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Patent # Description
US-8,067,033 Stable compositions of famotidine and ibuprofen
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core...
US-8,067,032 Method for preparing submicron particles of antineoplastic agents
The present invention is concerned with the formation of submicron particles of an antineoplastic agent, particularly paclitaxel, by precipitating the...
US-8,067,031 Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
Crosslinkable compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The composition contains at least two biocompatible,...
US-8,067,030 Controlled release composition and method of producing the same
A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable...
US-8,067,029 Rapidly disintegrating gelatinous coated tablets
The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed...
US-8,067,028 Drug delivery device
Drug delivery devices are provided herein including crosslinked polymeric compositions. The devices may, in embodiments, possess at least two drug release...
US-8,067,027 Tissue augmentation material and method
A material and method for augmenting soft tissue. The tissue augmentation material consists essentially of water and a polysaccharide gel former selected from...
US-8,067,026 Drug release regions for medical devices, which include polycyclic-structure-containing polymers
According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain polymeric release regions that control...
US-8,067,025 Nitric oxide generating medical devices
Medical devices having a catalyst capable of catalyzing the generation of nitric oxide attached to the medical device and methods of treating a vascular...
US-8,067,024 Medical devices to prevent or inhibit restenosis
Implantable medical devices having anti-restenotic coatings are disclosed. Specifically, implantable medical devices having coatings of certain...
US-8,067,023 Implantable medical devices incorporating plasma polymerized film layers and charged amino acids
An implantable medical device, such as a stent, is disclosed comprising an amino acid or a polypeptide bonded to a plasma polymerized film layer formed on the...
US-8,067,022 Therapeutic inhibitor of vascular smooth muscle cells
Methods are provided for inhibiting stenosis following vascular trauma or disease in a mammalian host, comprising administering to the host a therapeutically...
US-8,067,021 Methods and compositions for delivery of growth factor to fibrous connective tissue
The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a...
US-8,067,020 Sustained release formulation
A composition comprises a protein, a polyol, and a metal. The protein is stabilized by the polyol and the metal, and is protected from denaturing when in...
US-8,067,019 Wax treated burnable dispensing substrates
Disclosed herein are burnable air treatment chemical dispensing substrates, such as mosquito coils, in which wax is incorporated. In one form the wax portion is...
US-8,067,018 Microencapsulated pyrethrin
A microcapsule comprising a core material containing pyrethrin and a capsule shell wall which surrounds said core material, said shell wall material comprises...
US-8,067,017 Preservation of bioactive materials by freeze dried foam
This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and...
US-8,067,016 Fusion proteins of Mycobacterium tuberculosis
The present invention relates to fusion proteins containing at least two Mycobacterium species antigens. In particular, it relates to nucleic acids encoding...
US-8,067,015 Methods and compositions for the treatment and prevention of Staphylococcus and other bacterial infections
The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, certain species of bacteria,...
US-8,067,014 Chimeric AAV capsid proteins
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a...
US-8,067,013 Multivalent avian influenza vaccines
A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at...
US-8,067,012 Treatment of melanoma using HSV mutant
Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the .gamma.34.5 gene in the long repeat region...
US-8,067,011 Compositions and methods for treating B-cell malignancies
The present invention provides a targeted multi-layered drug delivery system for the delivery of cytotoxic agents to B-cells.
US-8,067,010 Immunological herpes simplex virus antigens and methods for use thereof
The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent...
US-8,067,009 Metalloproteinase oligopeptides and their therapeutic use
The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides and peptidomimetics. The oligopeptides are used for making...
US-8,067,008 Peptide inhibitors for mediating stress responses
The present invention relates to peptides capable of inhibiting cellular and immune stress responses in a eukaryotic cell. The invention provides compositions...
US-8,067,007 Compositions and methods for identifying and targeting cancer cells of alimentary canal origin
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of...
US-8,067,006 Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
The present invention concerns methods and compositions for delivery of therapeutic agents to target cells, tissues or organisms. In preferred embodiments, the...
US-8,067,005 Divalent antibody fragments
Divalent antibody fragments are described, each of which has one or more interchain bridges containing a synthetic or naturally occurring polymer selected from...
US-8,067,004 Surface antigen
The invention provides a novel surface polypeptide from Neisseria meningitidis as well as nucleic acid and nucleic acid sequence homologues encoding this...
US-8,067,003 Methods of treating conditions using anti-IL-6 antibodies
Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic...
US-8,067,002 Humanized anti-factor D antibodies
The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor...
US-8,067,001 Antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
An antibody of the invention interacts with human DR5 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell...
US-8,067,000 Cancer treatment with endothelin receptor antagonists
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically, the present...
US-8,066,999 PEGylated A.beta. fab
A method to treat conditions associated with A.beta. peptide activity both prophylactically and therapeutically is described. The method employs humanized...
US-8,066,998 Antibodies for norovirus
Norovirus antigen peptides are described having an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-16, or fragments thereof. Such...
US-8,066,997 Modulation of activity of neurotrophins
The present invention relates to methods for modulating the activity of one or more neurotrophins, such as neural growth factor (NGF), brain derived...
US-8,066,996 Anti-CCR7 receptor antibodies for the treatment of cancer
Antibodies, or antigen-binding fragment thereof, which bind to a CCR7 receptor are capable of selectively killing, impairing migration and/or blocking...
US-8,066,995 Anti-myostatin antibodies
Anti-myostatin antibodies are identified that are characterized as having high affinity and may be chimeric, humanized or fully human antibodies, ...
US-8,066,994 Proteins comprising an IgG2 domain
Disclosed are methods and compositions for efficiently expressing antibody fusion proteins. Antibody fusion proteins of the invention include a hybrid antibody...
US-8,066,993 Use of ventricular enlargement rate in intravenous immunoglobulin treatment of Alzheimer's disease
The present invention relates to the use of MRI monitoring of ventricular enlargement rate as an objective measure for the purpose of assessing disease...
US-8,066,992 Medicament and a method of treating a pathological syndrome
A medicament based on antibodies contains an activated form of monoclonal, polyclonal, or natural antibodies to interferon in low or ultra-low doses prepared by...
US-8,066,991 Enzyme inhibitors of PAI-1
The invention provides a method for the treatment of a subject suffering from a cardiovascular disease using a therapeutically effective amount of at least one...
US-8,066,990 Lysin protein having broad antibacterial activity specific to bacteria
The present invention relates to a lysin protein originated from bacteriophage, more precisely a lysin protein comprising the amino acid sequence represented by...
US-8,066,989 Method of treating tumor growth and metastasis by using trifunctional antibodies to reduce the risk for GvHD in...
The present invention refers to a method of treating tumor growth and metastasis in a mammal, the treating comprising administering allogeneic effector cells...
US-8,066,988 In-hive trap and lure for control of the small hive beetle, Aethina tumida
A Small Hive Beetle trap, which replaces the bottom board of beehives, includes a frame having three walls and a top surface, a trap plate, an entry means, and...
US-8,066,987 Bacterial delivery of biologically active polypeptides
The present invention relates to methods for the delivery of biologically active polypeptides to a subject by colonizing non-pathogenic Gram negative bacteria....
US-8,066,986 Formulations including digestive enzymes and polysorbate surfactants that enhance the colonization of...
Disclosed are formulations for enhancing the in vivo colonization of probiotic microorganisms that include digestive enzymes and probiotic microorganisms, and...
US-8,066,985 Reovirus for the treatment of cellular proliferative disorders
Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so...
US-8,066,984 Modified vaccinia virus strains for use in diagnostic and therapeutic methods
Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods...
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