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Patent # Description
US-9,393,254 Compositions of A-8R peptide
The present invention provides materials and methods useful to treat various sGC.alpha.1-expressing cancers. Materials include peptides which interfere with...
US-9,393,253 Food composition comprising glucosamine
The present invention relates to an orally ingestible food or pet food composition or cosmetic composition containing glucosamine generated from plant materials...
US-9,393,252 Aromatic carboxylic acids in combination with aromatic hydroxyamides for inactivating non-enveloped viruses
The present invention is directed to antiviral compositions that provide efficacy against non-envelope viruses such as noroviruses. The antiviral compositions...
US-9,393,251 Compositions and methods for treating severe thrombocytopenia related disease
Compositions and methods of treating severe thrombocytopenia and related disease are provided.
US-9,393,250 Phthalocyanine compounds useful as RecA inhibitors and methods of using same
Compounds having the general structural formula (I) wherein X can be any element or compound that can form a coordination complex with phthalocyanine and...
US-9,393,249 Antimicrobial composition
The present invention relates to an improved antimicrobial composition comprising a hydrogen peroxide source and one or more antimicrobial agents. Ideally, the...
US-9,393,248 Aminopyridine derived compounds as LRRK2 inhibitors
The present invention is directed to aminopyridine derived compounds of formula (A) ##STR00001## The compounds are considered useful for the treatment of...
US-9,393,247 Heteroaryl derivatives as alpha7 nAChR modulators
Disclosed is a compound of formula I: ##STR00001## wherein Z, m and R.sup.1-R.sup.6 are as described herein, as a modulator of nicotinic acetylcholine...
US-9,393,246 4,6-disubstituted pyrimidines as kinase inhibitors
The present invention provides 4,6-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods...
US-9,393,245 Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors
The present invention relates to chemical compounds of Formula (I) are as herein defined, pharmaceutical compositions, and methods of use in the treatment of...
US-9,393,244 Increasing parkin activity by administering a deubiquitinating enzyme inhibitor
Provided herein are methods of promoting parkin activity in a subject, comprising: selecting a subject with a disorder associated with decreased Parkin...
US-9,393,243 Topical Ciprofloxacin compositions
Embodiments of the invention provide pharmaceutical compositions of ciprofloxacin formulated for topical application to a body surface and for having at least...
US-9,393,242 Compositions for treatment of ear disorders and methods of use thereof
The present invention relates to compositions and methods useful for the treatment of ear disorders, administered to a treated ear in the form of a foam or a...
US-9,393,241 Compositions for treating CMT and related disorders
The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.
US-9,393,240 Crenolanib for treating FLT3 mutated proliferative disorders
The present invention relates to the use of crenolanib, in a pharmaceutically acceptable salt form for the treatment of FLT3 mutated proliferative disorders...
US-9,393,239 Bicyclic compounds and their use as antibacterial agents and betalactamase inhibitors
A compound of formula (I): ##STR00001## wherein: M is hydrogen or a pharmaceutically acceptable salt-forming cation; Y is OR.sup.1 or NR.sup.2R.sup.3, and...
US-9,393,238 Methods for treating non-hodgkin's lymphoma with ...
Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are...
US-9,393,237 Method of treating thermoregulatory dysfunction with paroxetine
The present invention relates to a method for treating a patient suffering from a thermoregulatory dysfunction, especially hot flashes and flushes associated...
US-9,393,236 Use of 4-cyclopropylmethoxy-N-(3,5-dichloro-1-oxido-4-pyridin-4-yl)-5-(met- hoxy)pyridine-2-carboxamide in the...
The invention relates to the use of 4-cyclopropylmethoxy-N-(3,5-dichloro-1-oxidopyridin-4-yl)-5-(methoxy)pyri- dine-2-carboxamide for the preparation of a...
US-9,393,235 Pyridone amides as modulators of sodium channels
The invention relates to pyridone amide compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: ...
US-9,393,234 Pharmaceutical compositions and methods for treating cancer and biomarkers for drug screening
A pharmaceutical composition comprising sorafenib and GW5074. Said combination therapy inhibits cancer cell growth via c-Raf-PP2A-DAPK signaling transduction...
US-9,393,233 Vector delivery-based microbicides
A new class of anti-microbial agents and methods for preventing or reducing the risk of sexually transmitted infections and/or diseases is provided. Preferably,...
US-9,393,232 Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones
Disclosed are substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compounds, pharmaceutical compositions comprising at least one such 4 substituted...
US-9,393,231 Selenium-containing compound
The invention provides a method of improving an antioxidant effect in a redox pathway that involves selenium in a subject, an in vitro method of inhibiting...
US-9,393,230 Pharmaceutical composition on the basis of phyto-nutrients with increased bioavailability, having anti-tumor...
