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Patent # Description
US-9,457,044 Methods and compositions for wound healing
Methods and compositions comprising combinations of one or more anti-connexin agents and one or more other agents useful for the promotion and/or improvement of...
US-9,457,043 Combination therapy using c-Met inhibitor and c-Myc inhibitor
A method of preventing and/or treating a cancer including co-administering a c-Met inhibitor and a c-Myc Inhibitor to a subject in need thereof, a...
US-9,457,042 Pharmaceutical combination comprising a CIP2A silencing agent for use in the treatment of a hyperproliferative...
The invention is based on a finding that silencing CIP2A (KI-AA1524) gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule...
US-9,457,041 Controlled release nanoparticles and methods of use
Provided herein are nanoparticles that include a lipid layer and a compartment surrounded by the lipid layer. The lipid layer may include a lipid and a...
US-9,457,040 Effective treatment of esophageal adenocarcinoma using triciribine and related compounds
The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat esophogeal adenocarcinoma by one or a...
US-9,457,039 2'-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
2'-disubstituted substituted nucleoside derivatives of formula (I) and pharmaceutically acceptable salts thereof are disclosed: (1), wherein A is N.sup.3 or...
US-9,457,038 Administration of avermectin/milbemycin compounds for the treatment of ophthalmic pathologies
Administration of at least one compound of the family of the avermectins or of the family of the milbemycins, notably ivermectin, is useful for the treatment of...
US-9,457,037 Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the...
A combination composition comprising as active ingredients L-carnitine or propionyl L-carnitine, troxerutine, diosmine and hesperidine, useful for the...
US-9,457,036 Compositions and methods for combination antiviral therapy
The present invention relates to therapeutic combinations of [2-(6-amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester...
US-9,457,035 Antiviral compounds
The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include...
US-9,457,034 Magnetic microsphere and method of forming a microsphere
The microspheres have many possible applications including smart drug delivery, breaking and damper devices. In one arrangement, a microsphere comprises a shell...
US-9,457,033 Steroid alkaloids and uses thereof as antimicrobial agents against electron transport-deficient microbes and as...
The present invention includes novel compounds based on the tomatidine skeleton as well as composition comprising these compounds alone and in combination with...
US-9,457,032 Therapeutic agent for renal failure
A therapeutic agent for renal failure including, as an active ingredient, a 4,8-inter-m-phenylene prostaglandin I.sub.2 derivative, and also a method for...
US-9,457,031 Antibacterial protein kinase inhibitors
Methods of treating bacterial infection by in a subject by administering a pharmaceutical composition including a celecoxib derivative are described. The...
US-9,457,030 Compositions and methods for the treatment of juvenile neuronal ceroid lipofuscinosis and related disorders
Provided are materials and methods for the prevention and treatment of Juvenile Neuronal Ceroid Lipofuscinosis comprising administration of an effective amount...
US-9,457,029 Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin
The present invention relates to methods for preventing or treating of metabolic disorders and related conditions, such as in certain patient groups.
US-9,457,028 Pharmaceutical composition for use in prevention or treatment of cancer
Abacavir, a nucleoside analog reverse transcriptase inhibitor, has been found to exhibit an anti-cancer activity on ATL cells in vitro without inhibiting DNA...
US-9,457,027 Compounds for use in treatment of mucostis
The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof,...
US-9,457,026 Methods for producing aripiprazole suspension and freeze-dried formulation
Disclosed are a method for producing an aripiprazole suspension, wherein the aripiprazole has a mean particle size of 1 to 10 .mu.m, the method comprising the...
US-9,457,025 Compositions and methods comprising bupropion or related compounds for sustained delivery of dextromethorphan
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically,...
US-9,457,024 Compositions, dosage forms, and co-administration of an opioid agonist compound and a non-steroidal...
The present invention relates generally to the co-administration of an opioid agonist compound and an analgesic compound. In addition, the invention relates to,...
US-9,457,023 Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
US-9,457,022 Methods and compositions for treating or preventing symptoms of hormonal variations
The present invention relates to methods, compositions, and kits for treating or preventing symptoms of hormonal variation. The method comprises the steps of...
US-9,457,021 Liquid pharmaceutical formulations of palonosetron
The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron....
US-9,457,020 Liquid pharmaceutical formulations of palonosetron
The present invention relates to shelf-stable liquid formulations of palonosetron for reducing chemotherapy and radiotherapy induced emesis with palonosetron....
US-9,457,019 Methods for inhibiting tie-2 kinase useful in the treatment of cancer
The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravazation, dissemination,...
