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Patent # Description
US-9,439,898 Methods for novel drug discovery, treatment and selective targeting for gefitinib-resistant non-small-cell lung...
The present invention relates to methods for novel drug discovery, treatment and selective targeting for Gefitinib-resistant non-small-cell lung cancer (NSCLC)...
US-9,439,897 Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders
Methods for the treatment of a cell proliferation disease or disorder in a subject, involving applying a psoralen derivative lacking a DNA cross-linking motif...
US-9,439,896 Quinolines as FGFR kinase modulators
The invention relates to new quinoline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the...
US-9,439,895 Methods of treating pruritic conditions mediated through non-histaminergic mechanisms in diabetic patients
Described herein are methods of treating a mammal in need of treatment for non-histaminic pruritus by administering to the mammal in need thereof a...
US-9,439,894 Myeloid differentiation inducing agents
Myeloid differentiating agents can be used in the treatment of myeloid proliferative disorders.
US-9,439,893 1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,- ...
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain compounds of the following formula (for...
US-9,439,892 Macrolide particulates, methods for preparation, and medical devices associated therewith
The disclosure provides macrolide particulates including a macrolide therapeutic agent such as rapamycin at high concentration in the particulate. In one method...
US-9,439,891 Methods for treating hyperuricemia in patients with gout using halofenate or halofenic acid and a second...
Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition...
US-9,439,890 Triazolone compounds as mPGES-1 inhibitors
The present disclosure is directed to compounds of formula (I), and pharmaceutically acceptable salts thereof, as mPGES-1 inhibitors. These compounds are...
US-9,439,889 Methods employing wolbachia FtsZ as a target for albendazole sulfone
Compositions and Methods are described in which Albendazole sulfone binds to Wolbachia FtsZ providing anti filarial activity.
US-9,439,888 Tetrazolones as a carboxylic acid bioisosteres
The present disclosure provides compounds that include a tetrazolone derivative of a carboxyl group of an active agent. This disclosure also relates to...
US-9,439,887 Anti-cancer compositions and methods
Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present...
US-9,439,886 Methods for producing crosslinked flavonoid hydrogels
There is provided methods for producing a hydrogel comprising conjugates of a hydrogel forming agent and a flavonoid including a method for producing a hydrogel...
US-9,439,885 Method for inhibiting the growth of bacteria
The present invention is directed to a method for inhibiting the growth of pathogenic bacteria in an infant formula comprising supplementing the infant formula...
US-9,439,884 Methods for the treatment of immune disorders
The invention features methods of treating an immune disorder characterized by elevated Pin1 marker levels in a subject by administering a retinoic acid...
US-9,439,883 3,5,3'-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof
The invention regards the use of triiodothyronine sulfate, commonly named T.sub.3S, as a medicament having thyromimetic activity for the treatment of...
US-9,439,882 Compounds and compositions for the treatment of cancer
New uses for phenylketone carboxylate compounds and substituted aromatic compounds of Formula I, Formula I.1, Formula I.2, Formula IA, Formula IB, Formula IC...
US-9,439,881 Acrylamide compounds and use thereof for inhibiting apoptosis
The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate of the compound, and to a composition...
US-9,439,880 Method for treating inflammation and pain
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and .omega.-(methylsulfonyl)alkylamine or...
US-9,439,879 Treatment of urinary incontinence using nitrone spin traps
Urinary incontinence is treated by administration of pharmaceutical compositions containing at least one nitrone spin trap such as .alpha.-phenyl t-butyl...
US-9,439,878 Use of lumefantrine and related compounds in the treatment of cancer
The present application discloses the use of the anti-malarial drug lumefantrine and related compounds in the treatment of cancer.
US-9,439,877 Small molecule inhibitors of Dusp6 and uses therefor
Compounds that stimulate fibroblast growth factor production, and thus cell growth are provided. Also provided are compositions comprising the compounds and...
US-9,439,876 Method of treating microbial infections
Methods of inhibiting or preventing the proliferation of a fungus and/or a bacteria in a living organism, in water, in air, and/or on surfaces, include...
US-9,439,875 Anxiolytic effect of pterostilbene
We report for the first time that pterostilbene, a natural analog of resveratrol, shows anxiolytic-like action by downregulating phosphorylated levels of ERKs...
