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Patent # Description
US-9,381,255 Formulations comprising T3 nanoparticles
Nanoparticles comprising T3 and their use in treating, e.g., cardiac conditions, for example cardiac arrest, are provided. Such nanoparticles provide improved...
US-9,381,254 Methods for preparing polymeric reagents
The present invention provides among other things methods for preparing polymeric reagents, wherein the method comprises (a) providing an aromatic moiety...
US-9,381,253 Drug delivery polymer and uses thereof
Described herein are platinum-based brush-arm star polymers (Pt-BASPs), or a pharmaceutical composition thereof, for delivery of platinum-based agents, such as...
US-9,381,252 Nanoparticles for encapsulation of compounds, the production and uses thereof
The present invention relates to nanoparticles for the encapsulation of compounds, the obtaining and uses thereof. The nanoparticles comprise a zein matrix and...
US-9,381,251 Thermoplastic paste for repairing living tissues
This invention relates to a thermoplastic paste with a highly thixotropic rheology, the components of which are a block biopolymer and a bioceramic. The...
US-9,381,250 Crosslinked polysaccharide beads and their biomedical uses
The present inventions relates to beads as biocompatible material adapted for use within the human or animal body. Said beads are highly useful for tissue...
US-9,381,249 Compositions comprising apomorphine and organic acids and uses thereof
The present invention provides stable liquid or semi-solid pharmaceutical compositions of apomorphine, more particularly compositions comprising apomorphine and...
US-9,381,248 Coating agent for pharmaceutical solid preparation, pharmaceutical film formulation, and coated pharmaceutical...
A coating agent for a pharmaceutical solid preparation imparts an unpackaged pharmaceutical solid preparation with excellent barrier properties equivalent to...
US-9,381,247 Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs,...
Compositions and methods for modulating injection site pain associated with rapid acting injectable insulin formulations have been developed for subcutaneous...
US-9,381,246 Cancer therapy
The present application relates to compositions and methods for treating a proliferative disorder by administering to a subject a pharmaceutical composition of...
US-9,381,245 Methods for inhibiting osteolysis
The invention provides methods and compositions for reducing or inhibiting osteolysis, bone resorption, osteoclast differentiation and stimulation and the...
US-9,381,244 VISTA modulators for diagnosis and treatment of cancer
The present disclosure relates to compositions and therapeutic methods for activating an immune response in a patient in need thereof. In a preferred...
US-9,381,243 Methods of identifying critically ill patients at increased risk of development of organ failure and compounds...
The present invention relates to compounds for treatment that protects the endothelium, prevents pathologic thrombus formation in the microcirculation and...
US-9,381,242 Adjuvant composition containing citrulline
A novel adjuvant composition is provided that is excellent in safety and convenience as compared to the conventional adjuvant such as Alum. An adjuvant...
US-9,381,241 Mucosal adjuvant composition
Problem to be Solved: The present invention provides a novel mucosal adjuvant. Solution: The present invention provides a mucosal adjuvant composition...
US-9,381,240 Recombinant low virulence bovine herpesvirus-1 (BoHV-1) vaccine vectors
The present disclosure teaches generally in the field of vaccination and disease control in cattle and bovine animals. A recombinant bovine herpesvirus 1...
US-9,381,239 VLPS derived from cells that do not express a viral matrix or core protein
The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins...
US-9,381,238 Method for improving the production of influenza viruses and vaccine seeds
The present invention relates to a method for improving the production of an influenza virus, and in particular influenza vaccine seeds, or a vaccine directed...
US-9,381,237 Neutralizing immunogen (NimIV) of rhinovirus and its uses for vaccine applications
The invention relates to methods and compositions for preventing or treating human rhinovirus infection.
US-9,381,236 Interferon-.beta. production modulating listeria strains and methods for using same
Mutant Listeria bacteria that modulate interferon-.beta. production are provided. The subject bacteria are characterized by having a mutation in a gene chosen...
US-9,381,235 Programming of cells for tolerogenic therapies
Biomaterial systems, e.g., gel scaffolds, are used in vivo to recruit immune cells and promote their activation towards a non-inflammatory phenotype, thereby...
US-9,381,234 Methods of using myelin basic protein peptide compositions
The present invention relates to a composition which comprises the following myelin basic protein peptides: MBP 30-44; MBP 83-99; MBP 131-145; and MBP 140-154....
US-9,381,232 Nano-recombinant fibrinogen for fibrin sealants
A fibrin-based hemostatic agent suitable for both civilian and military use is disclosed. The hemostatic agent comprises (i) nanoparticles to which a plurality...
US-9,381,231 Use of relaxin to restore maternal physiology in pregnancies conceived by assisted reproductive technologies
The subject invention relates to methods for improving a subject's vasculature to normalize maternal hemodynamics, particularly in subjects attempting to...
US-9,381,230 Interferon analogs
The invention relates to the field of medicine. Among others, it relates to biologically active analogs of interferons (IFNs) which show less unwanted...
