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Patent # Description
US-9,434,965 Production method for organic acid using CoA-transferase
The present invention relates to a method of producing organic acids, comprising biochemical synthesis of organic acid-CoA using acetyl-CoA as a substrate and...
US-9,434,964 Microorganisms for the production of 1,4-butanediol and related methods
The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid...
US-9,434,963 Process for butanol production
This invention comprises a process for the bioconversion of a fermentable carbon source to n-butanol by a microorganism, wherein the microorganism is deficient...
US-9,434,962 Integrated process for producing biofuels
Disclosed is an integrated process comprising first and second biotechnical processes. The first process produces biofuel and/or starting material for biofuel...
US-9,434,961 Continuous process for the production of ethanol from lignocellulosic biomass
A continuous process for the recovery of ethanol from hemicellulose and cellulose from lignocellulosic biomass. Yield of fermentable sugars can be maximized by...
US-9,434,960 Methods for making and using modified oocytes
The present invention provides modified oocytes having a nuclear genome derived from a first oocyte and cytoplasm derived from a second oocyte from a different...
US-9,434,959 Virus-like particles for treatment of viral infections
The invention provides virus-like particles for treatment of viral infections based on the virus causing the infection. The virus-like particles comprise the...
US-9,434,958 Complex disease resistant monocot having optimized agronomic characteristics
The present inventors isolated many promoters having various expression characteristics from monocots, connected the OsWRKY45 gene downstream of these...
US-9,434,957 Methods of improving drought tolerance and seed production in rice
The invention provides for compositions and methods for producing plants that have higher yield in drought conditions by manipulating the G-proteins such as the...
US-9,434,956 Transgenic plants with enhanced growth characteristics
The invention relates to transgenic plants exhibiting dramatically enhanced growth rates, greater seed and fruit/pod yields, earlier and more productive...
US-9,434,955 Proteins relating to grain shape and leaf shape of rice, coding genes and uses thereof
The present invention provides a protein OsXCL relating to grain shape and leaf shape of rice, its derived proteins and their coding genes. Transgenic rices...
US-9,434,954 Plants with altered levels of vegetative starch
Vectors for altering the expression of one or more starch regulation enzymes are provided. Methods of transformation of plant tissues to express elements...
US-9,434,953 Methods and compositions for modified ethanol inducible promoter systems
The present invention provides nucleic acid molecules comprising one or more nucleotide sequences selected from the group consisting of the nucleotide sequence...
US-9,434,952 Selectable marker gene and methods of use thereof in transplastomic plants
Compositions and method for the generation of transplastomic plants are provided.
US-9,434,951 Compositions and methods for decreasing leukocyte extravasation and vessel fluid leakage
Provided herein are methods of decreasing leukocyte extravasation from a lymph or blood vessel into a tissue in a mammal, methods of decreasing fluid leakage...
US-9,434,950 Double-stranded and single-stranded RNA molecules with 5' Triphosphates and their use for inducing interferon
Double-stranded and single-stranded RNA molecules, and their use in methods for inducing interferon are provided. The interferon induction provides anti-viral...
US-9,434,949 Uses of the human ZFX gene and drugs associated with same
The present invention discloses uses of the human ZFX gene and drugs associated therewith. Also disclosed are uses of the human ZFX gene in tumor treatment,...
US-9,434,948 Multiple exon skipping compositions for DMD
Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof...
US-9,434,947 Modulation of KCNH2 isoform expression by oligonucleotides as a therapeutic approach for long QT syndrome
Oligonucleotides with activity in preventing poly(A) adenylation at intron 9 of the KCNH2 gene, as well as pharmaceutical compositions comprising the...
US-9,434,946 Combination therapy for treating hearing and balance disorders
The present application relates to combinations of inhibitors directed at down-regulation of genes associated with hearing loss including HES1, HES5, HEY2,...
US-9,434,945 Use of miR-23a-3p and/or miR-27a-3p mimics as therapeutic agents for inhibition of neuronal apoptosis following...
The present invention relates to a method for treating a brain injury due to a traumatic event, disease or ischemic attack in a mammal subject, wherein the...
US-9,434,944 Modulators of miR-323-3p for the prevention or treatment of rheumatoid arthritis
A miR-323-3p inhibitor is provided for the prevention or therapy of rheumatoid arthritis, comprising a sequence capable of forming a hybrid to miR-323-3p as an...
US-9,434,943 RNA interference for the treatment of gain-of-function disorders
The present invention relates to the discovery of an effective treatment for a variety of gain-of-function diseases, in particular, Huntington's disease (HD)....
