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Patent # Description
US-9,394,270 Cytotoxin compounds and methods of isolation
The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these...
US-9,394,269 Process-scale synthesis of urolithins
Disclosed is a method of preparing a urolithin, or an intermediate or analog thereof, having a dibenzo[b,d]pyran-6-one core. The method is especially...
US-9,394,268 (E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-e- n-1-one and analogs thereof, as well...
The present invention relates to millepachine ((E)-1-(5-methoxy-2,2-dimethyl-2H-chromen-8-yl)-3-(4-methoxyphenyl)prop-2- -en-1-one) and its analogs. The present...
US-9,394,267 Heterocyclic modulators of cannabinoid receptors
Heterocyclic compounds which modulate cannabinoid receptors are presented. Pharmaceutical compositions containing these compounds, methods of using these...
US-9,394,266 Solid state forms of cabazitaxel and processes for preparation thereof
The invention relates to solid state forms of Cabazitaxel and processes for preparing the solid state forms. The invention further relates to pharmaceutical...
US-9,394,265 Method for producing alkyldiol monoglycidyl ether
A production method by which an alkyldiol monoglycidyl ether can be efficiently produced without requiring a complex purification step is provided. A method for...
US-9,394,264 Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods...
US-9,394,263 Substituted hetero-azepinones
There are provided compounds of the formula ##STR00001## wherein: V, W, X, Y, Z, R1, R2, R3, R4, R5 and R6 are described herein. The compounds are useful...
US-9,394,262 Method of separating carbon nanotubes
Provided is a method of separating carbon nanotubes, the method comprising: forming first carbon nanotubes having a first functional group, forming a substrate...
US-9,394,261 Aryl amine substituted pyrimidine and quinazoline and their use as anticancer drugs
A series of mono- and di-substituted quinazoline and pyrimidine derivatives based on the skeleton of erlotinib (an EGFR inhibitor) were synthesized and their...
US-9,394,260 Pyrimidinone carboxamide inhibitors of endothelial lipase
The present invention provides compounds of Formula (I): (I) as defined in the specification and compositions comprising any of such novel compounds. These...
US-9,394,259 Auto-rebound switching apparatus and the switching method thereof
An auto-rebound switching apparatus has: a body provided with a water-separating apparatus, an upper cover rotatably arranged on the rear side of the body, a...
US-9,394,258 Arginine methyltransferase inhibitors and uses thereof
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present...
US-9,394,257 PKM2 modulators and methods for their use
Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically...
US-9,394,256 Benzhydrol-pyrazole derivatives having kinase inhibitory activity and uses thereof
The present invention features benzhydrol-pyrazole derivatives and related compounds having kinase inhibitory activity. The compounds of the invention, alone or...
US-9,394,254 Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase
This invention provides a family of compounds that inhibit Class II fructose 1,6-bisphosphate aldolase (FBA), which is implicated in the pathogenic activity of...
US-9,394,253 Kinase protein binding inhibitors
The invention relates to protein binding inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical...
US-9,394,251 Silodosin intermediate and preparation method therefor
Disclosed are a silodosin intermediate and a preparation method thereof. The silodosin intermediate has the structure shown by the formula (A). X is hydrogen or...
US-9,394,250 Substituted pyrrolidines as factor xia inhibitors for the treatment thromboembolic diseases
The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are...
US-9,394,249 IAP binding compounds
IAP binding molecules and compositions including these are disclosed. The IAP binding molecules interact with IAPs (inhibitor of apoptosis proteins) in cells...
US-9,394,248 Process for the manufacture of dihalodiphenylsulfones
A process for the preparation of dihalodiphenylsulfones_such as 4,4'-dichlorodiphenyl sulfone or 4,4'-bis-(4-chlorophenylsulfonyl)biphenyl with high...
US-9,394,247 Method for preparing a sulfonimide compound and salts thereof
The present invention relates to a method for preparing an aqueous sulfonimide compound of the formula (Rf.sup.1--SO.sub.2)(Rf.sup.2--SO.sub.2)NH, wherein...
US-9,394,245 Process for sulfonating halobenzene derivatives with sulfur trioxide
A process for sulfonating at least one halobenzene with sulfur trioxide (SO.sub.3) comprising the following steps: Step 1. manufacturing a gaseous mixture...
US-9,394,244 Ethylenically unsaturated oligomers
Disclosed are functional polyallophanate oligomers comprising ethylenically unsaturated groups and polymer stabilizer groups selected from hindered amine light...
US-9,394,243 (per)fluoropolyether block copolymers
The invention relates to (per)fluoropolyether block copolymers comprising: A) a fluoropolyoxyalkylene segment (chain R.sub.a) comprising one or more units of...
US-9,394,242 Method for preparing dinitrile compound
Disclosed is a method for preparing a dinitrile compound. The method includes reacting an alcohol compound with a nitrile compound having a terminal...
US-9,394,241 Composition and method for making oligo-benzamide compounds
The present invention includes compound compositions and methods of making compounds that include an oligo-benzamide compound having at least two optionally...
