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Patent # Description
US-8,012,952 Cationic 17 .alpha.-substituted-estradiol derivatives useful as anti-cancer agent
The present invention provides a novel series of cationic, lipid-based, 17.alpha.-substituted-estradiol derivatives. The present invention further provides a...
US-8,012,951 7-N-substituted phenyl tetracycline compounds
7-substituted tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted...
US-8,012,950 Method to diagnose and treat degenerative joint disease
Disclosed are methods for detecting and treating joint disease. The methods of diagnosis include determining increased expression of enzymes that are...
US-8,012,949 Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS
The disclosure provides, inter alia, novel bisphosphonate compounds and methods of making and using such compounds. In certain embodiments, compounds of the...
US-8,012,948 Fas/FasL or other death receptor targeted methods and compositions for killing tumor cells
Provided herein are methods and compositions for killing tumor cells. In certain embodiments, compositions can promote apoptosis by down-regulating FAPP2 and...
US-8,012,947 Methods and compositions for promoting wound healing
Provided herein are compositions and methods that inhibit expression of Adam12 gene products, such as ADAM12 mRNA and/or ADAM12 polypeptides, as a therapeutic...
US-8,012,946 Anti-angiogenic methods and compositions
Disclosed herein are methods and compositions for treatment of conditions requiring inhibition of angiogenesis. Such conditions include those characterized by...
US-8,012,945 Phage antibodies to radiation-inducible neoantigens
A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing...
US-8,012,944 Method for treating cancer using IAP antisense oligomer and chemotherapeutic agent
The invention features methods, compositions, and kits for treating a patient having a proliferative disease.
US-8,012,943 Antibacterial agents
Described herein are novel macrolides, the preparation of novel macrolides, the use of novel macrolides for preventing, treating, or ameliorating various...
US-8,012,942 Carba-nucleoside analogs for antiviral treatment
Provided are thieno[3,4-d]pyrimidin-7-yl and furo[3,4-d]pyrimidin-7-yl ribosides, riboside phosphates and prodrugs thereof as well as intermediates and methods...
US-8,012,941 Carba-nucleoside analogs for antiviral treatment
Provided are imidazo[1,5-f][1,2,4]triazinyl, imidazo[1,2-f][1,2,4]triazinyl, and [1,2,4]triazolo[4,3-f][1,2,4]triazinyl nucleosides, nucleoside phosphates ...
US-8,012,940 Utilization of anti-neuropathic pain effect of D-allose and D-psicose
To control neuropathic pain produced by various mechanisms. Disclosed is a composition for elimination, relief or reduction of neuropathic pain comprising, as...
US-8,012,939 Macrocyclic inhibitors of hepatitis C virus
Inhibitors of HCV replication of formula (I) ##STR00001## and the N-oxides, salts, and stereoisomers thereof, wherein each variable has specific definitions....
US-8,012,938 Dermatological and/or cosmetic composition containing polypeptides
The present invention relates to the use of proteins of the UCP family, or UCP protein polypeptide or peptide fragments, as an active agent, alone or in...
US-8,012,937 Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
A novel gene 098P4B6 (also designated STEAP-2) and its encoded protein, and variants thereof, are described wherein 98P4B6 exhibits tissue specific expression...
US-8,012,936 Tau fragments for immunotherapy
The present invention relates to methods of treating and preventing Alzheimer's Disease or other tauopathies in a subject by administering a tau protein, its...
US-8,012,935 Synthetic peptides and methods for treating cancer invasion and metastasis
The present invention relates to synthetic oligopeptides that exhibit inhibitory activity towards cancer invasion and metastasis. The peptides of the invention...
US-8,012,934 Small peptides and methods for treatment of inflammation
Methods for treating cutaneous inflammation are described. Also described is a method for blocking IgE activation of a lymphocyte, a method for stabilizing the...
US-8,012,933 Use of the cathelicidin LL-37 and derivatives therof for wound healing
Use of the antimicrobial cathelicidin peptide II-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end,...
US-8,012,932 Contraceptives based on SP22 and SP22 antibodies
Oral, topical and injectable contraceptives, which are based on sperm protein 22 kDa (SP22) polypeptides and antibodies and infertility diagnostics are provided.
US-8,012,931 Modified FGF-21 polypeptides and their uses
Modified FGF-21 polypeptides and uses thereof are provided.
US-8,012,930 Methods of treating pervasive development disorders
A therapeutic method for treating an individual diagnosed with PDD pervasive developmental disorder comprises determining the efficacy of digestive enzyme...
US-8,012,929 Peptides directed for diagnosis and treatment of amyloid-associated diseases
Peptides having at least 2 amino acids and no more than 15 amino acids are provided. The peptides comprise amino acid sequence X-Y or Y-X, wherein X is an...
US-8,012,928 Truncated PAP2 and methods of making and using same
A method of treating pancreatitis is provided, including the steps of: providing a mammal having pancreatitis; and administering a therapeutically effective...
