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Patent # Description
US-9,387,249 Methods of treating hypertension with at least one angiotensin II receptor blocker and chlorthalidone
The present invention relates to a method of treating hypertension in a subject or patient needing treatment thereof by administering to said subject or patient...
US-9,387,248 Pharmaceutical composition comprising antibody composition which specifically binds to CCR4
A pharmaceutical composition, comprising an antibody composition which specifically binds to human CC chemokine receptor 4 (hereinafter also referred to as...
US-9,387,247 Monoclonal antibodies to programmed death 1 (PD-1)
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity....
US-9,387,246 Treatment methods for rheumatoid arthritis
The present invention provides methods for selecting treatment methods for rheumatoid arthritis based on an objective selection process (algorithm). The present...
US-9,387,245 Methods and compositions for the inhibition of fructokinase
The invention relates to the use of isoform-specific fructokinase (ketohexokinase) (KHK) inhibitors alone or in combination with various agents to both prevent...
US-9,387,244 Methods for reducing global chronic inflammation and the presence of melanoma
This document relates to methods and materials involved in treating cancer (e.g., melanoma). For example, methods and materials involved in using an...
US-9,387,243 Recombinant protein carrying human papillomavirus epitopes inserted in an adenylate cyclase protein or fragment...
The invention relates to a recombinant protein comprising one or several polypeptides bearing one or several epitopes of one or several HPV antigens, said...
US-9,387,242 Chimeric viruses presenting non-native surface proteins and uses thereof
The present invention provides chimeric negative-stand RNA viruses that allow a subject, e.g., an avian, to be immunized against two infectious agents by using...
US-9,387,241 Influenza virus-like particle (VLP) compositions
Influenza virus-like particles (VLPs) comprising influenza antigenic polypeptides are described. Also described are compositions comprising these VLPs as well...
US-9,387,240 Attenuated negative strand viruses with altered interferon antagonist activity for use as vaccines and...
The present invention relates, in general, to attenuated negative-strand RNA viruses having an impaired ability to antagonize the cellular interferon (IFN)...
US-9,387,239 Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof
The present technology provides vaccine compositions comprising native outer membrane vesicles (NOMVs) from at least one genetically modified strain of...
US-9,387,238 CDCA1 epitope peptides and vaccines containing the same
Peptide vaccines against cancer are described herein. In particular, the present invention describes epitope peptides derived from CDCA1 that elicit CTLs. The...
US-9,387,237 Methods of treating a patient having an autoimmune disorder by administering a soluble BCMA
Therapeutic regimens for administration of BAFF antagonists for treatment of immunologic and related disorders are described. Regimens involve a short-term BAFF...
US-9,387,236 Pharmaceutical compositions containing protease and methods for the treatment of lysosomal storage diseases
The invention provides a method and compositions for treating a subject with a lysosomal storage disease such as gaucher disease, by administering to a subject...
US-9,387,235 Cosmetic preparations containing PTH fragments
A cosmetic or pharmaceutical composition includes a peptide parathyroid hormone fragment, derivatives thereof, salts thereof, and combinations thereof, where...
US-9,387,234 Use of SDF-1 to improve ischemic myocardial function
A method is provided for increasing trafficking of endothelial progenitor cells to an ischemic myocardium in a subject's heart comprising administering to the...
US-9,387,233 Long-term storage of non-glycosylated recombinant human G-CSF
The present invention provides a method for stable long-term storage of non-glycosylated recombinant human Granulocyte-Colony Stimulating Factor (G-CSF),...
US-9,387,232 SorCS1 for the treatment of obesity
The present invention relates to SorCS1-like agents, including SorCS1, nucleic acid molecule encoding expression of SorCS1 and fragments thereof, as well as...
US-9,387,231 Compositions comprising a Brd4 antagonist and methods for the treatment of HIV
Compositions and methods for the treatment of HIV are provided.
US-9,387,230 Methods to treat cancer using cyclosporine and cyclosporine derivatives
Methods to treat certain types of cancer with cyclophilin inhibitors.
US-9,387,229 Reuterin-producing Lactobacillus brevis
The invention relates to reuterin-producing strains of Lactobacillus brevis. These strains are useful in particular for the treatment or the prevention of...
US-9,387,228 Agent for prevention or amelioration of obesity
To provide a pharmaceutical product or food which has an excellent fat-accumulation-inhibiting activity and/or fat-metabolism-improving activity and which is...
US-9,387,227 Method for treatment of sores and lesions of the skin
A composition for the topical treatment of sores, lesions, ulcers, and other disorders of the skin, said composition includes a combination of a bee product and...
US-9,387,226 Neural cell proliferation induced through the culture of neural cells with umbilical cord blood-derived...
A use of a composition comprising umbilical cord blood-derived mesenchymal stem cells for inducing differentiation and proliferation of neural precursor cells...
US-9,387,225 Gold-platinum based bi-metallic nanocrystal suspensions, electrochemical manufacturing processes therefor and...
