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Patent # Description
US-9,345,705 Compositions and methods for treating cancer
The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell...
US-9,345,704 Materials and methods for suppressing and/or treating neurofibroma and related tumors
Germline mutations in the NF1 tumor suppressor gene cause Von Recklinghausen's neurofibromatosis type 1 (NF1), a common genetic disorder of the nervous system...
US-9,345,703 Kappa opioid receptor effectors and uses thereof
The present invention is a selective kappa opioid receptor effector, or a pharmaceutically acceptable salt thereof, useful for treating ethanol use disorder...
US-9,345,702 Methods of treatment using selective Bcl-2 inhibitors
This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2...
US-9,345,701 Abuse-resistant controlled-release opioid dosage form
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress...
US-9,345,700 Compositions and methods useful for treating diseases
The present invention relates to a compositions for and methods of cancer treatment in which compounds of Formula I or Formula II. In some aspects, the...
US-9,345,699 Isoquinoline, quinoline, and quinazoline derivatives as inhibitors of hedgehog signaling
The invention provides isoquinoline, quinoline, and quinazoline derivatives to treat a variety of disorders, diseases and pathologic conditions, and more...
US-9,345,698 Alfentanil composition for the treatment of acute pain
There is provided pharmaceutical compositions for the treatment of pain e.g. short-term pain, which compositions comprise a mixture comprising: (a)...
US-9,345,697 Methods of treatment of non-histaminic pruritus
Described herein are methods of treating a mammal in need of treatment for non-histaminic pruritus by administering to the mammal in need thereof a...
US-9,345,696 Methods for treating nicotinic acetylcholine receptor associated diseases
The present invention provides methods and compositions for treating subjects suffering from a disorder associated with a nicotinic acetylcholine receptor...
US-9,345,695 Pharmaceutical compositions for the coordinated delivery of NSAIDs
The present invention is directed to drug dosage forms that release an agent that raises the pH of a patient's gastrointestinal tract, followed by a...
US-9,345,694 Compounds for enhancing arginase activity and methods of using same
The present invention relates to a method for enhancing arginase activity in a damaged or injured cell. In other aspects, the invention provides a method for...
US-9,345,693 Modulators of aldehyde dehydrogenase activity and methods of use thereof
The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the...
US-9,345,692 Pharmaceutical formulations: salts of ...
Pharmaceutical formulations containing salts of (5S,8S)-8-[{(1R)-1-(3,5-Bis-(trifluoromethyl)phenyl]-ethoxy}-methyl]-8-ph- enyl-1,7-diazaspiro[4.5]decan-2-one,...
US-9,345,691 Beta-lactam compounds for enhancing T cell-mediated immune responses
Compositions and methods are provided, comprising at least one beta-lactam compound selected from the group consisting of cefuroxime, a penicillin, ceftriaxone,...
US-9,345,690 Compounds and methods for treating influenza
This invention is directed to methods for treating and preventing influenza infection by inhibiting influenza virus HA maturation processes employing compounds...
US-9,345,689 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N, ...
The invention relates to a pharmaceutical composition comprising a first pharmacologically active ingredient selected from ...
US-9,345,688 KCNQ channels as therapeutic targets
The present disclosure relates to methods and compositions for modulating the activity of KCNQ channels as a means for reducing the effects of aberrant KCNQ...
US-9,345,687 Pharmaceutical compositions of anisomelic acid and the use thereof
A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The...
US-9,345,686 Macrocyclic lactone drug delivery system
Disclosed is a drug delivery system from which a macrocyclic lactone can be released with a desirable zero order release profile. The system is based on the use...
US-9,345,685 Methods for Alzheimer's Disease treatment and cognitive enhancement
The present invention relates to compositions comprising a combination of PKC activators and PKC inhibitors and methods to modulate .alpha.-secretase activity;...
US-9,345,683 Pharmaceutical composition of taxoids
The present invention relates to a stable oral pharmaceutical composition with improved solubility and bioavailability; comprising a taxoid, a solubilizer, a...
US-9,345,682 Inhibition of STAT3 signal transduction for human cancer therapy
Signal Transducer and Activator of Transcription (STAT) proteins have a fundamental role cell signaling, and are activated by a large number of cytokines and...
US-9,345,681 Anti-obesity agent comprising high-purity EPA
The present invention provides an agent for preventing the increase in a body weight (or for decreasing a body weight) or an anti-obesity agent each comprising...