US-9,457,018 Method for combating adverse effects arising from antipsychotic treatment
This invention relates to a method for combating adverse effects arising from antipsychotic treatment. The invention furthermore relates to novel pharmaceutical...
US-9,457,017 Treatment of heart failure
The invention relates to perhexiline, or a pharmaceutically acceptable salt thereof, for use in the treatment of heart failure, as well as to a method for...
US-9,457,016 Methods for treating polycystic kidney disease
Methods for treating autosomal dominant polycystic kidney disease (ADPKD) are described herein. More particularly, methods described herein relate generally to...
US-9,457,015 2-aminothiazole derivative and anti-cancer composition comprising same as active ingredient
The present invention relates to a novel 2-aminothiazole derivative, N-(5-(4-fluorophenyl)thiazole-2-il)-3-(furan-2-il)propane amide and to a use thereof as an...
US-9,457,014 Cysteine prodrugs
Novel cysteine prodrugs and their use in the treatment of diseases and/or conditions, including but not limited to diseases and/or conditions of the Central...
US-9,457,013 Method for treating a neurological disorder associated with hypoxia using a small moleucule MIF inhibitor
Methods are provided for treating pathologies associated with hypoxia with an MIF inhibitor. Methods are also provided for treating a subject having, or at risk...
US-9,457,012 Transdermal absorption preparation
A transdermal absorption preparation comprising (1) a support, and (2) a rubber-based adhesive layer comprising 4-(2-methyl-1-imidazolyl)-2,2-diphenylbutylamide...
US-9,457,011 Compositions and methods for the treatment of acid-related gastrointestinal disorders containing a dithiolane...
The present disclosure describes a treatment for acid related gastrointestinal disorders. The compounds described herein are known gastric acid secretion...
US-9,457,010 Compositions for use in treating or preventing metabolic stress-induced lung injury and methods for increasing...
The present invention relates to a composition comprising (i) choline and (ii) a compound selected from the group consisting of palmitate, vitamin C and vitamin...
US-9,457,009 Methods and compositions for preventing and treating auditory dysfunctions
The invention provides methods for treating auditory impairments in a subject in need of treatment comprising administering to said subject an effective amount...
US-9,457,008 Joint product comprising synephrine and topiramate
The present invention provides a joint product comprising synephrine and topiramate, in which the synephrine or salt thereof is administered in form of...
US-9,457,007 Prenylflavanone compounds for modulating diabetes
The present invention is directed to a novel use of prenylflavanone compounds for control of blood glucose and treatment or prevention of diabetes.
US-9,457,006 Diagnosis and treatment methods for entry of gastrointestinal contents into respiratory tract
A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The...
US-9,457,005 Compositions and methods for increasing insulin sensitivity
Methods and compositions for treating a blood glucose condition involve identifying a suitable subject and administering an effective amount of a composition...
US-9,457,004 Opsin-binding ligands, compositions and methods of use
Compounds are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in...
US-9,457,003 Phenyl carbamate compound and a composition for preventing or treating a nerve gas-induced disease comprising...
The present invention relates to a composition for preventing or treating a nerve gas-induced disease comprising a phenyl carbamate compound and a method for...
US-9,457,002 Antimicrobial compositions comprising glyceryl nitrates
Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a...
US-9,457,001 Internal composition
An object of the present invention is to provide an internal composition capable of exerting various physiological functions such as a brain-function improving...
US-9,457,000 Gamma-polyglutamic acid-based intraocular irrigation solutions
Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) .gamma.-polyglutamic acid (.gamma.-PGA) and/or salt thereof in...
US-9,456,999 Organosulfur compounds for the prevention and treatment of neurodegenerative diseases
S-allylmercapto-N-acetylcysteine and related compounds are disclosed which can be administered in order to provide protection from the formation of...
US-9,456,998 Selective inhibitors of undifferentiated cells
Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions...
US-9,456,997 Selective inhibition of .beta.1-adrenergic receptors for the treatment of pediatric heart failure
Provided are methods of treating heart failure in children using B1-selective adrenergic receptor antagonists, alone or in combination with other agents,...
US-9,456,996 Formulations of dimethyl trisulfide for use as a cyanide antidote
Dimethyl trisulfide antidote compositions may be used to as a cyanide poisoning antidote. Formulations of dimethyl trisulfide may be made in an aqueous solvent...
US-9,456,995 Methods for inhibition of BNIP3 and prevention and treatment of ischemia reperfusion injury by tetra-O-methyl...
Provided herein are methods for prevention and treatment of ischemia-reperfusion (IR) injury in the cardiac myocytes of a subject, by administration to the...
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