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Patent # Description
US-9,314,544 Durable hydrophilic coating compositions
A durable hydrophilic coating composition is provided comprising a film forming polymer, a wetting agent and from about 0.001% to about 40%, by weight of the...
US-9,314,543 Vent stick air freshener with dual action bodies and air flow tunnel
A vent stick air freshener has a pair of vent rods extending rearwardly from an annular head with a hollow therein, an open front end and an open rear end...
US-9,314,542 Method for sterilizing surgical batteries
The invention is an apparatus for sterilizing surgical batteries.
US-9,314,541 In vivo imaging method for cancer
The present invention provides a method useful in the diagnosis and monitoring of cancer wherein there is an abnormal expression of PBR. The method of the...
US-9,314,540 Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system
This invention relates to novel compounds suitable as precursors for the preparation of certain .sup.18F labelled positron emission tomography (PET) tracers....
US-9,314,539 Nanosphere-histone acetyltransferase (HAT) activator composition, process and methods thereof
The present invention is in relation to a composition including nanosphere and histone acetyltransferase (HAT) activator. The nanosphere is carbon nanosphere...
US-9,314,538 Nucleic acid molecules encoding antibody drug conjugates (ADC) that bind to 191P4D12 proteins
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal...
US-9,314,537 SPARC binding ScFcs
The invention provides compositions comprising SPARC binding ScFc and its use.
US-9,314,536 Compounds and methods for the treatment of EGFR positive diseases
Disclosed herein are anti-EGFR antibodies conjugated with maytansinoid drugs for targeted delivery to disease tissues. Methods related to the preparation and...
US-9,314,535 Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
The present invention is directed to an inventive polymeric carrier molecule according to generic formula (I) and variations thereof, which allows for efficient...
US-9,314,534 Polymer conjugates of interferon beta-1A and uses
An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and the...
US-9,314,533 Conformations of divergent peptides with mineral binding affinity
A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1,...
US-9,314,532 Drug delivery vehicle
The present disclosure provides targeted drug delivery vehicle compositions comprising a drug composition and targeted poly-amino-acid subunits, methods of...
US-9,314,531 Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof
The present invention provides a wound healing composition comprising a biocompatible hydrogel membrane wherein the hydrogel membrane has one or more of the...
US-9,314,530 Composition, in aqueous medium, that comprises at least a hyaluronic acid and at least an hydrosoluble salt of...
A composition including at least one crosslinked or non-crosslinked hyaluronic acid, or one of its salts, and at least one water-soluble salt of sucrose...
US-9,314,529 Nucleic acid delivery composition and carrier composition, pharmaceutical composition using the same, and...
An excellent nucleic acid delivery composition is provided which has reduced cytotoxicity and improved nucleic acid introduction efficiency and gene expression...
US-9,314,528 Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
Provided herein are low salt ophthalmic pharmaceutical composition and methods of use thereof, for example, in the treatment of dry eye syndrome.
US-9,314,527 Transdermal delivery patch
A composition suitable for use in a transdermal delivery patch for administration of a biologically active compound, the composition comprising a phosphate...
US-9,314,526 Highly penetrating compositions with benzocaine for treating disordered tissues
Compositions and methods for treating disordered tissues, such as caused by pathogens and/or by toxins. The treatment compositions include an anti-infective...
US-9,314,525 Picropodophyllin polymorph C and its use in cancer therapy
The invention relates to novel polymorphs of picropodophyllin, methods for preparing said polymorphs and pharmaceutical compositions comprising said polymorphs,...
US-9,314,524 Topical formulations of Flucytosine
The invention relates to topical formulations of flucytosine which demonstrate a clear advantage over currently available therapeutic regimens for the treatment...
US-9,314,523 Ingestible salt grabber
Disclosed herein include embodiments related to compositions, devices, computer systems, computer-implemented methods, and computer program products associated...
US-9,314,522 Antitumors combinations containing antibodies recognizing specifically CD38 and bortezomib
Pharmaceutical composition comprising an antibody specifically recognizing CD38 and bortezomib.
US-9,314,521 Adjuvant compound
The invention is directed to a compound according to the formula [1] wherein R.sup.1 and R.sup.2 are branched or straight groups having up to 17 atoms selected...
US-9,314,520 Adjuvant composition containing poly-gamma-glutamic acid-chitosan nanoparticles
The present invention relates to an adjuvant composition containing poly-gamma-glutamic acid-chitosan nanoparticles and a vaccine composition containing the...
US-9,314,519 Liquid stable virus vaccines
The present invention discloses liquid stable vaccines that comprise a live attenuated virus, 10-30% sugar additive, and an amino acid. The present invention...
