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Patent # Description
US-9,421,205 FAK inhibitors
A compound of the formula (I): ##STR00001## where R.sup.1 or R.sup.2 is a cyclic amine group and R.sup.5 is an aromatic group with a carbonyl containing...
US-9,421,204 Oligomer modified diaromatic substituted compounds
The invention relates to (among other things) oligomer modified diaromatic substituted compounds. A compound of the invention, when administered by any of a...
US-9,421,203 Sensitization of cancer cells to DNA damage by inhibiting kinases essential for DNA damage checkpoint control
The invention provides methods for overriding cell cycle arrest in a tumor cell, which comprise inducing DNA damage in the cell, and contacting the cell with an...
US-9,421,202 Procaspase combination therapy for glioblastoma
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods...
US-9,421,201 Treating pain in patients with hepatic impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
US-9,421,200 Treating pain in patients with hepatic impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
US-9,421,199 Ophthalmic composition
Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of an ophthalmic agent for treatment...
US-9,421,198 Composition comprising hyaluronic acid and mepivacaine
Compositions and methods for the surface appearance of the skin a subject are provided. An injectable composition comprising at least hyaluronic acid or a salt...
US-9,421,197 Methods of generating hyper INOS expressing cells and uses thereof
A method of generating a hyper iNOS expressing cell includes administering to a myeloid derived cell an amount of a PPAR.gamma. agonist and an IL-6/STAT3...
US-9,421,196 Amides as modulators of sodium channels
The invention relates to amide compounds of formula I and I' or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: ...
US-9,421,195 Methods of treating hepatic encephalopathy
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic...
US-9,421,194 Lung targeting dual drug delivery system
The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and...
US-9,421,193 Benzothiazole derivatives and a use thereof for the treatment of cancer
Provided are a compound represented by Formula I, a pharmaceutically acceptable salt thereof, or a solvate thereof; and a pharmaceutical composition for cancer...
US-9,421,192 Hepatitis C virus inhibitors
The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical...
US-9,421,191 Ready to use ketorolac formulations
Disclosed in certain embodiments is a pharmaceutical composition for parenteral administration comprising: an aqueous solution comprising ketorolac or a...
US-9,421,190 Compositions comprising amino acids for prevention and/or treatment of renal disorders
Composition comprising leucine, isoleucine, valine, threonine and lysine for use in prophylactic and/or therapeutic treatment of renal disorders in a subject,...
US-9,421,189 Method of preparing a muscadine pomace extract
Disclosed herein is a method of producing a muscadine pomace extract. The method can include combining a bronze muscadine pomace extract with a purple muscadine...
US-9,421,188 Combination product comprising phentermine and topiramate, and preparation method thereof
The present invention provides a combination product, which comprises immediate release pellet of phentermine and sustained-release pellet of topiramate,...
US-9,421,187 Phytocannabinoids for use in the treatment of intestinal inflammatory diseases
The present invention relates to one or more of the phytocannabinoids tetrahydrocannabivarin (THCV); cannabigerol (CBG); cannabichromene (CBC); and...
US-9,421,186 Method for improving therapy for autoimmune diseases such as rheumatoid arthritis
In the present invention, a method using a combination of iguratimod or a salt thereof and one or more immunosuppressants is useful as a method for the...
US-9,421,185 Diagnosis and treatment methods for entry of gastrointestinal contents into respiratory tract
A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The...
US-9,421,184 Diethyl-[6-(4-hydroxycarbamoyl-phenyl-carbamoyloxy-methyl)-naphthalen-2-yl- -methyl]-ammonium chloride for use...
The present invention relates to a method for treating muscular dystrophy which comprises administering ...
US-9,421,183 Compositions comprising sulforaphane or a sulforaphane precursor and a mushroom extract or powder
The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme...
US-9,421,182 Cocrystals of dimethyl fumarate
Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.
US-9,421,181 Antihypoxic pharmaceutical composition and application thereof
The present invention discloses an antihypoxic pharmaceutical composition and application thereof. The pharmaceutical composition contains vinpocetine and...
US-9,421,180 Antioxidant compositions for treatment of inflammation or oxidative damage
One embodiment of the invention is directed to a method of preventing, reducing, or eliminating at least one negative effect of oxidative damage, such as an...
