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Patent # Description
US-9,447,455 Methods and compositions for the target-localized anchoring of detectable label
Highly reactive functionalized substrates and linker molecules for use in the detection of molecular targets and other analytes of interest are provided as are...
US-9,447,454 Method of purifying RNA binding protein-RNA complexes
The present invention provides methods for purifying RNA molecules interacting with an RNA binding protein (RBP), and the use of such methods to analyze a gene...
US-9,447,453 Resolving genome fractions using polymorphism counts
Methods of reliably estimating genomic fraction (e.g., fetal fraction) from polymorphisms such as small base variations or insertions-deletions are disclosed....
US-9,447,452 Selective oxidation of 5-methylcytosine by TET-family proteins
The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification...
US-9,447,451 Device and methods for epigenetic analysis
Provided herein are methods and devices for single object detection. The methods and devices can be used to identify a plurality epigenetic markers on a genetic...
US-9,447,450 Red-shifted luciferins and methods of using same
Novel red-shifted luciferin derivatives and uses of those compounds are provided.
US-9,447,449 Recombinant mycobacteriophages for delivery of nucleic acids of interest into mycobacteria
Methods are provided for detecting mycobacteria in a sample, including clinical samples. Methods are also provided for determining susceptibility of...
US-9,447,448 Drone-based microbial analysis system
A drone-based microbial analysis system includes an electronic drone control facility including an electronic storage memory device. The storage memory device...
US-9,447,447 Method and apparatus for testing cardiotoxicity and evaluating cardiomyocytes
In the present invention, a cardiomyocyte cluster is disposed on a transparent substrate, and the quality of the cardiomyocytes is evaluated from the response...
US-9,447,446 Lipid multilayer microarrays and their use for cell culture screening
Provided is a device having one or more lipid multilayer arrays of lipid multilayer structures on a substrate. Each lipid multilayer structure encapsulates an...
US-9,447,445 Synthon formation
This disclosure provides, among other things, a composition comprising: a 5' exonuclease; a strand-displacing polymerase; and optionally a single strand DNA...
US-9,447,444 Biosynthesis of opiate alkaloids
The disclosure relates to a nucleic acid molecule isolated from a Papaver somniferum cultivar that produces the opiate alkaloid noscapine which comprises 10...
US-9,447,443 Method for producing 3-acetylamino-4-hydroxybenzoic acid
The present invention provides a method for conveniently and efficiently producing a 3-acetylamino-4-hydroxybenzoic acid-type compound that is a stable compound...
US-9,447,442 Production of biofuel from tissue culture sources
A method for the production of at least one fatty acid and/or oil from a plant cell suspension culture includes (i) maintaining a cell suspension culture of...
US-9,447,441 Method for producing polyhydroxyalkanoate having long main chain structure
A polyhydroxyalkanoate copolymer of 3HB (3-hydroxybutyrate), 3HP (3-hydroxypropionate) and 5HV (5 -hydroxyvalerate) disclosed. The polyhydroxyalkanoate can be...
US-9,447,440 Microorganisms for C4-dicarboxylic acid production
The present invention relates to isolated polypeptides having bicarbonate transporter activity and isolated polynucleotides encoding the polypeptides. The...
US-9,447,439 Microorganism producing 4-hydroxybutyrate and a method for producing 4-hydroxybutyrate in anaerobic condition...
A genetically modified microorganism comprising a polynucleotide encoding .alpha.-ketoglutarate synthase or a mutant thereof, and a polynucleotide encoding...
US-9,447,438 Acetyl-coA carboxylases
The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical...
US-9,447,437 Genetically engineered Torulopsis glabrata with enhanced extracellular secretion of pyruvic acid
The present invention provides a genetically engineered Torulopsis glabrata with enhanced extracellular secretion of pyruvic acid. T. glabrata strain was...
US-9,447,436 Production of saturated fatty alcohols from engineered microorganisms
Recombinant bacterial microorganisms are provided which comprise heterologous fatty acyl reductases ("FAR") polypeptides wherein said microorganisms have been...
US-9,447,435 Integrated processes for anaerobic conversion of hydrogen and carbon oxides to alcohol
Integrated processes are disclosed for the anaerobic bioconversion of syngas to alcohol wherein a gas substrate of carbon monoxide, hydrogen and carbon dioxide...
US-9,447,434 Use of chimeric nucleases to stimulate gene targeting
Gene targeting is a technique to introduce genetic change into one or more specific locations in the genome of a cell. For example, gene targeting can introduce...
US-9,447,433 Synthetic adeno-associated virus inverted terminal repeats
This invention relates to synthetic adeno-associated virus (AAV) inverted terminal repeats (ITRs) that exhibit altered activities compared to a naturally...
