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Patent # Description
US-9,469,667 Metal complexes
The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, comprising these metal complexes.
US-9,469,666 Preparation of bleaching catalysts
The present invention concerns synthesizing manganese complexes in essentially non-aqueous solutions.
US-9,469,665 Compound having lysophosphatidylserine receptor function modulation activity
The object of the present invention is to provide a compound having a lysophosphatidylserine receptor function modulation activity or a salt thereof. A compound...
US-9,469,664 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups
Oligonucleotide analogs comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed compounds are useful for...
US-9,469,663 Optically compensated acrylic pressure-sensitive adhesive composition, polarizing plate and liquid crystal...
The present invention relates to an acrylic pressure-sensitive adhesive composition, a polarizing plate and a liquid crystal display device, using the same....
US-9,469,662 Process for preparing optically active biophosphinylalkanes
The present invention relates to a process for preparing optically active bisphosphinylalkanes from the correspondingly substituted, racemic 1,2-diols. The...
US-9,469,661 Hydroxyl group-containing methylstyrene and polymers incorporating same
Vulcanizates with desirable properties can be obtained from compounds incorporating polymers that include hydroxyl group-containing .alpha.-methylstyrene...
US-9,469,660 Sulfur scavenging materials comprising hexahydrotriazine-modified particle
Materials which react with ("scavenge") sulfur compounds, such as hydrogen sulfide and mercaptans, are useful for limiting sulfur-induced corrosion....
US-9,469,659 Compositions and methods for improving glucose uptake
A method of treating a disease comprising administering to a subject a therapeutically effective amount of a compound that includes the structure of general...
US-9,469,658 Lanthanide complex catalyst and polymerization method employing same
A novel class of lanthanide metal salen complexes can be used as an ingredient of a catalyst system. The catalyst system can be used in polymerizations of...
US-9,469,657 Glycosidase inhibitors
Novel compounds of formula (I) ##STR00001## wherein R.sup.1 to R.sup.4 and X have the meaning according to the claims, are glucosidase inhibitors, and can be...
US-9,469,656 HDAC inhibitors as anti-cancer agents
Largazole analogs, methods of making the same, and methods of using the same, are described.
US-9,469,655 Methods for the acylation of maytansinol
Disclosed is a method of preparing an amino acid ester of maytansinol by reacting maytansinol with an N-carboxyanhydride of an amino acid (NCA) in the presence...
US-9,469,654 Bicyclic oxa-lactam kinase inhibitors
Provided are bicyclic oxa-lactam compounds of formula I: ##STR00001## and pharmaceutically acceptable salts thereof which are inhibitors of JAK/Syk kinase. The...
US-9,469,653 Pharmaceutical compositions for preventing or treating degenerative brain disease and method of screening the same
A pharmaceutical composition for preventing or treating a degenerative brain disease, and a method of screening a material for preventing or treating a...
US-9,469,652 ERK inhibitors
The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the...
US-9,469,651 Halichondrin B analogs
The invention includes halichondrin B analogs having pharmaceutical activity; in some cases, crystalline forms thereof, and in some cases, halichondrin B...
US-9,469,650 Melampomagnolide B derivatives
The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, and thiocarbamates. The derivatives may be...
US-9,469,649 Synthetic voacangine
Synthetic voacangine, including in substantially enantiomerically enriched forms, and derivatives thereof are provided.
US-9,469,648 Reversal of drug-induced neuromuscular block using novel molecular containers
Provided are methods for reversing the effects of agents used for muscular immobilization and/or loss of consciousness and/or loss of pain perception. The...
US-9,469,647 Salt crystals
The present invention relates to acid addition salt and salt crystals of (6aR,9aS)-5,6a,7,8,9,9a-hexahydro-5-methyl-3-(phenylamino)-2-((4-(6-fluor- ...
US-9,469,646 Modulators of methyl modifying enzymes, compositions and uses thereof
Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.
US-9,469,645 Compounds and compositions for the treatment of parasitic diseases
The invention provides a class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent malaria.
US-9,469,644 Inhibitors of Bruton's tyrosine kinase
This application discloses compounds according to generic Formula (I) wherein all variables are defined as described herein, which inhibit BTK. The compounds...
US-9,469,643 Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-on- e
Polymorphs of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-on- e, compositions thereof, methods for their preparation, and methods for ...
US-9,469,642 Purinone compounds as kinase inhibitors
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition,...
