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Patent # Description
US-8,129,152 Method of producing enantioselective immobilized candida rugosa lipase
Immobilization of Candida rugosa lipase on a carrier selected from the group consisting of macroporous adsorbent resin of the acrylic type, synthetic epoxy...
US-8,129,151 L-glutamic acid-producing bacterium and method for producing L-glutamic acid
L-Glutamic acid is produced by culturing in a liquid culture medium a microorganism belonging to the genus Pantoea or Serratia and having an ability to produce...
US-8,129,150 Mixture of reversibly inhibited enzymes
The invention relates to composition or a kit containing an enzyme that is reversibly inhibited by means of a chemical modification and an enzyme which is...
US-8,129,149 Rapid and sensitive method to measure endonuclease activity
A rapid and sensitive method to measure endonuclease activity comprising reacting a substrate suspected of having endonuclease activity with a synthetic...
US-8,129,148 Process for preparation of chondroitin fraction
Provided are a method for producing a fraction containing more than 50% of CH represented by the general formula (1), which comprises at least the step of...
US-8,129,147 Meningococcal oligosaccharide linked polysaccharides and diptheria protein conjugate vaccine for all ages
Methods for producing quadrivalent meningococcal meningitis polysaccharide and conjugate vaccines for serotypes A, C, Y and W-135 disclosed. Neisseria...
US-8,129,146 Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
Novel insulin precursors and insulin precursor analogs comprising a connecting peptide (mini C-peptide) of preferably up to 15 amino acid residues and...
US-8,129,145 Production of glycoproteins
An improved system for large scale production of glycoproteins in cell culture is provided. In accordance with the present invention, cells expressing a...
US-8,129,144 Papilloma pseudovirus and preparation
The invention involves a papilloma pseudovirus that can induce immune response after oral intake as well as its preparation. It is characterized in that HPV or...
US-8,129,143 Method for production of a compound in a eukaryotic cell
The present invention relates to a eukaryotic cell containing peroxisomes that are capable to fuse with a membrane-structure of the cell involved in the...
US-8,129,142 Mutations in ion channels
A method of identifying a subject predisposed to a disorder associated with ion channel dysfunction, comprising ascertaining whether at least one of the genes...
US-8,129,141 Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an ...
US-8,129,140 Thermophilic endo-glucanase and uses thereof
A novel thermophilic endo-glucanase, nucleic acid encoding the endo-glucase, and uses thereof in converting ligocellulosic material to fermentable sugars.
US-8,129,139 Process for obtaining botulinum neurotoxin
Rapid, animal protein free, chromatographic processes and systems for obtaining high potency, high yield botulinum neurotoxin for research, therapeutic and...
US-8,129,138 Method and apparatus for determining an analyte in a liquid sample
A method for the determination of an analyte in a liquid sample, especially a body liquid sample, with the aid of an analytical apparatus. The apparatus...
US-8,129,137 Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and...
A two-photon probe for real-time monitoring of intracellular free zinc ions is provided. The two-photon probe is represented by Formula 1: ##STR00001## wherein...
US-8,129,136 Kit for performing an assay
The present invention relates to a kit for performing an assay. The kit comprises luminol, an oxidant, an electron mediator and a hypernucleophilic acylation...
US-8,129,135 Method for diagnosing cardiovascular diseases
Method for diagnosing a cardiovascular disease in an individual comprising the steps of: providing a sample of an individual; determining the amount of...
US-8,129,134 Methods of cleaving DNA with rationally-designed meganucleases
Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases...
US-8,129,133 Devices and methods for the rapid, reliable detection and determination of acrylamide concentration in food...
A device and associated analytical method to use for the sensitive detection and accurate, rapid determination of acrylamide in food substances is presented....
US-8,129,132 Detection of autoantibodies reactive with pancreatic islet cell antigenic molecules and/or insulin
A method of screening a sample of body fluid obtained from an animal subject for analyte autoantibodies reactive with one or more antigenic molecules selected...
US-8,129,131 Pin1 as a marker for abnormal cell growth
Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an...
US-8,129,130 High affinity antibodies against HMGB1 and methods of use thereof
Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a vertebrate cell, and for inhibiting an inflammatory...
US-8,129,129 Method for diagnosing tumors
The present invention describes a method for diagnosing tumors of the reproductive organs which is characterized by determination of the afamin content in a...
US-8,129,128 Immunoassay reagent compositions for diagnosing multiple sclerosis
This application is related to immunoassay reagent compositions comprising a glycan reagent for diagnosing multiple sclerosis.
US-8,129,127 Assay for immunosuppressant drugs
The invention provides immunoassays for immunosuppressant drugs, wherein the assay is carried out under high salt conditions to achieve improved sensitivity....
