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Polymer, preparation method thereof, composition and film comprising the
Provided is a polymer, a composition and film comprising the polymer, and a preparation method of the polymer. The polymer includes a compound having a...
Aromatic polyethersulfone microparticles having narrow particle diameter
A fine polymer particle production method includes producing an emulsion in a liquid prepared by dissolving and mixing a polymer A and a polymer B in organic...
Polyoxyalkylene-modified vinyl acetal polymer, and composition comprising
There is provided a polyoxyalkylene-modified vinyl acetal polymer which has polyoxyalkylene groups represented by general formula (I) in side chain, in which a...
Aqueous emulsion composition of organic peroxide
An aqueous emulsion composition of organic peroxide, including from 10 to 65% by weight of one or a plurality of organic peroxides, from 2 to 25% by weight of...
Recycle gas cooler systems for gas-phase polymerization processes
Disclosed herein are improvements in recycle gas cooler systems in gas-phase polymerization processes that reduce the tendency for cooler fouling, including a...
Method to produce hyaluronic acid functionalized derivatives and formation
In this invention a two steps procedure is described useful to insert functional groups to the hyaluronic acid (HA), through the formation, in organic solvent,...
Production method for hydrophilic modified polyrotaxane
The present invention aims to provide a method of producing a hydrophilic modified polyrotaxane, which enables production of a hydrophilic modified polyrotaxane...
Method and apparatus for processing fibril cellulose and fibril cellulose
A method for processing fibril cellulose which is in the form of aqueous fibril cellulose gel includes lowering the pH of the aqueous fibril cellulose gel to...
Functionalized graphene substrates
The present invention is generally directed to functionalized graphene substrates, methods of making such substrates and methods of using such substrates. In...
Treatment of food intolerance and food allergy with IgM
A process is provided for inhibiting symptoms of food allergy or food intolerance in a subject that includes the oral adminstration to the subject suffering...
PTK7 modulators and methods of use
PTK modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat hyper-proliferative disorders are provided.
High-affinity monoclonal antibodies to glypican-3 and use thereof
Described herein is the identification of a panel of high affinity monoclonal antibodies that bind GPC3. The disclosed antibodies recognize native GPC3 on the...
Pharmaceutical composition for treatment and/or prevention of pancreatic
This invention relates to a pharmaceutical composition for treatment and/or prevention of pancreatic cancer, comprising as an active ingredient an antibody or a...
Mesothelin domain-specific monoclonal antibodies and use thereof
Described herein is the use of rabbit hybridoma technology, along with a panel of truncated mesothelin domain fragments, to identify anti-mesothelin mAbs that...
Pharmaceutical compositions of antibodies for treatment of diseases caused
by influenza virus
A pharmaceutical composition for prevention or treatment of viral infections including a formulation of full antibodies or fragments of antibodies specific to...
Methods of inhibiting tumor growth by antagonizing IL-6 receptor
The present invention provides methods for inhibiting or attenuating tumor growth in a subject by administering an IL-6 antagonist to the subject. In certain...
Method for making multispecific antibodies having heteromultimeric and
The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin...
Anti-Axl antibodies and uses thereof
The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to...
Polypeptides and polynucleotides, and uses thereof for treatment of immune
related disorders and cancer
This invention relates to LY6G6F, VSIG10, TMEM25 and LSR proteins, which are suitable targets for immunotherapy, treatment of cancer, infectious disorders,...
IL-1 binding proteins
Proteins that bind IL-1.alpha. and IL-1.beta. are described along with their use in compositions and methods for treating, preventing, and diagnosing...
Method for treating psoriasis by administering an anti-IL-12 antibody
Isolated anti-IL-12 antibodies, nucleic acids encoding antibodies or antibody portions, vectors, host cells, and methods of making are useful for production of...
Methods and compositions involving PBEF inhibitors for lung inflammation
conditions and diseases
The present invention concerns methods and compositions involving inhibitors of Pre-B Cell Colony Enhancing Factor (PBEF) for inflammatory conditions and...
Antibody composition-producing cell
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high ...
Antibody to GDF8 and uses thereof
The disclosure provides novel molecules related to growth and differentiation factor 8 (GDF8), in particular epitopes specific to GDF8 and other specific...