US-9,434,942 Small interfering RNAS with target-specific seed sequences
Disclosed are methods for design and synthesis of siRNA libraries, siRNA libraries produced thereby, siRNA molecules, and uses thereof.
US-9,434,941 Method for producing circular DNA formed from single-molecule DNA
There is provided a method for producing a circular DNA which consists of a circular DNA formed from a single-molecule DNA and which does not comprise circular...
US-9,434,940 Methods for universal target capture
The invention generally relates to methods for universal target capture.
US-9,434,939 Instrument for cassette for sample preparation
A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel...
US-9,434,938 Systems and methods for enhanced SCODA
Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules...
US-9,434,937 Rapid cell purification systems
Methods and systems for purifying cells and/or viruses are provided. The sample is added to a well disposed in a medium. A potential is applied across the...
US-9,434,936 Method for removing cells
A method for separating cells which includes: adhering cells to the surface of a cell culture substrate containing a photo-acid generator that generates an...
US-9,434,935 Modified caspase polypeptides and uses thereof
The technology relates in part to compositions comprising modified Caspase-9 polypeptides, compositions comprising nucleic acids coding for modified Caspase-9...
US-9,434,934 Heat stable keratinase and use thereof
A fusion gene encoding M. taiwanensis WR-220 keratinase is disclosed. The fusion comprises: (a) a first DNA sequence encoding a protein secretion signal...
US-9,434,933 Crystal
The present invention relates to a crystal. In particular the present invention relates to a crystal of the N-domain of ACE protein. The present invention also...
US-9,434,932 Alpha-amylase variants
The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid...
US-9,434,931 Rationally-designed single-chain meganucleases with non-palindromic recognition sequences
Disclosed are rationally-designed, non-naturally-occurring meganucleases in which a pair of enzyme subunits having specificity for different recognition...
US-9,434,930 Method of producing dicer
The present disclosure provides a method for producing a Dicer polypeptide in a prokaryotic host cell. The present disclosure further provides a purified Dicer...
US-9,434,929 Esterases useful in the treatment of cellulosic and lignocellulosic material
The present invention discloses novel polypeptides and enzyme preparations containing them, which improve the efficiency of cellulose and lignocellulose...
US-9,434,928 Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides
The present invention relates to recombinant adeno-associated virus (rAAV) delivery of an alpha-sarcoglycan gene. The invention provides rAAV products and...
US-9,434,927 Method for manufacturing cell culture substrate
A method for manufacturing a cell culture substrate obtained by forming a coating layer of a polymer on the surface of a substrate, wherein the polymer is...
US-9,434,926 Graphene hydrogel and methods of using the same
Provided herein are hydrogel compositions containing graphene, chitosan, a polyethylene (glycol) diacrylate (PEGDA). The hydrogel can optionally contain an...
US-9,434,925 Genetically modified mesenchymal stem cell that express an exogenous cytotoxic protein
This invention provides a method for treating a subject afflicted with a tumor using genetically modified mesenchymal stem cells, wherein each genetically...
US-9,434,924 Cell culture method and cell culture kit
Provided is a means suitable for mass culture of adherent cells and which allows easy and safe collection of the cultured adherent cells. A cell culture kit has...
US-9,434,923 Preparation of parental cell bank from foetal tissue
The present invention relates to methods of in vitro preparation of a parental cell bank (PCB) from foetal tissue consisting of foetal epiphyseal tissue, foetal...
US-9,434,922 Feeder-free method for culture of bovine and porcine spermatogonial stem cells
The present invention relates to the production and culture of undifferentiated spermatogonial stem cells that can be maintained long term and are feeder free....
US-9,434,921 Methods for mitochondrial DNA replacement in oocytes
Methods are provided for producing a primate oocyte in vitro. The methods include removing nuclear DNA from a recipient primate oocyte from a first primate in a...
US-9,434,920 Defined media for expansion and maintenance of pluripotent stem cells
The present invention provides methods to promote the proliferation of undifferentiated pluripotent stem cells in defined media. Specifically, the invention...
US-9,434,919 Fungal proteases
The present invention provides fungal proteases and improved fungal strains that are deficient in protease production.
US-9,434,918 System for aging beer
An insulated beer fridge stores and ages corked craft beer in a vertical orientation for a period of several months to years without degrading the cork stopper...
US-9,434,917 Wort boiling method and apparatus
An energy-saving method and apparatus for boiling wort in a beer brewing process is easily implemented and managed. The wort (W) to be boiled is supplied to a...
US-9,434,916 Detergent products, methods and manufacture
A water-soluble pouch suitable for use in machine dishwashing and which comprises a plurality of compartments in generally superposed or superposable...
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