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Patent # Description
US-9,427,498 Syringe treated with transdermal venous access locking solutions and method of treating the syringe
Microbial growth inhibiting solutions and methods of employing the microbial growth inhibiting solutions in flushing and coating medical devices are disclosed....
US-9,427,497 Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
A structure of, and a method of producing, a biocompatible structure for bone and tissue regeneration are disclosed. The method includes dissolving a...
US-9,427,496 Method for creating an internal transport system within tissue scaffolds using computer-aided tissue engineering
An artificial tissue including an internal mass transport network having a plurality of channels, wherein the channels are designed to substantially mimic...
US-9,427,495 Multi-phased, biodegradable and oesteointegrative composite scaffold for biological fixation of musculoskeletal...
Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of...
US-9,427,494 Fibre-based surgical implant and method of manufacture
A fiber-based surgical implant stabilized against fraying, includes a thermally crimped flat-knitted fabric of a biocompatible, optionally biodegradable,...
US-9,427,493 Shape memory polymer intraocular lenses
A shape memory polymer (SMP) intraocular lens may have a refractive index above 1.45, a Tg between 10.degree. C. and 60.degree. C., inclusive, de minimis or an...
US-9,427,492 Composition containing injectable self-hardened apatite cement
A method of producing an injectable calcium phosphate paste by a process in which calcium phosphate precursors are mixed with the setting fluids to form a...
US-9,427,491 Bone pastes comprising biofunctionalized calcium phosphate cements with enhanced cell functions for bone repair
The invention provides injectable, biofunctional agent-containing calcium phosphate cement bone pastes for bone tissue engineering, and methods of making and...
US-9,427,490 Gelatin sponge comprising an active ingredient, its preparation and use
The present invention is directed to a method for manufacturing a cross-linked gelatin sponge having a surface by providing a cross-linked gelatin sponge,...
US-9,427,489 Spray foam splint
Orthopedic splinting materials and methods for stabilizing an injured limb or extremity of a human or animal comprising applying a foam to the limb or extremity...
US-9,427,488 Disinfection system of contact lens
A disinfection system of a contact lens comprising immersing the contact lens in a disinfecting solution containing hydrogen peroxide in a concentration of 1 to...
US-9,427,487 Attachable fabric scent diffuser
A fabric scent diffuser that can be easily and strongly attached to a pet collar which is then worn by a pet with the portable scent diffuser providing an...
US-9,427,486 Filter cartridge for an air purifier
Provided is a filter cartridge for an air purifier, comprising a structure ensuring the retention of a filter medium, the filter medium comprising a standard...
US-9,427,485 Hydrogen peroxide sterilization method
A metering unit is provided for metering hydrogen peroxide into an evacuated vessel, for controlling the concentration of hydrogen peroxide in the vessel. The...
US-9,427,484 Cloth and fabric sterilizer utilizing upright holding tub
A household sterilizer for disinfecting fabric material that has become soiled. The unit involves an upright tub containing an electric heating element at its...
US-9,427,483 Radioisotope trithiol complexes
The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of...
US-9,427,482 Agents for clearing biomolecules from circulation
Described is a method, and a combination of agents for used therein, by which an agent administered to a subject can be rapidly cleared from circulation. This...
US-9,427,481 Fluorescent imaging agents
Provided is a family of intramolecularly quenched imaging agents for use in both in vivo and in vitro imaging that contain at least one enzymatically cleavable...
US-9,427,480 Duocarmycin ADCs for use in treatment of endometrial cancer
The present invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for use in the treatment of human solid tumors expressing HER2, wherein...
US-9,427,479 Tubulysin derivatives
Novel tubulysin derivatives which may be useful as cytotoxic agents to provide therapeutic benefits in the treatment of various types of cancers, alone, as drug...
US-9,427,478 Enzymatic conjugation of polypeptides
The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking...
US-9,427,477 Cancer treatments
This document provides methods and materials related to treating cancer (e.g., skin cancer). For example, methods and materials relating to the use of a...
US-9,427,476 Multivalent meningococcal conjugates and methods for preparing conjugates
Disclosed herein are meningococcal immunogenic conjugates which can elicit immune responses against meningococcal polysaccharides (PS) from groups A, C, W-135,...
US-9,427,475 Glucose-responsive insulin conjugates
Insulin conjugates comprising an insulin molecule covalently attached to at least one bi-dentate linker having two arms, each arm independently attached to a...
US-9,427,474 Conjugates of a polymer, a bisphosphonate and an anti-angiogenesis agent and uses thereof in the treatment and...
Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing...
US-9,427,473 Aqueous ophthalmic composition
The present invention relates to an aqueous ophthalmic composition comprising (A) polyoxyethylene castor oil, (B) polyethylene glycol monostearate, and (C) at...
US-9,427,472 Controlled release compositions for modulating free-radical induced damage and methods of use thereof
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations...
