gels, UV cured gels and...
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