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Patent # Description
US-9,365,541 Compounds for use in the treatment of parasitic diseases
The present invention relates to compounds useful for treating parasitic diseases, which are infectious diseases caused or transmitted by a parasite. Compounds...
US-9,365,540 Benzimidazole derivatives as MCH receptor antagonists
The present invention provides an aromatic ring compound having a melanin-concentrating hormone receptor antagonistic action and useful as an agent for the...
US-9,365,539 Prolylcarboxypeptidase inhibitors
Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and...
US-9,365,538 Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione
Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of...
US-9,365,537 Process for recycling polyacetals
A process for recycling polyoxymethylene polymers is disclosed. A polyoxymethylene polymer is at least partially dissolved in an aprotic compound. The resulting...
US-9,365,536 Method for producing glycolide, which is provided with rectification step by means of gas-liquid countercurrent...
A method for producing glycolide provided with: step (1) wherein a GAO composition, which preferably contains a high-boiling-point organic solvent or a...
US-9,365,535 Process for the preparation of alkylene glycol
The invention provides a process for the preparation of an alkylene glycol from an alkene. A gas composition from an alkylene oxide reactor is supplied to an...
US-9,365,534 Arylated camphenes, processes for their preparation and uses thereof
The present invention relates to arylated camphenes, processes for their preparation and uses thereof for the manufacture of medicaments for the treatment of...
US-9,365,533 Coumarin derivative
A novel coumarin derivative or a pharmaceutically acceptable salt thereof and also to provide a pharmaceutical agent containing such a compound as an active...
US-9,365,532 Synthesis, composition and use of novel therapeutic and cosmetic Schiff base products formed by reaction of a...
The present invention relates to the synthesis, composition and use of novel moieties formed by reacting a transimination nucleophilic catalyst, molecular or...
US-9,365,531 Method for selectively oxidizing 5-hydroxymethyl furaldehyde
A method for oxidizing 5-hydroxymethyl furaldehyde, includes at least one step of oxidation in the presence of an organic acid, a nitroxyl radical, an oxygen...
US-9,365,530 Direct anti-markovnikov addition of acids to alkenes
A method of making an anti-Markovnikov addition product is carried out by reacting an acid with an alkene or alkyne in a dual catalyst reaction system to the...
US-9,365,529 Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof...
US-9,365,528 Derivatives of sulindac, use thereof and preparation thereof
Derivatives of sulindac that lack cyclooxygenase inhibitory activity are provided along with pharmaceutical compositions containing them and use for treatment...
US-9,365,527 Arginine methyltransferase inhibitors and uses thereof
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present...
US-9,365,526 Process for the preparation of dasatinib and its intermediates
The present invention relates to processes for the preparation of dasatinib and its intermediates.
US-9,365,525 System and method for extraction of chemicals from lignocellulosic materials
An organosolv process for producing bio-products by decomposing lignocellulosic materials comprises providing an initial lignin solvent with water, an acid, and...
US-9,365,524 Solid forms of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyri- ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
US-9,365,523 Imidazolyl amide compounds and uses related thereto
This disclosure relates to antiviral compounds disclosed herein and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical...
US-9,365,522 Pyrazole amide derivative
The present invention relates to a novel compound having a function of inhibiting ROR.gamma. activity. The present invention also relates to pharmaceutical...
US-9,365,521 Non-hygroscopic salts of 5-HT.sub.2C agonists
Salts of the 5-HT.sub.2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter...
US-9,365,520 Heterocyclic compound
The present invention provides a heterocyclic compound having a ROR.gamma.t inhibitory action. The present invention relates to a compound represented by the...
US-9,365,519 PRMT5 inhibitors and uses thereof
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present...
US-9,365,518 6-aminoisoquinoline compounds
6-Amino isoquinoline compounds are provided that influence, inhibit or reduce the action of a kinase. Pharmaceutical compositions including therapeutically...
US-9,365,517 3-cyano-quinoline derivatives with antiproliferative activity
The present invention concerns the compounds of formula ##STR00001## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically...
US-9,365,516 Process for preparing quinoline derivatives
A process for preparing a compound of Formula I is disclosed: ##STR00001## wherein: R.sup.1 is halo; R.sup.2 is halo; R.sup.3 is (C.sub.1-C.sub.6)alkyl or...
US-9,365,515 Oxime ester photoinitiators
Oxime ester compounds of formula (I), wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, and R.sub.10 independently of...