A pharmaceutical composition for peroral delivery of phyto-nutrients includes at least one phyto-nutrient from the following series: epigallocatechin-3-gallate,...
US-9,393,229 Method for treating abnormal polyglutamine-mediated disease
A method for treating an abnormal polyglutamine-mediated disease is disclosed, wherein indole and an indole-based compound contained in a pharmaceutical...
US-9,393,228 Combination of a slow sodium current blocker and a sinus If current inhibitor, and the pharmaceutical...
The present invention relates to the combination of a selective late sodium current blocker and a selective, specific sinus If current inhibitor, and to the...
US-9,393,227 Nanoscale platinum compounds and methods of use thereof
The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said...
US-9,393,226 Use of osthole for treating focal segmental glomerulosclerosis
The present invention relates to use of osthole for manufacturing a composition for treating focal segmental glomerulosclerosis (FSGS). Particularly, the...
US-9,393,225 Melanoma chemoprevention
Disclosed herein are methods and uses for preventing melanoma, reducing progression of atypical nevi, and inducing cell cycle arrest and/or apoptosis in a...
US-9,393,224 Prophylactic and/or therapeutic agent for cardiovascular complications of diabetes
An object of the present invention is to provide a drug that contains a compound for inhibiting neutral lipid accumulation in cardiovascular tissue or cells and...
US-9,393,223 Hypotensive lipid-containing biodegradable intraocular implants and related methods
Biocompatible intraocular implants include a prostamide component and a biodegradable polymer that is effective in facilitating release of the prostamide...
US-9,393,222 Use of HDAC and/or DNMT inhibitors for treatment of ischemic injury
The present invention provides methods of ameliorating or reducing the extent of ischemic injury, reperfusion injury, and myocardial infarction, by...
US-9,393,221 Methods and compounds for reducing intracellular lipid storage
Compounds and compositions for reducing intracellular lipid accumulation in a cell are described herein. These compounds are useful for the treatment and...
US-9,393,220 Co-crystals of tramadol and NSAIDs
The present invention relates to co-crystals of tramadol and co-crystal formers selected from NSAIDs, processes for preparation of the same and their uses as...
US-9,393,219 Monophenols and benzenediols sensitization of immune system against haptenized melanoma antigens
The metabolization of certain phenols, monophenols or benzenediols into reactive quinone compounds, in particular ortho-quinones and related reactive...
US-9,393,218 Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and...
The subject of this application is the use of film-forming polyurethanes that are used in hair care agents or mixtures of these polyurethanes with other...
US-9,393,217 Self assembled films for protein and drug delivery applications
Provided are systems for controlled release of proteins from decomposable thin films constructed by layer-by-layer deposition. Such films generally comprise...
US-9,393,216 Vaginal matrices: nanofibers for contraception and prevention of HIV infection
Described are drug delivery systems incorporating electrospun fibers that comprise and deliver physicochemically diverse drug compounds. Such fibers provide...
US-9,393,215 Nanoparticles for use in immunogenic compositions
Disclosed herein are sterile-filtered lyophilized nanoparticle compositions which contain at least one biodegradable polymer, at least one surfactant, at least...
US-9,393,214 Carbon encapsulated transition metal oxide nanocomposite, a method for its preparation and its use in li-ion...
A nanocomposite includes carbon-encapsulated transition metal oxide nanoparticles. The carbon-encapsulated transition metal oxide nanoparticles comprise a...
US-9,393,213 Nanocrystals, compositions, and methods that aid particle transport in mucus
Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making...
US-9,393,212 Nanocrystals, compositions, and methods that aid particle transport in mucus
Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making...
US-9,393,211 High drug load buprenorphine microspheres and method of producing same
A sustained release microsphere formulation with a high drug load may be formed by a continuous oil-in-water emulsion process by combining an organic dispersed...
US-9,393,210 Capsules containing high doses of levodopa for pulmonary use
The present invention provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa,...
US-9,393,209 Pill-enveloping material to aid in swallowing pills
The present invention relates to a malleable, palatable pill enveloping material that becomes slippery when in contact with water or saliva making the wrapped...
US-9,393,208 Method for delivering a pharmaceutical composition to patient in need thereof
The present disclosure is directed to a method for delivering a pharmaceutical composition to a patient in need thereof, comprising: administering to said...
US-9,393,207 Pharmaceutical compositions
Pharmaceutical compositions are provided which comprise effective amounts of analgesic to treat a subject, including to reduce or eliminate an adverse effect...
US-9,393,206 Encased tamper resistant controlled release dosage forms
In certain embodiments, the present invention is directed to a solid controlled release dosage form comprising: a core comprising a first portion of an opioid...
US-9,393,205 Gastroretentive tablets
The present invention relates to a gastroretentive tablet comprising pregabalin, at least one swellable polymer, and other pharmaceutically acceptable...
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