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Patent # Description
US-9,404,150 Methods and compositions for universal size-specific PCR
Provided herein are products and processes for the amplification, detection and sequencing of short-stranded nucleic acid in the presence of a high background...
US-9,404,149 Composition, kits and methods for the detection of point mutations and SNPs
The present invention refers to a method for detecting a point mutations of a nucleotide sequence by an improvement of the LAMP (loop amplification mediated...
US-9,404,148 Oligonucleotides and uses thereof
A method for determining the number of tandem repeats in a target polynucleotide, the method comprising (a) providing a sample containing the target...
US-9,404,147 Closed nucleic acid structures
The invention provides compositions and methods for making closed nucleic acid structures in which one or both strands are continuous. The closed nucleic acid...
US-9,404,146 Compositions and methods for nucleic acid sequencing
Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous...
US-9,404,145 Codon-optimized gene for mutated shrimp luciferase and method for use thereof
There has been a demand for a codon-optimized gene for the mutated catalytic domain of Oplophorus luciferase, which is capable of efficiently expressing a...
US-9,404,144 Glucose dehydrogenase
An object of the present invention is to provide a novel glucose dehydrogenase, a method for producing the glucose dehydrogenase, and applications of the...
US-9,404,143 Assays for detecting modified compounds
Provided are methods and compositions which are useful for separating, isolating, detecting, and quantifying compounds of interest which have been modified...
US-9,404,142 Screening methods for identifying Plasmodium proteases inhibitors
The invention relates to the field of parasitology. Methods and peptidic substrate for screening and identifying inhibitors of Plasmodium are described. Also...
US-9,404,141 Method for detecting the presence or absence of a target microbe in a test sample
A method of detecting the presence or absence of a target microbe in a test sample is provided. The method includes the steps of: a) providing a test mixture...
US-9,404,140 Patterned cardiomyocyte culture on microelectrode array
The invention provides a culture of patterned cardiomyocytes, the culture including a support substrate bearing a multielectrode array, a negative surface...
US-9,404,139 Mutated cephalosporin hydroxylase and its application in deacetylcephalosporanic acid synthesis
A mutant hydroxylase with increased activity and greater substrate specificity towards phenylacetyl-7-ADCA derivatives for the production of phenylacetyl-7-HACA...
US-9,404,138 Method for secretory production of protein
A novel technique for improving ability for secretory production of a multimeric protein of a coryneform bacterium is provided, and thereby a method for...
US-9,404,137 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and...
The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a heterocyclic compound. The present...
US-9,404,136 A-xylosidase enhanced conversion of plant biomass into fermentable sugars
The invention relates to increasing the availability of fermentable sugars from plant biomass, such as glucose and xylose. As described herein,...
US-9,404,135 Biomass decomposition apparatus and method thereof, and sugar-solution production system using biomass material
To include a hydrothermal decomposition unit that transports a fed biomass material from one side (a lower side) to the other side (an upper side) by a screw 14...
US-9,404,134 Thermophilic and thermoacidophilic biopolymer degrading genes and enzymes from Alicyclobacillus acidocaldarius...
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are...
US-9,404,133 Polypeptides having peroxygenase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates...
US-9,404,132 Method for producing 1,5-pentamethylenediamine, 1,5-pentamethylenediamine, 1,5-pentamethylene diisocyanate,...
In a method for producing 1,5-pentamethylenediamine, a lysine decarboxylase-expressing microorganism that is subjected to a treatment is used.
US-9,404,131 Process for the preparation of ingenol-3-angelate
The invention relates to methods for preparing ingenol-3-angelate from ingenol or ingenol derivatives.
US-9,404,130 Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway
The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
US-9,404,129 Metabolically engineered cells for the production of resveratrol or an oligomeric or glycosidically-bound...
A recombinant micro-organism producing resveratrol by a pathway in which phenylalanine ammonia lyase (PAL) produces trans-cinnamic acid from phenylalanine,...
US-9,404,128 Processes for the acidic, anaerobic conversion of hydrogen and carbon oxides to oxygenated organic compound
Processes for the bioconversion of syngas to oxygenated organic compound are disclosed that reliably, cost-effectively and efficiently supply sulfur nutrient to...
US-9,404,127 Non-liposomal systems for nucleic acid delivery
The present invention provides novel, stable lipid particles having a non-lamellar structure and comprising one or more active agents or therapeutic agents,...
US-9,404,126 Processes for packaging aggregated oligonucleotides into virus-like particles of RNA bacteriophages
The invention provides processes for the producing compositions comprising (i) a virus-like particle, wherein said virus-like particle is a virus-like particle...
