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Patent # Description
US-9,474,755 GLP-1 receptor modulators
Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic...
US-9,474,754 Pharmaceutical combinations comprising a B-RAF inhibitor, and EGFR inhibitor and optionally a PI3K-.alpha....
A pharmaceutical combination comprising (a) a B-Raf inhibitor, (b) a EGFR inhibitor and, optionally, (c) a PI3K inhibitor; the uses of such combination in the...
US-9,474,753 Treating neural disease with tyrosine kinase inhibitors
Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising...
US-9,474,752 Method for treating a pulmonary hypertension condition
A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a...
US-9,474,751 Combination of brimonidine and timolol for topical ophthalmic use
Disclosed are pharmaceutical compositions comprising brimonidine and timolol for topical ophthalmic delivery and a method of treatment comprising administering...
US-9,474,750 Opioid agonist/opioid antagonist/acetaminophen combinations
The invention is directed in part to oral dosage forms comprising a combination of an opioid agonist, acetaminophen and an orally active opioid antagonist, the...
US-9,474,749 Morphine and morphine precursors
Methods and materials related to the use of morphine, morphine precursors (e.g., reticuline), and inhibitors of morphine synthesis or activity to treat...
US-9,474,748 Adjuvant chemotherapy for anaplastic gliomas
The present invention involves the use of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) in the treatment and prevention of gliomas. The 2,4-ds-PBN may...
US-9,474,747 Muscarinic antagonists and combinations thereof for the treatment of airway disease in horses
The invention relates to the field of medicine, in particular to the field of veterinary medicine. The invention specifically relates to muscarinic antagonists...
US-9,474,746 Methods for stabilizing oxidatively unstable compositions
Ophthalmic compositions and methods of preparing such compositions are disclosed.
US-9,474,745 Use of FK506 for the treatment of pulmonary arterial hypertension
A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering...
US-9,474,744 Beta-lactam compounds for treating diabetes
Compositions and methods comprising ampicillin or salts and derivative thereof for the treatment of delaying the onset of type I diabetes are provided.
US-9,474,743 Compositions for an orally active 1,2,4-oxadiazole for the treatment of disease
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases...
US-9,474,742 Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for...
The present disclosure provides substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes, of Formula I D-M-D ...
US-9,474,741 Use of NK-1 receptor antagonists in pruritus
The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical...
US-9,474,740 Ectoparasite control agent
##STR00001## wherein, in formula (III), X.sup.1 represents a C1-6 alkyl group which is unsubstituted or has a substituent, or other groups; m1 represents any...
US-9,474,739 Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel...
Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,...
US-9,474,738 Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel...
Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,...
US-9,474,737 Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel...
Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,...
US-9,474,736 Composition and method for treating dry eye syndrome
The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More...
US-9,474,735 Liver function improvement and treatment of liver disease
A pharmaceutical preparation containing polymeric compounds as shown in the specification. This preparation can be used to improve liver function and treat...
US-9,474,734 Compounds for treating inflammation and pain
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and 3-(methylthio)propionitrile, or a...
US-9,474,733 Method and preparation for binding acetaldehyde in saliva, stomach and large intestine
The object of the invention is the use of compounds comprising one or more free sulphlydryl or amino groups for preparing a pharmaceutical composition for...
US-9,474,732 Intrathecal baclofen pharmaceutical dosage forms with fewer degradation products
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% of ...
US-9,474,731 Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
US-9,474,730 Methods and compositions for use with K-ras mediated disorders
Methods and compositions that can be used to identify and characterize inhibitors of K-ras localization to the plasma membrane and in doing so inhibit the...
US-9,474,729 Topical antimicrobial compositions and methods of using same
The invention includes a method of treating a mammal comprising topically applying an aqueous composition to a target site on the mammal, wherein the aqueous...
US-9,474,728 Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine
The present invention relates to methods for the treatment or prevention of fatigue associated with disordered sleep, for example, in multiple sclerosis,...
US-9,474,727 Pharmaceutical compositions of curcumin
The present invention relates to stable liquid pharmaceutical compositions of curcumin or its pharmaceutically acceptable salts or its derivatives with higher...
US-9,474,726 Use of cannabinoids in the treatment of epilepsy
The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of "treatment-resistant...
US-9,474,725 Food and beverage compositions infused with lipophilic active agents and methods of use thereof
Aspects described herein relate to food and beverage compositions infused with lipophilic active agents and methods of use for the treatment of a variety of...
US-9,474,724 Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye...
Oral formulations for promoting eye health, and in particular for preventing or treating macular degeneration, are disclosed, containing zeaxanthin, a...
US-9,474,723 Anti-microbial composition
This invention pertains to an anti-microbial, in particular anti-bacterial and/or anti-fungal composition comprising cinnamaldehyde, trans-2-methoxy...
US-9,474,722 Compositions and methods for transdermal delivery of amphetamine
Compositions for the transdermal delivery of amphetamine in a flexible, finite form are described. The compositions comprise a polymer matrix that includes...
US-9,474,721 Abuse-resistant formulations
The disclosure relates to a sustained-release oral dosage form for once-a-day administration comprising a matrix containing a viscosity modifier and coated...
US-9,474,720 Dosage form comprising an active ingredient and a plurality of solid porous microcarriers
The present application provides a dosage form and related methods for making the dosage form. The dosage form generally comprises a hydrophilic active...
US-9,474,719 Pulsatile drug release
In one aspect, the present invention is concerned with a treatment where it is desired that an active agent is designed to be released in a pulse at a time...
US-9,474,718 Collagen powder, composition and use
Collagen powder in which at least 99.5% of the particles have a maximum size of 80 microns 25% to 45% by volume of the particles have a size of more than 30...
US-9,474,717 Vaccine nanotechnology
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers...
US-9,474,716 SiRNA phospholipid conjugate
siRNA-conjugated liposomes and micelles, methods of making such conjugates, and methods of using such conjugates, such as for the delivery of siRNA to cells to...
US-9,474,715 Polymeric drug-delivery material, method for manufacturing thereof and method for delivery of a drug-delivery...
A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a...
US-9,474,714 Solid pharmaceutical composition of cation exchange resin
The present invention relates to a solid pharmaceutical cation-exchange resin composition allowing the preparation of a stable resin suspension in an aqueous...
US-9,474,713 Chewable composition for oral administration and process for preparing thereof
The present invention relates to chewable compositions for oral administration, said compositions comprising high(methyl)pectin, glycerol and water....
US-9,474,712 In situ reaction device
Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are...
US-9,474,711 Extract of Kniphofia uvaria seeds, cosmetic or dermatological composition containing same, and uses thereof
An extract of the seeds of the Kniphofia uvaria plant is obtained by bringing into contact with at least one cosmetically acceptable nonpolar solvent, for...
US-9,474,710 Mascara composition
A mascara composition including at least one olefin/acrylate grafted polymer and at least one acrylates copolymer. The ratio of the weight amount of the...
US-9,474,709 Natural moisturizing composition for promotion of healing and treatment of skin disorders
A preferred embodiment of a version of the invention is directed to a skin moisturizing composition for the treatment of a variety of skin disorders, including...
US-9,474,708 Tritightening skin care formulation
The present invention provides for a formulation comprising: at least one hydrophilic polymer, at least one desquamatory agent and alpha hydroxyl acid.
US-9,474,707 Optical treatment methods
A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects...
US-9,474,706 Composition for maintaining effect of filler
The present invention relates to a composition for maintaining efficacy of a filler for a long period of time by containing collagen as an active ingredient....
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