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Patent # Description
US-8,067,184 Optoelectronic detection system
The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins...
US-8,067,183 Methods and compositions for development of drug screening procedures and diagnostic tools
This invention defines novel research methodology for use in (a) monitoring the ongoing status of the physiological expression of Charcot-Marie-Tooth disease...
US-8,067,182 Method of weak partitioning chromatography
This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more...
US-8,067,181 MELKS as modifiers of the Rac pathway and methods of use
Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods...
US-8,067,180 MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use
Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with...
US-8,067,179 Immunoglobulin libraries
Methods and compositions for the screening and isolation of ligand-binding polypeptides, such as antibodies. In some aspects, methods of the invention enable...
US-8,067,178 Gene expression markers for prediction of patient response to chemotherapy
The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In...
US-8,067,177 Amplification methods
Methods are provided for amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection...
US-8,067,176 Microchemistry reaction method
A chemical reaction is conducted in a fluid of a droplet inside a reaction receptacle or on a surface of a reaction substrate. Fluctuations of a magnetic field...
US-8,067,175 Methods and compositions for detecting a drug resistant EGFR mutant
Polymerase chain reaction primers and methods directed to detecting the EGFR mutant C.fwdarw.T at the position corresponding to base 2369 of EGFR cDNA. The...
US-8,067,174 Polymerase chain reaction (PCR) method for amplifying a DNA template
The present invention relates to a DNA polymerase immobilized by covalent bonding. More particularly, the present invention relates to an immobilized DNA...
US-8,067,173 Method of profiling gene expression in a healthy subject
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of...
US-8,067,172 Device, kit and method for pulsing biological samples with an agent and stabilising the sample so pulsed
The present invention is related to a device, kit and method for pulsing a biological sample with a pulsing agent and subsequently stabilizing the biological...
US-8,067,171 Methods and compositions for improved fertilization and embryonic survial
Single nucleotide polymorphic site at position 11646 of the bovine FGF2 gene is associated with improved fertilization rate and/or improved embryo survival...
US-8,067,170 Binding method and apparatus for sorting objects
The present invention relates to a method and apparatus of sorting objects including, providing a sample having wanted objects and unwanted objects; coating a...
US-8,067,169 Detection of macromolecular complexes on ultraflat surfaces with harmonic cantilevers
Method and apparatus which uses harmonic cantilevers, such as used in atomic force microscopy, to detect variations in the attractive and repulsive forces on a...
US-8,067,168 Gene methylation in cancer diagnosis
The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The...
US-8,067,167 Hybrid antibodies
Hybrid antibodies and/or hybrid antibody fragments and methods of making them are provided. In one embodiment the hybrid antibodies and/or hybrid antibody...
US-8,067,166 Chromosome 1p36 polymorphisms and low bone mineral density
The invention provides methods and compositions for diagnosing risk of low BMD and risk of osteoporosis based on the detection of SNP identity for human...
US-8,067,165 Binary probe and clamp composition and methods for target hybridization detection
Binary probe and clamp compositions conduct methods for target hybridization detection. Where the probe is a substrate for exonuclease cleavage, the composition...
US-8,067,164 Microarray system with improved sequence specificity
The invention provides a novel array method for nucleic acid sequence detection with improved specificity which allows for detection of genetic variation, from...
US-8,067,163 Determination of the biological function of a target gene in a cell
Disclosed herein is a method to determine the biological function(s) of a target gene in a cell, the steps of which involve separately culturing a first...
US-8,067,162 Primer, primer set, and nucleic acid amplification method and mutation detection method using the same
The present invention provides a primer that effectively can detect, for example, the double helix structure of a nucleic acid. The primer is a labeled nucleic...
US-8,067,161 Dopaminergic neuron proliferative progenitor cell marker Nato3
The present invention is a probe, a primer, and an antibody, for detecting a dopaminergic neuron proliferative progenitor cell. According to the present...
US-8,067,160 Genetic markers of schizophrenia
The invention includes method of determining if a subject has a genetic predisposition to clinically diagnosed schizophrenia (SZ), schizotypal personality...
US-8,067,159 Methods of detecting amplified product
A microfluidic device comprising a first surface portion and a first sample retaining element, which have differing affinities to a fluid, and a method...
US-8,067,158 Methods and compositions for the diagnosis and treatment of schizophrenia
Compositions and methods relating to the diagnosis and treatment of neuropsychiatric disorders, such as schizophrenia, schizoaffective disorders, and bipolar...
