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Patent # Description
US-9,434,713 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases
The present invention relates to novel 5,6-disubstituted oxindole derivatives and pharmaceutically acceptable salts thereof, and pharmaceutical compositions...
US-9,434,712 Processes for the preparation of pesticidal compounds
The present application provides processes for making pesticidal compounds and compounds useful both as pesticides and in the making of pesticidal compounds.
US-9,434,711 Sulfonamides as TRPM8 modulators
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are...
US-9,434,710 Method for converting aloeresin A to aloesin
The invention provides a process for hydrolytically converting aloeresin A to aloesin by the following reaction: The amount of aloesin available for extraction...
US-9,434,709 Production of adipic acid and derivatives from carbohydrate-containing materials
The present invention generally relates to processes for the chemocatalytic conversion of a glucose source to an adipic acid product. The present invention...
US-9,434,708 Process for carrying out a reaction involving a liquid reaction mixture
In a process for carrying out a reaction, a liquid reaction mixture is contacted with a catalyst that includes silica and/or a silicate, in which process a...
US-9,434,707 PDE10 inhibitors and related compositions and methods
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety,...
US-9,434,706 1,4-butanediol-containing composition
A 1,4-butanediol (1,4BG)-containing composition having high thermal stability, and having a concentration of 1,4-butanediol of 99.00% by weight or more and not...
US-9,434,705 L-setastine hydrochloride and preparation method thereof
The present invention relates to the field of medicine, and disclosed are an L-setastine hydrochloride and a preparation method therefor. The compound of the...
US-9,434,704 Compositions and methods for the treatment of neurological degenerative disorders
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers,...
US-9,434,703 Viloxazine compositions
Provided here are methods of manufacture of viloxazine and its various salts, as well as viloxazine-related compounds, such as novel intermediate reaction...
US-9,434,702 Method for preparing linezolid intermediate
Disclosed is a new method for preparing a methyl substitute of a linezolid intermediate, (S)-2-(3-(3-fluoro-4-morpholinophenyl)-2-oxo-5-oxazoline) (I), wherein ...
US-9,434,701 Aminoquinoxaline derivatives for treatment of neurodegenerative diseases
The present invention relates to compounds of formula (I) below: for which: --X represents a hydrogen atom, a halogen atom, a group NO.sub.2 or NH.sub.2,...
US-9,434,700 Inhibitors of the fibroblast growth factor receptor
Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
US-9,434,699 Iodine(III)-mediated radiofluorination
A process for fluorination of aromatic compounds employing iodonium ylides and applicable to radiofluorination using .sup.18F is described. Processes,...
US-9,434,698 Process for preparing antiviral compounds
This disclosure is directed to: (a) processes for preparing compounds and salts thereof that, inter alia, are useful for inhibiting hepatitis C virus (HCV); (b)...
US-9,434,697 Pyrimidine FGFR4 inhibitors
Provided herein are compounds of Formula I useful as FGFR4 inhibitors, as well as methods of use of the same.
US-9,434,696 Process for the preparation of enantiomeric forms of 2,3-diaminopropionic acid derivatives
The disclosure relates to a process for the preparation of the enantiomeric forms of 2,3-diaminopropionic acid derivatives of formula I, ##STR00001## wherein...
US-9,434,695 Nitrogenous heterocyclic derivatives and their application in drugs
The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses...
US-9,434,694 Method for preparation of medetomidine with chloroacetone
The invention discloses a method for the preparation of medetomidine starting from 1-bromo 2,3-dimethylbenzene and chloroacetone.
US-9,434,693 Substituted pyrazoles as N-type calcium channel blockers
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are...
US-9,434,692 Pyrazole derivatives as modulators of the 5-HT.sub.2A serotonin receptor useful for the treatment of disorders...
Pyrazole derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the serotonin 5HT.sub.2A receptor. Formula (Ia)....
US-9,434,691 Process for the preparation of a PDE4 inhibitor
The present invention relates to a process for the preparation of compounds endowed with phosphodiesterase (PDE4) inhibitory activity having formula (I). The...
US-9,434,690 Substituted oxopyridine derivatives and use thereof in the treatment of cardiovascular disorders
The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the...
US-9,434,689 Processes for the preparation of isoindole compounds and isotopologues thereof
Processes for the preparation of certain isoindole compounds, and isotopologues thereof, are provided. In some embodiments, the processes comprise catalytic...
US-9,434,688 Indole derivatives as selective androgen receptor modulators (SARMS)
The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and...
US-9,434,687 Detection of synthetic cannabinoids
The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies...
US-9,434,686 Deacetylase inhibitors and uses thereof
The present invention provides novel compounds of formula (I) and pharmaceutical compositions thereof. The inventive compounds are useful as deacetylase...