US-9,439,874 Food composition for nourishing, maintaining and cultivating a variety of stem cells and a method for...
A food composition for nourishing, maintaining and cultivating a variety of stem cells, the food composition includes grape skin or polygonum cuspidatum root...
US-9,439,873 Application aid
The invention relates to a transdermal therapeutic system (10) comprising an active ingredient depot (11) that contains at least one active ingredient,...
US-9,439,872 Oral film-form base and preparation
The present invention aims to provide an oral film-form base and an oral film-form preparation which have a rapid dissolution profile in the mouth and...
US-9,439,871 Method for preparing nano particles
The present invention relates to a method for manufacturing nano-scale particles of an active material. More particularly, the present invention relates to a...
US-9,439,870 Active agent microparticles
The present invention concerns polymeric-enveloped microparticles including at least one HASE type acrylic copolymer, at least one solid-liquid phase change...
US-9,439,869 Nanoshells on polymers
Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
US-9,439,868 Supramolecular capsules
Provided is a capsule having a shell of material that is a supramolecular cross-linked network. The network is formed from a host-guest complexation of...
US-9,439,867 Method for manufacturing a compound danshen dripping pill
A method for manufacturing a compound danshen dripping pill is disclosed. The method comprises: mixing powders of active substances with an excipient in a...
US-9,439,866 Trazodone composition for once a day administration
The invention relates to a once a day formulation of trazodone or a trazodone derivative. The formulation contains trazodone or a trazodone derivative and a...
US-9,439,865 Coating film, and granules and tablets each utilizing same
A coating film comprising ethyl cellulose as a component A and an (ethyl acrylate)-(methyl methacrylate) copolymer or a plasticized vinyl acetate polymer as a...
US-9,439,864 Solvent extraction from biodegradable microparticles
Embodiments may include a method for reducing a solvent concentration in a plurality of microparticles. The method may involve contacting a mixture including...
US-9,439,863 Pharmaceutical dosage form
This invention relates to pharmaceutical dosage forms, particularly to pH dependent pharmaceutical dosage forms with enhanced and/or prolonged distribution of a...
US-9,439,862 Phospholipid-based powders for drug delivery
Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the...
US-9,439,861 Microspheres useful for therapeutic vascular embolization
Provided herein, for example, are microspheres comprising a gelatin or gelatin substitute and a copolymer of a N-tris-hydroxymethyl methylacrylamide monomer...
US-9,439,860 Fenofibrate formulation
Various fenofibrate dosage forms contain a plurality of beads or particles, where the beads or particles include a pharmaceutical composition comprising...
US-9,439,859 Adjuvant incorporation in immunoanotherapeutics
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable...
US-9,439,858 Temperature sensitive liposome including cationic lipid and use thereof
Provided are a liposome including a cationic lipid, a pharmaceutical composition for the delivery of anionic drugs, and a method for delivering anionic drugs to...
US-9,439,857 Foam containing benzoyl peroxide
The present invention relates to foamable compositions for treating acne comprising benzoyl peroxide; to a therapeutic kit comprising such compositions; and to...
US-9,439,856 Method of preparing composition for delivering an anionic drug
Disclosed is an effective method of preparing a composition for delivering an anionic drug, the composition comprising an anionic drug as an active ingredient,...
US-9,439,855 Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form...
US-9,439,854 Liquid pharmaceutical formulations of palonosetron
The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron....
US-9,439,853 Form of administration of enkephalinase inhibitor
The present invention relates to a new formulation of an enkephalinase inhibitor, such as racecadotril or dexecadotril, the process for the preparation thereof,...
US-9,439,852 Methods of delivering pharmaceutical agents
Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological...
US-9,439,851 Gastric retention system
The present invention provides a novel gastric retention system in the form of a tablet or a capsule coated with an expandable coating, more particularly, with...
US-9,439,850 Use of pufas for treating skin inflammation
The present invention provides a compound which is a polyunsaturated fatty acid (PUFA) derivative of formula (I), ##STR00001## or a pharmaceutically...
US-9,439,849 Composition for preventing or alleviating skin wrinkles containing honeybush extract or fermented honeybush as...
Provided is a composition for preventing or alleviating skin wrinkles containing honeybush (Cyclopia intermedia) extract, a fraction thereof, or a fermented...
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