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Patent # Description
US-9,439,948 Degradable cage coated with mineral layers for spinal interbody fusion
A cage for facilitating fusion of bones, such as vertebrae, or fusion of adjacent bone surfaces is disclosed. In one form, the cage includes a plurality of...
US-9,439,947 Therapy for radiation-induced lung injury
Methods are disclosed for therapy of radiation-induced lung injury and other lung diseases using R-spondin1.
US-9,439,946 Reconstituted high density lipoprotein formulation and production method thereof
A reconstituted high density lipoprotein formulation having relatively low toxicity comprises an apolipoprotein such as ApoAI or fragment thereof, a lipid and a...
US-9,439,945 Isolated nucleotide sequences encoding GDF traps
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including...
US-9,439,944 Agent that inhibits angiogenesis and metastasis targeting mTOR signaling pathway
The present invention relates to a novel function of Msx1 protein for inhibiting tumor angiogenesis and metastasis by targeting mTOR (mammalian target of...
US-9,439,943 Use of melanocortins to treat insulin sensitivity
The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the...
US-9,439,942 Peptides and use thereof in the treatment of large cell lung cancer
A method of treating large cell lung cancer in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically...
US-9,439,941 Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
The present invention provides methods, compositions, and kits wherein nanomaterials are used for inhibiting cancer stem cell division, colony formation,...
US-9,439,940 Topical transdermal method for delivering nutrients through the skin for expeditied wound healing and skin...
The present invention relates to liquid application for skin rejuvenation created from specific amino acids, lipids, nucleic acids and vitamins. This collection...
US-9,439,939 Heavy metals defense
A dietary supplement comprising powdered ingredients: a) dehydrated seaweed: 40-60 wt. %, b) seawater extract: 20-40 wt. %, c) grape seed powder: 10-20 wt. %,...
US-9,439,938 Use of avocado skin for obtaining an avocado unsaponifiable material enriched with saturated aliphatic...
The present invention relates to the use of avocado peels in order to obtain avocado unsaponifiable enriched in saturated aliphatic hydrocarbons and in sterols,...
US-9,439,937 Rat-eye bean extract improving blood glucose control and bioactivity and method of producing the same
Provided are a rat-eye bean extract improving blood glucose control and bioactivity, which is produced from rat-eye beans as health food so as to be able to...
US-9,439,936 Inhibitor of inflammatory conditions
The invention relates to Boswellia frereana and particularly an extract of same for treating a range of inflammatory disorder or conditions selected from the...
US-9,439,935 Recombinant rift valley fever (RVF) viruses and methods
Described herein are recombinant RVF viruses comprising deletions in one or more viral virulence genes, such as NSs and NSm. The recombinant RVF viruses,...
US-9,439,934 Application of an attenuated salmonella typhimurium, its genetically engineered bacterium in preparing drugs...
The current invention discloses an attenuated Salmonella typhimurium, a genetically engineered bacterium and applications thereof in preparing drugs for the...
US-9,439,933 Skin properties improving agent for oral administration
Disclosed is a skin property-improving agent which exerts excellent effects by oral administration. The skin property-improving agent for oral administration...
US-9,439,932 Pluripotent cells
Pluripotent cells that are immunopositive for both the neural progenitor marker nestin and a pluripotent cell marker are provided. The cells exhibit rapid...
US-9,439,931 Administering umbilical cord blood-derived mesenchymal stem cells to treat nerve injury
A use of a composition comprising umbilical cord blood-derived mesenchymal stem cells for inducing differentiation and proliferation of neural precursor cells...
US-9,439,930 Rapid infusion of autologous bone marrow derived stem cells
The present invention relates to a method and composition for the aspiration, processing, testing and infusion of bone marrow derived stem cells, as an adjuvant...
US-9,439,929 Treatment of graft-versus-host disease
This present application describes a therapeutic agent for treating acute or chronic graft-versus-host disease using clonal marrow stem cells (cMSCs) as active...
US-9,439,928 Method for combined conditioning and chemoselection in a single cycle
A method of radiation-free hematopoietic stem cell (HSC) transplantation comprises administering to a mammalian subject one or two doses of 2 to 10 mg/kg body...
US-9,439,927 Treatment of inflammatory bowel disease
The invention relates to the treatment of inflammatory bowel disease, also termed IBD, including ulcerative colitis and Crohn's disease. To this end, the...
US-9,439,926 Topical systems and methods for treating sexual dysfunction
The present invention generally relates to compositions and methods for topical or transdermal delivery, and treatment of sexual dysfunction. The compositions...
US-9,439,925 Methods and compositions for treating wounds utilizing chitosan compounds
Described herein are methods of treating wounds, the method comprising administering to a subject an effective amount of a composition comprising a soluble or...
