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Patent # Description
US-8,129,353 Methods of gene therapy using nucleic acid sequences for ATP-binding cassette transporter
The present invention provides nucleic acid and amino acid sequences of an ATP binding cassette transporter and mutated sequences thereof associated with...
US-8,129,352 Antisense antiviral compound and method for treating ssRNA viral infection
The invention provides antisense antiviral compounds and methods of their use and production in inhibition of growth of viruses of the Flaviviridae,...
US-8,129,351 Immunostimulatory nucleic acid molecules
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on their ability to stimulate an immune response and to redirect a Th2...
US-8,129,350 Method of lowering Glycaemic Index of foods
A method of delaying digestion by an animal or a human of carbohydrates in food, comprising administering an effective amount of one or more flavonoids to the...
US-8,129,349 Treatment of disease by inducing cell apoptosis
The present invention relates generally to the treatment and prevention of diseases characterized by excess cell proliferation and/or activation. In particular,...
US-8,129,348 Conjugates of biologically active proteins having a modified in vivo half-life
Disclosed are biologically active protein conjugates that comprise a biologically active polypeptide coupled via a peptide bond to a polypeptide comprising from...
US-8,129,347 Methods for treating autoimmune diseases using B7-H4 polypeptides and fragments thereof
The invention provides novel B7-H3 and B7-H4 polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing...
US-8,129,346 Compounds for enzyme inhibition
Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile...
US-8,129,345 MUC1-I.kappa.B kinase complexes and their activities
The disclosure provides methods of identifying and making compounds and pharmaceutical compositions containing the compounds that inhibit the interaction...
US-8,129,344 Method of reducing cell death by administering a Sfrp polypeptide
A purified paracrine factor of a mesenchymal stem cell, such as a Secreted frizzled related protein (Sfrp) is useful to reduce cell death an/or tissue injury...
US-8,129,343 Acylated GLP-1 compounds
Protracted GLP-1 compounds and therapeutic uses thereof.
US-8,129,342 High purity lipopeptides
The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying...
US-8,129,341 Methods for treating diabetic wounds
The present invention relates to a method of treating chronic wounds using calreticulin. In particular, the invention relates to the treatment of chronic...
US-8,129,340 Inhibitors of protein phosphatase 1, GADD34 and protein phosphatase 1/GADD34 complex, preparation and uses thereof
The present invention relates to the use of a protein phosphatase inhibitor selected from an inhibitor of the catalytic subunit of the protein phosphatase 1...
US-8,129,339 Microencapsulation and sustained release of biologically active polypeptides
The invention relates to compositions and methods for the sustained release of biologically active polypeptides. The sustained release compositions of this...
US-8,129,338 Nitric oxide-blocked cross-linked tetrameric hemoglobin
The present invention includes compositions containing carboxamidomethylated cross-linked hemoglobin where the cysteine moiety of the hemoglobin includes a...
US-8,129,337 Compositions comprising epigallocatechin gallate and protein hydrolysate
The present invention describes a composition comprising EGCG and a protein hydrolysate.
US-8,129,336 Inhibitor of the uracil-DNA glycosylase enzyme and uses thereof
The present invention relates to a protein which has the capacity to bind to and inhibit the viral uracil DNA glycosylase (UDG) enzyme and its use as a...
US-8,129,335 Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome...
Disclosed here is a method for measuring the kinetics (i.e., the molecular flux rates--synthesis and breakdown or removal rates) of a plurality of proteins or...
US-8,129,334 Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal...
The disclosure relates generally to neurodegenerative disorders and more specifically to a group of presenilin/G-protein/c-src binding polypeptides and methods...
US-8,129,333 Antigen delivery vectors and constructs
The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon...
US-8,129,332 Reagents and methods for smooth muscle therapies
The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as...
US-8,129,331 Specific binding agents of human angiopoietin-2
Disclosed are peptides that bind to Ang-2. Also disclosed are peptibodies comprising the peptides, methods of making such peptides and peptibodies, and methods...
US-8,129,330 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
Methods are provided for the preparation of conjugates of a variety of bioactive components, especially proteins, with water-soluble polymers (e.g.,...
US-8,129,329 Natural polypeptides for oral health care
The present invention relates generally to dental diseases, caries and periodontal disease. More specifically, the invention relates to Lactoferrin and...
US-8,129,328 Compositions comprising sulfonated estolides and alkyl ester sulfonates, methods of making them, and...
Compositions comprising sulfo-estolides and alkyl ester sulfonates are described. Detergent formulations, such as laundry detergents, softeners, and other...
US-8,129,327 Packaging for high moisture bar soap
Packaging is provided for high moisture bar soap compositions to address a number of potential problems associated with high moisture bar soap compositions,...
US-8,129,326 Alkoxylated polyalkanolamines
The present invention relates to polymers obtainable by condensation of N-(hydroxy-alkyl)amines and reacting the remaining hydroxy and/or secondary amino groups...