US-9,381,229 Pharmaceutical composition for use in the treatment of dysfunction associated with aging
The present invention relates to an APJ receptor agonist or an apelinomimetic for use in the treatment or the prevention of a dysfunction associated with aging.
US-9,381,228 FKBP-L and uses thereof
Disclosed are methods and compositions that employ FKBP-L polypeptides for modulating angiogenesis and/or tumor metastasis. The FKBP-L polypeptides may be used...
US-9,381,227 Treatment of ischemia
A system, including methods and compositions, for treatment of ischemia.
US-9,381,226 Methods and compositions related to inhibition of viral entry
Disclosed are compositions and methods for inhibiting viral entry.
US-9,381,225 Methods of protecting against apoptosis using lipopeptides
The use of lipopeptides comprising variable groups defined as H or optionally substituted C.sub.6-C.sub.20 aliphatic and a peptide of one of the following amino...
US-9,381,224 Plant based formulation for the prevention and management of metabolic syndrome and cardiovascular disease...
The invention relates to a plant based formulation for the prevention and management of Metabolic Syndrome and Cardiovascular disease mortality risk comprising...
US-9,381,223 Methods for inhibiting advanced glycation end product production, inhibiting fibroblast apoptosis, and/or...
Disclosed is an AGE production inhibitor or the like, which effectively inhibits the production of an advanced glycation end product (AGE), while having...
US-9,381,222 Compositions for preventing and treating obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes or...
The present invention relates to compositions for preventing and treating obesity, hyperlipidemia, atherosclerosis, fatty liver, diabetes or metabolic syndrome...
US-9,381,221 Phytocomposition for the treatment of pain related to joint diseases
It is disclosed a phytocomposition which includes: (a) 0.01 wt % to 26 wt % of Arnica montana extract; (b) 0.01 wt % to 26 wt % of Rosmarinus officinalis...
US-9,381,220 Sceletium extract and uses thereof
A composition including as an active ingredient an extract of a plant of the family Mesembryanthemaceae with mesembrenol and mesembrenone as the two major...
US-9,381,219 Brown adipocyte modification
Methods and therapeutics are provided for treating metabolic disorders by increasing activation of brown adipose tissue. Generally, the methods and therapeutics...
US-9,381,218 Artificial skeletal material and constructs formed therefrom
A bioresorbable skeletal construct member formed from an osteoinductive composition comprising autogenic bone and an extracellular matrix (ECM) material, the...
US-9,381,217 Microgels for encapsulation of cells and other biologic agents
Methods of encapsulating cargo in a microgel droplet, microgel droplets prepared according the provided methods, and methods of use thereof are disclosed. The...
US-9,381,216 Methods of generating, repairing and/or maintaining connective tissue in vivo
This invention relates to a method for generating, repairing and/or maintaining connective tissue in a subject. In one embodiment, the invention relates to a...
US-9,381,215 Compositions and methods for the treatment of cancers
The present invention provides a formulation comprising dichloroacetate and arsenic trioxide. The present invention also provides a method of treating cancer by...
US-9,381,214 Methods for treating skin irritation
The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later...
US-9,381,213 Antiviral and immune stimulant pharmaceutical composition
The invention relates to a novel antiviral and immune-simulating pharmaceutical composition, containing as active ingredient 20-85 mass % of a...
US-9,381,212 Methods of using inhaled nitric oxide gas for treatment of acute respiratory distress syndrome in children
The present invention provides a treatment of acute respiratory distress syndrome (ARDS) in children using dosing of nitric oxide at low concentrations, such as...
US-9,381,211 Composition and method for treating connective tissue damage
The present invention provides a composition, and a method of use thereof, for treating connective tissue damage in man and in animals, which comprises a...
US-9,381,210 Induced pluripotent stem cell model of chronic myeloid leukemia revealed olfactomedin 4 as a novel therapeutic...
Disclosed herein are compositions and methods to treat and reduce therapeutic resistance in chronic myelogenous leukemia. Also disclosed herein are methods to...
US-9,381,209 Treatment of squamous cell carcinoma with HSP27 antisense oligonucleotides and radiotherapy
Squamous cell carcinomas, such as squamous head and neck cancer, are treated with a combination of radio-therapy and a therapeutic agent that reduces the amount...
US-9,381,208 Structure and use of 5' phosphate oligonucleotides
Oligonucleotides bearing free, uncapped 5' phosphate group(s) are recognized by RIG-I, leading to the induction of type I IFN, IL-18 and IL-1.beta. production....
US-9,381,207 Drug formulations
The invention provides derivatives of decitabine with superior chemical stability and shelf life, with similar physiological activity. The derivatives are...
US-9,381,206 Salts of HIV inhibitor compounds
The invention is related to salts of anti-viral compounds, compositions containing such salts, and therapeutic methods that include the administration of such...
US-9,381,205 Anti-EFNA4 antibody-drug conjugates
The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
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