Methods for treating patients with complement-associated disorders with
high concentration formulations of...
The present disclosure relates to, inter alia, stable aqueous solutions comprising a high concentration of an antibody that binds to human complement component...
Acceptor framework for CDR grafting
The present invention relates to an antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a particularly...
Modulation of midbody derivatives
The number of midbody derivatives in a cell may be modulated by modulating autophagy induced by NBR1. Exemplary methods include modulating the amount or...
Humanized, anti-N2 antibodies
The present invention encompasses humanized antibodies that specifically bind N2 peptide, methods for the preparation thereof and methods for the use thereof.
CDIM binding proteins and uses thereof
The present disclosure relates to Cell Death Inducing Molecule ("CDIM") binding proteins and pharmaceutical compositions thereof. Particularly, the disclosure...
Antibody binding microbial heparin binding motif to retard or prevent
microbial biofilm formation on implanted...
Methods and reagents for ameliorating biofilm formation on a surface of an indwelling or implanted device in a patient resulting in decreased virulence of...
The present invention relates to fusion proteins comprising fragments from toxin A and/or toxin B of Clostridium difficile, wherein the polypeptide elicits...
Respiratory syncytial virus vaccine
Described is a vaccine against Respiratory Syncytial Virus (RSV). More specifically, described is a recombinant subunit vaccine comprising the ectodomain of the...
Pharmaceutical composition and method of preparing same
An object of the present invention is to provide a pharmaceutical composition comprising an enzyme-treated human serum which is useful for treatment and...
Method of producing recombinant high molecular weight vWF in cell culture
Among other aspects, the present invention relates to cell culture conditions for producing high molecular weight vWF, in particular, highly multimeric WF with...
Polynucleotides encoding BSL2v2c2
The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells....
Repertoire of allo-restricted peptide-specific T cell receptor sequences
and use thereof
The present invention is directed to a kit-of-parts or composition containing nucleic acid sequences coding for high-avidity, allo-restricted TCR, wherein the...
Toll-like receptor-based biosensors
Compositions and methods for detecting Toll-like receptor binding to ligands and test compounds are disclosed herein.
Method for purification of cleaved pro-insulin
The present invention is within the field of biomolecule purification. More closely the invention relates to chromatographic purification of insulin using a...
Glucagon-like peptide-1 derivatives and their pharmaceutical use
The invention relates to protracted Glucagon-Like Peptide-1 (GLP-1) derivatives and therapeutic uses thereof. The GLP-1 derivative of the invention comprises a...
Kidney-specific tumor vaccine directed against kidney tumor antigen G-250
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers...
Rationally designed antibodies
Antibodies or fragments thereof having CDR regions replaced or fused with biologically active peptides are described. Flanking sequences may optionally be...
Embodiments of the present invention provide a fibromodulin (FMOD) peptide (FMOD-P), a composition and a formulation comprising a FMOD-P, option-ally with a...
Methods and compositions for expressing functional class XIV myosin
The invention, in part, includes methods and compounds useful to prepare and functional class XIV myosin. Functional class XIV myosin prepared using methods of...
Cell penetrating peptides to target EIF4E
The present invention provides compounds to disrupt the eIF4E-eIF4G interaction and pharmaceutically acceptable salts of such compounds. Generally, the...
The present invention provides a nucleic acid molecule which encodes a polypeptide consisting of two methionine residues as the first and second N-terminal...
The present invention provides silk proteins, as well as nucleic acids encoding these proteins. The present invention also provides recombinant cells and/or...
Polypeptides having cellulolytic enhancing activity and polynucleotides
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The...
Fusion proteins and combination vaccines comprising Haemophilus influenzae
Protein E and Pilin A
The present invention relates to compositions comprising Haemophilus influenzae Protein E and Pilin A. More particularly, the present application relates to...
Salmonella typhi Ty21a expressing Yersinia pestis F1-V fusion protein and
Described herein is the generation of a plasmid construct for expression of a Yersinia pestis F1-V fusion protein. In the disclosed plasmid, the F1-V fusion...
The application describes electrically conductive nanowires, as well as genetically and/or chemically modified nanowires with modified conductive, adhesive...