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Patent # | Description |
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US-9,474,755 |
GLP-1 receptor modulators Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic... |
US-9,474,754 |
Pharmaceutical combinations comprising a B-RAF inhibitor, and EGFR
inhibitor and optionally a PI3K-.alpha.... A pharmaceutical combination comprising (a) a B-Raf inhibitor, (b) a EGFR inhibitor and, optionally, (c) a PI3K inhibitor; the uses of such combination in the... |
US-9,474,753 |
Treating neural disease with tyrosine kinase inhibitors Provided herein are methods of treating or preventing a neurodegenerative disease, a myodegenerative disease or a prion disease in a subject comprising... |
US-9,474,752 |
Method for treating a pulmonary hypertension condition A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a... |
US-9,474,751 |
Combination of brimonidine and timolol for topical ophthalmic use Disclosed are pharmaceutical compositions comprising brimonidine and timolol for topical ophthalmic delivery and a method of treatment comprising administering... |
US-9,474,750 |
Opioid agonist/opioid antagonist/acetaminophen combinations The invention is directed in part to oral dosage forms comprising a combination of an opioid agonist, acetaminophen and an orally active opioid antagonist, the... |
US-9,474,749 |
Morphine and morphine precursors Methods and materials related to the use of morphine, morphine precursors (e.g., reticuline), and inhibitors of morphine synthesis or activity to treat... |
US-9,474,748 |
Adjuvant chemotherapy for anaplastic gliomas The present invention involves the use of 2,4-disulfonyl phenyl tert-butyl nitrone (2,4-ds-PBN) in the treatment and prevention of gliomas. The 2,4-ds-PBN may... |
US-9,474,747 |
Muscarinic antagonists and combinations thereof for the treatment of
airway disease in horses The invention relates to the field of medicine, in particular to the field of veterinary medicine. The invention specifically relates to muscarinic antagonists... |
US-9,474,746 |
Methods for stabilizing oxidatively unstable compositions Ophthalmic compositions and methods of preparing such compositions are disclosed. |
US-9,474,745 |
Use of FK506 for the treatment of pulmonary arterial hypertension A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering... |
US-9,474,744 |
Beta-lactam compounds for treating diabetes Compositions and methods comprising ampicillin or salts and derivative thereof for the treatment of delaying the onset of type I diabetes are provided. |
US-9,474,743 |
Compositions for an orally active 1,2,4-oxadiazole for the treatment of
disease The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases... |
US-9,474,742 |
Substituted aliphanes, cyclophanes, heteraphanes, heterophanes,
hetero-heteraphanes and metallocenes useful for... The present disclosure provides substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes, of Formula I D-M-D ... |
US-9,474,741 |
Use of NK-1 receptor antagonists in pruritus The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical... |
US-9,474,740 |
Ectoparasite control agent ##STR00001## wherein, in formula (III), X.sup.1 represents a C1-6 alkyl group which is unsubstituted or has a substituent, or other groups; m1 represents any... |
US-9,474,739 |
Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their
use as sodium and/or calcium channel... Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,... |
US-9,474,738 |
Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their
use as sodium and/or calcium channel... Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,... |
US-9,474,737 |
Substituted 2-[2-(phenyl) ethylamino] alkaneamide derivatives and their
use as sodium and/or calcium channel... Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives of formula (I) ##STR00001## wherein X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3, R'.sub.3 R.sub.4,... |
US-9,474,736 |
Composition and method for treating dry eye syndrome The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More... |
US-9,474,735 |
Liver function improvement and treatment of liver disease A pharmaceutical preparation containing polymeric compounds as shown in the specification. This preparation can be used to improve liver function and treat... |
US-9,474,734 |
Compounds for treating inflammation and pain The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and 3-(methylthio)propionitrile, or a... |
US-9,474,733 |
Method and preparation for binding acetaldehyde in saliva, stomach and
large intestine The object of the invention is the use of compounds comprising one or more free sulphlydryl or amino groups for preparing a pharmaceutical composition for... |
US-9,474,732 |
Intrathecal baclofen pharmaceutical dosage forms with fewer degradation
products The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% of ... |
US-9,474,731 |
Compositions and methods for increasing the metabolic lifetime of
dextromethorphan and related pharmacodynamic... This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,... |
US-9,474,730 |
Methods and compositions for use with K-ras mediated disorders Methods and compositions that can be used to identify and characterize inhibitors of K-ras localization to the plasma membrane and in doing so inhibit the... |
US-9,474,729 |
