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Patent # Description
US-9,468,661 Pyrrolidine derivatives and their use as complement pathway modulators
The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as complement...
US-9,468,660 Antinematodal methods and compositions
There are provided methods and compositions useful in cell-cell fusion using Fusion Family (FF) proteins of nematode origin. There are further provided...
US-9,468,659 Nutraceutical supplement with Lactobacillus rhamnosus
Compositions and uses thereof include an admixture of a probiotic and natural phytochemicals that can affect an individual's stem cells and the inflammatory...
US-9,468,658 Probiotic recolonisation therapy
The present invention relates to pharmaceutical compositions suitable for the treatment of chronic diseases associated with the presence of abnormal or an...
US-9,468,657 Lactic acid bacterium agent for improving lipid metabolism
This invention provides an effective means or method for improving lipid metabolism, and a means or method for treatment or prevention of diseases or disorders...
US-9,468,656 Stem cell preparations and methods of use
The present invention relates to a method of preparing cells and in particular to a method of preparing breastmilk stem cells (BSCs) by isolation from...
US-9,468,655 Compositions and methods including recombinant B lymphocyte cell line including at least one endogenous gene...
Compositions and methods are disclosed herein for producing one or more immunoglobulins in an isolated B lymphocyte cell line. An isolated recombinant cell line...
US-9,468,654 Drug delivery compositions and methods
A drug delivery composition is disclosed which includes a triple salt proxy functional group and at least one amino acid functional group. A method of forming...
US-9,468,653 Method based on bismuth ion for the treatment and prevention of a disease caused by a Shiga toxin
The present invention relates to the a bismuth-based composition, particularly involving the use of bismuth ions, particularly the Bi.sup.+3 ion, for prevention...
US-9,468,652 Multipurpose dental gel
Some embodiments of the present disclosure include a dental gel formulation for protecting a user's teeth and gums from acid resulting from acid reflux disease...
US-9,468,651 Method of removing moles
A method for removing moles includes applying a composition containing potassium hydroxide, Beijing Er Guo Tou and talcum powder on the surface of moles on...
US-9,468,650 Inhibition of endosomal toll-like receptor activation
The present invention relates, in general, to pattern-recognition receptors (PRRs), including toll-like receptors (TLRs), and, in particular, to a method of...
US-9,468,649 Methods of treating epilepsy with transforming growth factor beta inhibitors
The present invention provides methods of treating epilepsy and other neurological disorders. The methods generally involve administering to an individual in...
US-9,468,648 Treatment including prebiotic composition for use with probiotics
Naturally occurring lecithins and/or oleic acid stimulate the growth and lactic acid producing activity of Lactobacillus and Bifidobacterium species of...
US-9,468,647 Methods for the treatment of endometriosis
Endometriosis, including endometriosis externa, endometrioma, adenomyosis, adenomyomas, adenomyotic nodules of the uterosacral ligaments, and endometriotic...
US-9,468,646 Increased dosage of efavirenz for the treatment of cancer
The invention is based on the finding that an increased daily dose of Efavirenz should be used for the treatment of cancer compared to the daily dose used in...
US-9,468,645 Highly soluble purine bioactive compounds and compositions thereof
The invention provides nutritional supplements, in powder, tablet or capsule dosage forms and aqueous formulations, containing one or more of the purine...
US-9,468,644 Aqueous compositions
Suggested is a non-therapeutic aqueous composition for topical application, comprising (a) at least one solid active agent having at 20.degree. C. a solubility...
US-9,468,643 PDE5 inhibitor compositions and methods for immunotherapy
The invention features methods and compositions featuring a PDE5 inhibitor for treating or preventing immunological-mediated disease in a subject.
US-9,468,642 Imidazopyrazines
The present invention relates to imidazopyrazine compounds of general Formula (I): in which X, R.sup.1, R.sup.2, R.sup.3a, R.sup.3b, R.sup.4a, R.sup.4b,...
US-9,468,641 Anti-inflammatory pharmaceutical composition comprising benzopyranyl tetracycles
Disclosed herein is an anti-inflammatory pharmaceutical composition comprising a benzopyranyl tetracycle compound represented by Chemical Formula 1 as an active...
US-9,468,640 Piperidin-4-yl-pyridazin-3-ylamine derivatives as fast dissociating dopamine 2 receptor antagonists
The present invention relates to compounds that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical...
US-9,468,639 Treating sexual desire disorders with flibanserin
The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.
US-9,468,638 Itraconazole formulations
Provided herein is a pharmaceutical injectable formulation of itraconazole (10 mg/g) where the formulation comprises a solubilizer, a nonionic...