US-9,404,125 Transgenic animal for production of antibodies having minimal CDRs
A transgenic animal is provided. In certain embodiments, the transgenic animal comprises a genome comprising: an immunoglobulin light chain locus comprising: a)...
US-9,404,124 Method of producing induced pluripotent stem cells using inhibitors of P53
Provided is a method of producing an iPS cell, comprising bringing (a) Oct3/4 or a nucleic acid that encodes the same, (b) Klf4 or a nucleic acid that encodes...
US-9,404,123 Nucleic acid assembly, vector, cell, methods and kit thereof
The present disclosure relates to a nucleic acid assembly (NAA), comprising sensor domain and handle domain; an assembly interfaceable motif (AIM) sequence...
US-9,404,122 Endothelial cell production by programming
The invention generally regards methods for providing endothelial cells and precursors of endothelial cells from a variety of cell sources, such as pluripotent...
US-9,404,121 Bacillus thuringiensis gene with lepidopteran activity
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having...
US-9,404,120 Production of plants having improved water-deficit tolerance
The present invention relates to a method for increasing the tolerance of a plant to water deficit, which method comprises the overexpression in said plant of...
US-9,404,119 Cotton fibers having positively charged oligosaccharides
Methods and means are provided for the modification of the reactivity of plant cell walls, particularly as they can be found in natural fibers of fiber...
US-9,404,118 Pichia ciferrii cells and use thereof
The invention relates to genetically modified Pichia ciferrii cells, to the use thereof and to a method of producing sphingoid bases and sphingolipids.
US-9,404,117 Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis
Yeast cells with reduced activity of certain enzymes involved in branched chain amino acid biosynthesis in yeast mitochondria are described. Target enzymes...
US-9,404,116 Method of construction of recombinant organisms using multiple genes co-integration
Provided is a method of simultaneous co-integration of multiple nucleic acid sequences into a microbial organism comprising culturing a microbial organism to be...
US-9,404,115 Coryneform bacterium transformant and process for producing phenol using the same
Provided is a phenol-producing transformant constructed by transferring a gene which encodes an enzyme having chorismate-pyruvate lyase activity and a gene...
US-9,404,114 Antisense modulation of GCGR expression
Provided herein are methods, compounds, and compositions for reducing expression of GCGR mRNA and protein in an animal. Such methods, compounds, and...
US-9,404,113 Antisense modulation of PTP1B expression
Provided herein are methods, compounds, and compositions for reducing expression of PTP1B mRNA and protein in an animal. Such methods, compounds, and...
US-9,404,112 Modified oligonucleotides for telomerase inhibition
Compounds comprising an oligonucleotide moiety covalently linked to a lipid moiety are disclosed. The oligonucleotide moiety comprises a sequence that is...
US-9,404,111 Inhibitors of miRNAs 221 and 222 for anti-tumor activity in multiple myeloma
Inhibitors of miRNAs 221 and 222, and their use as medicaments in the treatment of multiple myeloma. The inhibitors inhibit miRNAs 221 and 222 of the type of...
US-9,404,110 Dermatological, pharmaceutical composition suitable for oligonucleotides
The invention relates to a cosmetic and/or dermatological and/or pharmaceutical composition for the topical use and application of oligonucleotides, in...
US-9,404,109 Compositions and methods for treatment of prostate and other cancers
Therapeutic agents which target heat shock protein (hsp) 27 in vivo are used to provide treatment to individuals, particularly human individuals, suffering from...
US-9,404,108 Micro-RMA inhibitor
The invention provides a microRNA inhibitor that has two or more sequences complementary to the sequence of microRNA to be the target of inhibition, which two...
US-9,404,107 Integration of genes into the chromosome of Saccharopolyspora spinosa
This invention includes a process for the identification and validation of a neutral polynucleotide integration site within the S. spinosa genome. In addition,...
US-9,404,106 Method for preventing, reducing and/or eliminating the fouling of a composite material
A method for preventing, reducing and/or eliminating the fouling of a composite material is provided, the composite material comprising (1) a plurality of...
US-9,404,105 Polyhedral cage-containing mesoporous metal-organic frameworks as platform for biocatalysis, methods of making...
Embodiments of the present disclosure provide compositions including polyhedral mesoporous metal-organic framework including a biomolecule (e.g., enzyme),...
US-9,404,104 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of P38...
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof,...
US-9,404,103 Beta-lactamases with improved properties for therapy
This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (GI tract)...
US-9,404,102 Treatment of disease conditions via administration of DNA repair enzyme
The present invention is directed to compositions and methods of preserving viability of islets of Langerhans for transplantation, and treating various disease...
US-9,404,101 Methods for obtaining positive transformants of a filamentous fungal host cell
The present invention relates to methods for obtaining positive transformants of a filamentous fungal host cell, comprising: transforming a tandem construct...
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