Topical antimicrobial compositions and methods of using same The invention includes a method of treating a mammal comprising topically applying an aqueous composition to a target site on the mammal, wherein the aqueous... |
US-9,474,728 |
Methods and compositions for treating fatigue associated with disordered
sleep using very low dose cyclobenzaprine The present invention relates to methods for the treatment or prevention of fatigue associated with disordered sleep, for example, in multiple sclerosis,... |
US-9,474,727 |
Pharmaceutical compositions of curcumin The present invention relates to stable liquid pharmaceutical compositions of curcumin or its pharmaceutically acceptable salts or its derivatives with higher... |
US-9,474,726 |
Use of cannabinoids in the treatment of epilepsy The present disclosure relates to the use of cannabidiol (CBD) for the reduction of total convulsive seizure frequency in the treatment of "treatment-resistant... |
US-9,474,725 |
Food and beverage compositions infused with lipophilic active agents and
methods of use thereof Aspects described herein relate to food and beverage compositions infused with lipophilic active agents and methods of use for the treatment of a variety of... |
US-9,474,724 |
Zeaxanthin formulations with additional ocular-active nutrients, for
protecting eye health and treating eye... Oral formulations for promoting eye health, and in particular for preventing or treating macular degeneration, are disclosed, containing zeaxanthin, a... |
US-9,474,723 |
Anti-microbial composition This invention pertains to an anti-microbial, in particular anti-bacterial and/or anti-fungal composition comprising cinnamaldehyde, trans-2-methoxy... |
US-9,474,722 |
Compositions and methods for transdermal delivery of amphetamine Compositions for the transdermal delivery of amphetamine in a flexible, finite form are described. The compositions comprise a polymer matrix that includes... |
US-9,474,721 |
Abuse-resistant formulations The disclosure relates to a sustained-release oral dosage form for once-a-day administration comprising a matrix containing a viscosity modifier and coated... |
US-9,474,720 |
Dosage form comprising an active ingredient and a plurality of solid
porous microcarriers The present application provides a dosage form and related methods for making the dosage form. The dosage form generally comprises a hydrophilic active... |
US-9,474,719 |
Pulsatile drug release In one aspect, the present invention is concerned with a treatment where it is desired that an active agent is designed to be released in a pulse at a time... |
US-9,474,718 |
Collagen powder, composition and use Collagen powder in which at least 99.5% of the particles have a maximum size of 80 microns 25% to 45% by volume of the particles have a size of more than 30... |
US-9,474,717 |
Vaccine nanotechnology The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers... |
US-9,474,716 |
SiRNA phospholipid conjugate siRNA-conjugated liposomes and micelles, methods of making such conjugates, and methods of using such conjugates, such as for the delivery of siRNA to cells to... |
US-9,474,715 |
Polymeric drug-delivery material, method for manufacturing thereof and
method for delivery of a drug-delivery... A method for manufacturing a drug-delivery composition includes providing at least one pharmaceutically active compound, a dry powder comprising at least a... |
US-9,474,714 |
Solid pharmaceutical composition of cation exchange resin The present invention relates to a solid pharmaceutical cation-exchange resin composition allowing the preparation of a stable resin suspension in an aqueous... |
US-9,474,713 |
Chewable composition for oral administration and process for preparing
thereof The present invention relates to chewable compositions for oral administration, said compositions comprising high(methyl)pectin, glycerol and water.... |
US-9,474,712 |
In situ reaction device Embodiments of a system including a remotely controlled reaction device and associated controller are described. Methods of use and control of the device are... |
US-9,474,711 |
Extract of Kniphofia uvaria seeds, cosmetic or dermatological composition
containing same, and uses thereof An extract of the seeds of the Kniphofia uvaria plant is obtained by bringing into contact with at least one cosmetically acceptable nonpolar solvent, for... |
US-9,474,710 |
Mascara composition A mascara composition including at least one olefin/acrylate grafted polymer and at least one acrylates copolymer. The ratio of the weight amount of the... |
US-9,474,709 |
Natural moisturizing composition for promotion of healing and treatment of
skin disorders A preferred embodiment of a version of the invention is directed to a skin moisturizing composition for the treatment of a variety of skin disorders, including... |
US-9,474,708 |
Tritightening skin care formulation The present invention provides for a formulation comprising: at least one hydrophilic polymer, at least one desquamatory agent and alpha hydroxyl acid. |
US-9,474,707 |
Optical treatment methods A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects... |
US-9,474,706 |
Composition for maintaining effect of filler The present invention relates to a composition for maintaining efficacy of a filler for a long period of time by containing collagen as an active ingredient.... |