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Patent # Description
US-9,315,598 Low stress flowable dental compositions
A photopolymerizable and photocleavable (P&P) resin monomer is derived from a reactive photoresponsible moiety via various linkages to form photopolymerizable...
US-9,315,597 Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass...
The disclosure relates to compositions containing 1,1-disubstituted alkene compounds capable of preparing polymers having glass transition temperatures above...
US-9,315,596 Method for production of vinyl chloride-based polymer by suspension polymerization
The present invention provides a method of preparing vinyl chloride polymer having excellent processability and high bulk density by the separate stepwise...
US-9,315,595 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation
Disclosed is a method of preparing terminally functionalized telechelic polymers using a cationic living polymer product or a terminal tert-chloride chain end...
US-9,315,594 Titanium-catalyst system comprising substituted cyclopentadienyl, guanidine and diene ligands
The invention relates to a catalyst system for the polymerization of olefins comprising a metal complex of formula CyLMD and an activating cocatalyst, wherein M...
US-9,315,593 Catalyst systems comprising pyridyldiamido transition metal complexes and chain transfer agent and use thereof
Pyridyldiamido transition metal complexes are disclosed for use in alkene polymerization with chain transfer agent.
US-9,315,592 Process for producing procatalyst composition with alkoxyalkyl ester internal electron donor and product
Disclosed herein are processes for preparing procatalyst compositions with an internal electron donor containing greater than 4.5 wt % of a compounded...
US-9,315,591 Modified phosphinimine catalysts for olefin polymerization
Olefin polymerization is carried out with a supported phosphinimine catalyst which has been treated with a long chain substituted amine compound.
US-9,315,590 Catalytic system for conjugated diene polymerisation, polymerisation method and functional polymer obtained
The present invention relates to a novel catalytic system for polymerization, and more particularly for preparing conjugated diene polymers bearing a polar...
US-9,315,589 Processes for the removal of rubber from non-hevea plants
Provided herein are organic solvent-based processes for the removal of rubber from non-Hevea plants such as guayule shrubs. By the use of the processes, solid...
US-9,315,588 Compositions and methods for recombinant synthesis of high molecular weight hyaluronic acid
Provided is a novel hyaluronan synthase (HAS2), isolated nucleic acids encoding it, and expression vectors which express the novel HAS2. Also provided are cell...
US-9,315,587 Oligosaccharide compounds
The invention relates generally to oligosaccharide compounds and the use of these compounds as pharmaceuticals for treating diseases or conditions in which it...
US-9,315,586 Method and carrier complexes for delivering molecules to cells
The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic...
US-9,315,585 Anti-GD2 antibodies
In this application are described chimeric, humanized, affinity matured, stability enhanced, and bispecific Anti-GD2 antibodies and fragments thereof. Also...
US-9,315,584 LH-type bispecific antibody
Provided are a novel diabody type bispecific antibody, the function of which as a bispecific antibody is improved to provide a higher additional value, such as...
US-9,315,583 Assays for detecting antibodies specific to therapeutic anti-IgE antibodies and their use in anaphylaxis
The invention provides methods and reagents useful for detecting anti-drug antibodies of IgE isotype to therapeutic anti-IgE antibodies, and methods for...
US-9,315,582 Anti-endoglin antibodies and knockin mice expressing novel human/mouse chimeric endoglin
Provided are compositions and methods that relate to prophylaxis and therapy of angiogenesis associated disease and includes novel knockin mice which express...
US-9,315,581 Immuno-conjugates and methods for producing them
The present invention provides an isolated protein comprising an immunoglobulin variable region comprising at least two cysteine residues positioned within...
US-9,315,580 Vaccines directed to langerhans cells
The present invention includes isolated anti-Langerin vaccines, methods for making and using an isolated anti-Langerin antibody or binding fragment thereof and...
US-9,315,579 Antigen binding proteins that bind CCR2
There is disclosed compositions and methods relating to or derived from anti-CCR2 antibodies. More specifically, there is disclosed fully human antibodies that...
US-9,315,578 High functional bispecific antibody
[Problem] The purpose of the present invention is to provide a bispecific antibody that is structurally stable, and can show alone a sufficient effect without...
US-9,315,577 Anti-hepcidin antibodies and methods of use
The invention relates to monoclonal antibodies that bind hepcidin and methods of making and using such antibodies. Also provided are methods of treating...
US-9,315,576 Antigen binding polypeptides
The invention relates to a platform technology for production of antigen binding polypeptides having specificity for a desired target antigen which is based on...
US-9,315,575 Methods of treatment using human antibody molecules for IL-13
Specific binding members, in particular human anti-IL-13 antibody molecules and especially those which neutralise IL-13 activity. Methods for using anti-IL-13...
US-9,315,574 Low acidic species compositions and methods for producing and using the same
The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods,...