US-9,427,471 Method and improved pharmaceutical composition for enhancing transdermal delivery of PDE-5 inhibitor
The present disclosure relates to the use of an agent that enhances transdermal delivery of a PDE-5 inhibitor. More particularly, the present disclosure...
US-9,427,470 Hyaluronic acid stabilizer
An embodiment of the present disclosure provides a composition that includes hyaluronic acid, or its salt or derivative thereof, zinc citrate and an additive...
US-9,427,469 Soluble physiological chitosan formulations combined with platelet-rich plasma (PRP) for tissue repair
The present disclosure relates to an activated polymer composition for use in repairing tissue of a patient comprising platelet-rich plasma (PRP), a chitosan...
US-9,427,468 Compositions and methods for diagnosing and treating community-acquired methicillin-resistant Staphylococcus aureus
The present invention includes compositions and methods for diagnosing and treating CA-MRSA infections in patients. The methods are based on the finding that...
US-9,427,467 Hair removal with metal nanoparticles in surfactant containing solutions
Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic...
US-9,427,466 Nanoparticle-assisted ultrasound for breast cancer therapy
Methods for reducing the growth of breast cancer cells in a subject by exposing the cells to nanoparticles, and irradiating with a focused, low to medium power...
US-9,427,465 Selective resonance of chemical structures
A method of screening for the presence of a composition in a medium includes selecting a score record for a score that affects the composition, and applying...
US-9,427,464 Anti-human TROP-2 antibody having an antitumor activity in vivo
The present invention provides: an antibody which specifically reacts with hTROP-2 and has anti-tumor activity in vivo (particularly, a humanized antibody); a...
US-9,427,463 Combination therapy with CD4 lymphocyte depletion and mTOR inhibitors
The invention provides methods for treating a malignant neoplastic cell proliferative disorder or disease, comprising administering to a subject in need thereof...
US-9,427,462 Reagents and methods for detecting influenza virus proteins
Two universally conserved sequences from influenza type A neuraminidases were identified by large scale sequence analysis then chemically modified and...
US-9,427,461 TOPK peptides and vaccines including the same
The present invention provides isolated epitope peptides derived from TOPK and immunogenic fragments thereof have an ability to induce cytotoxic T lymphocytes...
US-9,427,460 Use of miR-494 to modulate TRAIL-induced apoptosis through BIM down-regulation
Methods and compositions for inhibiting tumorigenicity both in vitro and in vivo in a subject in need thereof, comprising administering an effective amount of...
US-9,427,459 Synergistic pharmaceutical composition for topical applications
A synergistic pharmaceutical composition for the preparation of topical formulations for use in prophylaxis and treatment of wounds, burn wounds, skin grafts,...
US-9,427,458 Methods for inhibiting cancer cell proliferation
The present invention concerns methods of treating cancer and methods of inhibiting cancer cell proliferation, particularly methods of treating breast cancer,...
US-9,427,457 Wnt signaling inhibitor comprising insulin-like growth factor-binding protein
Provided is a novel soluble factor that modulates morphogenesis and cell proliferation, such as cardiac development and/or cardiomyocyte differentiation....
US-9,427,456 Peptide therapy for increasing platelet levels
The present invention is directed to novel therapeutic uses of T-140 analog peptides and compositions comprising same. Specifically, the invention relates to...
US-9,427,455 Use of the pat nanopeptide in the treatment of autoimmune diseases
The invention refers to the use of the PAT nonapeptide which is a thymuline analog in the treatment of autoimmune diseases, in particular of rheumatoid...
US-9,427,454 Method of making liquid olive leaf extract
A method of making liquid olive leaf extract that includes the mixing ground olive leaf, water, and an acid in a container. Once mixed heating the mixture a...
US-9,427,453 Irvingia gabonensis to treat and prevent metabolic syndrome and reduce total cholesterol, LDL cholesterol,...
In one embodiment, a method is provided for lowering C-reactive protein levels in a mammal. The method comprises administering a composition containing an...
US-9,427,452 Method for preparing fermentation broth of fruits and vegetables
A method for preparing fermentation broth of fruits and vegetables includes steps of mixing fruits, vegetables, bacteria liquid of Lactobacillus acidophilus,...
US-9,427,450 Therapeutic immune modulation by stem cell secreted exosomes
Disclosed are methods, compositions of matter, and protocols useful for the induction of a therapeutic immune modulatory response through administration of...
US-9,427,449 Binding of galectin-3 by low molecular weight pectin
Administration of low molecular weight (10,000-20,000 Daltons, or lower) pectins, particularly modified citrus pectins (MCP), like PectaSol-C reduces...
US-9,427,448 Methods of treating, reducing the incidence of, and/or preventing ischemic events
Methods of treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing percutaneous coronary intervention (PCI), comprising...
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