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Patent # Description
US-8,076,480 Process of preparing optically active allyl compound
Disclosed is a process of preparing an optically active allyl compound, e.g., as represented by formula (III): ##STR00001## comprising asymmetrically coupling...
US-8,076,479 Process and intermediates for the synthesis of ...
Disclosed is a process for the synthesis of compounds of Formula I ##STR00001## by sequentially aminating, first with a primary amine and then with a secondary...
US-8,076,478 Polyamine derivative and polyol derivative
A novel polyamine derivative, or polyol derivative, having a piperidylaminotriazine skeleton; salts of such compounds; a process for producing them; an organic...
US-8,076,477 Adsorbents for protein purification
Use of an affinity adsorbent for the separation, removal, isolation, purification, characterisation, identification or quantification of a proteinaceous...
US-8,076,476 Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits
Morpholino compounds are provided having the structure: ##STR00001## where R.sup.1 is selected from the group consisting of lower alkyl, di(lower...
US-8,076,475 Process
The present invention generally relates to a novel process for preparing vitronectin receptor antagonist compounds having a benzodiazepinyl core structure. This...
US-8,076,474 Methanesulfonate salts of abiraterone-3-esters and recovery of salts of abirater one-3-esters from solution in...
A salt of a compound of formula (I) may be made with methanesulfonic acid. The salt and salts with other acids may be prepared by recovering from methyl...
US-8,076,473 Process for starch modification
A starch thinning and etherification process is provided comprising the steps of (a) mixing a starch substrate with a thinning agent, an alkalizing agent and an...
US-8,076,472 RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering...
The present invention relates to compounds, compositions, and methods useful for modulating the expression of genes associated with respiratory and pulmonary...
US-8,076,471 RNAi expression constructs
The present invention provides compositions and methods suitable for expressing 1-x RNAi agents against a gene or genes in cells, tissues or organs of interest...
US-8,076,470 VMP-like sequences of pathogenic Borrelia species and strains
The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to...
US-8,076,469 TB diagnostic based on antigens from M. tuberculosis
The present invention is based on the identification and characterization of a number of novel M. tuberculosis derived proteins and protein fragments. The...
US-8,076,468 Nucleic acid molecules encoding Streptomyces 1AG3 serine proteases
Certain aspects of this disclosure relate to an isolated protease, and cleaning compositions containing the same. In some embodiments, the protease may comprise...
US-8,076,467 Nucleic acid inhibitors of glutamate receptors
The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the ...
US-8,076,466 Saccharidic fluorescent substrates, their process of preparation and their use
The present invention relates to fluorescent enzymatic substrates of saccharidic nature having a self-cleavable spacer arm functionalized by a fluorophore F and...
US-8,076,465 Method for manufacturing charge control agent
A method for manufacturing a charge control agent comprising steps of: an initiative chelating step by reacting with a monoazo compound represented by the...
US-8,076,464 Methods for carbon isotope labeling synthesis of ketones and amines by Suzuki coupling reactions using...
Methods and reagents for synthesizing carbon-isotope labeled ketones and amines by carbonylation via Suzuki coupling reaction using carbon-isotope labeled...
US-8,076,463 Polymer-von Willebrand factor-conjugates
The present invention relates to a proteinaceous construct (also designated as polymer-VWF-conjugate) comprising plasmatic and/or recombinant von Willebrand...
US-8,076,462 Method for producing antithrombin composition
The provision of an antithrombin composition having a desired .alpha.-form content rate or .beta.-form content rate is required. The invention provides a...
US-8,076,461 Methods and compositions for determining the purity of and purifying chemically synthesized nucleic acids
An antibody microarray is described comprising a plurality of antibodies immobilized on a substrate, wherein each antibody specifically binds to a synthetic...
US-8,076,460 Antibody and inhibitor, and transfection method or kit using them
The present invention provides a monoclonal antibody which specifically binds to human Toll-like receptor 3 and inhibits production of type 1 interferon. It...
US-8,076,459 Multispecfic deimmunized CD3-binders
The present invention provides a cytotoxically active CD3 specific binding construct comprising a first domain specifically binding to human CD3 and an...
US-8,076,458 Anti-claudin-4 antibody
An object of the present invention is to provide a monoclonal antibody which is useful as a diagnostic agent or a therapeutic agent for a disease relating to a...
US-8,076,457 Crystal of a cytochrome-ligand complex and methods of use
The teachings relates to the three-dimensional structure of a crystal of a cytochrome protein complexed with a ligand. The three-dimensional structure of four...
US-8,076,456 Fusion proteins comprising canine thymic stromal lymphopoietin protein and uses thereof
The present invention discloses a canine TSLP protein and a nucleic acid that encodes that protein. Peptide fragments of the protein that comprise specific...
