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Patent # Description
US-9,376,705 Method for detecting susceptibility of microorganisms to chemical agents
A method for detecting susceptibility of microorganisms to chemical agents or antibiotics through a combination of exposing the microorganisms to the chemical...
US-9,376,704 Test kit and method for detecting bacteriophage
Phages can be detected as rapid indicators of the hygienic quality of a sample. Both continuous flow methods and devices, single sample methods and devices, of...
US-9,376,703 Methods for detecting a xerophilic or osmophilic yeast or mold microorganism
A method for detecting a xerophilic microorganism is provided. The method comprises providing a sample to be tested, an aqueous diluent comprising about 1.0 to...
US-9,376,702 Regulating the production of isoprenoids in algal cells
The invention relates to a method for increasing the production level of isoprenoids in an algal cell. The method includes increasing expression of a...
US-9,376,701 Method for secretory production of protein
A novel technique for improving secretory production of a heterologous protein by coryneform bacteria is described, and thereby a method for secretory...
US-9,376,700 Methods of modifying N-termini of a peptide or protein using transferases
The invention includes a selective method of modifying the N-terminus of a protein using an aminoacyl tRNA transferase. In certain embodiments, the method...
US-9,376,699 Methods of producing hybrid antibodies
A method for engineering and utilizing large DNA vectors to target, via homologous recombination, and modify, in any desirable fashion, endogenous genes and...
US-9,376,698 Mutant DNA polymerases
An isolated mutant Tfi DNA polymerase having a D144A point mutation. This polymerase may be used in methods including, but not limited to, nucleic acid...
US-9,376,697 On-farm integrated high-solids processing system for biomass
A method for on-farm processing a biomass feedstock into a useful industrial chemicals includes the steps of (a) delignifying the biomass feedstock to produce a...
US-9,376,696 Compositions and methods for producing benzylisoquinoline alkaloids
The present invention relates to host cells that produce compounds that are characterized as benzylisoquinolines, as well as select precursors and intermediates...
US-9,376,695 L-amino acid producing bacterium
A method for producing an L-amino acid is described, for example, L-phenylalanine and L-histidine, by fermentation using a bacterium of the Enterobacteriaceae...
US-9,376,694 Method for preparing optically active amino acid using cosubstrate shuttling of transaminase
The present disclosure relates to a method for preparing an optically active amino acid using cosubstrate shuttling of transaminase. The method includes...
US-9,376,693 Pre-treated biomass having enhanced enzyme accessibility
This invention is to a biomass composition of 5 and 6 carbon sugars, lignin, and cellulose which has been steam exploded and the composition has a very high...
US-9,376,692 Process for rapid anaerobic digestion of biomass using microbes and the production of biofuels therefrom
A process for effecting anaerobic digestion of plant biomass, which entails the step of anaerobically digesting plant biomass with at least one species of rumen...
US-9,376,691 Fusion proteins useful for producing pinene
The present invention provides for a modified host cell comprising a heterologous pinene synthase (PS), or enzymatically active fragment or variant thereof, and...
US-9,376,690 Templated nanoconjugates
The present disclosure is directed to compositions comprising templated nanoconjugates and methods of their use.
US-9,376,689 Engineered cleavage half-domains
Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the...
US-9,376,688 Method of producing cyclamen with multi-petaled flowers
A method of producing a multi-petaled cyclamen plant having an increased number of petals, including at least inhibiting the function of a transcription factor...
US-9,376,687 Algal elongase 6
Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having elongase activity, which utilize fatty acids as substrates.
US-9,376,686 Vaccine and therapeutic delivery system
The present invention relates to a new vaccine delivery system. In particular, the present invention includes compositions and methods of integrally transformed...
US-9,376,685 Linear donor constructs for targeted integration
Disclosed herein are linear donor molecules comprising homology arms of 50-750 base pairs (e.g., 50-100 base pairs) flanking one or more sequences of interest....
US-9,376,684 Anticoagulant fusion protein anchored to cell membrane
The invention relates to the inhibition of blood coagulation, especially during organ rejection, and in particular the inhibition of delayed vascular rejection....
US-9,376,683 Organic compositions to treat beta-ENaC-related diseases
The present disclosure relates to RNAi agents useful in methods of treating BetaENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1...
US-9,376,682 Method of treating pulmonary disease by administering an antibody to G-CSF
The present invention relates generally to a method for treating or preventing or otherwise ameliorating the effects of pulmonary diseases characterized by or...