US-8,129,325 Stabilized propyl bromide compositions
Certain substituted phenolic compounds when used with or without 1,2-epoxides as the sole stabilizer components are very effective in stabilizing n-propyl...
US-8,129,324 Surfactant compounds
Fatty esters of oligoesters of a dicarboxylic acid and a polyol retaining at least one free hydroxyl group, particularly of the formula (I): ...
US-8,129,323 Solid laundry detergent composition comprising alkyl benzene sulphonate, carbonate salt and carboxylate polymer
A solid laundry detergent composition in particulate form comprising a plurality of particulate components, the composition comprises: alkyl benzene sulphonate...
US-8,129,322 Photosensitive-resin remover composition and method of fabricating semiconductor device using the same
A photosensitive-resin remover composition includes an amine compound and de-ionized water, an amount of the de-ionized water being about 45% to about 99% by...
US-8,129,321 Liquid compostion for cleaning a nozzle surface, method of cleaning a nozzle surface using the liquid...
Provided are a liquid composition for cleaning a nozzle surface of an inkjet printer, a method of cleaning a nozzle surface using the liquid composition and an...
US-8,129,320 Lubricant oil compositions to optimize internal combustion engine performance
The present disclosure relates to lubricant oil compositions formed from base stock oils to optimize internal combustion engine performance. Base stock oils are...
US-8,129,319 Lubricating composition
A lubricating composition comprising a base oil, (A) one or more kinds of compounds selected from phenolic antioxidants and aminic antioxidants, and (B) an...
US-8,129,318 Methods and compositions for determination of fracture geometry in subterranean formations
Disclosed herein is a method comprising disposing in a formation fracture, a proppant and/or a fracturing fluid that comprises a radiation susceptible material...
US-8,129,317 Viscosified treatment fluids comprising polycarboxylic acid gelling agents and associated methods
In one embodiment, the present invention provides a fluid comprising: an aqueous base fluid; and a gelling agent that comprises a polymerizable polycarboxylic...
US-8,129,316 Method of creating a carbon dioxide hydrate
A method of creating a carbon dioxide hydrate is disclosed. The preferred steps include supplying liquid carbon dioxide and a dissociation agent to a...
US-8,129,315 Labelling strategies for the sensitive detection of analytes
The present invention relates to methods and reagents for detecting analytes, e.g. nucleic acids. The new methods and reagents allow a simple and sensitive...
US-8,129,314 Plant protection composition absorbates and products for plant protection
Absorbates having a high loading of particular substances for use in plant protection compositions, the use of a special process for the preparation of the...
US-8,129,313 Aqueous agrochemical concentrate composition
An aqueous agrochemical composition and in particular an agrochemical concentrate comprises (a) a non-encapsulated aqueous solution or dispersion of an...
US-8,129,312 Use of defined alcohol alkoxylates as adjuvants in the agrotechnical field
The present invention relates to the use of specific amphiphilic alkoxyates as synergistic adjuvant for agrotechnical applications. Suitable agrotechnical...
US-8,129,311 Heat-sensitive transfer image-receiving sheet
A heat-sensitive transfer image-receiving sheet, containing a support and an interlayer, an insulation layer and a receptor layer formed on the support in that...
US-8,129,310 Heat-sensitive transfer sheet
A heat-sensitive transfer sheet containing a base film, a dye layer formed over one surface of the base film and containing a heat-transferable dye and a resin,...
US-8,129,309 Heat-sensitive transfer sheet for use in heat-sensitive transfer system and image-forming method using...
A heat-sensitive transfer sheet, comprising a base film, at least three heat-sensitive transfer layers containing heat-sensitively transferable dyes and a...
US-8,129,308 Thermal transfer image-receiving sheet and surface condition improver
A thermal transfer image-receiving sheet comprising a heat-insulating layer and an image-receiving layer on a support, wherein the receiving layer contains...
US-8,129,307 Thermosensitive recording medium
The present invention provides a thermosensitive recording medium, which is excellent in stamping ability, anti-scratching ability, and water and plasticizer...
US-8,129,306 Non-platinum bimetallic polymer electrolyte fuel cell catalysts
A polymetallic nanoparticle alloy having enhanced catalytic properties including at least one noble metal and at least one base metal, where the noble metal is...
US-8,129,305 Catalyst and method for converting natural gas to higher carbon compounds
A catalyst composition and process facilitates the oxidative reforming of low molecular weight hydrocarbons, such as methane, to other hydrocarbons having 2 or...
US-8,129,304 Intermetallic compound Ni.sub.3Al catalyst for reforming methanol and methanol reforming method using same
A methanol-reforming catalyst containing a Ni.sub.3Al intermetallic compound as a main component that is superior in heat resistance and abrasion resistance and...
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