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Patent # Description
US-8,026,379 Paricalcitol intermediates
The present invention relates to a compound and a novel process for the preparation of Paricalcitol intermediates.
US-8,026,378 Glyceryl ether compounds and their use
Glyceryl ether compounds prepared by the reaction of glycerol and olefin epoxides are disclosed. The compounds are renewable biomass-based surfactants useful as...
US-8,026,377 Process for (3R, 5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino)...
The present invention relates to processes for the manufacture of (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl...
US-8,026,376 Forms of [R-(R*,R*)]-2-(4-fluorophenyl)-.beta.,.delta.-dihydroxy-5-(1-meth- ...
Novel forms of [R-(R*,R*)]-2-(4-fluorophenyl)-.beta.,.delta.-dihydroxy-5-(1-methylethyl)- -3-phenyl-4 -[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi ...
US-8,026,375 Transition metal catalyzed synthesis of N-aminoindoles
The present invention relates to a process for the regioselective synthesis of compounds of the formula I, ##STR00001## wherein R0; R1; R2; R3; R4; R5; R6;...
US-8,026,374 Process for preparing (meth)acrylic esters of N-hydroxyalkylated imidazoles
A process for preparing (meth)acrylic esters (F) of N-hydroxyalkylated imidazoles, wherein N-hydroxyalkylated imidazoles (I), ##STR00001## in which R.sup.1...
US-8,026,373 1,2,3-triazole bound borane compounds, synthesis of, and use in reduction reactions
A 1,2,3-triazole coordinated borane such as ##STR00001## where the B and the R.sup.3 groups can be on any of the three N positions and R.sup.1, R.sup.2,...
US-8,026,372 Process for the preparation of .epsilon.-alkoxycarbonyllysines and their analogues
A process for the preparation of .omega.-alkoxycarbonylamino-.alpha.-aminoacids and .alpha.,.omega. orthogonally diprotected diaminoacids from...
US-8,026,371 Hydroxamates as therapeutic agents
The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of...
US-8,026,370 Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof
According to the present invention, a compound represented by the following formula (I) having a superior PPAR.sub..alpha. agonist action and concurrently...
US-8,026,369 Composition containing thiazole rings, organic semiconductor polymer containing the composition, organic active...
Disclosed herein is a composition containing hetero arylene or arylene showing a p-type semiconductor property in addition to thiophene showing a p-type...
US-8,026,368 Hydrazide compounds and thrombopoietin receptor activators
Compounds effective for preventing, treatment or improving diseases against which activation of the thrombopoietin receptor is effective are provided. A...
US-8,026,367 (R)-arylalkylamino derivatives and pharmaceutical compositions containing them
The present invention relates to selected (R)-arylalkylamino derivatives of formula (I), in which R, R1 and Ar are as defined in the claims. These compounds...
US-8,026,366 Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
Thiazoloquinoline and thiazolonaphthyridine compounds having an aryloxy or arylalkyleneoxy substituent at the 6-, 7-, 8-, or 9-position, pharmaceutical...
US-8,026,365 4,4-disubstituted piperidine derivatives
This invention relates to 4,4-disubstituted piperidine derivatives of the formula ##STR00001## wherein A and R.sup.1 to R.sup.5 are as defined in the...
US-8,026,364 NK.sub.1 antagonists
A compound having the general structure shown in Formula I: ##STR00001## or pharmaceutically acceptable salt and/or solvates thereof are useful in treating...
US-8,026,363 Process for producing coelenteramide or an analog thereof
A process for producing coelenteramide or its analog in a high yield has been desired. The invention provides a process for producing di-O-methylcoelenteramide...
US-8,026,362 Non-nucleoside reverse transcriptase inhibitors
Compounds of formula I, wherein R.sup.1, X.sup.1, X.sup.2 and A, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse...
US-8,026,361 Isoindoline pigments
Isoindoline pigments of the general formula I ##STR00001## in which the variables are defined as follows: R.sup.1 is C.sub.1-C.sub.4-alkyl; R.sup.2 is...
US-8,026,360 Substituted pyridazines as stearoyl-CoA desaturase inhibitors
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal...
US-8,026,359 Fungicidal heterocyclic amines
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, ##STR00001## wherein R.sup.1, R.sup.2, R.sup.9a, R.sup.9b, G, W, X, Y, and Z are as...
US-8,026,358 Process for preparing porphyrin derivatives, such as protoporphyrin (IX) and synthesis intermediates
The present invention relates to a process for preparing a porphyrin of formula (I), optionally in the form of a salt with an alkali metal and/or in the form of...
US-8,026,357 Cellulose acylate film and its applications
A cellulose acylate film, comprising a cellulose acylate having at least one substituent (Substituent A) comprising an aromatic group having at least one C4 or...
US-8,026,356 Process for the large scale production of Stavudine
The present invention provides a method for preparing pure Stavudine having purity more than 99.5% comprises: i) Converting 3',5'-anhydrothymidine to crude...
