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Patent # Description
US-9,364,533 Polyanionic polymer adjuvants for Haemophilus influenzae B saccharide vaccines
The present invention relates to methods of reducing flocculation in an immunogenic composition, where said immunogenic composition comprises (a) Haemophilus...
US-9,364,532 Compositions and methods for glioblastoma treatment
The present disclosure concerns an oncolytic virus for the treatment of cancer, such as in brain cancer, for example glioblastoma. The oncolytic virus may...
US-9,364,531 Immunostimulatory oligodeoxynucleotides
The present invention relates to immunostimulatory oligodeoxynucleotides, vectors and vaccines comprising such oligodeoxynucleotides, to their use as a...
US-9,364,530 Virus-like particles comprising a matrix protein from a plant enveloped virus and uses thereof
The present invention relates to novel virus-like particles (VLPs) comprising a matrix protein derived from a first plant enveloped virus and a surface...
US-9,364,529 Truncated L1 protein of human papillomavirus type 18
The invention relates to a truncated L1 protein of the Human Papillomavirus Type 18, a virus-like particle consisting of the protein, a vaccine comprising said...
US-9,364,528 Combination neisserial compositions
Compositions comprising a first biological molecule from a Neisseria bacterium and a second biological molecule from a Neisseria bacterium. The term "biological...
US-9,364,527 Bovine vaccines and methods
Methods for stimulating immune responses in a bovine animal susceptible to infection by Leptospira hardjo-bovis are disclosed. In the methods, a composition of...
US-9,364,526 Diagnostic, therapeutic and a vaccine against treponemes
The development of a diagnostic, therapeutic and making and administering a vaccine against ungulate diseases which involves spirochete bacteria in particular,...
US-9,364,525 Vaccines for malaria
The present invention relates to a novel lipoprotein particle, methods for preparing and purifying the same, its use in medicine, particularly in the prevention...
US-9,364,524 Pharmaceutical composition using gonadotropin-releasing hormone (GNRH) combined variants as immunogen
A pharmaceutical composition using natural gonadotropin--releasing hormone (GnRH), and/or some of its mimetic peptides, indistinctly bound by its amino or...
US-9,364,523 Chimeric nucleic acid molecule with non-AUG translation initiation sequences
The present disclosure relates to nucleic acid vaccine compositions and methods for preventing or treating pathological conditions, such as cancer or infectious...
US-9,364,522 Modulation of T cell signaling threshold and T cell sensitivity to antigens
MicroRNAs (miRNAs) are a diverse and abundant class of .about.22-nucleotide (nt) endogenous regulatory RNAs that play a variety of roles in animal cells by...
US-9,364,521 Human tissue kallikrein 1 glycosylation isoforms
Provided are preparations of tissue kallikrein-1 (KLK1) glycoforms having a defined number of oligosaccharide units per KLK1 molecule. Also provided are...
US-9,364,520 Factor VIII conjugates
This invention relates to Factor VIII muteins that are covalently bound, at a predefined site that is not an N-terminal amine, to one or more biocompatible...
US-9,364,519 Pharmaceutical composition for use in the treatment of a neurodegenerative disease
The present application relates to a pharmaceutical composition for use in the prevention or/and treatment of a neurodegenerative disease, the composition...
US-9,364,518 Pharmaceutical composition containing goserelin for in-situ implant
The present invention provides a pharmaceutical composition capable of forming in-situ implant comprising goserelin or its pharmaceutically acceptable salts...
US-9,364,517 Method of treatment of lymphoma with pegylated IL-10
Provided are methods of treatment for tumors. In particular, methods are provided for use of a chemically modified IL-10 to treat tumors.
US-9,364,516 Treatment of fibrosis-related disorders using fibronectin binding proteins and polypeptides
The present invention is directed to various uses of fibronectin binding proteins or polypeptides for treating and preventing fibrosis and fibrosis related...
US-9,364,515 Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
The present invention is directed to a method of treating a patient suffering from the metabolic syndrome and/or related disorders including obesity, Type 2...
US-9,364,514 Anti-tumor adjuvant therapy
A chimeric peptide construct having a cell penetrating peptide linked to a pro-apoptotic peptide. The construct can be used for treating a tumor in combination...
US-9,364,513 Compositions and methods for promoting hemostasis and other physiological activities
Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include...
US-9,364,512 Aloe vera based vaping compositions
An aloe vera based liquid composition comprising at least one antioxidant agent that reduces oxidative stress in the lungs and delivers various antioxidants and...
US-9,364,511 Antiviral preparations obtained from a natural cinnamon extract
The present application provides a natural aqueous extract obtainable from a cinnamon bark (Cinnamon sp.) which has antiviral activity against enveloped viruses...