US-9,365,514 Composition comprising tetracyclic compound
A composition which comprises substance represented by Formula (I), ##STR00001## [Meanings of the symbols that are included in the formula are given in the...
US-9,365,513 Fullerene derivative, and method of preparing the same
A fullerene derivative having 60 or more carbon atoms, includes at least one specific structure.
US-9,365,512 Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
The present invention relates to isoindoline derivatives of the formula (I) ##STR00001## or a physiologically tolerated salt thereof. The present invention...
US-9,365,511 Biphenyl-ethyl-pyrrolidine derivatives as histamine H3 receptor modulators for the treatment of cognitive disorders
The present invention relates to compounds of Formula (Ia) and pharmaceutically acceptable salts, solvates, and hydrates thereof, that modulate the activity of...
US-9,365,510 Aziridine bisphenol ethers and related compounds and methods for their use
Compounds having a structure of Formula I: ##STR00001## or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, R.sup.1, R.sup.2,...
US-9,365,509 Continuous on-line adjustable disinfectant/sanitizer/bleach generator
Methods and systems for on-site, continuous generation of peracid chemistry, namely peroxycarboxylic acids and peroxycarboxylic acid forming compositions, are...
US-9,365,508 Aroyl thiourea derivatives
The invention provides compounds according to formula (I): (wherein X, Y, Z1 R1, R2, R3, Ar and Ar' are as defined herein), and physiologically acceptable...
US-9,365,507 Diaryl sulfone compound, and manufacturing method for same
The present invention provides a diaryl sulfone compound represented by Formula (1): ##STR00001## wherein R.sup.1 to R.sup.4 and R.sup.1' to R.sup.4' are the...
US-9,365,506 Compounds and compositions as TLR2 agonists
The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such...
US-9,365,505 Photoresist monomer, photoresist and method for the preparation thereof, color filter
A photoresist monomer, a photoresist and a method for the preparation thereof, a color filter. The photoresist monomer has a structure represented by Formula I,...
US-9,365,504 Salts of kukoamine B, preparation method and use thereof
Salts of kukoamine B, their preparation method and their pharmaceutical use in preparation of drugs for preventing and treating sepsis. Experiments indicate...
US-9,365,503 Process for the preparation of isocyanates in the gas phase
Meta-toluene-diisocyanate is produced by reacting meta-toluenediamine with phosgene in the gas phase. The meta-toluenediamine to be vaporized for use in this...
US-9,365,502 Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
The present disclosure is generally directed to neuroactive substituted cyclopenta[b]phenanthrenes as referenced herein, and pharmaceutically acceptable salts...
US-9,365,501 Stable polymerizable UV-absorbing colorant for intraocular lens
A polymerizable UV-absorbing colorant monomer is provided, which is excellent in stability under alkaline conditions and which is available for a useful...
US-9,365,500 9-aminomethyl substituted minocycline compounds
The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous...
US-9,365,499 9-aminomethyl substituted tetracycline compounds
The present invention relates to 9-aminomethyl substituted tetracycline compounds represented by formula (I), or pharmaceutically acceptable salt, prodrug,...
US-9,365,498 Inhibitors of histone deacetylase
The present invention relates to compounds of formula (I): ##STR00001## or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein U,...
US-9,365,497 Rubber composition comprising a hydrate of a compound or a methanol solvate of a compound
A rubber composition comprising a hydrate of a compound represented by formula (I-2) or a salt thereof; or a methanol solvate of a compound represented by...
US-9,365,496 iNKT cell modulators and methods of using the same
Disclosed herein are .alpha.-galactosylceramide (.alpha.-GalCer) analogs and compositions thereof, methods of activating invariant Natural Killer T (iNKT) cells...
US-9,365,495 Process for manufacturing aryloxyacetamides
The present invention relates to a process for manufacturing aryloxyacetamides of formula (I), ##STR00001## by reacting haloacetamides of formula (II) with a...
US-9,365,494 Process for synthesis of amino-methyl tetralin derivatives
Methods for producing a compound of formula k1 or k2 ##STR00001## by reducing a dihydronapthalene amide compound of formula i ##STR00002## with hydrogen gas...
US-9,365,493 Synthesis of tetracyclines and analogues thereof
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the...
US-9,365,492 2-(ethylamino)ethanol production method
The present invention relates to a production method for 2-(ethylamino)ethanol, including subjecting N-ethyldiethanolamine to a disproportionation reaction in...
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