US-8,129,126 Use of the 4-1BB receptor for identifying and/or separating activated regulatory Th cells (Treg)
The invention relates to the use of the 4-1BB receptor for identifying and/or separating specific regulatory Th cells after activation with an antigen,...
US-8,129,125 Gene and protein expression profiles associated with the therapeutic efficacy of EGFR-TK inhibitors
The present invention provides protein and gene expression profiles indicative of whether a patient afflicted with non-small cell lung cancer is likely to be...
US-8,129,124 Agents and methods related to reducing resistance to apoptosis-inducing death receptor agonists
Provided herein is a method of reversing or preventing a target cell's resistance to a death receptor agonist. Also provided are methods of screening for...
US-8,129,123 Methods for assessing atherogenesis by determining oxidized phospholipid to apolipoprotein B ratios
The present invention relates to the analysis of oxidized phospholipids (OxPL) on apolipoprotein B-100 in patients at high risk or with documented coronary...
US-8,129,122 Method of predicting metastasis of oral cavity cancer into cervical lymph node and diagnosis kit to be used in...
A method for objectively predicting possibility of metastasis to a cervical lymph node in an early stage for an individual case diagnosed as an oral cavity...
US-8,129,121 Regulation of lipid droplet formation by modulation of FIT1 and FIT2 and uses thereof
This invention provides methods of regulating fat storage in tissue by modulating the levels of Fibrate Induced Transcript 1 (FIT1) and/or Fibrate Induced...
US-8,129,120 Methods for genetic analysis of DNA to detect sequence variances
Methods for determining genotypes and haplotypes of genes are described. Also described are single nucleotide polymorphisms and haplotypes in the ApoE gene and...
US-8,129,119 System for manipulating nucleic acids
The present invention provides an improved system for linking nucleic acids to one another. In particular, the present invention provides techniques for...
US-8,129,118 Magnetic glass particles, method for their preparation and uses thereof
This invention relates to magnetic particles having a glass surface which are substantially spherical. This invention also relates to methods for making them,...
US-8,129,117 Genetic markers for assessing risk of developing bipolar disorder
This document provides methods and materials related to genetic markers of Bipolar Disorder (BD) and Schizophrenia (SZ). For example, methods for using such...
US-8,129,116 Methods for nucleic acid manipulation
A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination...
US-8,129,115 Method of modifying nucleotide chain
A nucleotide chain to be modified, a nucleotide having a particular base that is different from bases constituting the nucleotide chain, an enzyme catalyzing...
US-8,129,114 Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
EGFR biomarkers useful in a method for predicting the likelihood that a mammal that will respond therapeutically to a method of treating cancer comprising...
US-8,129,113 Analysis chip with reference range, kits and methods of analysis
Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a...
US-8,129,112 Polymorphisms in the human CYP2D6 gene promoter region and their use in diagnostic and therapeutic applications
Provided are polynucleotides of molecular variant promoters of the CYP2D6 gene which, for example, are associated with abnormal drug response or individual...
US-8,129,111 Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods...
The presently described subject matter is directed to water-soluble conjugated polyene compounds that exhibit aggregation induced emission, as well as to water...
US-8,129,110 Probe, probe set, probe-immobilized carrier, and genetic testing method
A nucleic acid probe for classification of pathogenic bacterial species is capable of collectively detecting bacterial strains of the same species and...
US-8,129,109 Probe, probe set, probe-immobilized carrier, and genetic testing method
A nucleic acid probe for classification of pathogenic bacterial species is capable of collectively detecting bacterial strains of the same species and...
US-8,129,108 Probe, probe set, probe-immobilized carrier, and genetic testing method
A nucleic acid probe for classification of pathogenic bacterial species is capable of collectively detecting bacterial strains of the same species and...
US-8,129,107 Bisulfite conversion of DNA
The present invention relates to an improved method for the bisulfite conversion of DNA. In certain time-temperature ranges the efficacy of the bisulfite...
US-8,129,106 Sequence-specific detection of methylation in biomolecules
A method for detecting sequence specific methylation in a biomolecule, comprising: (a) contacting the biomolecule with an S-adenosyl-L-methionine-dependent...
US-8,129,105 Method and apparatus for the non-invasive measurement of tissue function and metabolism by determination of...
A non-invasive measurement of biological tissue reveals information about the function of that tissue. Polarized light is directed onto the tissue, stimulating...
US-8,129,104 Platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and anticoagulant...
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the...
US-8,129,103 Use of a platelet preservation composition comprising a short to ultra-short acting antiplatelet agent and...
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the...
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