US-9,364,510 Botanical composition and methods of manufacture and use
A botanical composition and combinations thereof that include a leaf extract of Hylotelephium spectabile (Boreau) H. Ohba and is useful for treating and/or...
US-9,364,509 Therapeutic uses of mastic gum fractions
The invention relates to therapeutic uses of gum mastic, and compounds found therein including polymeric myrcene. More particularly, the invention relates to...
US-9,364,508 Inhibitors of extracellular proteases
Provided is a plant derived extract including inhibitory activity against one or more extracellular proteases which degrade human tissue matrix. Moreover, the...
US-9,364,507 Probiotic enhancement of steroid and immune suppressor activity in mammals with chronic diseases
This invention relates to use of probiotics, particularly P acidilactici and S boulardii, for use in conjunction with steroids and other immune suppressor...
US-9,364,506 Methods of modulating smooth muscle cell proliferation and differentiation
The present disclosure provides methods of inducing smooth muscle cell differentiation. The present disclosure provides genetically modified cells comprising...
US-9,364,505 Therapeutic composition for treatment of glioblastoma
The present invention is directed to compositions and methods for treating an animal diagnosed with Glioblastoma multiforme (GBM).
US-9,364,504 Compostition and therapeutic anti-tumour vaccine
The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumor...
US-9,364,503 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one...
US-9,364,502 Gallium nitrate formulations
The present invention relates to stable pharmaceutical formulations that include a delivery agent and/or pharmaceutically acceptable salt thereof.
US-9,364,501 Chlorite in the treatment of neurodegenerative disease
The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease...
US-9,364,500 Compositions for treating cancer with combinations of histone deacetylase inhibitors (HDAC1) substances
A method for treating cancer is described using combination therapies comprising the use of hyperbaric oxygen with histone deacetylase inhibitors, with and...
US-9,364,499 Use of dextran sulfate
A graft composition intended for transplantation into a patient comprises an injection solution comprising an isolated cell transplant and dextran sulfate, or a...
US-9,364,498 Heparin prodrugs and drug delivery stents formed therefrom
A prodrug comprising a heparin and a drug is provided. The prodrug can be used to form a coating on a medical device. The prodrug can also be used with a...
US-9,364,497 Treatment of cognitive disorders
The invention relates to treatments of cognitive disorders e.g. Mild Cognitive Disorder comprising the use of agents which are capable of lowering homocysteine...
US-9,364,496 Custirsen treatment with reduced toxicity
The present invention provides a method for providing antisense therapy which reduces the expression of clusterin to provide therapeutic benefit in the...
US-9,364,495 Oral delivery of therapeutically effective LNA oligonucleotides
The invention provides for LNA oligomers, for the treatment of a metabolic or liver disorder, wherein the LNA oligomer is administered orally in a unit dose of...
US-9,364,494 Somatostatin 2 receptor (sst2), deoxycytidine kinase (dck) and uridine monophosphate kinase (umk) pancreatic...
The present invention concerns products containing (i) at least one nucleic acid sequence coding for the human somatostatin 2 receptor protein (sst2) having the...
US-9,364,493 Methods and compositions for enhancing the uptake of therapeutic agents by target cells
The present invention relates to a new use of a known medicament. Specifically, the invention relates to methods and compositions for enhancing the therapeutic...
US-9,364,492 Method for glycosylation of flavonoid compounds
The present invention provides a method for preparing a glycoside of a flavonoid compound, which comprises the step of treating flavonoid and a glycosyl donor...
US-9,364,491 Antimicrobial compositions with cysteamine
The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic...
US-9,364,490 Use of derivatives containing C--O--P bonds in patients with kidney failure
Use of a derivative containing C--O--P bonds in a controlled release form to treat patients with kidney failure. Moreover, it comprises the use of said...
US-9,364,489 Crystals and process of making 5-({[2-amino-3-(4-Carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-- ...
The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-- ...
US-9,364,488 Myelin regeneration with androgens
Methods for effective remyelination in patients are disclosed comprising treating the patient with an androgen receptor ligand which exerts binding to androgen...
US-9,364,487 Dermal delivery compositions and methods
A composition for transdermal delivery of a progestin for progestin hormone therapy is disclosed. Also disclosed is a transdermal delivery device comprising the...
US-9,364,486 6-substituted estradiol derivatives for use in remyelination of nerve axons
Disclosed is a method of remyelinating axons with 6-substituted estradiol compounds of the formula ##STR00001## The methods can be used to treat a variety of...
US-9,364,485 Topical formulations comprising a steroid
The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are...
US-9,364,484 Methods and compositions for treating viral diseases
The invention provides a method for treating viral infections and coinfections through the use of inhibitory agents that prevent a unique viral structural...
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