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Patent # Description
US-7,999,105 Process for the preparation of 3-hydroxymorphinan derivatives
Processes are described for the synthesis of 3-hydroxymorphinan derivatives by hydrolysis of side products from the O-demethylation of 3-methoxymorphinan...
US-7,999,104 Methods for one-pot N-demethylation/N-acylation of morphine and tropane alkaloids
The present invention provides a method for the N-demethylation and/or N-acylation of an N-methylated heterocycle such as morphine alkaloids or tropane...
US-7,999,103 Metal complex compound and organic electroluminescence device using the compound
Provided are an organic electroluminescence device whose wavelength of light emission is short and which can emit blue light having a high color purity, and a...
US-7,999,102 Cross-linked cyclic amine compounds and agents for pest control
Cyclic amine compounds represented by formula (1) ##STR00001## or salts thereof or N-oxides thereof, wherein Cy.sup.1 represents an unsubstituted or...
US-7,999,101 Cationic lipids for the transfection of nucleic acids
The present invention relates to cationic lipids capable of forming complexes with nucleic acids and the use thereof for the transfection of eukaryotic cells....
US-7,999,100 Method for chiral inversion of (S)-(+)-and (R)-(-)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide...
A method for chiral inversion of optically pure or optically enriched mixtures of (S)-(+)-10,11-dihydro-10-hydroxy-5H-dibenz/b,f/azepine-5-carboxamide (I) ...
US-7,999,099 Modified 5'-phosphonate azidothymidine--potential anti-viral preparations
The invention relates to the field of molecular biology, virology and medicine and, more specifically, to novel derivatives of 3'-azido-3'-deoxythymidine...
US-7,999,098 Triphosphate oligonucleotide modification reagents and uses thereof
Hydrazino, oxyamino and carbonyl-based monomers and methods for incorporation into oligonucleotides during enzymatic synthesis are provided. Modified...
US-7,999,097 siRNA targeting beta secretase (BACE)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize...
US-7,999,096 Anti-myosin Va siRNA and skin depigmentation
The present invention relates to novel isolated siRNAs comprising a sense RNA strand and a complementary antisense RNA strand which together form an RNA duplex,...
US-7,999,095 Nucleic acid supported protein complementation
The present invention is directed to novel methods for in vitro and in vivo detection of target nucleic acid molecules, including DNA and RNA targets, as well...
US-7,999,094 Promoter molecules for use in plants
The present invention relates to polynucleotide molecules for regulating gene expression in plants. In particular, the present invention relates to promoters...
US-7,999,093 Nitrate transport components
This invention relates to isolated nucleic acid fragments encoding high affinity nitrate transport components. The invention also relates to the construction of...
US-7,999,092 Amplicon rescue multiplex polymerase chain reaction for amplification of multiple targets
Disclosed is a method for amplifying and detecting polynucleotides which can provide sensitive, specific detection of multiple targets from a clinical specimen...
US-7,999,091 5-methylcytosine detection, compositions and methods therefor
Compositions and methods for detecting 5-methylcytosine in a nucleic acid are disclosed. A 5-methylcytosine discriminator, which is a ...
US-7,999,090 Fungal cell wall synthesis gene
The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and...
US-7,999,089 RNA aptamers and the uses thereof
The present invention relates to RNA aptamers and uses thereof, more precisely RNA aptamers interfering the interaction of TCF with other proteins by binding...
US-7,999,088 Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes,...
The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid...
US-7,999,087 2'-silyl containing thiocarbonate protecting groups for RNA synthesis
Nucleoside monomers, nucleic acids, e.g., oligonucleotides and polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed...
US-7,999,086 Method of conditioning azo pigments containing carboxylic ester groups
The invention provides a method of conditioning azo pigments containing carboxylic ester groups, using glycol monoalkyl ethers or mixtures of glycols and glycol...
US-7,999,085 Enhanced capacity and purification of protein by mixed mode chromatography in the presence of aqueous-soluble...
This invention relates to the use of mixed mode chromatography for purification of a protein from a mixture containing other materials, including fragmented or...
US-7,999,084 Devices and methods for reducing matrix effects
Devices and methods are provided for reducing matrix effects in protein precipitated bioanalytical samples comprising: a support, and a sorbent associated with...
US-7,999,083 Immunoconjugates with an intracellularly-cleavable linkage
The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an...
US-7,999,082 Anti-factor B antibodies
Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such...
US-7,999,081 Anti-C5 alpha antibodies
The present invention refers to recombinant antibodies of human origin specific for the C5 component of the activated complement and characterised by the...
