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Patent # Description
US-8,071,380 Skeletal muscle periangioblasts and cardiac mesangioblasts, method for isolation and uses thereof
The present invention discloses the isolation and characterization of cells isolated either from adult skeletal muscle or from adult cardiac muscle. These cells...
US-8,071,379 Methods of tissue engineering
An improved substrate for growing mono-layers of adherent-type cells and methods of growing tissue structures, ex vivo. The improved substrate, which comprises...
US-8,071,378 ZNF206: regulator of embryonic stem cell self-renewal and pluripotency
We have identified ZNF206, a novel repressor of human embryonic stem cell (hESC) differentiation. Repressing extra-embryonic endoderm development preserves the...
US-8,071,377 Methods for immortalizing cells
The present invention provides methods for immortalizing precursor cells that are non-terminally differentiated cells such as stem cells, said methods...
US-8,071,376 Production of oligodendrocytes from placenta-derived stem cells
The present invention provides methods and compositions for the production of glial cells and oligodendrocytes from placenta stem cells. The invention further...
US-8,071,375 Use of IL-6-type cytokines for maturation of oocytes
The use of certain IL-6-type cytokines for the in vitro maturation of mammalian oocytes is described. The in vitro matured oocytes may be used in in vitro...
US-8,071,374 Methods for preparing T-cells for cell therapy
T-cells are generated with enhanced immunostimulatory capabilities for use in self therapy treatment protocols, by utilizing a biodegradable device with a...
US-8,071,373 Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)
The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising T cells, B...
US-8,071,372 Tumor endothelial marker 5.alpha. molecules and uses thereof
The present invention provides Tumor Endothelial Marker 5.alpha. (TEM5.alpha.) polypeptides and nucleic acid molecules encoding the same. The invention also...
US-8,071,371 Monoclonal antibody production by EBV transformation of B cells
A method for producing a clone of an immortalized human B memory lymphocyte, comprising the step of transforming human B memory lymphocytes using Epstein Barr...
US-8,071,370 Targeted modification of chromatin structure
Methods and compositions for targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and...
US-8,071,369 Compositions for reprogramming somatic cells
The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes,...
US-8,071,368 Methods for promoting growth and survival of insulin-secreting cells
The present invention relates to compositions containing unacylated ghrelin and derivatives thereof and their uses in the control of glycemia in ageing...
US-8,071,367 Selecting, culturing and creating lineage committed hematopoietic stem cells
The present invention provides a method for selecting hematopoietic stem cells (HSCs) comprising providing an agent which binds to .alpha.9.beta.1 integrin on...
US-8,071,366 Neural progenitor cells derived from whole bone marrow
A method is described for generating a clinically significant volume of neural progenitor cells from whole bone marrow. A mass of bone marrow cells may be grown...
US-8,071,365 Psod expression units
The present invention relates to the use of nucleic acid sequences for regulating the transcription and expression of genes, the novel promoters and expression...
US-8,071,364 Gene therapy using transposon-based vectors
Methods and compositions are presented for the administration of transposon based vectors to an animal or human to provide gene therapy to the animal or human.
US-8,071,363 Chip for cell electrophysiological sensor, cell electrophysiological sensor using the same, and manufacturing...
A chip for a cell electrophysiological sensor has a substrate. The substrate has a through-hole formed from the upside to the downside, and the opening of the...
US-8,071,362 Sterilization indicator
The disclosed technology relates to a sterilization indicator and a process to concentrate signal generated by constraining it to a minimal surface, in a...
US-8,071,361 Semiconductor nanocrystal probes for biological applications and process for making and using such probes
A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1)...
US-8,071,360 Semiconductor nanocrystal probes for biological applications and process for making and using such probes
A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1)...
US-8,071,359 Semiconductor nanocrystal probes for biological applications and process for making and using such probes
A semiconductor nanocrystal compound and probe are described. The compound is capable of linking to one or more affinity molecules. The compound comprises (1)...
US-8,071,358 Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino...
The present invention is directed to recombinant microorganisms comprising one or more dihydroxyacid dehydratase (DHAD)-requiring biosynthetic pathways and...
US-8,071,357 Yeast and method of producing L-lactic acid
Yeast includes an introduced gene coding a Homo sapiens- or frog-derived L-lactate dehydrogenase. It is possible to produce lactic acid, which has a variety of...
US-8,071,356 Salmonella enterica strains of reduced pathogenicity, method for their preparation and uses thereof
The invention concerns novel Salmonella enterica attenuated strains, characterized in that they are inactivated at the level of the znuABC operon through...
