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Patent # Description
US-8,101,735 Preparation of protective antigen
A polynucleotide sequence is provided comprising a nucleic acid sequence encoding recombinant Protective Antigen (rPA). Also provided are expression vectors and...
US-8,101,734 Ghrelin binding nucleic acids
The present invention is related to a nucleic acid, preferably binding to ghrelin, whereby the nucleic acid comprises a first stretch Box A, and a second...
US-8,101,733 Methods of evaluating mixtures of polysaccharides
Methods for analyzing mixtures of polysaccharides, for example heparin or a LMWH, using reduce end labeling are described. In general, the mixture of...
US-8,101,732 Methods of producing validamycin A analogs and uses thereof
This disclosure relates to validamycin A biosynthesis and in particular, to methods of producing validamycin A analogs and uses thereof. In a particular...
US-8,101,731 Yellow anionic disazo dyes
The present invention relates to novel yellow anionic dyes, a process for their preparation, certain novel intermediates necessary for their preparation and the...
US-8,101,730 Method for synthesizing rare-earth oxo isopropoxide
Provided is a method for synthesizing a rare-earth oxo isopropoxide safely with a high yield, using a rare-earth metal, which is more inexpensive than anhydrous...
US-8,101,729 Pegylated amino acid derivatives and the process to synthesize the same
The present invention is a series of novel pegylated amino acid derivatives containing branched polyethylene glycols, which are either the same or different...
US-8,101,728 TAB molecules
The present invention relates to TAB molecules, ADEPT constructs directed against TAG-72, and their use in therapy.
US-8,101,727 Compositions and methods of use for antibodies of c-Met
Antibodies and fragments that bind to the protein target c-Met, particularly to epitopes located in the c-Met extracellular domain, are provided, as are methods...
US-8,101,726 Ligands binding the complex of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) that inhibit...
Antibodies or other ligands specific for the binary uPA-uPAR complexes, for ternary complexes comprising uPA-uPAR and for complexes of uPAR and proteins other...
US-8,101,725 Monoclonal antibodies to basic fibroblast growth factor
The present invention is directed toward a neutralizing monoclonal antibody to basic fibroblast growth factor, a pharmaceutical composition comprising same, and...
US-8,101,724 High-affinity human antibodies to human protease-activated receptor-2
The present invention provides antibodies that bind to protease-activated receptor-2 (PAR-2) and methods of using same. According to certain embodiments of the...
US-8,101,723 Monoclonal antibodies to fibroblast growth factor receptor 2
The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods...
US-8,101,722 Less immunogenic binding molecules
The present invention provides a bispecific binding molecule, wherein said molecule comprises or consists of at least two domains whereby one of said at least...
US-8,101,721 Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof
The present invention is related to antibodies with binding affinity to fibroblast growth factor receptor 2 (FGFR2) optionally with binding affinity to other...
US-8,101,720 Immunoglobulin insertions, deletions and substitutions
An Fc variant of a parent Fc polypeptide, wherein said Fc variant exhibits altered binding to one or more Fc.gamma.Rs, wherein said Fc variant comprises at...
US-8,101,719 Humanized anti-CD47 antibody
The present invention relates to humanized antibodies binding to CD47; diabodies binding to human CD47, characterized in that a disulfide bond exists between...
US-8,101,718 Methods of administering porcine B-domainless fVIII
The present invention provides a method of administering porcine B-domainless factor VIII (OBI-1) to a patient having factor VIII deficiency to provide more...
US-8,101,717 Use of tropoelastin for repair or restoration of tissue
The present invention relates to tropoelastin and to tissue repair and restoration using elastic materials. Disclosed is a process for producing an elastic...
US-8,101,716 Human interferon-beta mutein
The present invention relates to a human interferon-beta mutein. In particular, the present invention relates to the human interferon-beta mutein having one or...
US-8,101,715 Ryanodine receptor polypeptides
The genes encoding ryanodine receptor homologs have been characterized from multiple insect families including lepidopteran tobacco budworm (Heliothis...
US-8,101,714 Teleost derived antimicrobial polypeptides
The invention is directed to an isolated polypeptide which (a) is obtainable from a teleost; (b) has antimicrobial activity; (c) binds to oligoguanosine and/or...
US-8,101,713 Prostate cancer diagnosis and treatment
The present invention relates to novel antibodies and their use for detecting, imaging, staging, treating and monitoring of prostate cancer, and/or metastasis...
US-8,101,712 Purification processes for echinocandin-type compounds
The present invention provides a method of preparing and purifying echinocandin-type compounds, such as pneumocandin Bo, WF 11899A, and echinocandin B. These...
US-8,101,711 Process to modify polymeric materials and resulting compositions
Disclosed is a method for modifying a polymer by carrying out a thermally-induced reaction in a mixing apparatus having a high shear environment and...
US-8,101,710 Membrane separation process for removing residuals from polyamine-epihalohydrin resins
This invention relates to a process for preparing polyamine-epihalohydrin resins having reduced levels of residuals. The process comprises (a) charging a...