US-9,421,179 Acamprosate formulations, methods of using the same, and combinations comprising the same
Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in...
US-9,421,178 Acamprosate formulations, methods of using the same, and combinations comprising the same
Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in...
US-9,421,177 Imidamide sphingosine kinase inhibitors
Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can...
US-9,421,176 Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic...
This disclosure relates to methods of increasing dextromethorphan plasma levels comprising co-administering hydroxybupropion, or a prodrug thereof, and...
US-9,421,175 Prevention of retinopathy by inhibition of the visual cycle
The invention relates to compounds capable of inhibiting the visual cycle and/or dark adaptation and their use for treatment and prevention of non-degenerative...
US-9,421,174 Transdermal therapeutic system with high rate of utilization of active substance and dosing accuracy
A transdermal therapeutic system for administering at least one active pharmaceutical ingredient, including a polymer layer which is remote from the skin and is...
US-9,421,173 Nano delivery systems for siRNA
The present invention makes use of a unique methodology of double nano-encapsulation for protecting and controlling the release of active agents, either...
US-9,421,172 Lipidated glycoprotein particles and methods of use
Lipidated micro- or macroparticles are prepared by covalently linking a glycoprotein, typically collagen, with at least one lipid. An amino group in the...
US-9,421,171 Coated solid dosage forms
The invention is associated with ingestible film coated solid dosage forms comprising natural honey in the coating applied to such forms. The natural honey of...
US-9,421,170 Multiple unit dosage form having a therapeutic agent in combination with a nutritional supplement
Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a...
US-9,421,169 Oral dosage forms for delivery of therapeutic agents
Oral dosage forms for the delivery of therapeutic agents include mechanical fasteners for engaging tissue of the gastrointestinal tract.
US-9,421,168 Compositions for achieving a therapeutic effect in an anatomical structure
Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order...
US-9,421,167 Preparation of microvesicle-siRNA complexes and use thereof in AIDS treatment
The present invention provides drugs for treating AIDS, which comprises microvesicles carrying anti-HIV specific siRNA. The present invention also provides a...
US-9,421,166 Pulmonary delivery of aminoglycoside
The present invention is directed to the administration of aminoglycosides. In particular, the present invention is directed to compositions and methods for the...
US-9,421,165 Oral controlled release pharmaceutical compositions of bepotastine
The present invention relates to oral controlled release pharmaceutical compositions comprising Bepotastine. The oral controlled release pharmaceutical...
US-9,421,164 Stimuli responsive adhesive gel for removal of foreign particles from soft tissue
The present inventions are directed to novel aqueous compositions comprising a copolymer having water-soluble units and pendant catechols, said composition...
US-9,421,163 Topical compositions comprising polyunsaturated fatty acids
The present disclosure provides topical compositions comprising a polyunsaturated fatty acid (PUFA) derivative of formula (I): ##STR00001## or a salt thereof.
US-9,421,162 Methods of using polymeric compositions containing IR-emitting absorbing additives
Polymeric compositions containing additives having properties of emission and/or absorption of radiation in the long infrared region, and articles shaped...
US-9,421,161 Herbal composition and a method of making thereof
A topical composition is prepared using macerated leaves of St. Andrew's Cross (hypericum hypericoides). An aqueous extract of the leaves is mixed with ethanol...
US-9,421,160 Method for chemical smoothing of human hairs
A method for reshaping, in particular for straightening, keratin-containing fibers, in particular human hair, includes (i) applying a pretreatment agent...
US-9,421,159 Protein-acrylate copolymer and hair conditioning product comprising said polymer
A protein-acrylate copolymer contains at least one nitrogen containing acrylic monomer. The nitrogen containing acrylic monomer preferably contains a tertiary...
US-9,421,158 Agent and method for the temporary deformation of keratin fibres
Cosmetic preparations based on hydrophobically modified (meth)acrylic acid copolymers and hydrophobically modified polysaccharides are described, together with...
US-9,421,157 Use of C-glycoside derivatives as pro-desquamating active agents
A cosmetic use of at least one C-glycoside derivative in a composition comprising a physiologically acceptable medium, as a cosmetic agent for promoting the...
US-9,421,156 Silicone elastomer particle and an aqueous dispersion comprising the same
One of the purposes of the present invention is to provide a silicone elastomer particle and an aqueous dispersion of the silicone elastomer particles, which...
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