US-8,067,157 Expression cloning in filamentous fungi
Methods are provided for isolation of DNA sequences encoding proteins with properties of interest by means of expression cloning in filamentous fungal host...
US-8,067,156 Method for generating replication defective viral vectors that are helper free
Sequences are provided that are capable of directing circular adeno-associated virus replication, useful in vectors for providing therapeutic agents to a...
US-8,067,155 Receptor tyrosine kinase assays
Methods for detecting phosphorylation of receptor tyrosine kinases ("RTKs") upon activation are provided. The method employs cells comprising two fusion...
US-8,067,154 Method and device for rapid detection of microorganisms by changing the shape of micro-colonies in micro-channels
This invention describes a method of rapid detection of micro-colonies of microorganisms by changing their shape from a regular semi-sphere to a long and thin...
US-8,067,153 Genes and polypeptides relating to prostate cancers
The present application provides novel human gene ELOVL7 whose expression is markedly elevated in prostate cancers. The gene and polypeptide encoded by the gene...
US-8,067,152 Liver cancer biomarkers
A method of detecting whether a subject is afflicted with or at increased risk of developing liver cancer is carried out by detecting cleavage of a marker in a...
US-8,067,151 Cold storage of pegylated platelets at about or below 0.degree. C.
A method for storing and using platelets and an associated platelet structure. At least one modified platelet is formed. Each modified platelet includes a...
US-8,067,150 In-situ preservation (ISP) bridge method and solution for non-heart beating donors
A method for rapid, in-situ flushing of organs of a non-heart beating donor, and solutions for carrying out the flushing, are provided. The method initiates...
US-8,067,149 Acellular dermal matrix and method of use thereof for grafting
A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing...
US-8,067,148 Pattern forming method
A resist film of a positive type containing a photoacid generator is formed on a substrate. Then, pattern exposure is performed by selectively irradiating the...
US-8,067,147 Removable pellicle for immersion lithography
A method of irradiating to pattern a photosensitive layer such as a resist (L2) immersed in a fluid (L3), involves applying a removable transparent layer (L4,...
US-8,067,146 Method for forming a fine pattern in a semicondutor device
A method for forming a fine pattern a semiconductor device includes the steps of forming a first photoresist pattern over a semiconductor substrate having an...
US-8,067,145 Developing solution and method for producing lithography printing plate
A developing solution includes at least one of a compound represented by formula (I) and a compound represented by formula (II) and being at pH 2 to 10: ...
US-8,067,144 Polyesters for toner for electrophotography
The present invention relates to a polyester having an excellent hydrolysis resistance even when used in a process for producing a toner for electrophotography...
US-8,067,143 Functional particle and manufacturing method thereof
A functional particle is manufactured by a method including an aggregating step, a depressurizing step, and a cooling step. In the aggregating step, the...
US-8,067,142 Coating, system and method for conditioning prints
Disclosed herein is a xerographic print comprising a substrate having a printed image thereon comprising a low melt temperature toner, and a polyolefin wax...
US-8,067,141 Electrographic carrier, developer, developing method, image forming apparatus, and process cartridge
A carrier is provided including a core and a resin layer located overlying the core, wherein the carrier has a weight average particle diameter (Dw) of from 22...
US-8,067,140 Toner for developing electrostatic image and method of producing the same
A toner for developing electrostatic image which has a reduced residual amount of a decomposed product of a polymerization initiator remaining in the toner upon...
US-8,067,139 Resin mixture backing layer containing photoconductor
A photoconductor that includes, for example, a backing layer, a supporting substrate, a photogenerating layer, and a charge transport layer, and where the...
US-8,067,138 Pyrrole containing photoconductors
A photoconductor that includes, for example, a supporting substrate, a photogenerating layer, and a charge transport layer, and wherein at least one of the...
US-8,067,137 Polymer containing charge transport photoconductors
A photoconductor that includes a supporting substrate, a photogenerating layer, and at least one charge transport layer that contains at least one charge...
US-8,067,136 Charge control agent, toner, image forming method, and image forming apparatus
To provide: a charge control agent having negative chargeability, which contributes to environmental conservation and the like to an increased degree, has high...
US-8,067,135 Metrology systems and methods for lithography processes
Metrology systems and methods for lithography processes are disclosed. In one embodiment, a method of manufacturing a semiconductor device includes providing a...
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