US-8,026,355 Oligomeric compounds for the modulation of survivin expression
Oligonucleotides directed against the survivin gene are provided for modulating the expression of survivin. The compositions comprise oligonucleotides,...
US-8,026,354 Recombinant plasmodium falciparum merozoite surface proteins 4 and 5 and their use
Accordingly, the invention provides constructs in which the nucleic acids encoding Plasmodium falciparum MSP4 and MSP5, and the resulting polypeptides, have...
US-8,026,353 Nucleic acid molecules encoding human 4-1BB
The human receptor H4-1BB has been isolated, sequenced and disclosed herein. The cDNA of the human receptor H4-1BB is about 65% homologous to the mouse cDNA...
US-8,026,352 Methods for determining the presence or absence of elite event RF-BN1 in Brassica plant material
This invention relates to transgenic winter oilseed rape (WOSR) plants, plant material and seeds, harboring a specific transformation event. It pertains to...
US-8,026,351 Monocyte-derived nucleic acids and related compositions and methods
Nucleic acids encoding various monocyte-derived proteins and related compositions, including purified proteins and specific antibodies are described. Methods of...
US-8,026,350 Tumor suppressor gene, p28ING5
This disclosure provides a novel tumor suppressor, referred to as p28ING5, nucleic acid molecules encoding this protein, and methods of making and using these...
US-8,026,349 Polynucleotide synthesis labeling chemistry
Methods and compositions for making nucleoside phosphoramidites and nucleic acids, including mono-, di-, and polynucleotides, comprising a linker covalently...
US-8,026,348 Nucleoside derivative, modified oligonucleotide, method for their synthesis and applications thereof
Compositions and methods of preparing carboranes and metallacarboranes, which can be used as a new type of electrochemically active label for biological...
US-8,026,347 Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors
Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of...
US-8,026,346 Tribonectins
The invention features a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured or arthritic joint.
US-8,026,345 Characterization and identification of unique human adiponectin isoforms and antibodies
The invention pertains to methods for measuring different forms of human adiponectin that are present in human plasma/serum, and more specifically methods are...
US-8,026,344 Targeted binding agents directed to uPAR and uses thereof
Targeted binding agents directed to the antigen uPAR and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the...
US-8,026,343 Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion...
The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the...
US-8,026,342 Compositions and methods for binding sphingosine-1-phosphate
The present invention relates to anti-S1P agents, for example, humanized monoclonal antibodies, and their uses for detection of S1P or for treatment of diseases...
US-8,026,341 Transfection complexes
The invention provides a peptide having at least 3 amino acids comprising an amino acid sequence selected from TABLE-US-00001 a) X.sup.1SM [SEQ.ID.NO.:...
US-8,026,340 High shear oxidation of wax
In this disclosure, a system is described, comprising a shear device with at least one inlet and at least one outlet and a mixing vessel with at least one inlet...
US-8,026,339 Polysulfone, electrolyte membrane using the same, and fuel cell using the electrolyte membrane
A polysulfone is provided with a nitrogen-containing functional group having an affinity to an acid, an electrolyte membrane using the polysulfone, and a fuel...
US-8,026,338 Method for producing polyimide film
A method for producing a polyimide film comprises the steps of: preparing a polar organic solvent solution of a polyimide precursor obtained by mixing a...
US-8,026,337 Production of a functionalized polytriazole polymer
A method for the production of a functionalized polytriazole polymer, particularly a poly(1,2,4-triazole)-polymer, includes the steps of (a) mixing a hydrazine...
US-8,026,336 Polycarbonate resin composition and method of producing the same
The present invention relates to a polycarbonate resin composition which comprises a polycarbonate resin having the repeating unit that is represented by the...
US-8,026,335 Baked resin product and electronic device comprising the same
The present invention provides a baked resin product that exhibits an excellent heat resistance and an electronic device that incorporates this baked resin...
US-8,026,334 Polyurea and polyurethane compositions for golf equipment
Golf equipment having improved cut and shear resistance that includes a polyurea composition, preferably saturated and/or water resistant, formed of a polyurea...
US-8,026,333 Protected air-activated organotin catalysts for polyurethane synthesis and processes therefore
This invention relates to a protected organotin-based catalyst system for polyurethane synthesis that is useful in coatings applications. The catalyst has a...
US-8,026,332 Sealing material for optical element and sealed optical element
A sealing material for optical elements with excellent transparency, crack resistance, and heat resistance which can produce a cured product of the sealing...
US-8,026,331 Polymers made from polyhedral oligomeric silsesquioxanes and diacetylene-containing compounds
A compound having the formula below. Each R is methyl or phenyl; R.sup.2 comprises one or more of silane, siloxane, and aromatic groups; n is a nonnegative...
US-8,026,330 Organopolysiloxane having carboxyl groups
An organopolysiloxane represented by the following average compositional formula (1): R.sup.1.sub.aR.sup.2.sub.bR.sup.3.sub.cSiO.sub.(4-a-b-c)/2 (1) wherein...
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