US-9,376,681 miR-29 mimics and uses thereof
The present invention relates to synthetic oligonucleotide mimetics of miRNAs. In particular, the present invention provides double-stranded, ...
US-9,376,680 Serpinc1 iRNA compositions and methods of use thereof
The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the Serpinc1 gene, and methods of using such iRNA, e.g.,...
US-9,376,679 Microvesicles carrying small interfering RNAs, preparation methods and uses thereof
Microvesicles containing interfering RNAs, preparation methods and uses thereof are provided. Pharmaceutical compositions and kits comprising the microvesicles...
US-9,376,678 Method of preparing libraries of template polynucleotides
The present invention relates to a method for preparing a library of template polynucleotides and use thereof in methods of solid-phase nucleic acid...
US-9,376,677 Arrays and methods of use
Methods are provided for producing a molecular array comprising a plurality of molecules immobilized to a solid substrate at a density which allows individual...
US-9,376,676 Method of breaking down biological material
In various embodiments, a method of breaking down biological material is provided. The method may include providing a sample comprising the biological material...
US-9,376,675 Method for preserving components of pancreatic juice in a sample, and kit for preserving components of...
The present invention provides a method for preserving biological components in pancreatic juice, and a kit suited for this method. The method involves adding,...
US-9,376,674 Process to prepare a stable thrombin composition
The stable thrombin composition comprises purified thrombin, human albumin and a neutral salt, the resulting product being stable when stored as a lyophilisate...
US-9,376,673 Beta-lactamases with improved properties for therapy
This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (GI tract)...
US-9,376,672 Coagulation factor IX compositions and methods of making and using same
The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids...
US-9,376,671 Method of making protease that decomposes proteins recalcitrant to proteolysis with Streptomyces
The invention provides novel biologically pure cultures of microorganisms high in protease activity and capable of decomposing proteins recalcitrant to...
US-9,376,670 Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and polynucleotides encoding the polypeptides. The invention also...
US-9,376,669 Methods and products for expressing proteins in cells
The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to...
US-9,376,668 Fagopyritol synthase genes and uses thereof
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin...
US-9,376,667 Protein having NADH and/or NADPH oxidase activity
Water-forming NADH oxidase derived from Streptococcus mutans should be further improved in terms of stability for practical use in industrial production. An...
US-9,376,666 Nanofibers with high enzyme loading for highly sensitive biosensors
The invention provides high enzyme loading nanofibers and processes utilized in their fabrication, the nanofibers suitable for use as a new class of highly...
US-9,376,665 Method for producing intestinal cells
An object of the present invention is to provide a method of producing intestinal cells by use of pluripotent stem cells as a starting material. According to...
US-9,376,664 Reprogramming of cells to a new fate
Methods and compositions for transdifferentiation of an animal cell from (i) a first pluripotent cell fate to a second nonpluripotent cell fate or (ii) from a...
US-9,376,663 GPR15-mediated homing and uses thereof
The present invention is directed to in vitro methods for promoting expression of G-protein coupled receptor 15 (GPR15) on T cells, GPR15+ enriched populations...
US-9,376,662 Increasing cell culture population doublings for long-term growth of finite life span human cell cultures
Cell culture media formulations for culturing human epithelial cells are herein described. Also described are methods of increasing population doublings in a...
US-9,376,661 Method for culture of corneal endothelial cells, process for production of corneal endothelial cell sheet for...
The invention provides a method of culturing a corneal endothelial cell by use of a culture medium containing an ascorbic acid derivative and the like.
US-9,376,660 Method for increasing the CoQ10 and CoQH2 content in phototrophic microorganisms
A method for increasing the content of ubiquinone (CoQ10) and ubiquinol (CoQH2) in phototrophic microorganisms that were cultivated in a culture medium in a...
US-9,376,659 Personal care composition containing yeast/polyphenol ferment extract
Disclosed is a yeast/polyphenol ferment extract, and a personal care composition including the yeast/polyphenol ferment extract. Also disclosed is a method for...
US-9,376,658 Cell culture array system for automated assays and methods of operation and manufacture thereof
A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for...
US-9,376,657 Culture device
A culture device containing a culture vessel for culturing a cell, in which the culture device includes a thermostatic vessel having a stacker containing a...
US-9,376,656 Photobioreactor system and method for the growth of algae for biofuels and related products
A photobioreactor includes an upper layer of transparent film and a lower layer of film wherein the upper layer and lower layer are attached to each other along...
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