US-9,434,685 Preparation and thermal curing of single-ring bis(cyanate) ester monomers
A class of modified single-ring cyanate esters which have shown the ability to tailor and control the glass-transition (Tg) of the cured resins as well as the...
US-9,434,684 Oxime-substituted amide compound and pest control agent
To provide a novel pesticide, especially a fungicide and a nematocide. An oxime-substituted amide compound represented by the formula (I) or its salt, and a...
US-9,434,683 Titanium-silicalite molecular sieve, method for preparing the same and method for preparing cyclohexanone oxime...
The present invention provides a titanium-silicalite molecular sieve and a method for preparing the same. The method includes the steps of preparing a mixture...
US-9,434,682 Reactive mesogen compound having superior thermostability and high birefringence and method of preparing the same
Disclosed are a novel reactive mesogen compound having superior thermostability, high birefringence and a simple preparation process while possessing unique...
US-9,434,681 Macromolecules for treating atherosclerosis
The invention includes compounds of the formula I and formula II and salts thereof, as well as methods for using the compounds of formula I and formula II for...
US-9,434,680 Methods for synthesizing and purifying aminoalkyl tetracycline compounds
Methods for the synthesis and purification of 9-amino alkyl tetracycline compounds are described.
US-9,434,679 Allyl-bearing fluorinated ionomers
The present invention provides a fluorinated ionomer [polymer (I)] comprising recurring units derived from at least the following monomers: (i) 5 to 50% by...
US-9,434,678 Process for preparing alkyl pyroglutamic acids
This disclosure relates to methods for limiting the undesired reverse Mannich reaction during the hydrogenation reduction of one or more nitro functional groups...
US-9,434,677 Natural and synthetic compounds for treating cancer and other diseases
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast,...
US-9,434,676 Flavor and fragrance formulation (VI)
The present invention relates to the use of specific organic compounds of formula (I) as flavor and fragrance material. Furthermore the invention relates to a...
US-9,434,675 Method for producing isononanoic acid esters, starting from 2-ethyl hexanol
A Process for preparing carboxylic esters of a mixture of structurally branched C9 monocarboxylic acids proceeding from 2-ethylhexanol is characterized in that ...
US-9,434,674 Latent heat storage using renewable phase change materials
A method of producing a diol diester, which includes reacting a fatty acid alkyl ester having 6 to 30 carbon atoms, an .alpha.,.omega.-alkanediol having n...
US-9,434,673 Process for preparing vinylidenecarboxylic acid (ester)s by reaction of formaldehyde with alkylcarboxylic acid...
Process for preparing a vinylidenecarboxylic acid or ester thereof, wherein a reaction gas comprising gaseous formaldehyde, molecular oxygen and an...
US-9,434,672 Method for producing isononanoic acids from 2-ethyl hexanol
Process for preparing isononanoic acid proceeding from 2-ethylhexanol, characterized in that (a) 2-ethylhexanol is dehydrated to octene in the presence of a...
US-9,434,671 Nitrogen monoxide as cis/trans isomerization catalysts for unsaturated compounds
The present invention relates to a process of a cis/trans isomerization of an unsaturated compound A being selected from the group consisting of unsaturated...
US-9,434,670 Family of aryl, heteroaryl, O-aryl and O-heteroaryl carbasugars
The present invention relates to a compound of the following formula (I): as well as its process of preparation, pharmaceutical and cosmetics composition...
US-9,434,669 Cyclohexanols and their use in perfume compositions
The present invention is directed to novel fragrance compounds and their unexpected advantageous use in improving, enhancing or modifying a fragrance...
US-9,434,668 Process for the production of tertiary butyl phenols
The present invention relates to an improved process for the selective alkylation of phenols by reacting it with methyl tertiary butyl ether (MTBE) using...
US-9,434,667 Method for isolation of 1,3-propanediol from post-fermentation broth obtained by bioconversion
A method for isolation of 1,3-propanediol from post-fermentation broth is disclosed. The method generally involves the following steps: (1) biomass removal from...
US-9,434,666 Catalytic hydrogenation using complexes of base metals with tridentate ligands
Complexes of cobalt and nickel with tridentate ligand PNHP.sup.R are effective for hydrogenation of unsaturated compounds. Cobalt complex ...
US-9,434,665 Ruthenium complex and method for preparing methanol and diol
Provided is a method for preparing methanol and diol from cyclic carbonate, comprising: under a hydrogen atmosphere, in an organic solvent, and with the...
US-9,434,664 Preparation method for edge-fluorinated graphite via mechanic-chemical process
Disclosed is a method for producing edge-functionalized graphite or graphene with fluoro groups. According to the method, graphite is pulverized into smaller...
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