US-9,468,637 Organic compounds
The present invention relates to a new use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of psychosis, schizophrenia, schizoaffective disorder,...
US-9,468,636 Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
The present disclosure provides an extended release pharmaceutical composition comprising oxycodone and acetaminophen that provides a rapid onset of analgesia,...
US-9,468,635 Fused ring compound for use as mineralocorticoid receptor antagonist
The present invention belongs to the technical field of medicine, relating in particular to: a fused ring compound as represented by Formula (I) for use as a...
US-9,468,634 Treatment of heart failure
The invention relates to perhexiline, or a pharmaceutically acceptable salt thereof, for use in the treatment of heart failure, as well as to a method for...
US-9,468,633 Oral controlled release dosage form
A dosage form that provides a controlled release solid dosage form for the oral administration of a central nervous system stimulant, preferably methylphenidate...
US-9,468,632 Methods and compositions for targeting cancer stem cells
The present invention relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present invention...
US-9,468,631 Method and compound for treatment of menopausal symptoms
The subject invention describes a method of use of Ropinirole.TM. to alleviate and control menopausal symptoms in women, and in particular, hot flashes. The...
US-9,468,630 Compositions and methods for treating conditions related to increased eosinophils
Disclosed herein are methods of treating diseases associated with increased numbers of eosinophils basophils, and/or neutrophils with R(+) pramipexole.
US-9,468,629 Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for...
The present disclosure provides substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes, of Formula I D-M-D ...
US-9,468,628 Autotaxin inhibitor compounds
Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such...
US-9,468,627 Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies
The present invention concerns the treatment of serotonergic dysregulation disorders and/or augmentation of serotonin levels in the brain by add-on treatments...
US-9,468,626 Melatonin-based formulations for parenteral administration
Pharmaceutical formulations comprising nanoparticles of melatonin are useful for the treatment of neonatal brain injury.
US-9,468,625 Organonitro thioether compounds and medical uses thereof
The invention provides organonitro thioether compounds, compositions containing such compounds, isolated organonitro thioether compounds and methods for using...
US-9,468,624 Small molecule antagonists of bacterial quorum-sensing receptors
A novel small molecule antagonizes two types of acyl homoserine lactone receptors: membrane-bound and cytoplasmic. A focused library of analogs and derivatives...
US-9,468,623 Medical use of compound from Garcinia esculenta
The present invention provides compound extracted from Garcinia species and the use of said compound in preventing and treating cancer.
US-9,468,622 .alpha.-keto peracids and methods for producing and using the same
The present invention provides .alpha.-keto peracids and methods for producing and using the same. In particular, .alpha.-keto peracids are useful as...
US-9,468,621 Metal-salen complex compound responsive drug and intra-corporeal behavior control system for metal-salen...
A metal-salen complex compound responsive drug, which has an antidotal property capable of neutralizing cytotoxicity of a metal-salen complex compound, and an...
US-9,468,620 Methods of treating ototoxicity
The present invention relates to use of DHA analogs and their pharmaceutical compositions for treating ototoxicity, by administering these compounds or...
US-9,468,619 3,5,3'-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof
The invention regards the use of triiodothyronine sulfate, commonly named T.sub.3S, as a medicament having thyromimetic activity for the treatment of...
US-9,468,618 Topical pharmaceutical gel composition of diclofenac sodium
A topical pharmaceutical gel composition of diclofenac sodium suitable for once-a-day topical application is provided. The topical gel composition contains at...
US-9,468,617 Topical pharmaceutical gel composition of diclofenac sodium
Topical pharmaceutical gel compositions of diclofenac sodium are provided. The topical gel compositions contain at least about 10% w/w diclofenac sodium and are...
US-9,468,616 Pharmaceutical composition for preventing or treating inflammatory diseases or infectious diseases, containing...
Provided herein are a composition for preventing or treating inflammatory diseases or infectious diseases which contains m-3M3FBS or a pharmaceutically...
US-9,468,615 Use of malononitrilamides in neuropathic pain
Provided herein are compounds and pharmaceutical compositions for use in the treatment of neuropathic pain and the neuropathic pain syndromes.
US-9,468,614 Oral care method and kit
A method of moisturizing while decolonizing mammalian tissue, comprising applying a multi-valent cationic antiseptic composition to the tissue, and applying a...
US-9,468,613 Doxorubicin adjuvants to reduce toxicity and methods for using the same
Methods are provided for using doxorubicin active agents in which reduced host toxicity is observed. Aspects of the methods including administering to a subject...
US-9,468,612 Cysteamine in the treatment of fibrotic disease
Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we...
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