Detection and quantification of biomarkers via a piezoelectric cantilever
Quantification of a target analyte is performed using a single sample to which amounts of the target analyte are added. Calibration is performed as part of...
Methods of nucleic acid target capture
Methods for efficiently capturing a target nucleic acid from a sample by using a mixture that contains a capture probe specific for the target nucleic acid, the...
MN/CA IX and cancer prognosis
Herein disclosed are methods that are prognostic for neoplastic/preneoplastic disease in a subject vertebrate, wherein said disease is associated with a tissue...
Lysis reagent for use with capture-in-solution immunoassay
The invention provides a lysis reagent and method for preparing a test sample for use in an assay, wherein the method yields a homogeneous lysis mixture...
Method and probes for the detection of a tumor-specific fusion protein
The invention relates to the detection of fusion proteins. Described are a set of at least a first and a second molecular probe, each probe provided with a dye...
Human TIMP-1 antibodies
Human antibodies that bind to TIMP-1 can be used as reagents to diagnose and treat disorders in which TIMP-1 is elevated, such as liver fibrosis, alcoholic...
Staphylococcus protein A domain mutants that bind to TNF-.alpha.
A TNF-.alpha. binding polypeptide is provided, which is related to a domain of staphylococcal protein A (SPA) in that the sequence of the polypeptide...
Plasma or serum separation membrane and filter apparatus including the
plasma or serum separation membrane
A Plasma or serum separation membrane that enables omitting centrifugal separation, is free from hemolysis attributed to destruction of red blood cells and...
Probe, probe set, probe carrier, and testing method
A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The...
The invention is directed to purified and isolated novel ACPL polypeptides, the nucleic acids encoding such polypeptides, processes for production of...
Artificial chimeras engineered to simulate multiple biological threat
This invention provides safe, non-infectious chimeras that include the nucleic acid signature of most bacterial and viral biological threat agents. These...
Genetic polymorphisms in the prostate-specific antigen gene promoter
The present invention includes methods of identifying a subject at risk for increased cellular PSA production and/or prostate cancer by detecting the presence...
Directed enrichment of genomic DNA for high-throughput sequencing
The present invention provides microarrays of oligonucleotide primer pairs, and in particular, microarrays of primers that comprise at least one cleavable...
Method of screening for LRRK2-related parkinsonism inheritance
A polynucleotide consisting of the base sequence of SEQ ID NO: 2, or a complementary strand thereto, wherein the X is one of the group being defined by the...
Detection and/or quantification method of target molecules on a solid
The present invention relates to a method and device for detecting and/or quantifying one or multiple target molecules present in a solution by quantifying...
Methods and kits for reducing non-specific nucleic acid amplification
Methods and kits for efficient amplification of nucleic acids are provided. The methods comprise in-vitro amplification of a nucleic acid template employing...
Nucleic acid primers and probes for detecting human and avian influenza
Provided are nucleic acid sequences that are used to prepare primers and probes that are used in a kinetic polymerase chain reaction (kPCR) assay to detect...
Gene expression analysis using array with immobilized tags of more than 25
This invention provides a method of gene expression analysis that enables extensive gene expression analysis and simultaneous analysis of multiple samples of...
Genes affecting human memory performance
The present invention relates to DNA sequences associated with human memory performance. It also provides methods for (i) screening for diseases and...
BRCA2 mutations and use thereof
Genetic variants in the BRCA2 gene are disclosed which are useful as diagnosis biomarkers.
Detection of ErbB2 gene amplification to increase the likelihood of the
effectiveness of ErbB2 antibody breast...
The invention provides a method for more effective treatment of patients susceptible to or diagnosed with tumors overexpressing ErbB, as determined by a gene...
Genetic polymorphisms associated with psoriasis, methods of detection and
The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present...
Methods and compositions for diagnosing and monitoring the status of
transplant rejection and immune disorders
The invention presents methods of using splice variants and reagents thereof for diagnosing and monitoring the status of transplants and immune disorders...
Methods of normalization in microRNA detection assays
This application describes methods of quantifying a target miRNA in a biological sample by measuring the amounts of a target miRNA and at least one reference...
Prostate-specific gene for diagnosis, prognosis and management of prostate
Disclosed are nucleic acid and amino acid sequences encoded by a novel, prostate specific gene (UC41) and diagnostic techniques for the detection of human...