US-8,071,355 Polyhydroxyalkanoate production by coenzyme A-dependent aldehyde dehydrogenase pathways
Organisms are provided containing genes encoding one or more enzymes, Coenzyme-A-dependent aldehyde dehydrogenase, acyl-CoA transferase, acyl-CoA synthetase,...
US-8,071,354 Method of producing rough strains of bacteria and uses thereof
The present invention relates to a method of producing rough strains of a bacterium, such as Mycobacterium obuense, said method comprising exposing said...
US-8,071,353 Genetic remodeling in Bifidobacterium
A Bifidobacterium comprising a genome that is customized so as to lack an operable functional gene is disclosed. A method of making such cells is also...
US-8,071,352 Bacteriophage having killing activity specific to Staphylococcus aureus
The present invention relates to a novel bacteriophage, more precisely a novel bacteriophage having killing activity specific to Staphylococcus aureus which is...
US-8,071,351 Family 44 xyloglucanases
The present invention relates to xyloglucanases belonging to family 44 of glycosyl hydrolases and having a relative xyloglucanase activity of at least 30%...
US-8,071,350 Amylases, nucleic acids encoding them and methods for making and using them
In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using...
US-8,071,349 BGL4 beta-glucosidase and nucleic acids encoding the same
The present invention provides a novel .beta.-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention...
US-8,071,348 Protein tyrosine phosphatase substrate-trapping double mutant and uses thereof
The present invention provides protein tyrosine phosphatases (PTP) in which the invariant aspartate residue and the invariant glutamine residue are each...
US-8,071,347 Ketoreductases and uses thereof
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme....
US-8,071,346 System for the mitigation of photodamage in analytical reactions
Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or...
US-8,071,345 Stabilized subtilisin composition
The present invention relates to a liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer that is 3-chlorobenzoic acid,...
US-8,071,344 Site specific incorporation of keto amino acids into proteins
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and...
US-8,071,343 Process for producing glycolic acid from formaldehyde and hydrogen cyanide
A process is provided for producing glycolic acid from formaldehyde and hydrogen cyanide. More specifically, heat-treated formaldehyde and hydrogen cyanide are...
US-8,071,342 Process for the treatment of methane emissions
The invention relates generally to a system and method for the treatment of gaseous emissions comprising methane, and in one specific embodiment, to a system...
US-8,071,341 Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and...
US-8,071,340 Biocatalytic process for the production of ortho-aminophenols from chloramphenicol and analogs
A process for the production of ortho-aminophenolic analogs of chloramphenicol using a biocatalyst consisting of pure enzymes, partially purified enzymes, cell...
US-8,071,339 Mutant phosphoribosylpyrophosphate synthetase and method for producing L-histidine
The present invention relates to a mutant bacterial PRPP synthetase which is resistant to feedback by purine nucleotides, and a method for producing L-histidine...
US-8,071,338 Suppression of amplification using an oligonucleotide and a polymerase significantly lacking 5'-3' nuclease...
Methods and compositions for amplification of a target sequence by suppressing amplification of related sequences are provided.
US-8,071,337 Method for detecting viable cells in a sample by using a virus
A method for detecting viable cells such as bacterial cells, within a sample, said method comprising (i) incubating said sample with a virus which is able to...
US-8,071,336 Antibody-based therapeutics with enhanced ADCC activity
Methods for producing antibody-based therapeutics with enhanced ADCC activity are disclosed. The enhanced ADCC activity is attributed to oligomannose-type...
US-8,071,335 Polypeptides having acetylxylan esterase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having acetylxylan esterase activity and isolated polynucleotides encoding the polypeptides. The...
US-8,071,334 Preparation of soluble N-protein/truncated P-protein complexes of the paramyxoviridae family
The invention relates to a method for preparation of soluble N-protein/truncated P-protein complex of a virus of the family Paramyxoviridae, complexes prepared...
US-8,071,333 Anti-integrin antibodies, compositions, methods and uses
The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V...
US-8,071,332 Recombinant mammal cells, method of producing thereof, and method of producing proteins of interest
The present invention relates to a method of expressing an objective protein at a high level and stably as well as for a long period even in the absence of a...
US-8,071,331 Method of producing amino acid metal chelates
A method of producing amino acid metal chelates includes producing an amino acid ligand by enzymatically hydrolyzing bacterial cells, and reacting the amino...
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