US-9,439,924 Therapeutic miRNAs for treating heart and skeletal muscle diseases
The present disclosure describes the role for miR-322(424)/503 in the differentiation of cardiac precursor cells. Thus, the use of these molecules in the...
US-9,439,923 Compositions and methods for treating retrovirus infections
The present invention relates to at least one nucleic acid (i) comprising or consisting of or (ii) encoding a nucleic acid comprising or consisting of, a...
US-9,439,922 Tat DNA sequences, gene constructs, vaccine and processes thereof
The present invention relates to non toxic, immunogenic viral Tat DNA sequences comprising wherein the Tat Sequence is rendered non toxic and immunogenic by...
US-9,439,921 Pharmaceutical formulations comprising high purity cangrelor and methods for preparing and using the same
The present invention relates to high purity cangrelor, pharmaceutical formulations comprising high purity cangrelor as an active ingredient, methods for...
US-9,439,920 Composition for the management of nausea and vomiting
A pharmaceutical dosage system comprising (a) an effective amount of one or more of Doxylamine, an analog thereof, a derivative thereof, a prodrug thereof, a...
US-9,439,919 Uridine diphosphate compounds as mobilizers of hematopoietic progenitor cells
The present invention provides for compositions and methods for administering one or more UDP compound, alone or in combination with another hematopoietic...
US-9,439,918 Methods for treating gastrointestinal diseases
Described herein are macrolide and ketolide antibiotics and pharmaceutical compositions, methods, and uses thereof for treating gastrointestinal diseases.
US-9,439,917 Anti-blepharitis compositions and their use
Compositions and methods for the prevention and treatment of blepharitis, where the compositions include verbascoside, oligopeptide-10, and sulfonated shale...
US-9,439,916 Composition for decelerating the aging in the organism and for extending the life time thereof and the use of...
The invention relates to pharmacology, medicine and gerontology, in particular to a class of chemical structures (1) which can be used in compositions, in the...
US-9,439,915 Activated nitric oxide donors and methods of making and using thereof
Described herein are compositions useful in anticancer treatment. The compositions are composed of (a) an O.sup.2-aryl substituted diazeniumdiolate and (b) an...
US-9,439,914 Methods for making active crystalline materials
The present invention relates to an active crystalline material, especially an active multicomponent crystalline material such as a salt or a cocrystal, which...
US-9,439,913 Fat-soluble vitamin formulations
The present disclosure generally pertains to formulations containing two or more fat-soluble vitamins, lemon oil, and zinc. Also disclosed are kits containing...
US-9,439,912 Androgen receptor down-regulating agents and uses thereof
The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length...
US-9,439,911 Topical formulations comprising a steroid
The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are...
US-9,439,910 Fe(III)-pyrazine complex compounds for treatment and prophylaxis of iron-deficiency phenomena and...
The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment...
US-9,439,909 Compositions and methods for sensitizing a neoplastic cell to radiation
The invention provides for the use of radiation sensitizing agents in combination with radiation for the treatment of neoplasia, methods for the identification...
US-9,439,908 Cross-linking composition delivered by iontophoresis, useful for the treatment of keratoconus
An improved formulation of an ophthalmic composition contains riboflavin, as cross-linking agent of corneal collagen, administered by corneal iontophoresis,...
US-9,439,907 Method of forming an aerosol for inhalation delivery
The present application relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol...
US-9,439,906 Dosing regimen associated with long acting injectable paliperidone esters
The present invention provides a method of treating patients in need of treatment with long acting injectable paliperidone palmitate formulations.
US-9,439,905 Risperidone-containing implants and methods of use thereof
The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The...
US-9,439,904 Pyrimidine compounds and their use as gamma secretase modulators
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical...
US-9,439,903 Process for the preparation of amorphous imatinib mesylate
The field of the invention relates to a process for the preparation of amorphous imatinib mesylate. In particular, the invention relates to a process for the...
US-9,439,902 Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives
Compounds of Formula (A) and (B) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by sodium-glucose...
US-9,439,901 Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives
Compounds of Formula (A) and (B) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by sodium-glucose...
US-9,439,900 Abuse-resistant pharmaceutical composition for the treatment of opioid dependence
There is provided pharmaceutical compositions for the treatment of e.g. opioid dependency comprising microparticles of a pharmacologically-effective amount of...
US-9,439,899 Cancer therapy using a combination of HSP90 inhibitors with topoisomerase I inhibitors
A pharmaceutical combination comprising a topoisomerase I inhibitor, and an Hsp90 inhibitor according to the following formulae (I) (Ia) a tautomer, or a...
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