HPRP4s modifiers of the p53 pathway and methods of use
Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function....
PCR process and arrangement for DNA amplification using dry reagents
A PCR process for DNA amplification with thermocyclisation of the corresponding reagents is disclosed, in which total integration of all substances and process...
Procedure for the determination of fragmentation of DNA in animal sperm
The present invention describes a method for the determination of DNA fragmentation in animal sperm. It particularly refers to a procedure to evaluate the...
Method for analyzing blood for the presence of cancer cells
The present invention relates to a method for investigating body fluids for cancer cells, the use thereof and corresponding analysis kits, and the possibilities...
Detection of molecular probes fixed to an active zone of a sensor
The present invention relates to a method for detecting at least one parameter representative of molecular probes fixed to zones of a sensor.
Compositions and methods for determining the susceptibility of a
pathogenic virus to protease inhibitors
The present invention provides an approach for developing an algorithm for determining the effectiveness of anti-viral drugs based on a comprehensive analysis...
Biomarkers for toxic algae
The present invention is directed toward biomarkers that identify characteristics of algae. The invention is further directed toward biomarkers that serve to...
The present invention relates to a marker that can be used as aging biomarker. More specifically, the present invention relates to the analysis of N-glycans in...
Methods and apparatus for the isolation and enrichment of circulating
Embodiments in accordance with the present invention relate to methods and apparatuses for concentrating and isolating Circulating Tumor Cells (CTCs) from body...
Pattern manufacturing equipments, organic thin-film transistors and
manufacturing methods for organic thin-film...
A liquid film applicator means can apply a photosensitive lyophobic film 18 to a substrate 16. An exposure unit 10 is placed on the back side of the substrate...
Electrowetting display devices and fabrication methods thereof
Electrowetting display devices and fabrication methods thereof are presented. The electrowetting display device includes a first substrate and a second...
Optical disk manufacturing method
A method for manufacturing an optical disk having a middle layer on a substrate includes the steps of coating an ultraviolet curing resin over the substrate,...
Structure with self aligned resist layer on an insulating surface and
method of making same
A structure is provided with a self-aligned resist layer on an insulator surface and non-lithographic method of fabricating the same. The non-lithographic...
Method for fabricating self-aligned nanostructure using self-assembly
block copolymers, and structures...
In one embodiment, the present invention provides a method for patterning a surface that includes forming a block copolymer atop a heterogeneous reflectivity...
Line ends forming
Methods of forming line ends and a related memory cell including the line ends are disclosed. In one embodiment, the method includes forming a first device...
Method for forming patterns using single mask
A method for forming patterns using a single mask includes: disposing a photo mask having a defined pattern, and performing an exposure process by controlling...
Apparatus and method for conformal mask manufacturing
A manufacturing process technology creates a pattern on a first layer using a focused ion beam process. The pattern is transferred to a second layer, which may...
Calixarene blended molecular glass photoresists and processes of use
Photoresist compositions include a blend of at least one fully protected calixresorcinarene and at least one unprotected calixresorcinarene, wherein the...
Positive resist compositions and patterning process
A positive resist composition comprises (A) a resin component which becomes soluble in an alkaline developer under the action of an acid and (B) an acid...
(Meth)acrylate compound having aromatic acid labile group, photosensitive
polymer, resist composition, and...
A (meth)acrylate compound having an aromatic acid-labile group, the (meth)acrylate compound being represented by the following Formula 1: ##STR00001## In...
Photosensitive resin composition, photosensitive element, method for
forming resist pattern and method for...
A photosensitive resin composition comprising: (A) a binder polymer; (B) a photopolymerizable compound that has an ethylenically unsaturated bond; and (C1) a...
TARC material for immersion watermark reduction
A coating material disposed overlying a photo sensitive layer during an immersion lithography process includes a polymer that is substantially insoluble to an...
Compositions, systems, and methods for imaging
A composition, method, and system for recording an image. The system includes a multiphase imaging material in which energy is absorbed by an antenna material....
Transfer substrate, and fabrication process of organic electroluminescent
A transfer substrate is provided with a photothermal conversion layer and a transfer layer formed in this order on a base substrate. The transfer layer is...
Polyalkylene glycol benzoate containing photoconductors
A photoconductor that includes a supporting substrate, an optional ground plane layer, an optional hole blocking layer, a photogenerating layer, and at least...