US-8,076,455 Guanosine triphosphate (GTP)-binding protein-coupled receptor protein, BG37
The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel...
US-8,076,454 Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More...
US-8,076,453 Kinin B.sub.1 receptor peptide agonists and uses thereof
The present invention provides for novel kinin B1 receptors peptide agonists of formula (I) having very good to excellent affinities and selectivity for the...
US-8,076,452 Streptavidin-binding peptide
The invention relates to novel streptavidin binding peptides.
US-8,076,451 Selective delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally...
A polypeptide with a predominantly hydrophobic sequence long enough to span a membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more...
US-8,076,450 Treatment of ischemia
A system, including methods and compositions, for treatment of ischemia.
US-8,076,449 Therapeutic agents of colivelin for neurodegenerative diseases
The present invention relates to a pharmaceutical composition for the treatment and/or prevention of a neurodegenerative disease, comprising the following...
US-8,076,448 Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction
The invention provides methods of extracting a biodegradable polyester with a supercritical fluid effective to obtain a purified biodegradable polyester, such...
US-8,076,447 Poly (arylene sulfide) and production process thereof
A poly(arylene sulfide) having properties that a melt viscosity is 1 to 3,000 Pas as measured under conditions of a temperature of 310.degree. C. and a shear...
US-8,076,446 Optical layered body and method for producing optical layered body
An optical layered body having an excellent antistatic property and adhesion is provided. An optical layered body is provided that comprises an antistatic layer...
US-8,076,445 Oligocarbodiimides for the formation of crosslinked latex films
A composition comprising a carbodiimide and a polymer, wherein the carbodiimide comprises a reaction product of a) at least one of an aliphatic C.sub.4 to...
US-8,076,444 Curable compositions consisting of silanes with three hydrolysable groups
The invention relates to silane cross-linking curable compositions, comprising a polymer P with at least two terminal groups of the following formulae (I) and...
US-8,076,443 Preparation of polyhedral oligomeric silsesquioxane silanols and siloxides functionalized with olefinic groups
A synthetic process for polyhedral oligomeric silsesquioxanes (POSS) and polyhedral oligomeric silicates (POS) produces silanol and siloxide molecules...
US-8,076,442 Polyamino and/or polyammonium/polysiloxane copolymer compounds with polyalkylene oxide units in comb-shaped...
The invention concerns polyamino and/or polyammonium/polysiloxane copolymer compounds with polyalkylene oxide units in comb-shaped arrangement, a method for...
US-8,076,441 Process for bridging organically polymerizable silanes or silane resin systems containing hydroxy- or...
The present invention relates to a process for cross-linking a silane with the structure (IIa) ##STR00001## for the preparation of a product, comprising...
US-8,076,440 Polysiloxane block copolymers
The invention relates to polysiloxane block copolymers of the formula A[LB(S)Q].sub.m, where A is a polysiloxane block, L is a divalent organic linker, B is a...
US-8,076,439 Curable composition
The present invention has its object to provide a curable composition comprising a reactive silyl group-containing organic polymer component which allows slight...
US-8,076,438 Method for producing organopolysiloxanes
Organopolysiloxanes are prepared in a multistage process by a first partial hydrolysis with from 0.002 to 0.6 mol water per hydrolyzable chlorine and alcohol at...
US-8,076,437 Encapsulant material for optical component and light-emitting device
A light-emitting device is provided which uses an encapsulant material made from a polymer having a high relative light output. The light-emitting device...
US-8,076,436 Method for the production of superabsorbers
Superabsorbents are produced by polymerization in the presence of at least one unsaturated polyetherol selected from the group consisting of polyetherols having...
US-8,076,435 Acrylic copolymers with high heat-resistance and preparation thereof
An acrylic copolymer with high heat-resistance is provided. The acrylic copolymer includes repeat units of a monomer of Formula (1) and repeat units of a...
US-8,076,434 Amphoteric polymer and process for producing the same
The present invention has an object to provide an amphoteric polymer having high anti-soil redeposition ability and solubility with surfactants, and a process...
US-8,076,433 Vinyl alcohol-based polymer and film containing the same
Provided are a polyoxyalkylene modified vinyl alcohol-based polymer, including a polyoxyalkylene group in side chain, wherein the vinyl alcohol-based polymer...
US-8,076,432 Phosphonic compounds and methods of use thereof
Described herein are methods for producing phosphonic compounds and compounds thereof. Stable compositions of unsaturated phosphonic acid monomers are also...
US-8,076,431 High melt flow fluoropolymer
The present invention relates to a partially-crystalline copolymer comprising tetrafluoroethylene, hexafluoropropylene in an amount corresponding to...
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