US-9,447,432 Method for producing induced pluripotent stem cells
An object of the present invention is to provide methods for producing iPS cells with low invasivity and high efficiency. The iPS cells can be produced with...
US-9,447,431 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal...
The present invention relates to a nucleic acid sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a...
US-9,447,430 Canola inbred line G2X0023AB
The present invention relates to a new and distinctive canola, designated G2X0023AB. Also included are seeds of canola G2X0023AB, to the plants, or plant parts,...
US-9,447,429 Method to trigger RNA interference
A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or...
US-9,447,428 Soybean transgenic event MON 87708 and methods of use thereof
The invention provides a transgenic soybean event MON 87708 plant and plants, plant cells, seeds, plant parts, and commodity products derived from event MON...
US-9,447,427 Production of FatA TE-overexpressing plants with improved tolerance to water deficit
The present invention relates to a method for increasing the tolerance of a plant to water deficit, which method comprises the overexpression in said plant of a...
US-9,447,426 Polynucleotide encoding NF-YB derived from jatropha and use thereof
By analyzing a Jatropha genome, NF-YB-encoding genes of SEQ ID NOs: 1 to 11, fragments of NF-YB-encoding genes of SEQ ID NOs: 12 and 13, and genes relating...
US-9,447,425 Transcription factor sequences for conferring advantageous properties to plants
The invention relates to plant homeobox (HB) protein family polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and...
US-9,447,424 Soybean ATPS promoter and its use in constitutive expression of transgenic genes in plants
The invention relates to gene expression regulatory sequences from soybean, specifically to the promoter of a soybean ATP sulfurylase (ATPS) and fragments...
US-9,447,423 Regulatory polynucleotides and uses thereof
The present disclosure provides compositions and methods for regulating expression of transcribable polynucleotides in plant cells, plant tissues, and plants....
US-9,447,422 Autonomous replication sequences and episomal DNA molecules
The present invention provides autonomous replication sequences (ARSs) isolated from Nannochloropsis that support the replication of episomal DNA molecules...
US-9,447,421 Methods for Agrobacterium-mediated transformation of sugar cane
The present invention provides methods for Agrobacterium-mediated transformation of sugar cane (Saccharum spp.) comprising introducing a nucleotide sequence of...
US-9,447,420 RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression...
The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to...
US-9,447,419 RNAi-mediated inhibition of tumor necrosis factor .alpha.-related conditions
RNA interference is provided for inhibition of tumor necrosis factor .alpha. (TNF.alpha.) by silencing TNF.alpha. cell surface receptor TNF receptor-1 (TNFR1)...
US-9,447,418 Pro- and anti-angiogenic treatments
The invention provides a method of selectively pro-oranti-angiogenic treatment of a mammalian subject, comprising site-specific control of alternative splicing...
US-9,447,417 Multiple exon skipping compositions for DMD
Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof...
US-9,447,416 Multiple exon skipping compositions for DMD
Provided are antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon skipping, and methods of use thereof...
US-9,447,415 Antisense oligonucleotides for inducing exon skipping and methods of use thereof
An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.
US-9,447,414 Methods and compositions involving miRNA and miRNA inhibitor molecules
The present invention concerns methods and compositions for introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover,...
US-9,447,413 Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric...
US-9,447,412 Oligomeric compounds and compositions for use in modulation of small non-coding RNAS
Compounds, compositions and methods are provided for modulating the expression and function of small non-coding RNAs. The compositions comprise oligomeric...
US-9,447,411 Methods and compositions for single cell expression profiling
Methods of obtaining a single cell expression profile from a target mammalian cell are provided. Aspects of the methods include contacting a cellular sample...
US-9,447,410 T cell receptor display
A proteinaceous particle, for example a bacteriophage, ribosome or cell, displaying on its surface a T-cell receptor (TCR). The displayed TCR is preferably a...
US-9,447,409 Lysis buffers for extracting nucleic acids
The present teachings relate to the extraction of nucleic acid from solid materials. Provided are useful compositions, methods and kits for obtaining nucleic...
US-9,447,408 Method of efficiently establishing induced pluripotent stem cells
The present invention provides a method of improving the efficiency of establishment of induced pluripotent stem (iPS) cells by inhibiting p38 function in the...
US-9,447,407 Double coating procedure for the membranes of bioartificial kidneys
The present invention generally relates to modified substrates such as membranes for use in bioartificial organs, such as bioartificial kidneys, and other...
US-9,447,406 Chemically modified cystathionine beta-synthase enzyme for treatment of homocystinuria
The invention provides reagents and methods for enzyme replacement therapy using chemically modified species of human cystathionine .beta.-synthase (CBS) to...
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