US-7,999,080 Reagents for the detection of protein phosphorylation in signaling pathways
The invention discloses novel phosphorylation sites identified in signal transduction proteins and pathways, and provides phosphorylation-site specific...
US-7,999,079 Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/A) and the epitopes bound by those antibodies. The...
US-7,999,078 Antibodies that bind DNAX leukocyte associated immunoglobulin-like receptor
Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are...
US-7,999,077 IRTA2 antibodies and methods of use
Antibodies that specifically bind the extracellular domain of IRTA2 are disclosed herein. In one embodiment, these antibodies do not specifically bind IRTA1,...
US-7,999,076 Use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or...
The present invention relates to the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing...
US-7,999,075 Methods for identifying compounds that regulate beta-arrestin signaling complexes
A method of screening a candidate compound for .beta.Arrestin mediated anti-G protein coupled receptor signaling activity is comprises: (a) contacting said...
US-7,999,074 Bacteriocins and novel bacterial strains
Novel bacteriocins produced by novel bacterial strains are used for at least reducing the levels of colonization by at least one target bacteria in animals,...
US-7,999,073 Modular transfection systems
The present invention relates to a method for transfection of cells using at least one protein capable of forming nucleoprotein filaments, wherein the protein...
US-7,999,072 Mutated netrin-4, fragments thereof and their use as medicines
Described is use of a netrin selected among netrin-4, mutated netrin-4, netrin-1, netrin G1 or netrin-3, or one of their fragments or a nucleotide sequence...
US-7,999,071 Human cytotoxic T-lymphoctye epitope and its agonist eptiope from the non-variable number of tandem repeat...
Novel MUC-1 epitopes outside the VNTR region are identified. In addition, the first agonist epitope of MUC-1 is described. The employment of agonist epitopes in...
US-7,999,070 Process for screening of a binding peptide specific for specific RNA and RNA binding peptides therefrom
The present invention relates to a screening method for RNA specific binding peptide using alpha-helical peptides. The screening method for RNA specific binding...
US-7,999,069 EphB receptor-binding peptides
The application is related to the identification of peptides that selectively bind to Eph receptors of the B class. Also disclosed are uses of such peptides in...
US-7,999,068 Process for the preparation of bicyclic peptide compounds
A new process for the preparation of bicyclic peptide compounds Formula (I) in high yields of high purity, useful as intermediates for preparing compounds with...
US-7,999,067 Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
The present invention is directed stromal cell derived factor-1 peptides that have been mutated to make them resistant to digestion by the proteases dipeptidyl...
US-7,999,066 Copper removal from ATRP products by means of addition of sulfur compounds
The present invention relates to a precipitation process for removing transition metals from polymer solutions. Specifically, it comprises the removal of...
US-7,999,065 Hydrophobically modified polyamine scale inhibitors
Hydrophobically modified Si-containing polyamines are useful for treating scale in industrial process streams. Preferred hydrophobically modified Si-containing...
US-7,999,064 Polyquaternium-1 synthesis methods and associated formulations
A multipurpose solution for contact lens care, comprising: an aqueous liquid medium; a quaternary ammonium polymer having an average molecular weight as...
US-7,999,063 Polyquaternium-1 synthesis methods and associated formulations
A multipurpose solution for contact lens care, comprising: an aqueous liquid medium; a quaternary ammonium polymer having an average molecular weight as...
US-7,999,062 Soluble polythiophene derivative
The invention discloses soluble polythiophene derivatives containing highly coplanar repeating units. The coplanar characteristic of side chain conjugated...
US-7,999,061 Catalytic lactide and glycolide (co)polymerization system
A catalytic lactide and glycolide copolymerization system comprising a trifluoromethane sulfonate as a catalyst and copolymerization additive and a...
US-7,999,060 Tailorable polyimide prepolymer blends, crosslinked polyimides, and articles formed therefrom
A tailorable polyimide prepolymer blend comprising an end group component, a dianhydride component, and a diamine component. The dianhydride component includes...
US-7,999,059 Optical film and method for production thereof
The invention relates to an optical film containing aromatic polymer which shows high solubility to solvents, and methods for production thereof. Further, the...
US-7,999,058 Method for producing aromatic polymer
A method for producing an aromatic polymer includes polycondensing an aromatic compound represented by formula (I) in the presence of a nickel complex...
US-7,999,057 Gas-phase process for the synthesis of diaminopyridines from glutaronitriles
A gas-phase, continuous process is provided for the manufacture of 2,6-diaminopyridine and related compounds from glutaronitriles, which are used industrially...
US-7,999,056 Continuous production method and production apparatus of aromatic polycarbonate
The object of the present invention is to provide a method of producing plural kinds of aromatic polycarbonates by a melt process without changeover loss and...
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