US-8,101,709 Synthesis of conducting polymer nanofibers using an oligomer of a monomer as an initiator
The present invention involves synthesizing conducting polymer nanofibers by mixing an oxidant solution with a monomer solution, which includes a monomer and an...
US-8,101,708 Solvent resistant polymers
What is disclosed relates to polymers that resist dissolution in organic solvents, are vasodilators, and are tunable explosives. These polymers also form...
US-8,101,707 Process for the direct manufacture of polyglycerol polyricinoleate
A process for manufacturing polymers of glycerin and hydroxyl fatty acids, for example, polyglycerol polyricinoleates, which mix a polyglycerol with a hydroxyl...
US-8,101,706 Multifunctional forms of polyoxazoline copolymers and drug compositions comprising the same
The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically...
US-8,101,705 Polyester compositions containing cyclobutanediol having a certain combination of inherent viscosity and...
Described are articles, comprising polyester based composition, comprising dicarboxylic acid component as terephthalic acid residues and optionally, aromatic...
US-8,101,704 Continuous polymer-analogous reaction of reactive silane monomers with functionalized polymers
Functional polymers having silyl end groups are prepared in a continuous process by polymer analogous reaction of a reactive polymer and inter-reactive silane....
US-8,101,703 Precursor solution for polyimide/silica composite material, its manufacture method, and polyimide/silica...
A process for preparing a precursor solution for polyimide/silica composite material and a process for forming a polyimide/silica composite material film on a...
US-8,101,702 Silicone-containing composition
A silicone-containing composition comprises the reaction product of a first component and an excess of an isocyanate component relative to the first component...
US-8,101,701 Fumaric acid derivatives and ophthalmic lenses using the same
Fumaric acid derivatives and ophthalmic lenses using them are disclosed. More specifically, a fumaric acid derivative having a hydrophilic group and a...
US-8,101,700 Phosphonic polymers having a phosphinate backbone and methods of making and using thereof
Described herein are new phosphonic polymers and methods of making and using the same. The polymers are prepared by the polymerization of phosphonic acid...
US-8,101,699 Electron-transporting polymers
The invention relates to polymers useful in optoelectronic devices and comprising structural unit of formula I: ##STR00001## wherein R.sup.1 and R.sup.2 are...
US-8,101,698 Surface active prepolymers with both fluorine-containing groups and hydrophilic groups
Provided are surface modified contact lenses formed from one or more fumaric-or itaconic-containing prepolymers having polymerizable functionality that is...
US-8,101,697 Multi-functionalized high-trans elastomeric polymers
A method for preparing multi-functional high-trans elastomeric polymers that have various applications such as in vulcanizable rubber compositions, moisture...
US-8,101,696 Polyolefin solution polymerization process and polymer
A catalyst composition comprising a zirconium complex of a polyvalent aryloxyether and a polymerization processes employing the same, especially a continuous,...
US-8,101,695 Propylene based terpolymers
A propylene-based terpolymer comprising: a) from 10.0% by mol to 79.0% by mol of propylene derived units; b) from 89.5% by mol to 20.5% by mol of 1-butene...
US-8,101,693 Multi reactor process
This invention relates to the polymerization of ethylene polymers using a continuously stirred tank reactor (CSTR) that is connected in series to a tubular...
US-8,101,692 Slurry phase polymerisation process
A process comprising polymerising in a loop reactor of continuous tubular construction an olefin monomer optionally together with an olefin comonomer in the...
US-8,101,691 Systems and methods for fabricating polymers
Disclosed herein are various methods and systems for gas and liquid phase polymer production. In certain embodiments, the methods comprise manipulating...
US-8,101,690 Amine functional adducts and curable compositions comprising same
An amine functional adduct is obtained by admixing a stoichiometric excess of a cycloaliphatic diamine and a compound having an epoxide group and an alpha, beta...
US-8,101,689 Shape memory epoxy copolymer
The shape memory polymers disclosed are a reaction product of at least one reagent containing two active amino-hydrogen or two active phenolic-hydrogen with at...
US-8,101,688 Polylactic acid fiber yarn package, and textile products
Polylactic acid fibers excellent in wearing resistance and in the ability to smoothly pass through processing steps. The polylactic acid fibers contain a fatty...
US-8,101,687 Multimodal polyethylene material
The present invention relates to a polyethylene resin having a multimodal molecular weight distribution, said resin being further characterized in that it has a...
US-8,101,686 Interpolymer resin particles
Interpolymer resin particles comprised of 20% to 60% by weight of uncross-linked polyolefin e.g. polyethylene, polypropylene, and from 40% to 80% by weight...
US-8,101,685 Thermoplastic elastomer polyolefin in-reactor blends and molded articles therefrom
This invention relates to an in-reactor polymer blend comprising: (a) a first ethylene-containing polymer having a density of greater than 0.90 g/cm.sup.3 and a...
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