US-9,469,641 Pyrido[3,4-B]indoles and methods of use
This disclosure relates to new heterocyclic compounds that may be used to modulate a histamine receptor in an individual. Compounds of formula (F) ##STR00001## ...
US-9,469,640 Compounds and methods for kinase modulation, and indications therefor
Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity...
US-9,469,639 Naphthylurea derivatives and medical applications thereof
The present invention relates to naphthylurea derivatives. Such substances can significantly inhibit VEGFR2 and PDGFR-.beta. receptor tyrosine kinase...
US-9,469,638 Substituted polycyclic carbamoylpyridone derivative
This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted...
US-9,469,637 Nitrogenated heterocyclic compound
The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of...
US-9,469,635 Stable SNS-595 compositions and methods of preparation
Methods of preparing substantially pure SNS-595 substance are disclosed. Also provided are compositions comprising SNS-595 substance that are substantially pure...
US-9,469,634 Non-nucleoside reverse transcriptase inhibitors
Compounds of Formula I: ##STR00001## are HIV reverse transcriptase inhibitors, wherein R.sup.1, R.sup.2, R.sup.E, L, M and Z are defined herein. The compounds...
US-9,469,633 Processes for the preparation of pyrrolidine intermediates
The present invention relates to processes for the enantio-selective preparation of spyrrolidine derivatives useful in the manufacture of pesticidally active...
US-9,469,632 6-substituted-3H-1,3-benzothiazol-2-one compounds as TARP-gamma 8 dependent AMPA receptor antagonists
A TARP .gamma.8 dependant AMPA receptor antagonist of the formula: ##STR00001## wherein X is CH or N; A is ##STR00002## and R.sup.1 is as defined herein; its...
US-9,469,631 N-cyclopropyl-N-piperidinyl-amides, pharmaceutical compositions containing them, and uses thereof
The present invention relates to compounds of general formula (I), wherein R.sup.1, L.sup.P, L.sup.Q, (Het)Ar, m and n are as defined in the application, which...
US-9,469,630 Sustained-release formulation for injection
The present invention relates to a composition comprising N-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]-(2R,3R)-2,3-tetramethyle- ...
US-9,469,629 NK.sub.1 antagonists
A compound having the general structure shown in Formula I: ##STR00001## or pharmaceutically acceptable salts and/or solvates thereof are useful in treating...
US-9,469,628 Processes for the preparation of highly pure Rivaroxaban crystal modification I
Provided herein are improved, commercially viable and consistently reproducible processes for the preparation of highly pure crystal Modification I of...
US-9,469,627 Phenyloxadiazole derivatives as PGDS inhibitors
This invention is directed to a compound of formula (I): ##STR00001## wherein R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising the...
US-9,469,626 Biorefining compounds and organocatalytic upgrading methods
The invention provides new methods for the direct umpolung self-condensation of 5-hydroxymethylfurfural (HMF) by organocatalysis, thereby upgrading the readily...
US-9,469,625 Organic compounds
The invention relates to compounds and methods of treatment relating to nicotinic receptor antagonists. For example, the compounds and methods of treatment...
US-9,469,624 Integrated process for producing cyclic acetals and oxymethylene polymers
A process for producing cyclic acetals is described. A formaldehyde source is contacted with an aprotic compound in the presence of a catalyst to produce the...
US-9,469,623 Preparation method for optically active bicyclic gamma-amino acid compound
An object of the present invention is to provide an optically active bicyclic .gamma.-amino acid derivative in a high purity. The object can be attained by a...
US-9,469,622 Process for the cyclodehydration of diols and use thereof for the manufacturing of ambrafuran and other...
A process for manufacturing tetrahydrofuran, tetrahydropyran and, more generally, cycloether derivatives through the cyclodehydration of 1,4- or 1,5-diols. More...
US-9,469,621 Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein
A method for producing a multisubstituted biphenyl compound is represented by the following formula (2), including a step of coupling a substituted benzene...
US-9,469,620 Process for forming a primary, a secondary or a tertiary amine via a direct amination reaction
The present invention concerns a process to obtain primary, secondary or tertiary amines, via a direct amination reaction of alcohols in presence of...
US-9,469,619 Method of preparing furfural compounds
Provided is a two-step method of producing a compound of chemical formula 1 in the presence of an alcohol solvent and a Group 3B metal catalyst or a salt...
US-9,469,618 Thiadiazolidinediones as GSK-3 inhibitors
The present invention relates to new thiadiazolidinediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in...
US-9,469,617 Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce...
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