US-9,345,680 Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field
The present invention relates to compounds comprising the general formula (I), in which R.sub.1 and R.sub.2, which may be identical or different, are selected...
US-9,345,679 High-loading, controlled-release magnesium oral dosage forms and methods for making and using same
Disclosed are high loading, controlled-release dosage forms for oral administration of magnesium salts. For example, an oral dosage form can comprise from about...
US-9,345,678 Prostanoid receptor agonist compounds and methods of use for same
Embodiments described herein are directed to prostanoid (IP) receptor agonist compounds, including cicaprost and certain prodrugs, and methods of preparation...
US-9,345,677 Compositions, methods and kits relating to HER-2 cleavage
The present invention relates to compositions, methods and kits based on the ADAM-mediated cleavage of Her-2. The present invention also relates to treatments...
US-9,345,676 Method of treating stroke comprising administering metal chelators to the upper one-third of the nasal cavity
Methods for treating the animal central nervous system against the effects of stoke, including associated cognitive, behavioral and physical impairments....
US-9,345,674 Compositions for treatment of skin and ear infections
The present invention relates to a composition for the treatment of skin and ear infections in humans and animals such as dogs, cats and horses. In particular,...
US-9,345,673 Anti-cancer cycloalkyl diamines
The invention is directed to a method of treatment of a cancer, in a mammal, the method comprising administering to said mammal in need of such treatment an...
US-9,345,672 Ubiquinol and alpha lipoic acid compositions
The present invention is directed to compositions and methods of delivery of CoQ that is reduced in the presence of lipoic acid and, optionally a fatty acid...
US-9,345,671 Adiponectin production enhancer
The present invention provides a pharmaceutical composition for enhancement of adiponectin production, treatment or prevention of hypoadiponectinemia, and the...
US-9,345,670 Patch preparation
The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug...
US-9,345,669 Biodegradable natural films based on co-products derived from industrial-scale seed-treatment processes
A biodegradable film (4) characterized in that it is prepared from at least one co-product derived from a soya bean-processing process aimed at obtaining...
US-9,345,668 Implantable device having a slow dissolving polymer
The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
US-9,345,667 Particles having hydrophobic material therein
A process for preparing particles having a hydrophobic material therein is disclosed. The process comprises providing a multiple emulsion comprising a first...
US-9,345,666 Spray foam corticosteroid product
A foamable pharmaceutical composition and a method of treating corticosteroid-responsive dermatoses of the skin are disclosed. The foamable pharmaceutical...
US-9,345,665 Reduction of flake-like aggregation in nanoparticulate active agent compositions
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising...
US-9,345,664 Process for preparing a medicament
The present invention provides a process for preparing a particulate medicament that has greater homogeneity and a lower adhesion between the particles of the...
US-9,345,663 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by...
US-9,345,662 Degradable hydrogel compositions and methods
This invention concerns an in situ biodegradable hydrogel drug delivery system in which the components are assembled in a manner that provides a mechanism for...
US-9,345,661 Subcutaneous anti-HER2 antibody formulations and uses thereof
The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-HER2 antibody, such as e.g....
US-9,345,660 Micro-emulsions for the treatment of rheumatic disorders
A formulation to treat rheumatic disorders and related infections is provided. The formulation is a micro-emulsion including at one or more of an active...
US-9,345,659 Use of melicope extracts to improve conditions caused by excess lipids
Methods of using extracts of Melicope to impart anti-lipid benefits to skin and/or improve skin conditions resulting from an over-production of lipids.
US-9,345,658 Hair colouring method
Method for coloring hair wherein a first and a second hair coloring composition are applied to the hair, wherein the concentration of the oxidative dye...
US-9,345,657 Compositions containing a silicon resin and a tackifying agent
The invention relates to a composition, especially a cosmetic composition, comprising at least one silicon resin comprising at least one T unit and at least one...
US-9,345,656 Acrylic polymer
The present invention relates to acrylic emulsion polymers as well as to their use in hair care preparations such as in particular in hair styling preparations.
US-9,345,655 Oral care compositions
Aqueous oral compositions containing a cationic steroidal compound and a quaternary ammonium compound are suitable for treating conditions of the oral cavity.
US-9,345,654 Hair dye product
The invention relates to a hair dye product, in particular to a hair dye product comprising at least two natural dye substances, and the use of the at least two...
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