US-9,314,518 Treatment of streptococcal infections
Methods of treating a Streptococcus pneumoniae infection are described herein.
US-9,314,517 Parasite vaccine
Compositions and methods for the development and use of a vaccine that includes one or more FusM antigens in a carrier adapted to trigger a FusM-specific immune...
US-9,314,516 Conditional superagonist CTL ligands for the promotion of tumor-specific CTL responses
What is described is a novel genetic screen, involving recombinant technology and class I antigen cross-presentation, to search for supraoptimal superagonists...
US-9,314,515 Targeted treatment for patients with estrogen receptor negative and progesterone receptor negative breast cancers
Treatments for estrogen receptor and progesterone receptor negative breast cancer or estrogen receptor, progesterone receptor and c-erbB2 negative (triple...
US-9,314,514 Modified neurotoxins with poly-glycine and uses thereof
The present invention is concerned with modified neurotoxins. Specifically, it relates to a modified biologically active neurotoxin polypeptide comprising at...
US-9,314,513 Treatment of mammalian physiological reaction of IgE antibodies present in said mammal upon contact with the...
A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with...
US-9,314,512 Treatment of synucleinopathies
This invention relates generally to treating synucleinopathies in subjects that are not clinically diagnosed with a lysosomal storage disease, as well as...
US-9,314,511 Method for treatment of cardiac disorders
The present invention is directed to systems and methods for delivering therapy for a cardiac disorder, wherein the system comprises a source for supplying a...
US-9,314,510 Human laminin .alpha.2 chain LG3 domain and active peptides promoting cell adhesion, spreading, migration, and...
The present invention relates to human laminin .alpha.2 chain LG3 domain and active peptides promoting cell adhesion, spreading, migration, and neurite...
US-9,314,509 Pharmaceutical compositions of melanocortin receptor ligands
The present invention relates to improvements in compositions containing peptides that are ligands of one or more of the melanocortin receptors (MC-R), or...
US-9,314,508 Use of somatostatin analogs in control of hypoglycemia
The present invention relates to the use of a Somatostatin (SRIF) analog which has a high binding affinity to human SSTR1,2,3,5, or a pharmaceutically...
US-9,314,507 Methods of treatment of heart failure with natriuretic peptides
Methods of treating heart failure, or decreasing blood pressure, comprising administering an NP at an appropriate dose, or in an amount sufficient to provide...
US-9,314,506 Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors
Methods and compositions are provided for stimulating insulin production, increasing beta cell mass, or decreasing beta cell loss in a subject. For example,...
US-9,314,505 Combination treatments and compositions for wound healing comprising viral VEGF
Viral VEGF and viral anti-inflammatory cytokine compositions, methods of treatment using them, and kits containing them for use in the promotion and/or...
US-9,314,504 Use of members of IL-10 cytokine family
The invention relates to a novel use of the members of the IL-10 cytokine family in wound healing. Particularly, the invention relates to the use of the member...
US-9,314,503 Sustained release systems and preparation method thereof
The present invention relates to a hydrophilic drug and .beta.-tricalcium phosphate (.beta.-TCP) coating on a surface area of biopolymer matrix to form a...
US-9,314,502 Treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain
The present invention relates to the use of Meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain. In a preferred embodiment...
US-9,314,501 Method of regulating neuronal axon elongation
The present invention includes a treating step of treating neuronal growth cone with a regulatory factor to regulate macropinocytosis caused by a repulsive axon...
US-9,314,500 Non-N-glycosylated recombinant human annexin A2
Methods for the expression and purification of non-N-glycosylated human Annexin A2 in yeast, e.g., in Pichia pastoris, purified Annexin A2 produced by those...
US-9,314,499 Annexin A2 and tissue plasminogen activator for treating vascular disease
The use of tPA to treat hemorrhagic transformation, neurotoxicity has been limited to short treatment time windows because a high dose of tPA required to...
US-9,314,498 Bacteriocin derived from Lactobacillus rhamnosus
Provided is a bacteriocin that is capable of being easily mass-produced, has high antimicrobial activity even at low concentration, has a wide antimicrobial...
US-9,314,497 E2F as a target of hormone refractory prostate cancer
The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of...
US-9,314,496 Insoluble dietary fiber-containing product derived from grain seeds
This invention provides a product safe for treating, improving or preventing an inflammatory bowel disease such as ulcerative colitis, and provides a product...
US-9,314,495 Process for pygeum extraction
An improved process for the extraction of pygeum from the plant of the family rosacaea, amygdales tribe, genus Prunus species domestica (Indian Prunus) and...
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