US-9,394,240 Method for producing amide derivative
An amide derivative represented by Formula (3), which exhibits excellent efficacy in pest control effect, is produced by allowing a compound represented by the...
US-9,394,239 Biphenyl-3-carboxylic acid modulators of beta-3-adrenoreceptor
The present invention relates to new biphenyl-3-carboxylic acid modulators of beta-3-adrenoceptor activity, pharmaceutical compositions thereof, and methods of...
US-9,394,238 Process for the production of carnitine from .beta.-lactones
The invention relates to a method for the production of L-carnitine, wherein a .beta.-lactone, which is a 4-(halomethyl)oxetane-2-one, is converted into...
US-9,394,237 .beta.-substituted .beta.-amino acids and analogs as chemotherapeutic agents
.beta.-Substituted .beta.-amino acids, .beta.-substituted .beta.-amino acid derivatives, and .beta.-substituted .beta.-amino acid analogs and (bio)isosteres and...
US-9,394,236 .beta.-substituted .gamma.-amino acids and analogs as chemotherapeutic agents
.beta.-Substituted .gamma.-amino acids, .beta.-substituted .gamma.-amino acid derivatives, and .beta.-substituted .gamma.-amino acid analogs and (bio)isosteres...
US-9,394,235 Optical resolution methods for bicyclic compounds using enzymes
An object of the present invention is to efficiently produce an optically active bicyclic compound. The optically active bicyclic compound is efficiently...
US-9,394,234 Lipid formulations
The invention features a cationic lipid of formula I, ##STR00001## an improved lipid formulation comprising a cationic lipid of formula I and corresponding...
US-9,394,233 ROS-activated compounds as selective anti-cancer therapeutics
Provided are compounds according to the following Formula I: ##STR00001## The Formula I compounds are activated in the presence of reactive oxygen species...
US-9,394,232 Cost effective method of producing triarylamine compounds having two alkly alcohols
The present invention provides a simple, cost effective and time saving one step method for synthesizing triarylamines comprising two alkyl alcohol without the...
US-9,394,231 Composition for forming antistatic film and oligomer compound
A composition for forming an antistatic film, includes: an oligomer compound of Formula (1A): ##STR00001## (where R.sub.1 is a hydrogen atom or a group of...
US-9,394,230 Hardeners for epoxy resin coatings
The invention relates to hardeners for epoxy resin containing secondary amino groups having dialkyl amino phenyl groups. The hardeners have a surprisingly low...
US-9,394,229 Method of producing chiral N-substituted allylic amine compounds
The method relates to the field of asymmetric allylic amination and comprises preparing a chiral N-substituted allylic amine compound from the corresponding...
US-9,394,226 3,4-dialkylbiphenyldicarboxylic acid compound, 3,4-dicarboalkoxybiphenyl-3',4'-dicarboxylic acid and...
3,4-Dicarboalkoxybiphenyl-3',4'-dicarboxylic acid represented by the general formula (1): ##STR00001## in which R.sup.11 and R.sup.12 each represents an alkyl...
US-9,394,225 Method for processing fluoric acid
The present invention relates to a method for processing an aqueous solution containing a salt of an organic compound including at least one acid function and...
US-9,394,224 Transesterification process
A transesterification process produces a (meth)acrylate ester product from a mixture comprising an alkyl(meth)acrylate reactant, an alcohol reactant, a...
US-9,394,223 Oxidation process for preparing purified aromatic carboxylic acids
A process including: (a) contacting an aqueous solution including a crude aromatic carboxylic acid with an oxygen source in the presence of an oxidation...
US-9,394,222 Production of methacrylic acid
The invention relates to a process for producing methacrylic acid, comprising: converting a C3-oxygenate into propanoic acid, wherein said C3-oxygenate is a...
US-9,394,221 Method for manufacturing benzenetetracarboxylic acid
By selectively hydrogenating a feedstock containing two or more hydrocarbons selected from the group consisting of tricyclic aromatic hydrocarbons having an...
US-9,394,220 Method for producing bio-methanol at pulp mills
The present invention describes a process and system of producing methanol from methanol condensates. In a preferred embodiment the condensates are biomethanol...
US-9,394,219 Method for producing synthesis gas for methanol production
Method for producing synthesis gas for methanol production The present invention relates to a method for producing synthesis gas from a hydrocarbon containing...
US-9,394,218 Manufacture of methylolalkanes
A multistage tubular reaction system and method for preparing methylol derivatives of an aldehyde includes a tubular reaction system with a plurality of...
US-9,394,217 Staged fluorination process and reactor system
The invention relates to a process to produce 244bb from 1233xf in multiple reaction zones whereby the 1233xf starting material is at least 95% converted to...
US-9,394,216 Complexes of 1-methylcyclopropene with metal coordination polymer networks
Disclosed are adsorption complexes that include 1-methylcyclopropene (1-MCP) and a metal coordination polymer network (MCPN), wherein the MCPN is a porous...
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