The present invention relates to novel gold-platinum based bi-metallic nanocrystal suspensions that have nanocrystal surfaces that are substantially free from...
US-9,387,224 Treatment of specific cardiovascular conditions with nitrite
It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues....
US-9,387,223 Ophthalmic compositions comprising povidone-iodine
A topical ophthalmic composition comprised of povidone-iodine 0.01% to 10.0% combined with a steroid or non-steroidal anti-inflammatory drug. This solution is...
US-9,387,222 Alginate biomaterials for the treatment of hepatic disorders
The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention...
US-9,387,221 SDF-1 binding nucleic acids and the use thereof in cancer treatment
The present invention is related to a nucleic acid molecule capable of binding to SDF-1, preferably capable of inhibiting SDF-1, whereby the nucleic acid...
US-9,387,220 Method for inducing hepatocyte proliferation and uses thereof
The present application provides methods and compositions for inducing hepatocyte proliferation and liver regeneration, the latter being mainly dependent on...
US-9,387,219 Edible composition
Foods or meals high in available carbohydrate such as sucrose or starch increase post-prandial blood glucose concentrations. Repeated high post-prandial plasma...
US-9,387,218 Composition for the treatment of inflammatory and immune disorders
The invention relates to the treatment of an inflammatory or immune disorder with a pharmaceutical composition including methylsulphonylmethane, glucosamine and...
US-9,387,217 Acyclic nucleoside phosphonate diesters
The present disclosure relates, inter alia, to compositions and methods for treating viral diseases and cancer. There are disclosed lipophilic antiviral and...
US-9,387,216 Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
Described herein are methods and compositions for the treatment of prostate cancer in a subject in need thereof. The prostate cancer may be a castration...
US-9,387,215 Animal feed including cationic cholesterol additive and related methods
Methods and feed compositions for increasing health of agricultural animals include administering a cationic cholesterol additive through the diet of the...
US-9,387,214 Method of identifying therapies for pulmonary hypertension
The present invention is directed to a method of screening for a therapeutic agent useful for treating pulmonary hypertension comprising: contacting an...
US-9,387,213 Small molecules inhibiting oncoprotein Myc
Pharmaceutical compositions including a Myc inhibitor are provided. Also provided are methods for treating cancer including administration of compounds that...
US-9,387,212 Methods for treating Parkinson's disease
The invention pertains to a method of treating Parkinson's disease (PD) in a mammal, comprising administering a first pharmaceutical agent and a second...
US-9,387,211 Methods for treatment of Cushing'S disease and hypercortisolism using gefitinib
The invention relates to methods and kits for the treatment of, prevention of, and lowering the chances of developing Cushing's Disease and/or hypercortisolism...
US-9,387,210 Inhibitors of phosphodiesterase type 5A for treating or preventing muscle disease or the symptoms thereof in a...
Disclosed are pharmaceutical compositions and methods for treating or preventing muscle diseases or the symptoms thereof. The compositions typically include and...
US-9,387,209 Histone deacetylases (HDACs) inhibitors
Histone deacetylases inhibitors (HDACIs) and compositions comprising the same are disclosed. Methods of treating diseases and conditions wherein inhibition of...
US-9,387,208 Pharmaceutical formulations of (S)-methyl ...
This invention relates to solid oral pharmaceutical formulations of (S)-methyl (1-((4-(3-(5-chloro-2-fluoro-3-(methylsulfonamido)phenyl)-1-isopropyl-1H-- ...
US-9,387,207 5-HT1A receptor subtype agonist
The present invention relates to a method of treating a patient suffering from a disorder of the central nervous system associated with 5-HT.sub.1A receptor...
US-9,387,206 Therapeutic approaches for treating Alzheimer's disease
The present invention relates to compositions and methods for the treatment of Alzheimer's disease and related disorders. More specifically, the present...
US-9,387,205 Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors
Compounds of the formula Ia***** ##STR00001## in which the substituents have the definitions provided in the specification, are novel, effective PDE4...
US-9,387,204 Fused bicyclic imidazoles
Compounds of formula (I) ##STR00001## a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6 and...
US-9,387,203 Substituted aminoindane- and aminotetralinecarboxylic acids and the use thereof
The present application relates to novel substituted aminoindane- and aminotetralinecarboxylic acids, to processes for preparation thereof, to the use thereof...
US-9,387,202 Pyridone amides and analogs exhibiting anti-cancer and anti-proliferative activities
Compounds useful in the treatment of mammalian cancers and especially human cancers according to Formula I are disclosed. ##STR00001## Pharmaceutical...
US-9,387,201 Methods of providing anti-inflammation support
This disclosure provides products, including pharmaceutical compositions and dietary supplements, which are useful for anti-inflammatory support.
US-9,387,200 Isothiazole-pyridine derivatives as modulators of HIF (hypoxia inducible factor) activity
The present invention relates to novel compounds according to Formula I or II, methods, and compositions capable of decreasing HIF hydroxylase enzyme activity,...
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