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Compositions and methods for the treatment of meibomian gland dysfunction
Described herein are compositions and methods for the treatment of meibomian gland dysfunction. Said compositions and methods comprise keratolytic agents, such...
The present invention relates to modified oligonucleotides of 5-50 nucleotide residues, wherein at least 25% of the nucleotides are independently modified at...
Use of PDE III inhibitors for the reduction of heart size in mammals
suffering from heart failure
The invention relates to the use of a phosphodiesterase type III (PDE III) inhibitor or Ca.sup.2+-sensitizing agent or a pharmaceutically acceptable derivative...
Compositions and methods for reducing or preventing metastasis
Compositions comprising glucopyranosyl lipid adjuvant (GLA) and methods for reducing or preventing the formation of cancer metastasis utilizing same are...
Method for treating abnormal polyglutamine-mediated disease
A method for treating an abnormal polyglutamine-mediated disease is disclosed, which comprises: administering a pharmaceutical composition comprising a...
Pharmaceutical composition of doxycycline with reduced food effect
The present invention relates to a once daily tablet comprising doxycycline at sub-antibiotic dose and one or more pharmaceutically acceptable excipients,...
Dissolution of amyloid fibrils by flavonoids and other compounds
Methods for disrupting amyloid fibrils in a subject, comprising combining an effective amount of a .beta.-2 microglobulin fibril disrupting compound with a...
Methods of treating patients co-infected with HIV and tuberculosis
The disclosure describes methods for treatment of patients co-infected with HIV and tuberculosis, wherein the patient receives effective amounts of...
Individual 5-fluorouracile dose optimization in folfiri treatment
The present invention belongs to the field of improved personalized medicine. More precisely, the present invention relates to a method for progressively...
The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related...
A composition of an antitussive, a decongestant, or an antihistamine to treat upper respiratory and oral pharyngeal congestion and related symptoms in a patient.
Methods of treating disease-induced ataxia and non-ataxic imbalance
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic...
Sulfonyl-substituted bicyclic compounds as PPAR modulators for the
treatment of non-alcoholic steatohepatitis
Disclosed herein are new methods of treatment of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and other fibrotic diseases of...
Osteopontin production inhibitor containing dictyopyrone derivative or
dihydrodictyopyrone derivative as active...
Disclosed herein is an osteopontin production inhibitor capable of preventing a disease resulting from increased production of osteopontin. The osteopontin...
Methylphenidate derivatives and uses of them
The present invention provides methods of using compounds of formula I: ##STR00001## and salts and prodrugs thereof, wherein n, R.sup.1 and R.sup.2 are defined...
Treatment for dopaminergic disorders
The present invention provides systems, compositions and methods for treatment of dopaminergic disorders (e.g., Parkinson's disease) using the combination of a...
Pharmaceutical containing PPAR-delta agonist
A preparation containing [3-[2-[4-isopropyl-2-(4-trifluoromethyl)phenyl-5-thiazolyl]ethyl]-5-methy- l-1,2-benzisoxazol-6-yl]oxyacetic acid, ...
Calcium flux agonists and methods thereof
Calcium flux agonists are used to enhance a TLR- or NOD-mediated stimulus and to so increase an immune response of a host and reduce healing time. Preferred...
Provided herein are stable lisinopril oral liquid formulations. Also provided herein are methods of using lisinopril oral liquid formulations for the treatment...
Composition for topical use
The use, as a dermatological or cosmetic ingredient, of compounds capable of transiently interacting with the AhR receptor (aryl hydrocarbon receptor) as agents...
Doxepin isomers and isomeric mixtures and methods of using the same to
treat sleep disorders
The invention relates to use of the cis-(Z) isomer or isomeric mixtures containing specified ratios of the cis-(Z) and trans-(E) isomers of doxepin, metabolites...
Treatment of molluscum contagiosum
Methods for treating molluscum contagiosum warts include identifying a human with one or more molluscum contagiosum warts and applying an anti-infective...
Short acting phenylalkylamine calcium channel blockers and uses thereof
The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart...
Ophthalmic solution for absorbing ultraviolet radiation and method for
absorbing ultraviolet radiation
An ophthalmic solution is provided. The ophthalmic solution includes an ultraviolet-A absorber and an ultraviolet-B absorber. The ophthalmic solution has a...