US-9,315,573 Anti-TNF-alpha antibodies and their uses
The present disclosure relates to antibodies directed to the tumor necrosis factor alpha ("TNF-.alpha.") and uses of such antibodies, for example, to treat...
US-9,315,572 Stable and soluble antibodies inhibiting TNF alpha
The present invention relates to particularly stable and soluble scFv antibodies and Fab fragments specific for TNF.alpha., which comprise specific light chain...
US-9,315,571 Specific binding members for NGF
Specific binding members for Nerve Growth Factor (NGF), in particular anti-NGF antibody molecules, especially human antibody molecules, and especially those...
US-9,315,570 Composition comprising a mixture of CD95-Fc isoforms and methods of producing same
The present invention relates to a composition comprising a mixture of fusion protein isoforms, each fusion protein comprising an extracellular CD95 domain or a...
US-9,315,569 Antibodies and vaccines for use in therapeutic and diagnostic methods for .alpha.-synuclein-related disorders
Methods of treating or delaying onset of a neurodegenerative disorder with .alpha.-synuclein pathology in an individual comprise administering an antibody which...
US-9,315,568 Cadherin-11 EC1 domain antagonists for treating inflammatory joint disorders
The present invention relates to Cadherin-11 antagonists and compositions comprising Cadherin-11 antagonists. The invention also relates to methods for treating...
US-9,315,567 T-cell redirecting bispecific antibodies for treatment of disease
The present invention concerns compositions and methods of use of T-cell redirecting complexes, with at least one binding site for a T-cell antigen and at least...
US-9,315,566 Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for...
US-9,315,565 Method for producing protein
The present invention relates to a recombinant host cell, wherein the cell is modified to increase the expression levels of Ero1 and XBP1 relative to the...
US-9,315,564 Cosmetic or pharmaceutical compositions comprising metalloproteinase inhibitors
Peptides of general formula (I): R.sub.1AA.sub.1-AA.sub.2-AA.sub.3-AA.sub.4-R.sub.2 stereoisomers thereof, mixtures thereof or the cosmetically or...
US-9,315,563 Peptides that inhibit angiotensin converting enzyme and peptides with antioxidant activity purified from...
Described herein are methods of identifying and releasing bioactive peptides from ovotransferrin The method involves (a) contacting ovotransferrin with a...
US-9,315,562 High-strength collagen fiber membrane and a manufacturing method thereof
The object of the present invention is to provide a collagen fiber membrane, which has sufficient strength and can be used as a cell culture substrate, a...
US-9,315,561 Compositions comprising the NC2 domain of collagen IX and methods of using same
The present invention relates to the newly identified timerization initiating and stagger determining capacity of the NC2 domain of collagen IX. The invention...
US-9,315,560 Purification of VWF for increased removal of non-lipid enveloped viruses
The present invention provides methods for purifying Von Willebrand factor (VWF) for increased removal of non-lipid enveloped viruses.
US-9,315,559 Methods and compositions for generating an immune response by inducing CD40 and pattern recognition receptor...
Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible pattern recognition receptor adapter,...
US-9,315,558 Use of interleukin 10 mRNA transfected macrophages in anti-inflammatory therapies
The present invention relates to the field of cell-based therapeutics. Specifically, the invention is concerned with a composition comprising a macrophage...
US-9,315,557 IL-17A binding molecules and medical uses thereof
The present invention relates to a polypeptide inhibiting the activity of glycosylated IL-17A, wherein the polypeptide comprises or consists of an amino acid...
US-9,315,556 Compositions and methods
The present invention is directed to a polypeptide which comprises: (i) an Rv1753c protein sequence; (ii) a variant of an Rv1753c protein sequence; or (iii) an...
US-9,315,555 Clostridium difficile antigens
The present invention relates to recombinant Clostridium difficile antigens based on a polypeptide, consisting of or comprising an amino acid sequence having at...
US-9,315,554 Compositions and methods related to protein A (SpA) variants
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium....
US-9,315,553 Expression of chimeric KSAC protein and method of producing soluble proteins by high pressure
The present invention encompasses vaccines or compositions comprising the chimeric KSAC protein that possesses immunogenic and protective properties, and...
US-9,315,552 Recombinant cytotoxin as well as a method of producing it
The subject of the present invention is a method of modifying proteinaceous toxins through the addition of an NLS motif. The resulting cytotoxin facilitates the...
US-9,315,551 Porcine circovirus type 2 vaccines
The present invention is based on the ORF3 gene of Porcine Circovirus Type 2 (PCV2) and the identification of tis apoptotic role. This discovery has led to the...
US-9,315,550 Beta sheet tapes ribbons in tissue engineering
There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel...
US-9,315,549 Treatment methods using atoxic neurotoxin derivatives
The present invention relates to a treatment method. This method involves contacting a subject with an isolated, physiologically active, atoxic derivative of a...
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