US-8,012,927 Platelet promoting protein and the usage thereof
The present invention discloses a protein that has strong affinity to thrombopoietin receptor (C-MPL) and the nucleotide sequences of the protein. The protein...
US-8,012,926 Amino acid composition and supplementary liquid containing the same
An amino acid composition comprises alanine, arginine, aspartic acid, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine,...
US-8,012,925 Agent for inducing apoptosis comprising MSX1 or a gene encoding the same as an active ingredient
The present invention relates to a novel use of Msx1 protein or a nucleotide encoding the same for inducing apoptosis. The Msx1 of the present invention induces...
US-8,012,924 Amino acid composition and supplementary liquid containing the same
An amino acid composition comprises alanine, arginine, aspartic acid, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine,...
US-8,012,923 Detergent composition
A detergent composition contains a polyglycerol monoalkyl ether, water, a fat or oil, and a polyol. The polyglycerol monoalkyl ether is present in the...
US-8,012,922 Wet cleaning solution
A wet cleaning solution, comprising 0.01-3 wt % of an amphoteric imidazolium surfactant capable of forming a complex with metal ions, a pH adjuster, and...
US-8,012,921 Composition for stripping photoresist and method for manufacturing thin transistor array panel using the same
The present invention provides a photoresist stripper including about 5 wt % to about 20 wt % alcohol amine, about 40 wt % to about 70 wt % glycol ether, about...
US-8,012,920 Lubricant for magnetic disks, method for producing the lubricant used in the magnetic disks, and method for...
The present invention provides a lubricant for forming a lubricating layer which is useful in preventing fly and stiction and/or corrosion at an extremely small...
US-8,012,919 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same
The present invention is directed to a lubricating oil composition, a diesel engine comprising a lubricating oil composition, and a method of lubricating a...
US-8,012,918 Detergent
An overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index of less than 2 and a degree of carbonation of 80% or greater is...
US-8,012,917 Crosslinked polymer
The present invention provides a lubricating composition comprising: (a) an oil of lubricating viscosity; and (b) a crosslinked polymer derived from monomers...
US-8,012,916 Phosphorus-molybdenum compound, method for producing same and lubricant additive and lubricant composition...
A lubricating oil additive capable of providing an antioxidant which enables a lubricating oil composition to have long drain intervals, while reducing specific...
US-8,012,915 Fuser fluid
The present invention is a release oil of the general formulae: ##STR00001## wherein (Z) is an amine. The solvent extracted portion of the release oil has a...
US-8,012,914 Ortho ester breakers for viscoelastic surfactant gels and associated methods
Many methods are provided including a method comprising: providing a surfactant gel having a first viscosity that comprises an aqueous base fluid and a...
US-8,012,913 Diamine terminated primary amine-aldehyde sulfur converting compositions and methods for making and using same
A new class of sulfur scavenging or converting compositions is disclosed comprising diamine terminated, amine-aldehyde adducts, where the adducts are...
US-8,012,912 Method of increasing the yield of sugar from sugarcane
A method of increasing the recoverable sugar content in sugarcane. The method comprises an efficient nitrogen fertilization practice, and a monitoring system to...
US-8,012,911 Methods to increase crop yield
Provided herein are exemplary methods for increasing crop yield. One exemplary method for increasing a yield of a crop includes controlling plant tissue stress...
US-8,012,910 Printing method using thermal diffusion transfer, and image formed object
There is provided a printing method that can provide an image formed object which can suppress a change in density of a visible dye image and a lowering in...
US-8,012,909 Heat-sensitive transfer image-forming method
An heat-sensitive transfer image-forming method which uses a heat-sensitive transfer image-receiving sheet and a heat-sensitive transfer sheet, in which the...
US-8,012,908 Heat-sensitive transfer image-receiving sheet and method of producing image
A heat-sensitive transfer image-receiving sheet, which is used in an image formation system that continuously produces printed outputs at intervals of 5 seconds...
US-8,012,907 Guanidinated polysaccharides, their use as absorbents and process for producing same
The present invention relates to cationic, gel forming, guanidinated polysaccharides of Formula I, their use as absorbent materials, and to processes for...
US-8,012,906 High-temperature catalytic material and method for producing the same
A high-temperature catalytic material and a method for producing the same are disclosed. The high-temperature catalytic material is obtained by subjecting a...
US-8,012,905 Process for preparing platinum based electrode catalyst for use in direct methanol fuel cell
A method for preparing platinum (Pt) based nano-size catalyst which is useful as an electrode catalyst of a direct methanol fuel cell (DMFC). This method...
US-8,012,904 Acid resistant ceramic materials, filter using the same, and preparation of them
The present invention provides porous ceramic materials having good resistance to heat, acid and base, comprising three or more oxides selected from an oxide of...
US-8,012,903 Methods to prepare catalyst compositions comprising small silica support materials
Methods are provided to prepare a catalyst system that includes at least one titanium compound, at least one magnesium compound, at least one electron donor...
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