Compounds and methods for modulating vascular injury
Methods of modulating healing response to vascular injury and/or vascular scarring in a subject are provided. As such, aspects of the disclosure relate to the...
Composition for improving membrane composition and functioning of cells
It has now been found that after administration to a diseased person or person that is at risk for developing such disease of a neutraceutical or pharmaceutical...
Antimalarial drug which contains 5-aminolevulinic acid or derivative
thereof as active ingredient
Provided is an antimalarial drug which is useful for prevention and treatment of infectious diseases caused by malaria parasites. A preventive and/or...
Pharmaceutical composition for the treatment of type-1 diabetes
A composition for the prevention or treatment of type I diabetes in a subject, said composition comprising a GABAergic and incretin exemplified by GABA and...
Compositions and methods for treating obesity and obesity-related
The present invention relates to the field of obesity. More specifically, the present invention provides methods and compositions useful in treating obesity and...
Material and methods for treating developmental disorders including
comorbid and idiopathic autism
The present invention is directed to a method of treating a subject with autism spectrum disorder by administering an acetylaminopropane sulfonate. The...
Sulfonamide compounds for inhibition of metastatic tumor growth
Therapeutic ureido-sulfonamide compositions having compounds with the formula R-Q-Ar--SO.sub.2NH.sub.2 are disclosed, which compounds selectively inhibit CAIX...
Chemosensory receptor ligand-based therapies
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases,...
Human gastrointestinal microbiome modulating food supplement for improving
blood glucose regulation
A formulation to increase the ratio of gastrointestinal microbiota in phylum Bacteroidetes to microbiota of Firmicutes phylum preferably includes about 20-60...
Methods for the treatment of tinnitus induced by cochlear excitotoxicity
The invention relates to methods for the prevention and/or treatment of tinnitus induced by cochlear excitotoxicity. In these methods, a pharmaceutical...
Visual performance and/or macular pigmentation
Disclosed is a composition comprising MZ for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human...
Controlled release compositions comprising a combination of isosorbide
dinitrate and hydralazine hydrochloride
The invention relates to a controlled release composition comprising a combination of isosorbide dinitrate and hydralazine, such as hydralazine hydrochloride,...
Granular material for orally fast disintegrating tablets
The use of a granular material which is for orally fast disintegrating tablets and comprises at least one kind of water soluble polymer and tannic acid allows...
Tablet having improved elution properties
The present invention provides a tablet having improved dissolution property, which comprises ...
Delayed release pharmaceutical composition of mesalamine
The invention relates to a delayed release pharmaceutical composition of mesalamine comprising: a) granules comprising mesalamine or pharmaceutically acceptable...
Self-gelling alginate systems and uses thereof
Kits and compositions for producing an alginate gel are disclosed. The kits and compositions comprise soluble alginate and insoluble alginate/gelling ion...
Compositions for pulmonary delivery of long-acting muscarinic antagonists
and associated methods and systems
Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting .beta..sub.2 adrenergic receptor...
Dosage form exhibiting rapid disperse properties, methods of use and
process for the manufacture of same
A rapidly dispersing dosage form is described. The dosage form releases its active ingredients within a period of less than about ninety seconds. These dosage...
Oral gel for relief of tooth pain
Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling...
Treatment of erectile dysfunction and other indications
The present invention generally relates to the transdermal delivery of various compounds. In some aspects, transdermal delivery may be facilitated by the use of...
Inhalation-type pharmaceutical composition for the treatment of
Alzheimer's disease and preparation method thereof
The present invention provides an inhalation-type pharmaceutical composition for Alzheimer's disease and preparation method thereof, comprising a first gas and...
Treatment and composition for achieving skin anti-aging benefits by
corneum protease activation
Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance,...
Cosmetic compositions and uses thereof
Disclosed is a composition and methods for its use to reduce the appearance of cellulite and improve skin texture comprising a combination of one or more of...
Topical skin care formulations comprising plant extracts
Disclosed is a method of topically applying Myriophyllum spicatum extract to skin, the method comprising topically applying a composition comprising...
Topical macqui berry formulation
The present invention provides a topical formulation and method of use where the formulation comprises macqui berry or a macqui berry extract containing...
Make-up cosmetic composition containing MQ silicone resin and propyl
The present invention relates to a make-up cosmetic composition containing MQ silicone resin and propyl silsesquioxane resin, and, more specifically, relates to...